Ceramic Nanomaterials in Dental Applications

The aim of this work was to reduce microleakage in giomer restorations by using innovative materials in both adhesive systems and light-cured dental giomer. Two adhesive systems with different primers were investigated. The innovative compounds in the primers were acrylic acid (AA)/itaconic acid (IA) copolymer modified with methacrylic groups and AA/IA/N-acryloyl-L-leucine copolymer grafted with methacrylic groups. In addition, the investigated new giomer G contains a pre-reacted glass based on the latter copolymer. The commercial Beautifil II giomer and the FL-Bond II adhesive system were used for comparison. Microleakage was evaluated by determining the scores and percentages of dye penetration lengths after thermocycling of a series of light-cured dental giomer restorations performed on 42 premolars extracted for orthodontic reasons. A lower microleakage value was recorded for the adhesive system containing the AA/IA/N-acryloyl-L-leucine copolymer grafted with methacrylic groups than for the commercial adhesive, which was in substantial agreement with SEM and AFM investigations. In this case, remarkable dentin sealing and a strong adhesion at the giomer restoration�tooth interface was observed, and the innovative adhesive was proven to be promising for dental applications.

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Review on Development and Dental Applications of Polyetheretherketone-Based Biomaterials and Restorations

Materials ◽

10.3390/ma14020408 ◽

2021 ◽

Vol 14 (2) ◽

pp. 408 ◽

Cited By ~ 1

Author(s):

Ludan Qin ◽

Shuo Yao ◽

Jiaxin Zhao ◽

Chuanjian Zhou ◽

Thomas W. Oates ◽

...

Keyword(s):

High Performance ◽

Dental Resin ◽

Oral Environment ◽

Inert Surface ◽

Oral Implant ◽

Long Term Performance ◽

Dental Applications ◽

Term Performance ◽

Orthopedic Applications

Polyetheretherketone (PEEK) is an important high-performance thermoplastic. Its excellent strength, stiffness, toughness, fatigue resistance, biocompatibility, chemical stability and radiolucency have made PEEK attractive in dental and orthopedic applications. However, PEEK has an inherently hydrophobic and chemically inert surface, which has restricted its widespread use in clinical applications, especially in bonding with dental resin composites. Cutting edge research on novel methods to improve PEEK applications in dentistry, including oral implant, prosthodontics and orthodontics, is reviewed in this article. In addition, this article also discusses innovative surface modifications of PEEK, which are a focus area of active investigations. Furthermore, this article also discusses the necessary future studies and clinical trials for the use of PEEK in the human oral environment to investigate its feasibility and long-term performance.

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Chapter 16. Dental applications

Nickel-Titanium Materials ◽

10.1515/9783110666113-016 ◽

2020 ◽

pp. 670-864

Keyword(s):

Dental Applications

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Graphene-Doped Poly (Methyl-Methacrylate) (Pmma) Implants: A Micro-CT and Histomorphometrical Study in Rabbits

International Journal of Molecular Sciences ◽

10.3390/ijms22031441 ◽

2021 ◽

Vol 22 (3) ◽

pp. 1441

Author(s):

Antonio Scarano ◽

Tiziana Orsini ◽

Fabio Di Carlo ◽

Luca Valbonetti ◽

Felice Lorusso

Keyword(s):

Methyl Methacrylate ◽

Dental Implant ◽

Animal Studies ◽

White Male ◽

Biological Response ◽

Medullary Canal ◽

Poly Methyl Methacrylate ◽

Titanium Surfaces ◽

Dental Applications

Background—the graphene-doping procedure represents a useful procedure to improve the mechanical, physical and biological response of several Polymethyl methacrylate (PMMA)-derived polymers and biomaterials for dental applications. The aim of this study was to evaluate osseointegration of Graphene doped Poly(methyl methacrylate) (GD-PMMA) compared with PMMA as potential materials for dental implant devices. Methods—eighteen adult New Zealand white male rabbits with a mean weight of approx. 3000 g were used in this research. A total of eighteen implants of 3.5 mm diameter and 11 mm length in GD-PMMA and eighteen implants in PMMA were used. The implants were placed into the articular femoral knee joint. The animals were sacrificed after 15, 30 and 60 days and the specimens were evaluated by µCT and histomorphometry. Results—microscopically, all 36 implants, 18 in PMMA and 18 in DG-PMMA were well-integrated into the bone. The implants were in contact with cortical bone along the upper threads, while the lower threads were in contact with either newly formed bone or with marrow spaces. The histomorphometry and µCT evaluation showed that the GP-PMMA and PMMA implants were well osseointegrated and the bone was in direct contact with large portions of the implant surfaces, including the space in the medullary canal. Conclusions—in conclusion, the results suggest that GD-PMMA titanium surfaces enhance osseointegration in rabbit femurs. This encourages further research to obtain GD-PMMA with a greater radiopacity. Also, further in vitro and vivo animal studies are necessary to evaluate a potential clinical usage for dental implant applications.

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Novel bioinspired composites fabricated by robocasting for dental applications

Ceramics International ◽

10.1016/j.ceramint.2021.04.142 ◽

2021 ◽

Author(s):

Francisco J. Martínez-Vázquez ◽

Estíbaliz Sánchez-González ◽

Oscar Borrero-López ◽

Pedro Miranda ◽

Antonia Pajares ◽

...

Keyword(s):

Dental Applications

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Assessment of Mechanical, Chemical, and Biological Properties of Ti-Nb-Zr Alloy for Medical Applications

Materials ◽

10.3390/ma14010126 ◽

2020 ◽

Vol 14 (1) ◽

pp. 126

Author(s):

Viktoria Hoppe ◽

Patrycja Szymczyk-Ziółkowska ◽

Małgorzata Rusińska ◽

Bogdan Dybała ◽

Dominik Poradowski ◽

...

Keyword(s):

Mechanical Properties ◽

Corrosion Resistance ◽

Base Material ◽

Biological Properties ◽

Β Phase ◽

Alloy Base ◽

Static Tensile ◽

Examination Methods ◽

13Zr Alloy ◽

Dental Applications

The purpose of this work is to obtain comprehensive reference data of the Ti-13Nb-13Zr alloy base material: its microstructure, mechanical, and physicochemical properties. In order to obtain extensive information on the tested materials, a number of examination methods were used, including SEM, XRD, and XPS to determine the phases occurring in the material, while mechanical properties were verified with static tensile, compression, and bending tests. Moreover, the alloy’s corrosion resistance in Ringer’s solution and the cytotoxicity were investigated using the MTT test. Studies have shown that this alloy has the structure α’, α, and β phases, indicating that parts of the β phase transformed to α’, which was confirmed by mechanical properties and the shape of fractures. Due to the good mechanical properties (E = 84.1 GPa), high corrosion resistance, as well as the lack of cytotoxicity on MC3T3 and NHDF cells, this alloy meets the requirements for medical implant materials. Ti-13Nb-13Zr alloy can be successfully used in implants, including bone tissue engineering products and dental applications.

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Dental Applications of Carbon Nanotubes

Molecules ◽

10.3390/molecules26154423 ◽

2021 ◽

Vol 26 (15) ◽

pp. 4423

Author(s):

Marco A. Castro-Rojas ◽

Yadira I. Vega-Cantu ◽

Geoffrey A. Cordell ◽

Aida Rodriguez-Garcia

Keyword(s):

Mechanical Properties ◽

Carbon Nanotubes ◽

Oral Cavity ◽

Current Status ◽

Glass Ionomer ◽

Oral Infections ◽

Functional Behavior ◽

The Status ◽

Comprehensive Survey ◽

Dental Applications

Glass ionomer cements and resin-based composites are promising materials in restorative dentistry. However, their limited mechanical properties and the risk of bulk/marginal fracture compromise their lifespan. Intensive research has been conducted to understand and develop new materials that can mimic the functional behavior of the oral cavity. Nanotechnological approaches have emerged to treat oral infections and become a part of scaffolds for tissue regeneration. Carbon nanotubes are promising materials to create multifunctional platforms for dental applications. This review provides a comprehensive survey of and information on the status of this state-of-the-art technology and describes the development of glass ionomers reinforced with carbon nanotubes possessing improved mechanical properties. The applications of carbon nanotubes in drug delivery and tissue engineering for healing infections and lesions of the oral cavity are also described. The review concludes with a summary of the current status and presents a vision of future applications of carbon nanotubes in the practice of dentistry.

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Design and characterization of digluconate and diacetate chlorhexidine loaded-PLGA microparticles for dental applications

Journal of Drug Delivery Science and Technology ◽

10.1016/j.jddst.2021.102361 ◽

2021 ◽

Vol 62 ◽

pp. 102361

Author(s):

F.F.O. Sousa ◽

J.S. Nojosa ◽

C.A.A. Alencar ◽

A.P.M.P. Alcantara ◽

R.S. Araújo ◽

...

Keyword(s):

Plga Microparticles ◽

Dental Applications

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Three-Dimensional Zirconia-Based Scaffolds for Load-Bearing Bone-Regeneration Applications: Prospects and Challenges

Materials ◽

10.3390/ma14123207 ◽

2021 ◽

Vol 14 (12) ◽

pp. 3207

Author(s):

Kumaresan Sakthiabirami ◽

Vaiyapuri Soundharrajan ◽

Jin-Ho Kang ◽

Yunzhi Peter Yang ◽

Sang-Won Park

Keyword(s):

Bone Regeneration ◽

Biological Activities ◽

Three Dimensional ◽

In Vivo Studies ◽

High Mechanical Strength ◽

Real World Applications ◽

3D Fabrication ◽

Dental Applications

The design of zirconia-based scaffolds using conventional techniques for bone-regeneration applications has been studied extensively. Similar to dental applications, the use of three-dimensional (3D) zirconia-based ceramics for bone tissue engineering (BTE) has recently attracted considerable attention because of their high mechanical strength and biocompatibility. However, techniques to fabricate zirconia-based scaffolds for bone regeneration are in a stage of infancy. Hence, the biological activities of zirconia-based ceramics for bone-regeneration applications have not been fully investigated, in contrast to the well-established calcium phosphate-based ceramics for bone-regeneration applications. This paper outlines recent research developments and challenges concerning numerous three-dimensional (3D) zirconia-based scaffolds and reviews the associated fundamental fabrication techniques, key 3D fabrication developments and practical encounters to identify the optimal 3D fabrication technique for obtaining 3D zirconia-based scaffolds suitable for real-world applications. This review mainly summarized the articles that focused on in vitro and in vivo studies along with the fundamental mechanical characterizations on the 3D zirconia-based scaffolds.

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Three-Dimensional Printing of Hydroxyapatite Composites for Biomedical Application

Crystals ◽

10.3390/cryst11040353 ◽

2021 ◽

Vol 11 (4) ◽

pp. 353

Author(s):

Yanting Han ◽

Qianqian Wei ◽

Pengbo Chang ◽

Kehui Hu ◽

Oseweuba Valentine Okoro ◽

...

Keyword(s):

Tissue Engineering ◽

3D Printing ◽

Biomedical Application ◽

Three Dimensional ◽

Antibacterial Properties ◽

Natural Polymers ◽

Three Dimensional Printing ◽

3D Printed ◽

Dental Applications ◽

Hard Tissue Engineering

Hydroxyapatite (HA) and HA-based nanocomposites have been recognized as ideal biomaterials in hard tissue engineering because of their compositional similarity to bioapatite. However, the traditional HA-based nanocomposites fabrication techniques still limit the utilization of HA in bone, cartilage, dental, applications, and other fields. In recent years, three-dimensional (3D) printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds. This review therefore explores available 3D printing technologies for the preparation of porous HA-based nanocomposites. In the present review, different 3D printed HA-based scaffolds composited with natural polymers and/or synthetic polymers are discussed. Furthermore, the desired properties of HA-based composites via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored. Lastly, the applications and the next generation of HA-based nanocomposites for tissue engineering are discussed.

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