Metal–Organic Framework Modified MoS 2 Nanozyme for Synergetic Combating Drug‐Resistant Bacterial Infections via Photothermal Effect and Photodynamic Modulated Peroxidase‐Mimic Activity

2021 ◽  
pp. 2101698
Author(s):  
Zi‐Yang Liao ◽  
Ya‐Mu Xia ◽  
Jia‐Min Zuo ◽  
Tao Wang ◽  
Da‐Tong Hu ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Metal Organic Framework ◽  
Photothermal Effect ◽  
Drug Resistant ◽  
Peroxidase Mimic ◽  
Metal Organic ◽  
Organic Framework

Designing inhalable metal organic frameworks for pulmonary tuberculosis treatment and theragnostics via spray drying

2020 ◽  
Vol 56 (87) ◽  
pp. 13339-13342
Author(s):  
Ignacio Luz ◽  
Ian E. Stewart ◽  
Ninell P. Mortensen ◽  
Anthony J. Hickey
Keyword(s):  
Pulmonary Tuberculosis ◽  
Spray Drying ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Tuberculosis Treatment ◽  
Drug Resistant ◽  
Metal Organic ◽  
Organic Framework

Inhalable metal organic framework (MOF) aerosols have been developed via spray drying as a therapy for multi-drug resistant (MDR) tuberculosis (TB).

Near-infrared photothermal performance of a metal organic framework-based composite

2021 ◽  
Author(s):  
Rong Cao ◽  
Sun Jing ◽  
Kuan Pang ◽  
Tianfu Liu ◽  
Jibin Song
Keyword(s):  
Near Infrared ◽  
Metal Organic Framework ◽  
Hot Electrons ◽  
Photothermal Effect ◽  
Universal Method ◽  
Metal Organic ◽  
Organic Framework

Constructing heterostructure is a universal method to hinder the radiation recombination of hot electrons and hot holes, which can effectively enhance the photothermal effect of semiconductor. In this work, a...

A nanosized metal–organic framework of Fe-MIL-88NH2 as a novel peroxidase mimic used for colorimetric detection of glucose

The Analyst ◽  
2013 ◽  
Vol 138 (16) ◽  
pp. 4526 ◽  
Author(s):  
Ya Li Liu ◽  
Xi Juan Zhao ◽  
Xiao Xi Yang ◽  
Yuan Fang Li
Keyword(s):  
Metal Organic Framework ◽  
Colorimetric Detection ◽  
Peroxidase Mimic ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Stable DNA Aptamer–Metal–Organic Framework as Horseradish Peroxidase Mimic for Ultra-Sensitive Detection of Carcinoembryonic Antigen in Serum

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 181
Author(s):  
Lingjun Sha ◽  
Mingcong Zhu ◽  
Fuqing Lin ◽  
Xiaomeng Yu ◽  
Langjian Dong ◽  
...  
Keyword(s):  
Horseradish Peroxidase ◽  
Carcinoembryonic Antigen ◽  
Limit Of Detection ◽  
Detection System ◽  
Metal Organic Framework ◽  
Dna Aptamer ◽  
Sensitive Detection ◽  
Peroxidase Mimic ◽  
Metal Organic ◽  
Organic Framework

Carcinoembryonic antigen (CEA) is an important broad-spectrum tumor marker. For CEA detection, a novel type of metal–organic framework (MOF) was prepared by grafting CEA aptamer-incorporated DNA tetrahedral (TDN) nanostructures into PCN-222 (Fe)-based MOF (referred as CEAapt-TDN-MOF colloid nanorods). The synthesized CEAapt-TDN-MOF is a very stable detection system due to the vertex phosphorylated TDN structure at the interface, possessing a one-year shelf-life. Moreover, it exhibits a significant horseradish peroxidase mimicking activity due to the iron porphyrin ring, which leads to a colorimetric reaction upon binding toward antibody-captured CEA. Using this method, we successfully achieved the highly specific and ultra-sensitive detection of CEA with a limit of detection as low as 3.3 pg/mL. In addition, this method can detect and analyze the target proteins in clinical serum samples, effectively identify the difference between normal individuals and patients with colon cancer, and provide a new method for the clinical diagnosis of tumors, demonstrating a great application potential.

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