Broad‐spectrum antimicrobial activity of cinnamoyl esterase‐producing lactobacilli and their application in fermented rice bran

Author(s):  
Jong‐Hui Kim ◽  
Eun‐Seon Lee ◽  
Bu‐Min Kim ◽  
Jun‐Sang Ham ◽  
Mi‐Hwa Oh
2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Hussein A Kadhum ◽  
Thualfakar H Hasan2

The study involved the selection of two isolates from Bacillus subtilis to investigate their inhibitory activity against some bacterial pathogens. B sub-bacteria were found to have a broad spectrum against test bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. They were about 23-30 mm and less against Klebsiella sp. The sensitivity of some antibodies was tested on the test samples. The results showed that the inhibitory ability of bacterial growth in the test samples using B. subtilis extract was more effective than the antibiotics used.


2003 ◽  
Vol 95 (5) ◽  
pp. 1143-1151 ◽  
Author(s):  
I. Weid ◽  
D.S. Alviano ◽  
A.L.S. Santos ◽  
R.M.A. Soares ◽  
C.S. Alviano ◽  
...  

2015 ◽  
Vol 3 (4) ◽  
Author(s):  
Qihui Hou ◽  
Chengqiang Wang ◽  
Xiaoyang Hou ◽  
Zhilin Xia ◽  
Jiangping Ye ◽  
...  

Brevibacillus brevis DZQ7 is a plant growth-promoting rhizobacterium (PGPR) isolated from tobacco rhizosphere. Here, we report the draft genome sequence of B. brevis DZQ7. Several functional genes related to antimicrobial activity were identified in the genome.


Microbiology ◽  
2018 ◽  
Vol 164 (9) ◽  
pp. 1072-1086 ◽  
Author(s):  
Fernando Uriel Rojas-Rojas ◽  
Anuar Salazar-Gómez ◽  
María Elena Vargas-Díaz ◽  
María Soledad Vásquez-Murrieta ◽  
Ann M. Hirsch ◽  
...  

1997 ◽  
Vol 65 (6) ◽  
pp. 2396-2401 ◽  
Author(s):  
E M Porter ◽  
E van Dam ◽  
E V Valore ◽  
T Ganz

2019 ◽  
Vol 70 (7) ◽  
pp. 2571-2573
Author(s):  
Alina Andreea Tischer (Tucuina) ◽  
Delia Berceanu Vaduva ◽  
Nicolae Balica ◽  
Alina Heghes ◽  
Adelina Cheveresan ◽  
...  

In recent years, bacterial infections in hospitals have grown particularly due to the development of antibiotic resistance. Recent research targets the discovery of new antibiotics that exhibit broad spectrum of action without adverse effects or minimizing adverse effects. In this study, the activity of biosynthesized silver nanoparticles against three bacteria commonly found in infectious diseases in the ORL sphere was evaluated. The recorded data revealed an activity comparable to that of the standard antibiotics used in these types of infections, with the observation that the activity of the nanoparticles could also be observed in the particular cases of antibiotic resistance.


2014 ◽  
Vol 59 (4) ◽  
pp. 412-421 ◽  
Author(s):  
A. Abedini ◽  
V. Roumy ◽  
S. Mahieux ◽  
A. Gohari ◽  
M.M. Farimani ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Negero Gemeda ◽  
Ashenif Tadele ◽  
Hirut Lemma ◽  
Biruktawit Girma ◽  
Getachew Addis ◽  
...  

Background. Skin infections were the most frequently encountered of all infections and the 4th leading cause of nonfatal disease burden. Topical drugs have been used for the management of skin infections. The growing concern of drug resistance to the topical agents has warned the need for continuous development of novel drug. Essential oils are the best candidate for new drug with different mode of action and target as they are rich in chemical constituents. Objective. To evaluate and develop safe and effective topical antimicrobial formulations from essential oil of Cymbopogon martini. Method. Essential oil was extracted using hydrodistillation aerial part C. martini and topical formulations were prepared in five different semisolid bases. In vitro antimicrobial investigations were performed on essential oil and topical formulations. Skin sensitizations of the formulations were evaluated using guinea pig maximization. Results. The essential oil of C. martini has shown broad-spectrum antimicrobial potency against all tested organisms with MIC value ranging from 0.65 to 10 μg/ml. Absolute inhibitions of growth of fungi were observed against Trichophyton mentagrophytes and Trichophyton rubrum at concentrations above 1% of oil and against Microsporum canis and Trichophyton verrucosum at a concentration of 4% oil. Among topical formulations, the highest antimicrobial activity was recorded in hydrophilic ointment followed by macrogol blend ointment. The antimicrobial activity of oil was higher in fungal pathogen compared to bacteria. Gram positive bacteria were more sensitive than gram negative bacteria. Hydrophilic and macrogol blend ointment containing 5% oil did not produce any skin sensitization on guinea pigs. Conclusion. In conclusion, topical formulations of C. martini essential oil can be alternative topical agents with safe broad-spectrum activity for the treatment of skin disorder. Further studies should focus on shelf life study and clinical study of the product.


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