scholarly journals OP03.03: Factors influencing transplacental transmission of IgG antibodies providing newborns with maternal passive immunity after COVID‐19 in pregnancy

2021 ◽  
Vol 58 (S1) ◽  
pp. 65-66
Author(s):  
A. Tallarek ◽  
B.G. Hollwitz ◽  
M. Lütgehetmann ◽  
P. Arck ◽  
A. Diemert ◽  
...  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Afsaneh Keramat ◽  
Mina Malary ◽  
Mahmood Moosazadeh ◽  
Nastaran Bagherian ◽  
Mohammad-Reza Rajabi-Shakib

Abstract Background Pregnancy is a unique period with the increased likelihood of psychological changes and emotional disturbances such as depression, anxiety, and stress. In this study, we investigated the factors influencing depression, anxiety, and stress in pregnancy and identify their associations with Sexual Distress (SD) and Genital Self-Image (GSI). Methods This was a descriptive, correlational, cross-sectional study performed using the two-stage cluster sampling method between September 2019 and January 2020. Overall, 295 pregnant women completed a demographics and obstetric information checklist, Depression Anxiety and Stress Scale-21 (DASS-21), Female Genital Self-Image Scale (FGSI), and Female Sexual Distress Scale-Revised (FSDS-R). Results Analysis of Variance (ANOVA) showed significant differences in the mean scores of SD between the groups with varying degrees of depression, anxiety, and stress (P <  0.001) and in the mean score of GSI between the groups with varying degrees of depression (P = 0.01) and anxiety (P <  0.001). In multivariate linear regression analysis, higher (worse) depression, anxiety, and stress scores were found in women with more advanced age and higher SD scores; however, these scores were lower (better) in those with increased gestational age. Lower depression and anxiety scores were associated with moderate satisfaction with income, moderate satisfaction with BI in pregnancy, and lower stress and depression scores were linked to planned pregnancy. Higher (better) GSI score was a predictor of lower depression score, complication in a previous pregnancy was a predictor of higher stress score, and finally, fear of fetal abortion and being a housewife were predictors of a higher anxiety score. Conclusion Various factors contribute to the development of antenatal depression, anxiety, and stress. A positive correlation was found between SD and the severity of depression, anxiety, and stress, while a negative correlation was noted between GSI and the severity of depression and anxiety. Therefore, raising awareness regarding SD and GSI through screening and counseling sessions can have beneficial effects for mothers and their fetuses.


2011 ◽  
Vol 140 (9) ◽  
pp. 1599-1606 ◽  
Author(s):  
E. BORRÀS ◽  
L. URBIZTONDO ◽  
J. COSTA ◽  
J. BATALLA ◽  
N. TORNER ◽  
...  

SUMMARYPassive immunity against measles decreases during the first months of life. The objective of this study was to determine titres of measles antibodies in children aged 9–14 months and their mothers before vaccination, and the children's response to vaccination. Blood samples were collected by capillary puncture before and 28 days after vaccination. Samples were obtained between February and June 2007 during an ongoing measles outbreak. Titres of specific measles IgG antibodies were determined by enzyme-linked immunosorbent assay. Seroconversion was defined as the presence of antibodies after vaccination in subjects without antibodies before vaccination. Maternal antibodies were present in 37·7% of all 69 children included and in 45·1% of children aged 9 months. Of the 51 children in whom a second sample was obtained, 31 (60·8%) were seronegative before vaccination and 61·3% seroconverted. Interference of maternal antibodies was 30%. Advancing the first dose of measles vaccination from 15 to 12 months is a correct strategy, given the increase in the time of susceptibility of infants to measles.


2022 ◽  
Vol 10 (1) ◽  
pp. 176
Author(s):  
Irina Anatolyevna Andrievskaya ◽  
Irina Valentinovna Zhukovets ◽  
Inna Victorovna Dovzhikova ◽  
Nataliya Alexandrovna Ishutina ◽  
Ksenia Konstantinovna Petrova

The goal of this research was to evaluate seropositivity to HSV-1 among pregnant women and its effect on the course of pregnancy, childbirth and the condition of newborns. Methods: The serological status, socio-demographic characteristics, parity of pregnancy and childbirth and condition of newborns in women seronegative and seropositive to HSV-1 with recurrent infection and its latent course during pregnancy were analyzed. Newborns from these mothers made up the corresponding groups. Results: Low titers of IgG antibodies to HSV-1 in women in the first trimester of pregnancy are associated with threatened miscarriage, anemia in pregnancy and chronic placental insufficiency. High titers of IgG antibodies to HSV-1 in women in the second trimester of pregnancy are associated with late miscarriages and premature births, anemia in pregnancy, chronic placental insufficiency, labor anomalies, early neonatal complications (cerebral ischemia, respiratory distress syndrome) and localized skin rashes. Low titers of IgG antibodies to HSV-1 in women in the third trimester of pregnancy are associated with premature birth, anemia in pregnancy, chronic placental insufficiency, endometritis, complications of the early neonatal period and localized skin rashes. Conclusions: Our research showed that low or high titers of IgG antibodies to HSV-1, determined by the timing of recurrence of infection during pregnancy, are associated with a high incidence of somatic pathology and complications in pregnancy, childbirth and the neonatal period.


BMJ Open ◽  
2016 ◽  
Vol 6 (4) ◽  
pp. e010790 ◽  
Author(s):  
Fiona McQuaid ◽  
Christine Jones ◽  
Zoe Stevens ◽  
Jane Plumb ◽  
Rhona Hughes ◽  
...  

Pain ◽  
2019 ◽  
pp. 989-992
Author(s):  
Rany Abdallah ◽  
Petrus Paulus Steyn ◽  
Ihab Kamel

Endocrinology ◽  
1973 ◽  
Vol 93 (2) ◽  
pp. 423-429 ◽  
Author(s):  
MEMMA D. COVELLI ◽  
D.A. DENTON ◽  
J.F. NELSON ◽  
A.A. SHULKES

2015 ◽  
Vol 125 (2) ◽  
pp. 87-89
Author(s):  
Dorota Robak-Chołubek ◽  
Gustaw Chołubek ◽  
Ewa Piróg

Abstract Introduction. Pregnant women often create their own image of a child. The ultrasound is able to model and modify this picture. The image of the unborn child develops along with the process of creating the space for the baby on the psychological and emotional level and is continued after the delivery. Aim. The authors of the study made an attempt to evaluate the influence of fetal sex determination during ultrasound in pregnancy on emotional and ‘practical’ experiencing late pregnancy - after the 28th week of its duration. Material and methods. The study included 200 pregnant women. Qualification criteria for the research was the declared awareness of fetal sex confirmed by ultrasound. Among others, factors influencing decision to determine fetal sex, emotional bond with the unborn child after identifying the sex, as well as preparation for birth regarding prognosticated sex were assessed. Results. Nearly all pregnant women wanted to find out the fetal sex, usually claiming that they did so out of curiosity. After they did it, about 2/3 of them stated that the emotional bond with the baby increased and the vast majority of women started preparing layettes for their future babies. Conclusions. Determination of fetal sex during ultrasound improves the relationship between the mother and her future baby. It also enables the woman to prepare for childbirth considering its sex by the purchase of clothes, pram and preparation of layette or baby’s room


1952 ◽  
Vol 84 (5) ◽  
pp. 131-139 ◽  
Author(s):  
W. F. Baldwin ◽  
H. L. House

The physiochemical properties of the blood of an animal are maintained in a close equilibrium conducive to the normal functioning of the organism. Disturbances in the physiological functian may result in characteristic changes in the blood. For example, the specific gravity of normal human blood, which averages about 1.060, may vary with age, sex, nutritive condition, and disease (Hawk, Oser. and Summerson, 1947). The reaction of blood to metabolic and pathological conditions is recognized by the medical profession as a valuable aid in diagnosis (Scudder, 1939). Changes have been shown in the specific gravity of human blood in pregnancy and cancer (Polowe, 1932; 1934). It has also been shown that haemorrhage is accompanied by a decline in the specific gravity (Richet, Brodin, and Saint-Girons, 19 18).


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