Background and Objective:
In this study, dudoa (Hydnocarpus alcalae C.DC.) leaf extract
was used as a reducing and stabilizing agent in a novel one-step green synthesis of silver nanoparticles.
Dudoa is an endemic plant in the province of Legazpi, Philippines and its seed oil was used as an
anti-leprotic drug.
Method:
Therefore, the dudoa leaf extract was used to synthesize silver nanoparticles. Moreover, optimization
of various parameters greatly affected the size and morphology of the synthesized AgNPs
as indicated by the Ultraviolet-visible (UV-vis) spectrophotometry. The synthesized AgNPs were further
characterized using spectral analyses such as XRD, EDX, SEM, FT-IR, TGA and DLS. The antimicrobial
activity of synthesized AgNPs was also demonstrated.
Results and Discussions:
The synthesized AgNPs exhibited a diffraction pattern and a particle size
ranging from 22-48 nm. The AgNPs also showed complete inhibitory and mild reactivity against representative
pathogenic gram-positive (S.aureus) and gram-negative (E.coli) bacteria.
Conclusion:
Silver nanoparticles were successfully synthesized using H. alcalae leaf extract. Furthermore,
this green synthesis approach appeared to be cost-effective, non-toxic, and eco-friendly
which is a best alternative to the conventional chemical methods.
Evaluating the antimicrobial activity and antitumor screening of green synthesized silver nanoparticles compounds, using Syzygium jambolanum, towards MCF7 cell line (Breast cancer cell line)