China and the United States are the two largest economies in the world, and there is a strong complementarily between their economies, so the volume of their bilateral trade is also very large. However, with the development of trade exchanges, bilateral trade friction also intensifies; especially in recent years, American trade deficit with China has grown very rapidly. In order to reverse the situation, the United States launched several trade litigations and implemented tough trade sanctions against China. It led to trade disputes between the two countries, which seriously damaged the healthy development of Sino-US relation. So we compares the similarities and differences between the two trade frictions, pointing out both valuable experience and negative lessons from Japan in handling Japan-US trade friction, so as to provide reference to China for easing Sino-US trade friction.