Comparison of the biological activity of fusicoccin in higher plants with its binding to plasma membranes

Planta ◽  
1991 ◽  
Vol 183 (3) ◽  
Author(s):  
N.Yu. Abramycheva ◽  
A.V. Babakov ◽  
S.V. Bilushi ◽  
E.E. Danilina ◽  
V.P. Shevchenko
Keyword(s):  
Biological Activity ◽  
Plasma Membranes ◽  
Higher Plants

The biological activity of glucagon–phospholipid complexes

1983 ◽  
Vol 61 (7) ◽  
pp. 688-691 ◽  
Author(s):  
J. J. Liepnieks ◽  
P. Stoskopf ◽  
E. A. Carrey ◽  
C. Prosser ◽  
R. M. Epand
Keyword(s):  
Biological Activity ◽  
Adenylate Cyclase ◽  
Plasma Membranes ◽  
Bovine Brain ◽  
Water Soluble ◽  
Dipalmitoyl Phosphatidylcholine ◽  
Dimyristoyl Phosphatidylcholine ◽  
Lipoprotein Complex ◽  
Stimulation Of

Glucagon can form water-soluble complexes with phospholipids. The incorporation of glucagon into these lipoprotein particles reduces the biological activity of the hormone. The effect is observed only at temperatures below the phase transition temperature of the phospholipid and results in a decreased stimulation of the adenylate cyclase of rat liver plasma membranes by the lipoprotein complex as compared with the hormone in free solution. Two- to five-fold higher concentrations of glucagon are required for half-maximal stimulation of adenylate cyclase when the hormone is complexed with dimyristoyl phosphatidylcholine, dipalmitoyl phosphatidylcholine, or bovine brain sphingomyelin. A possible role of lipoprotein-associated hormones in the development of insulin resistance is discussed.

Sugar transport across the plasma membranes of higher plants

1994 ◽  
Vol 26 (5) ◽  
pp. 1671-1679 ◽  
Author(s):  
Norbert Sauer ◽  
Kerstin Baier ◽  
Manfred Gahrtz ◽  
Ruth Stadler ◽  
J�rgen Stolz ◽  
...  
Keyword(s):  
Plasma Membranes ◽  
Higher Plants ◽  
Sugar Transport

Biosynthesis and biological activity of β-(5-methylisoxazolin-3-on-2-yl)alanine in higher plants

1985 ◽  
Vol 24 (8) ◽  
pp. 1693-1695 ◽  
Author(s):  
Isamu Murakoshi ◽  
Fumio Ikegami ◽  
Tadahiro Nishimura ◽  
Kazuo Tomita
Keyword(s):  
Biological Activity ◽  
Higher Plants

scholarly journals Sesquiterpene lactones – occurrence and biological properties. A review

2018 ◽  
Vol 73 (3) ◽  
pp. 83-95
Author(s):  
KATARZYNA OLESIŃSKA
Keyword(s):  
Biological Activity ◽  
Secondary Metabolites ◽  
Plant Pathogens ◽  
Higher Plants ◽  
Sesquiterpene Lactones ◽  
Biological Properties ◽  
Chemical Structures ◽  
Potential Source ◽  
Active Substances ◽  
Carbon Pathways

Sesquiterpene lactones are secondary metabolites commonly found in higher plants as well as mosses, lichens, and fungi. Currently, over 5000 of such compounds have been identified with a majority isolated from Asteraceae plants. They are characterised by different chemical structures associated with the presence of various carbon pathways and functional groups, which exert an impact on their pharmacological activity. These colourless substances are soluble in fats, alcohols, or water. They are often bitter ingredients regarded as bitter compounds. They are accumulated mainly in leaves, flower parts and seeds; less frequently, they are present in roots. Sesquiterpene lactones exhibit multidirectional biological activity: some of them have anticancer, anti-inflammatory, antidiabetic, analgesic, antiparasitic, antifungal, and bacteriostatic effects. Therefore, high hopes are placed on the medical and pharmaceutical use of these substances. Lactone compounds are also regarded as a potential source of new active substances used in agriculture to combat plant pathogens

Sugar transport across the plasma membranes of higher plants

1994 ◽  
pp. 435-443
Author(s):  
Norbert Sauer ◽  
Kerstin Baier ◽  
Manfred Gahrtz ◽  
Ruth Stadler ◽  
Jürgen Stolz ◽  
...  
Keyword(s):  
Plasma Membranes ◽  
Higher Plants ◽  
Sugar Transport

Chemical composition and biological activity of sapropel in the Orenburg region (V. Sol-Iletsk), genetic link with the composition of the sapropel formers

10.12737/5040 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-8
Author(s):  
Фридзон ◽  
K. Fridzon ◽  
Платонов ◽  
V. Platonov ◽  
Хадарцев ◽  
...  
Keyword(s):  
Organic Matter ◽  
Biological Activity ◽  
Comparative Analysis ◽  
Chemical Composition ◽  
Chemical Compound ◽  
Higher Plants ◽  
Biological Testing ◽  
Genetic Link ◽  
Orenburg Region ◽  
Animal Material

The features of chemical composition of sapropel in district Sol-Iletsk (Orenburg region) were studied in detail. Biological testing of sapropel preparations was carried out. Comparative analysis of the chemical composition of sapropel and flora, fauna, meadow, higher plants, algae with a composition of organic matter sapropel was made. Genetic link of chemical compound of sapropel, plant and animal material, participating in the formation of the latter, with biological activity sapropel drugs was established.

scholarly journals ANALYSIS OF FLAVONES C-GLYCOSIDES AND AND STEPWISE HYDROLYSIS OF THEIR ACETATES IN THE LEAVES OF RUBUS CHAMAEMORUS L.

2021 ◽  
pp. 257-265
Author(s):  
Andrey Kennet Whaley ◽  
Anastasiya Olegovna Ponkratova ◽  
Anastasiya Andreyevna Orlova ◽  
Evgeni Borisovich Serebryakov ◽  
Stanislav Ivanovich Selivanov ◽  
...  
Keyword(s):  
Biological Activity ◽  
Hplc Analysis ◽  
Higher Plants ◽  
Two Dimensional ◽  
Cardiotonic Activity ◽  
Hydrolysis Products ◽  
Rubus Chamaemorus ◽  
Growing Conditions ◽  
First Time ◽  
Hydrolysis Of

The C-glycoside embinin and its mono- and diacetate derivatives have immunotropic and cardiotonic activity, which makes the search for plants that contain them interesting. Embinin and its acetate derivatives were previously isolated only from some plants of the genus Iris, the habitat and growing conditions of which are very different from those of the genus Rubus. As a result of the study, the structure of seven C-glycosides, embinin derivatives, isolated from the leaves of Rubus chamaemorus L. (Rosaceae) was established. Using HR-ESI-MS, HPLC-MS, as well as one- and two-dimensional NMR spectroscopy, the structure of three substances isolated in individual form was established: embinin (1) and its diacetyl derivatives – 2''',3'''-diacetylembinin (5) and 3''',4'''-diacetylembinin (7). The method of stepwise hydrolysis of C-glycoside acetate residues proposed in this study, followed by HPLC analysis of the resulting hydrolysis products, made it possible to establish the structure of minor flavone C-glycosides contained in the leaves of Rubus chamaemorus L.: 2'''-acetylembinin (2), 3'''-acetylembinin (3), 4'''-acetylembinin (4) and 2''',4'''-diacetylembinin (6). All these compounds were found in the leaves of Rubus chamaemorus L. for the first time. The C-glycosides - embinin and its acetate derivatives are rare metabolites of higher plants, the presence of which is determined by the peculiarity of their physiology, and the biological activity determines the prospects for medical use.

scholarly journals A membrane-anchored E-type endo-1,4- -glucanase is localized on Golgi and plasma membranes of higher plants

1997 ◽  
Vol 94 (9) ◽  
pp. 4794-4799 ◽  
Author(s):  
D. A. Brummell ◽  
C. Catala ◽  
C. C. Lashbrook ◽  
A. B. Bennett
Keyword(s):  
Plasma Membranes ◽  
Higher Plants

scholarly journals The liver angiotensin receptor involved in the activation of glycogen phosphorylase

1982 ◽  
Vol 208 (3) ◽  
pp. 809-817 ◽  
Author(s):  
Stefaan Keppens ◽  
Henri De Wulf ◽  
Pascale Clauser ◽  
Serge Jard ◽  
Jean-Louis Morgat
Keyword(s):  
Biological Activity ◽  
Rate Constant ◽  
Glycogen Phosphorylase ◽  
Plasma Membranes ◽  
Binding Capacity ◽  
Rat Hepatocytes ◽  
Dissociation Rate ◽  
Biologically Active ◽  
Maximal Binding ◽  
Highly Correlated

Specific angiotensin binding to rat hepatocytes and purified liver plasma membranes was measured by using biologically active [3H]angiotensin (sp. radioactivity 14Ci/mmol). The kinetic parameters for angiotensin binding to hepatocytes are: K+1 (association rate constant). 100μm−1·min−1; K–1 (dissociation rate constant), 2min−1; Kd (dissociation constant). 30nm; maximal binding capacity, 0.42pmol/106 cells or 260000 sites/cell. Angiotensin binding to membranes is profoundly affected by GTP (0.1mm) and NaCl (100mm); these regulatory compounds greatly enhance both the rate of association and of dissociation and also the extent of dissociation. Kd amounts to 10nm in the presence of GTP+NaCl and to 1.5nm in their absence; maximal binding capacity is 0.70pmol/mg of protein, both with or without GTP+NaCl. The relative affinities of 11 angiotensin structural analogues were deduced from competition experiments for [3H]angiotensin binding to hepatocytes and to membranes (in the latter case, GTP + NaCl were not included, in order to study the higher affinity state of the receptor). These are highly correlated with their biological activity (activation of glycogen phosphorylase in hepatocytes). Binding to membranes occurs in the same concentration range as the biological effect. On the other hand, the existence of numerous spare receptors is suggested by the observation that binding of the agonists to hepatocytes requires 25-fold higher concentrations than those needed for their biological activity. These data clearly suggest that the detected binding sites correspond to the physiological receptors involved in the glycogenolytic action of angiotensin on rat liver.

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