Environmental factors, medical and family history, and comorbidities associated with primary biliary cholangitis in Japan: a multicenter case–control study

2021 ◽  
Author(s):  
Kosuke Matsumoto ◽  
Satoko Ohfuji ◽  
Masanori Abe ◽  
Atsumasa Komori ◽  
Atsushi Takahashi ◽  
...  
Keyword(s):  
Family History ◽  
Environmental Factors ◽  
Case Control Study ◽  
Case Control ◽  
Primary Biliary Cholangitis ◽  
Control Study

scholarly journals The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Meng Wang ◽  
Wei-Wei Gong ◽  
Feng Lu ◽  
Ru-Ying Hu ◽  
Qing-Fang He ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Family History ◽  
Case Control Study ◽  
Positive Family History ◽  
Case Control ◽  
Diabetes Duration ◽  
Family History Of Diabetes ◽  
Thyroid Cancer Risk ◽  
History Of ◽  
Control Study

Abstract Background Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population. Methods A 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined. Results Overall, neither diabetes (OR = 0.75, 95 % CI: 0.21–2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02–1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32–13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes. Conclusions Diabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.

scholarly journals Lifestyle, Family History, and Risk of Idiopathic Parkinson Disease: A Large Danish Case-Control Study

2015 ◽  
Vol 181 (10) ◽  
pp. 808-816 ◽  
Author(s):  
Line Kenborg ◽  
Christina F. Lassen ◽  
Beate Ritz ◽  
Klaus K. Andersen ◽  
Jane Christensen ◽  
...  
Keyword(s):  
Family History ◽  
Parkinson Disease ◽  
Case Control Study ◽  
Case Control ◽  
Idiopathic Parkinson Disease ◽  
Control Study

scholarly journals Environmental Factors and the Risk of Type 1 Diabetes Mellitus-A Case-Control Study

2017 ◽  
Vol 08 (02) ◽  
Author(s):  
Basma Abdelmoez Ali ◽  
Mostafa Ahmed Elfoly ◽  
Eman Ramadan Ghazawy ◽  
Rania Rashad Bersom
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Environmental Factors ◽  
Type 1 Diabetes Mellitus ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Environmental factors in infancy and ulcerative colitis in the Central South of Chile: A case–control study

2011 ◽  
Vol 5 (5) ◽  
pp. 392-396 ◽  
Author(s):  
Anja Boneberger ◽  
Eduardo Hebel Weiss ◽  
Mario Calvo ◽  
Lilibeth Torres ◽  
Johanna Wagner ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Environmental Factors ◽  
Case Control Study ◽  
Case Control ◽  
Central South ◽  
Control Study

scholarly journals Family history of hypertension increases risk of preeclampsia in pregnant women: a case-control study

2016 ◽  
Vol 35 (3) ◽  
pp. 181 ◽  
Author(s):  
Mulualem Endeshaw ◽  
Fantu Abebe ◽  
Melkamu Bedimo ◽  
Anemaw Asrat ◽  
Abebaw Gebeyehu ◽  
...  
Keyword(s):  
Family History ◽  
Pregnant Women ◽  
Case Control Study ◽  
Multiple Logistic Regression Analysis ◽  
Multiple Pregnancy ◽  
Case Control ◽  
Outcome Variable ◽  
History Of ◽  
Family History Of Hypertension ◽  
Control Study

Background <br />Preeclampsia is one of the leading causes of maternal and fetal morbidity and mortalities worldwide. Despite extensive research, the underlying cause of preeclampsia remains poorly understood. This study aimed to offer compelling evidence on the important risk factors of preeclampsia in Amhara region, Ethiopia.<br /><br />Methods<br />A case control study was conducted in public health facilities of Bahir Dar city from September 2014 to January 2015. A total of 453 (151 cases and 302 controls) pregnant women were enrolled in this study. Hemoglobin level and urinary tract infection (UTI) status were collected from clinical notes. Oral examination was performed by a dentist for detection of periodontal diseases. Univariate and multiple logistic regression analysis was conducted to determine the relationship of all the independent variables with the outcome variable. A p-value &lt;0.05 was declared statistically significant.<br /><br />Result<br />Advanced maternal age (AOR=4.79;95% CI 1.031-22.18), family history of hypertension (AOR=11.16;95% CI 5.41-41.43), history of diabetes mellitus (AOR=6.17;95% CI 2.11-20.33), UTI in the current pregnancy (AOR=6.58;95% CI 2.93-14.73), failure to comply with iron and folic acid supplement during pregnancy (AOR=8.32;95% CI 3.35-20.62), lack of exercise (AOR=3.33;95% CI 1.35-8.17), multiple pregnancy (AOR=4.05;95% CI 1.57-12.27), anemia (AOR=4.19;95% CI 1.27-13.92), and periodontal disease or gingivitis (AOR =3.51;95% CI 1.14-10.83) were associated with preeclampsia.<br /><br />Conclusion <br />Family history of hypertension was the most dominant risk factor for preeclampsia in pregnant women. Encouraging pregnant women to have health seeking behavior during pregnancy would provide a chance to diagnose preeclampsia as early as possible.

scholarly journals The Relationship of Residential Environment with The Risk of Leptospirosis in Sleman Regency

2017 ◽  
Vol 1 (2) ◽  
pp. 85-92
Author(s):  
Maya Sofiyani ◽  
M Imron Mawardi ◽  
P Sigit Purnomo ◽  
Hariza Adnani
Keyword(s):  
Environmental Factors ◽  
Case Control Study ◽  
Case Control ◽  
Survey Method ◽  
Control Programs ◽  
The Government ◽  
Relationship Of ◽  
The Relationship ◽  
Control Study ◽  
Made In

The effort of leptospirosis prevention in Sleman currently only limited to counseling and treatment of the patient, while the patient search, ways of transmission of leptospirosis from rats to humans, have never implemented in an integrated manner. The study aimed to investigated the relationship between the environmental residential condition with the risk of leptospirosis in Sleman Regency. The research used a survey method  with case control study design. The results showed that environmental factors, which are not proved to have a relationship with the risk of leptospirosis were residential condition ({p=0,108} OR=3,818 {95%CI:0,922–15,811}), the trash bin condition ({p=1,000} OR=1,138 {95%CI:0,420–3,081}) and the sewer condition ({p=0,415} OR=0,551 {95%CI:0,187–1,624}). Environmental factors that associated with the risk of leptospirosis was the presence of rats ({p=0,001} OR=13,594 {95%CI:2,754–67,107}). The effort should be made in order to prevent the increasement of Leptospirosis cases by sanitation improvement and avoiding direct contact with rats as well as it litter. The Government should be pay more attention in the vector control programs, especially in leptospirosis prone areas so the prevention effort to be able run effectively and efficiently.

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