scholarly journals Work absenteeism and disability associated with psoriasis and psoriatic arthritis in the USA—a retrospective study of claims data from 2009 TO 2020

2021 ◽  
Author(s):  
A. M. Orbai ◽  
S. M. Reddy ◽  
N. Dennis ◽  
R. Villacorta ◽  
S. Peterson ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Claims Data ◽  
Control Group ◽  
Work Absence ◽  
Short Term ◽  
Work Absenteeism ◽  
Key Points ◽  
The Usa ◽  
And Control ◽  
Substantial Economic Burden

Abstract Objectives To compare work absenteeism and short-term disability among adults with psoriasis or psoriatic arthritis (PsA), versus controls in the USA. Methods Adults eligible for work absenteeism and/or short-term disability benefits between 1/1/2009 and 4/30/2020 were screened in the IBM® MarketScan® Commercial and Health and Productivity Management Databases. The following groups were defined: (1) psoriasis: ≥ 2 psoriasis diagnoses ≥ 30 days apart and no PsA diagnoses; (2) PsA: ≥ 2 PsA diagnoses ≥ 30 days apart; (3) control: absence of psoriasis and PsA diagnoses. Controls were matched to psoriasis and PsA patients based on age, gender, index year, and comorbidities. Non-recreational work absences and sick leaves were evaluated in absentee-eligible patients, and short-term disability was evaluated in short-term disability-eligible patients. Costs (in 2019 USD) associated with each type of work absence were evaluated. Results 4261 psoriasis and 616 PsA absentee-eligible and 25,213 psoriasis and 3480 PsA short-term disability-eligible patients were matched to controls. Average non-recreational work absence costs were $1681, $1657, and $1217 for the PsA, psoriasis, and control group, respectively. Compared with psoriasis patients and controls, more PsA patients had sick leaves after 1 year (56.2% versus 55.6% and 41.5%, p < 0.0001). Similarly, short-term disability was more frequent in PsA patients than psoriasis patients and controls at year one (8.8% versus 5.6% and 4.7%, p < 0.0001) and corresponding costs were higher ($605, $406, and $335 on average, p < 0.0001). Conclusion Annual work absenteeism and short-term disability were consistently greater among patients with PsA and psoriasis than controls, highlighting the substantial economic burden of psoriatic disease. Key points• Patients with PsA had greater short-term disability compared with patients with psoriasis and patients with neither psoriasis nor PsA.• Patients with PsA and patients with psoriasis incurred greater non-recreational work absences and sick leaves than patients with neither psoriasis nor PsA.

scholarly journals Effect of Carnatic Music Listening Training on Speech in Noise Performance in Adults

2021 ◽  
Vol 25 (1) ◽  
pp. 22-26
Author(s):  
Raksha Amemane ◽  
Archana Gundmi ◽  
Kishan Madikeri Mohan
Keyword(s):  
Repeated Measures ◽  
Functional Organization ◽  
Control Group ◽  
Music Listening ◽  
Noise Performance ◽  
Short Term ◽  
Speech In Noise ◽  
Carnatic Music ◽  
Significant Difference ◽  
And Control

Background and Objectives: Music listening has a concomitant effect on structural and functional organization of the brain. It helps in relaxation, mind training and neural strengthening. In relation to it, the present study was aimed to find the effect of Carnatic music listening training (MLT) on speech in noise performance in adults.Subjects and Methods: A total of 28 participants (40-70 years) were recruited in the study. Based on randomized control trial, they were divided into intervention and control group. Intervention group underwent a short-term MLT. Quick Speech-in-Noise in Kannada was used as an outcome measure.Results: Results were analysed using mixed method analysis of variance (ANOVA) and repeated measures ANOVA. There was a significant difference between intervention and control group post MLT. The results of the second continuum revealed no statistically significant difference between post training and follow-up scores in both the groups.Conclusions: In conclusion short-term MLT resulted in betterment of speech in noise performance. MLT can be hence used as a viable tool in formal auditory training for better prognosis.

Abstract 16237: Zero Fluoroscopy Ablation of Atrial Fibrillation: A Safety and Feasibility Study

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Luigi Di Biase ◽  
Rodney Horton ◽  
Chintan Trivedi ◽  
Prasant Mohanty ◽  
Sanghamitra Mohanty ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Pulmonary Veins ◽  
Radiation Risk ◽  
Control Group ◽  
Short Term ◽  
Af Ablation ◽  
And Control ◽  
Zero Fluoroscopy

Introduction: Radiofrequency catheter ablation of atrial fibrillation is performed under fluoroscopic guidance and therefore carries radiation risk exposure for the both the patient and the operator. Three-dimensional mapping systems and newer technologies to allow non-fluoroscopic catheter visualization together with intracardiac echo have reduced but not abolished the fluoroscopy exposure. We aim to demonstrate the feasibility, the safety and the efficacy of catheter ablation for atrial fibrillation without the use of fluoroscopy. Methods: A totally fluoro-less approach was developed for AF ablation at our Institution. 94 consecutive AF patients underwent zero fluoroscopy catheter ablation for atrial fibrillation. In the zero fluoroscopy cases, the fluoroscopy arm was kept far away from the patient table. Access including double trans-septal, mapping with the Carto 3 system and ablation were all performed without fluoroscopy with the use of ICE and the Carto 3 system. These 94 patients were compared with 94 control patients matched for age, sex and type of AF who underwent AF ablation by the same operator with the use of fluoroscopy. Results: Baseline characteristics were similar between fluoroless (N=94, Age=64.5 ± 10.1, 75.5% male, 48% paroxysmal) and control (N=94, Age=65.1 ± 9.9, 72.3% male, 50% paroxysmal) group. Non-PV triggers were detected and ablated in 51 (54.3%) and 56 (59.6%) patients in fluoroless and control group respectively (p=0.5). Average fluoro time in control group was 10.1 ± 4.7 minutes. Procedure duration was comparable (120.4 ± 25.8 vs. 122.2 ± 28.7, p =0.6). After the short term median follow-up of 4.5 (4 – 6.5) months, 10 (10.6 %) patients in flourless and 9 (9.6%) patients in control group experienced recurrences (p=0.8).One pericardial effusion requiring pericardiocenteis occurred in the fluoroless group. Conclusions: Our series show that zero fluoroscopy ablation of atrial fibrillation with the use of newer technologies is feasible, safe and efficacious at the short term follow up. Importantly in our series the double transeptal was performed without fluoroscopy and the ablation was not limited to the pulmonary veins only but included ablation of the posterior wall, the coronary sinus and the left atrial appendage.

A Comparative Study on Short-Term Effects of Compression Orthosis and Exercises in the Treatment of Pectus Carinatum: A Randomized Controlled Pilot Feasibility Trial

2020 ◽  
Author(s):  
Esra Giray ◽  
Nezih Onur Ermerak ◽  
Yeliz Bahar-Ozdemir ◽  
Melihat Kalkandelen ◽  
Mustafa Yuksel ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Chest Wall ◽  
Feasibility Trial ◽  
Control Group ◽  
Pectus Carinatum ◽  
Short Term ◽  
Similar Frequency ◽  
Custom Made ◽  
Before And After ◽  
And Control

Abstract Introduction Pectus carinatum (PC) is a congenital chest wall deformity which is characterized by the protrusion of the sternum and costal cartilages. Although orthotic and exercise therapies are commonly offered by physicians for PC treatment, there is a lack of evidence on the benefits of exercises and how long the orthosis should be worn. The aim of this study is to investigate the effects and feasibility of custom-made compression orthosis and exercises in the treatment of PC. Materials and Methods Patients with PC aged 7 to 17 years old were randomized into three groups: compression orthosis 23 hours, compression orthosis 8 hours, and control group. All groups received exercises for 1 hour a day for 3 weeks. Additionally, compression orthosis 23 hours group wore the orthosis for 23 hours a day, while compression orthosis 8 hours group wore the orthosis for 8 hours a day. PC protrusion, pressure of correction, thorax lateral and anteroposterior parameters, external chest wall measurements, and Nuss Questionnaire were evaluated before and after the treatment. Also, adverse effects, retention, and compliance were assessed. Feasibility was evaluated by calculating the percentages of recruitment, retention, and safety. Results The compression orthosis 23 hours group showed greater improvements than the other groups. After treatment, all groups showed significant changes in protrusion, pressure of correction, and external chest wall measurements. Adverse events occurred with similar frequency across groups. Retention percentages did not differ among groups. Conclusion Compression orthosis use for 23 hours can be recommended rather than its use for 8 hours because 23 hours of orthosis use has better correction and similar adverse effects.

scholarly journals Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Hongyan Chen ◽  
Jianping Dai ◽  
Xiaozhe Zhang ◽  
Kai Wang ◽  
Shuhua Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular System ◽  
Acupuncture Treatment ◽  
Bodily Pain ◽  
Brain Network ◽  
Control Group ◽  
Control Groups ◽  
Short Term ◽  
Sf 36 ◽  
And Control

The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. The acupuncture group received a continuous five-day acupuncture treatment and undertook three resting-state fMRI scans and 24-hour ambulatory blood pressure monitoring (ABPM) as well as SF-36 questionnaires before, after, and one month after acupuncture treatment. The control group undertook fMRI scans and 24-hour ABPM. For verum acupuncture, average blood pressure (BP) and heart rate (HR) decreased after treatment but showed no statistical differences. There were no significant differences in BP and HR between the acupuncture and control groups. Notably, SF-36 indicated that bodily pain (P= 0.005) decreased and vitality (P= 0.036) increased after acupuncture compared to the baseline. The hypothalamus-related brain network showed increased functional connectivity with the medulla, brainstem, cerebellum, limbic system, thalamus, and frontal lobes. In conclusion, short-term acupuncture did not decrease BP significantly but appeared to improve body pain and vitality. Acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem.

scholarly journals The short – term nephropathological complications due to alloxan induction of diabetes mellitus in male rabbits

2012 ◽  
Vol 11 (1) ◽  
pp. 47
Author(s):  
H. Kh. U. Al-Karagoly And K. F. AbdulKareem
Keyword(s):  
Diabetes Mellitus ◽  
Control Group ◽  
Glomerular Hypertrophy ◽  
Pathological Changes ◽  
Fasting Serum ◽  
Short Term ◽  
Short Period ◽  
Alloxan Monohydrate ◽  
Histopathological Results ◽  
And Control

This study was conducted to assess the pathological changes in kidneys after twenty day from induction of diabetes mellitus in male rabbits.Sixteen male rabbits were used in this study and divided into two equal groups: diabetic group (Dm) and control group (Cm). Diabetes mellitus was induced by i.v injection of alloxan monohydrate at dose rate 100 mg/kg dissolved in 1 ml of normal saline. Blood was collected after three days to check fasting serum glucose.Serum glucose level was elevated starting from the 1st 3 days after induction of diabetes mellitus. The histopathological results revealed that there were: edema, glomerular hypertrophy and hypercellularity, as well as glomerular necrosis, glomerular swelling, glomerular congestion with glomerular cast and rupture. The conclusion that renal glomeruli and tubules affected progressively after short period from beginning of diabetes mellitus.

scholarly journals Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against ear mite (Otodectes cynotis) infestations in cats

Parasite ◽  
2021 ◽  
Vol 28 ◽  
pp. 26 ◽  
Author(s):  
Eric Tielemans ◽  
Joe Prullage ◽  
Otsuki Tomoko ◽  
Julian Liebenberg ◽  
Balázs Capári ◽  
...  
Keyword(s):  
Field Trial ◽  
Treated Group ◽  
Control Group ◽  
Laboratory Studies ◽  
Topical Formulation ◽  
Label Dose ◽  
The Usa ◽  
Ear Canals ◽  
And Control ◽  
Otodectes Cynotis

Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel, nematodicidal and cestodicidal compounds, in NexGard® Combo, a novel topical endectoparasiticide formulation for cats. The efficacy of this formulation was assessed against Otodectes cynotis in two laboratory studies conducted in South Africa and in the USA with local isolates, and in one field trial conducted in Europe. In each study, cats were randomly allocated to a placebo-treated control group and a novel formulation-treated group. In the laboratory studies, cats were treated at the minimum recommended dose; in the field trial, cats were treated at label dose. All included cats were diagnosed positive for O. cynotis prior to treatment by otoscopy. The main variable of efficacy was a comparison of the number of live O. cynotis collected in both ear canals of all cats in the treated and control groups, one month after treatment. Efficacy of the novel topical formulation exceeded 97% in the three studies. These studies demonstrated the high effectiveness of NexGard® Combo in cats for the treatment of O. cynotis infestations. No health abnormalities were attributed to the treatment in any of the studies.

Abstract 77: Effects Of Short-term Fasting On Mortality, Inflammatory And Coagulation Responses To Endotoxin-induced Shock In Rats

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Kyoko Kobayashi ◽  
Takumi Taniguchi ◽  
Ken Yamamoto
Keyword(s):  
Mortality Rate ◽  
Blood Gases ◽  
Mortality Rates ◽  
Control Group ◽  
Short Term ◽  
Coagulation Parameters ◽  
Arterial Blood ◽  
Sepsis And Septic Shock ◽  
And Control ◽  
Thrombin Antithrombin Iii Complex

Obesity is a common problem in sepsis. We evaluated the effects of short-term fasting on the mortality rate, inflammatory and coagulation response in rats with endotoxin-induced shock. Male Wister rats (n=30) were used. Animals were randomly assigned to one of two groups: control group (n=15), receiving intravenous Escherichia coli endotoxin (15 mg/kg over 2 mins); fasted group (n=15), short-term fasting for 3 days before endotoxin injection. The mortality rates, hemodynamics, arterial blood gases, plasma cytokine concentrations and coagulation parameters were measured. The mortality rates at 8hrs after endotoxin injection were 75% and 7% for control and fasted groups, respectively. Hypotension and the increases of TNF-alpha and interleukin-6 concentrations were less for the fasted group than the control group. Moreover, the increase of the prothrombin-time and thrombin-antithrombin III complex were less for the fasted group than the control group. The present study showed that short-term fasting inhibited hypotension and elevations in cytokine concentrations, reducing the mortality rate of rats with endotoxin-induced shock. Moreover, short-term fasting inhibited the elevation of coagulation parameters. These findings suggest that short-term fasting may exert favorable effects during sepsis and septic shock. Survival curves for fasted and control groups

scholarly journals Effectiveness of combined ultrasound and exercise therapy in the treatment of carpal tunnel syndrome - randomized, placebo-controlled investigation

2018 ◽  
Vol 146 (9-10) ◽  
pp. 561-566
Author(s):  
Milica Lazovic ◽  
Mirjana Kocic ◽  
Marija Hrkovic ◽  
Dejan Nikolic ◽  
Ivana Petronic ◽  
...  
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Pain Intensity ◽  
Carpal Tunnel ◽  
Sensory Nerve ◽  
Ultrasound Treatment ◽  
Control Group ◽  
Short Term ◽  
Sensory Nerve Action ◽  
Tunnel Syndrome ◽  
And Control

Introduction/Objective. The aim of the paper was to evaluate the short-term effectiveness of ultrasound treatment procedure on defined clinical parameters and changes of electrodiagnostic parameters at the median nerve in carpal tunnel syndrome patients. Methods. Thirty-five patients (50 hands) were randomly divided into two groups: the experimental group (EG) (20 patients (29 hands)) and the control group (CG) (15 patients (21 hands)). Twenty sessions of ultrasound treatment were performed over a period of seven weeks and control examination was performed during the eighth week from the initial session. Clinical assessment parameters (pain intensity, superficial sensibility, and Tinel sign), and electrodiagnostic parameters (motor distal latency ? mDL), median sensory nerve conduction velocity (SNCV), and median sensory nerve action potential (SNAP) were assessed both at baseline (T1) and at control (T2). Results. There is significant improvement of pain intensity (T1 ? 10.4/58.6/31; T2 ? 65.5/27.6/6.9; p < 0.001) and superficial sensibility (T1 ? 3.4/69/27.6; T2 ? 44.8/34.5/20.7; p < 0.001) in the EG after the treatment. In the EG, there is significant reduction in frequency of positive Tinel?s sign (T1 ? 100/0; T2 ? 62.1/37.9; p < 0.001), and mDL significantly decreased after the treatment (T1 ? 4.7 ? 1.3; T2 ? 4.5 ? 1.2; p = 0.007), while SNAP (T1 ? 20.2 ? 15.4; T2 ? 24.4 ? 16.5; p < 0.001) and SNCV (T1 ? 36.5 ? 9.8; T2 ? 42.6 ? 9.7; p < 0.001) significantly increased. Conclusion. Ultrasound treatment along with exercises have positive short-term effects and benefits on improvement of clinical and electrodiagnostic findings in individuals with carpal tunnel syndrome.

scholarly journals Cue-Based Feeding and Short-Term Health Outcomes of Premature Infants in Newborn Intensive Care Units(NICU) : A None-Randomized Trial

2021 ◽  
Author(s):  
samane Sefatbaqa ◽  
Yadollah Zahedpasha ◽  
Marzieh Hasanpour ◽  
Karimollah Hajian Tilaki ◽  
Mohammad Reza Zarkesh ◽  
...  
Keyword(s):  
Intensive Care ◽  
Health Outcomes ◽  
Preterm Infants ◽  
Control Group ◽  
Phase Lag ◽  
Control Groups ◽  
Short Term ◽  
The Mean ◽  
Newborn Intensive Care ◽  
And Control

Abstract Background: Feedings based on behavioral cues is a method relying on infants’ behavioral expressions of readiness to feed. The objective of this interventional study was to determine the effect of cue-based feeding on the short-term health outcomes of preterm infants.Methods: This quasi-experimental study utilized a historical or phase lag design. It involved 60 preterm infants admitted to an Iranian referral hospital’s Level III-Newborn Intensive Care Unit (NICU) from June 2018 until January 2019. The experimental group (n=30) received a three-step intervention of offering behavioral-cue-based oral (BCBO) feedings: Step 1 – One BCBO feeding every twelve hours for three days; Step 2 - Two BCBO feedings every 12 hours for three days; and Step 3 – All feedings as BCBO feedings for three days. The control group received standard care feedings. Group difference data were analyzed with SPSS version 16 using descriptive and inferential statistics.Results: The infants’ mean weight at time of discharge for the intervention and control groups were 1492.79 ± 21.65 gr and 1395.71 ± 17.61 gr (P = .003) respectively. The mean durations of achieving full oral feedings in the intervention and control groups were 17 ± 6 and 20 ± 11 days, respectively (P = .19). The mean frequencies of hypoxia were 1 ± 1.54 and 5 ± 9.31 respectively (P = .03) and of gavage feedings 725 ± 584 and 1846 ± 2097 respectively (P = .009). No apnea events were reported for the intervention group; the frequency of apnea in the control group was 1 ± 2.11 (P = .16).Conclusion: The findings indicate that cue-based feeding is beneficial for preterm infants. Therefore, it is recommended that nurses employ cue-based feeding in the NICU.Trial Registration: IRCT20170828035962N2. Registered, 27 /05/ 2018- Prospectively registered, https://www.irct.ir/trial/27024.

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