scholarly journals Survival of an emerging foodborne pathogen: Group B Streptococcus (GBS) serotype III sequence type (ST) 283—under simulated partial cooking and gastric fluid conditions

2018 ◽  
Vol 28 (3) ◽  
pp. 939-944
Author(s):  
Ye Htut Zwe ◽  
Zhu Hui Esther Goh ◽  
Man Ling Chau ◽  
Kyaw Thu Aung ◽  
Hyun-Gyun Yuk
Keyword(s):  
Group B Streptococcus ◽  
Foodborne Pathogen ◽  
Gastric Fluid ◽  
Sequence Type ◽  
Group B

scholarly journals Group B Streptococcus Sequence Type 283 Disease Linked to Consumption of Raw Fish, Singapore

2016 ◽  
Vol 22 (11) ◽  
pp. 1974-1977 ◽  
Author(s):  
Priyanka Rajendram ◽  
Win Mar Kyaw ◽  
Yee Sin Leo ◽  
Hanley Ho ◽  
Wen Kai Chen ◽  
...  
Keyword(s):  
Group B Streptococcus ◽  
Sequence Type ◽  
Raw Fish ◽  
Group B

scholarly journals Xpert GBS Assay for Rapid Detection of Group B Streptococcus in Gastric Fluid Samples from Newborns

2013 ◽  
Vol 52 (2) ◽  
pp. 657-659 ◽  
Author(s):  
C. Jost ◽  
B. Bercot ◽  
H. Jacquier ◽  
L. Raskine ◽  
E. Barranger ◽  
...  
Keyword(s):  
Rapid Detection ◽  
Group B Streptococcus ◽  
Gastric Fluid ◽  
Group B

scholarly journals Whole-Genome Shotgun Sequence of Streptococcus agalactiae Sequence Type 176 Strain 3966RFQB from a Dairy Herd in Selangor, Malaysia

2019 ◽  
Vol 8 (6) ◽  
Author(s):  
A. Bashir ◽  
Z. Zunita ◽  
F. F. A. Jesse ◽  
S. Z. Ramanoon ◽  
M. L. Mohd-Azmi
Keyword(s):  
Streptococcus Agalactiae ◽  
Group B Streptococcus ◽  
Bovine Mastitis ◽  
Dairy Herd ◽  
Sequence Type ◽  
Control Measures ◽  
Content Type ◽  
Whole Genome Shotgun Sequence ◽  
Genome Shotgun Sequence ◽  
Group B

Streptococcus agalactiae, commonly known as group B streptococcus (GBS), is among the most implicated pathogens in bovine mastitis worldwide. Proper control measures can curb both economic and public health effects it may cause.

scholarly journals 125Single Nucleotide Polymorphisms Drive Phenotypic Diversity Among Sequence Type 1 Group B Streptococcus, An Emerging Cause of Invasive Disease in Adult Humans

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S12-S12
Author(s):  
Jessica Galloway-Pena ◽  
Pranoti Sahasrabhojane ◽  
Immaculada Margarit ◽  
Roberto Rosini ◽  
Guido Grandi ◽  
...  
Keyword(s):  
Phenotypic Diversity ◽  
Group B Streptococcus ◽  
Invasive Disease ◽  
Sequence Type ◽  
Nucleotide Polymorphisms ◽  
Adult Humans ◽  
Group B

scholarly journals Emergence of the First Levofloxacin-Resistant Strains of Streptococcus agalactiae Isolated in Italy

2015 ◽  
Vol 59 (4) ◽  
pp. 2466-2469 ◽  
Author(s):  
G. Piccinelli ◽  
F. Gargiulo ◽  
S. Corbellini ◽  
G. Ravizzola ◽  
C. Bonfanti ◽  
...  
Keyword(s):  
Clonal Complex ◽  
Group B Streptococcus ◽  
Sequence Type ◽  
Fluoroquinolone Resistance ◽  
Topoisomerase Iv ◽  
Double Mutation ◽  
Unknown Significance ◽  
Resistant Strains ◽  
Group B ◽  
High Level

ABSTRACTOf 901 group B streptococcus strains analyzed, 13 (1.4%) were resistant to levofloxacin (MICs of >32 μg/ml for seven isolates, 2 μg/ml for four isolates, and 1.5 μg/ml for four isolates). Mutations in the quinolone resistance-determining regions (QRDRs) of gyrase and topoisomerase IV were identified. A double mutation involving the Ser-81 change to Leu forgyrAand the Ser-79 change to Phe or to Tyr forparCwas linked to a high level of fluoroquinolone resistance. In addition, two other mutational positions inparCwere observed, resulting in an Asp-83-to-Tyr substitution and an Asp-83-to-Asn substitution. Different mutations were also observed ingyrB, with unknown significance. Most levofloxacin-resistant GBS strains were of serotype Ib and belonged to sequence type 19 (ST19) and clonal complex 19 (CC-19). Most of them exhibited theepsilongene.

scholarly journals Molecular Characteristics of IS 1216 Carrying Multidrug Resistance Gene Cluster in Serotype III/Sequence Type 19 Group B Streptococcus

mSphere ◽  
2021 ◽  
Author(s):  
Yong Zhi ◽  
Hyun Jung Ji ◽  
Jong Hyun Jung ◽  
Eui Baek Byun ◽  
Woo Sik Kim ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Bacterial Colonization ◽  
Group B Streptococcus ◽  
Sequence Type ◽  
Molecular Characteristics ◽  
Protein Vaccine ◽  
Multidrug Resistance Gene ◽  
Content Type ◽  
Vaccine Candidates ◽  
Group B

Most previously isolated group B streptococcus (GBS) strains express either the Srr1 or Srr2 glycoprotein, which plays an important role in bacterial colonization and invasion. These glycoproteins are potential protein vaccine candidates.

scholarly journals Variation in Macrophage Phagocytosis of Streptococcus agalactiae Does Not Reflect Bacterial Capsular Serotype, Multilocus Sequence Type or Association with Invasive Infection

2018 ◽  
Vol 3 (1) ◽  
pp. 63 ◽  
Author(s):  
Lisa M. Rogers ◽  
Jennifer A. Gaddy ◽  
Shannon D. Manning ◽  
David M. Aronoff
Keyword(s):  
Innate Immunity ◽  
Group B Streptococcus ◽  
Human Cell Line ◽  
Sequence Type ◽  
Clinical Isolates ◽  
Invasive Infection ◽  
Gram Positive ◽  
Macrophage Phagocytosis ◽  
Group B ◽  
Clinical Source

Background: Group B Streptococcus(GBS) is an encapsulated Gram-positive coccus that is an important cause of infections in adults with chronic medical conditions, pregnant women, and neonates. GBS causes a range of clinical syndromes, from asymptomatic colonization to deep-seated invasive and highly lethal infections. Macrophages are important sentinels of innate immunity, protecting host tissues from infection when bacteria advance beyond cutaneous or mucosal barriers. We hypothesized that the capacity for macrophages to phagocytose unopsonized GBS would vary across distinct clinical strains, and such differences would reflect serotype diversity.Methods: A high-throughput screen using the phorbol ester-differentiated THP-1 macrophage-like human cell line was used to quantify phagocytosis of a diverse group of 35 different human clinical isolates of GBS representing a wide variety of capsular serotypes. Validation studies were conducted using human primary phagocytes.Results: Phagocytosis of GBS differed widely across clinical isolates but this was not related to capsular serotype, genetic sequence type, pilus type, or clinical source of the GBS isolate (colonizing or invasive strain).Conclusions: Structural and/or biochemical differences among diverse GBS strains are reflected in a diverse capacity for macrophages to ingest them through non-opsonic phagocytosis. Mechanisms explaining these differences are not clear.Keywords: Neonatal sepsis; innate immunity; macrophages; Gram-positive bacteria; diabetes

Associations between capsular serotype, multilocus sequence type, and macrolide resistance inStreptococcus agalactiaeisolates from Japanese infants with invasive infections

2013 ◽  
Vol 142 (4) ◽  
pp. 812-819 ◽  
Author(s):  
M. MOROZUMI ◽  
T. WAJIMA ◽  
Y. KUWATA ◽  
N. CHIBA ◽  
K. SUNAOSHI ◽  
...  
Keyword(s):  
Clonal Complex ◽  
Vaccine Development ◽  
Late Onset ◽  
Group B Streptococcus ◽  
Sequence Type ◽  
Macrolide Resistance ◽  
Invasive Infections ◽  
Resistant Strains ◽  
Group B ◽  
Sequence Types

SUMMARYStreptococcus agalactiae(group B streptococcus; GBS) isolates (n = 150) from infants with invasive infections between 2006 and 2011 were analysed for capsular serotype, multilocus sequence type, and antibiotic susceptibility. In cases with late-onset disease (n = 115), primary meningitis was predominant (62·6%), but represented only 39·1% in cases with early-onset disease (n = 23). The most common serotype was III (58·7%), followed by Ia (21·3%) and Ib (12·7%). Sequence types (STs) of serotype III strains included ST17 (50·0%), ST19 (26·1%), ST335 (18·2%), ST27 (4·5%), and ST1 (1·1%). Predominant STs of serotypes Ia and Ib were ST23 (81·3%) and ST10 (84·2%), respectively. No penicillin-resistant strains were detected, but 22·0% of strains hadmef(A/E),erm(A), orerm(B) genes, which mediate macrolide resistance. A new ST335, possessing anmef(A/E) gene belonging to clonal complex 19 gradually increased in frequency. Improved prevention of invasive GBS infections in infants requires timely identification, and ultimately vaccine development.

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