scholarly journals Depressive symptoms in patients with epilepsy and clinically associated features in a single tertiary center

Author(s):  
Mariacarolina Vacca ◽  
Mariana Fernandes ◽  
Matteo Spanetta ◽  
Fabio Placidi ◽  
Francesca Izzi ◽  
...  

AbstractAlthough depressive symptoms are the most common psychiatric comorbidity in epilepsy, they remain underestimated and untreated in a large proportion of patients. The purpose of this study was to evaluate depression severity and related clinical features in people with epilepsy using a well-reliable self-report index of mood, the Beck Depression Inventory-II (BDI-II). One-hundred seventeen adult patients with epilepsy were recruited from a tertiary epilepsy center and completed the BDI-II. A single-item analysis of the 21 questions of the BDI-II was computed and differences between women and men in each depressive symptom were evaluated. Correlation and regression analyses were used to identify clinical features associated with the severity of depression. Results showed gender differences in some items, with women reporting overall higher depression severity than men. The most common symptoms regarded domains of sleeping patterns, tiredness, and loss of energy. Regression evidence suggested that being female, having an epilepsy duration < 10 years, as well as being treated with psychotropic drugs and reporting generalized seizure, were associated with higher depression severity. Despite its cross-sectional nature, this study reinforces the importance of investigating and possibly treating depressive symptoms in adult patients with epilepsy, since they negatively impact well-being, daytime activities, and sleep. Further studies identifying pharmacological and non-pharmacological treatments for depression in epilepsy need to be planned.

2021 ◽  
Author(s):  
Hany ElGindi ◽  
Reham Shalaby ◽  
April Gusnowski ◽  
Wesley Vuong ◽  
Shireen Surood ◽  
...  

BACKGROUND During the COVID-19 pandemic, threats to mental health, psychological safety, and well-being are evident, particularly among the first responders and the healthcare staff. OBJECTIVE This study aimed to examine the prevalence and the potential predictors of the likely stress, generalized anxiety disorder, and major depressive disorder among healthcare workers (HCW). METHODS A cross-sectional survey was used through a survey link sent to gather demographic information and responses on several self-report scales, including the Perceived Stress Scale (PSS), Generalized Anxiety Disorder 7-item (GAD-7) scale, and Patient Health Questionnaire-9 (PHQ-9) among the various HCW groupings who subscribed to the Text4Hope program. RESULTS This study revealed that the HCW expressed an estimated high prevalence of moderate/high stress rates 840 (81.2%), while the likelihood of moderate/severe anxiety and depressive symptoms were 369 (38.6%), and 317 (32.7%), respectively, during COVID-19 pandemic. Nurses and other HCW were significantly more likely to report depressive symptoms, compared to physicians, (F (2, 159.47) =15.89, 95% CI= (-5.05) -(-2.04). Younger age groups of HCW (≤30 y) were more prone to report likely stress, anxiety, and depressive symptoms, compared to HCW 41-50y and >50y (Odd’s ratio range: 1.82- 3.03). Similarly, females and those who reported a lack of social support (separated/divorced and single) among HCW, had a higher likelihood to report likely stress and depressive symptoms, respectively (OR=1.8 and 1.6). CONCLUSIONS This cross-sectional study revealed the significant impact of COVID-19 pandemic on mental health and indicated significant vulnerability among groups of HCW in Alberta. CLINICALTRIAL Ethical approval for this research was obtained through the University of Alberta Health Research Ethics Board (Pro00086163).


Author(s):  
Nikos L. D. Chatzisarantis ◽  
Sviatlana Kamarova ◽  
Chris Twomey ◽  
Graham Hansen ◽  
Mark Harris ◽  
...  

Abstract. Background: Previous research has documented that unemployed individuals who engage in recreational activities, either alone or with others, experience higher levels of mental health and psychological well-being relative to those who do not engage in recreational activities. Aims: In this study, we examined whether engagement in health promoting activities, alone or with other family members, is associated with reduced levels of depression and enhanced levels of life satisfaction in unemployed individuals. Method: We employed a cross-sectional design in which we measured life satisfaction, depressive symptoms, consumption of healthy meals and engagement in physical activities in 203 unemployed individuals (male = 90, female = 113, age= 33.79, SD = 11.16). Results: Independent of age, gender, and partner employment status, hierarchical regression analyses revealed statistically significant effects for social forms of healthy eating (consumption of healthy meals with others) and solitary forms of physical activity (exercising alone) on depressive symptoms and life satisfaction. Limitations: The research design was cross-sectional using self-report questionnaires. The present study does not to explain why and how health promoting activities enhance well-being outcomes among the unemployed. Conclusions: These findings highlight the importance of measuring engagement in health promoting activities through separate constructs that capture engagement in social and solitary health promoting activities and suggest that unemployed individuals are likely to experience optimal levels of psychological well-being if they exercise alone and consume healthy meals with other family members.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 896-897
Author(s):  
Emily Behrens ◽  
Kyrsten Hill ◽  
Dylan Smith ◽  
Jason DeCaro ◽  
Brian Cox ◽  
...  

Abstract Previous research has found a reciprocal relationship between pain and depression, in which each influences the severity of the other (Chou, 2007; Hawker et al., 2011, Kroenke et al., 2011; Schieir et al., 2009). Studies have found that depressed individuals exhibit stronger pain-mood associations than never-depressed individuals (Conner et al., 2006; Tennen et al., 2006). The current study investigated main and interactive effects of depressive symptoms on the momentary associations between pain and mood. Experience sampling (ESM) data was used from a multi-site study examining individuals with knee osteoarthritis (OA). Participants completed self-report measures of global depression and momentary pain, negative affect (NA), and positive affect (PA). Cross-sectional associations among momentary pain and affect were examined in a series of hierarchical multilevel models that nested the 28 ESM calls (Level 1) within participants (Level 2). A parallel set of multilevel models tested lagged associations among momentary variables. Depression significantly moderated the contemporaneous (p &lt; .001) and lagged (p &lt; .003) associations between pain and NA, suggesting that depression intensifies the momentary pain-NA linkage. There were no significant interaction effects for PA. These findings extend existing knowledge by illustrating how depressive symptoms influence the everyday experience of OA pain and its impact on affective well-being. (Supported by AG041655, P. Parmelee and D. Smith, Co-PIs)


Crisis ◽  
2011 ◽  
Vol 32 (5) ◽  
pp. 272-279 ◽  
Author(s):  
Allison S. Christian ◽  
Kristen M. McCabe

Background: Deliberate self-harm (DSH) occurs with high frequency among clinical and nonclinical youth populations. Although depression has been consistently linked with the behavior, not all depressed individuals engage in DSH. Aims: The current study examined maladaptive coping strategies (i.e., self-blame, distancing, and self-isolation) as mediators between depression and DSH among undergraduate students. Methods: 202 students from undergraduate psychology courses at a private university in Southern California (77.7% women) completed anonymous self-report measures. Results: A hierarchical regression model found no differences in DSH history across demographic variables. Among coping variables, self-isolation alone was significantly related to DSH. A full meditational model was supported: Depressive symptoms were significantly related to DSH, but adding self-isolation to the model rendered the relationship nonsignificant. Limitations: The cross-sectional study design prevents determination of whether a casual relation exists between self-isolation and DSH, and obscures the direction of that relationship. Conclusions: Results suggest targeting self-isolation as a means of DSH prevention and intervention among nonclinical, youth populations.


2002 ◽  
Vol 8 (6) ◽  
pp. 527-531 ◽  
Author(s):  
C-H Chang ◽  
D Cella ◽  
O Fernández ◽  
G Luque ◽  
P de Castro ◽  
...  

Objective: The cross-sectional study evaluated the psychometric properties of the Functional Assessment of Multiple Sclerosis (FAMS) Spanish version and its use in measuring quality of life (QOL) of multiple sclerosis (MS) patients in Spain. Methods: The FAMS is a factorially derived self-report scale designed to assess six primary aspects of QOL of patients with MS: Mobility, Symptoms, Emotional Well-Being, General Contentment, Thinking and Fatigue, and Family/Social Well-Being. Its Spanish translated version was used to assess QOL of 625 MS patients recruited in an outpatient clinic setting from 58 hospitals in Spain. Internal consistency of the Spanish FAMS was evaluated. Multiple regression analyses were performed to identify significant predictors from demographic, clinical and treatment characteristics, and Kurtzke Expanded Disability Status Scale (EDSS) scores in predicting FAMS scale scores. Results: Most of the patients are females (66%), and 74% were of the relapsing-remitting (RR) clinical subtype. Cronbach’s alpha coefficients were high (range=0.78-0.96), indicating subscale homogeneity comparable to that of the original English version. Linear multivariate regression analyses revealed that the EDSS is a dominant variable in predicting all the FAMS subscales, especially mobility (R2=0.51) and the total scores. Conclusions: The Spanish FAMS is a psychometrically valid instrument that allows clinicians and clinical researchers the ability to measure the QOL concerns of MS patients in Spain.


2012 ◽  
Vol 26 (5) ◽  
pp. 536-549 ◽  
Author(s):  
Bart Duriez ◽  
Theo A. Klimstra ◽  
Koen Luyckx ◽  
Wim Beyers ◽  
Bart Soenens

Because the authoritarian personality was introduced to explain the rise of fascism during World War II, research focused on its ability to predict prejudice, leaving its associations with well–being largely unexplored. Studies that did examine these associations yielded inconsistent results, and some authors even argued that authoritarianism buffers against the negative effects of psychological vulnerability factors (i.e. D–type personality) and negative life events on well–being, especially among people in an authoritarian environment. Using a cross–sectional community sample (N = 1010), Study 1 failed to support the idea that authoritarianism relates to depressive symptoms and buffers against the negative effects of D–type personality on depressive symptoms. Using a longitudinal college student sample (N = 499), Study 2 showed that authoritarianism did not moderate the effects of life events either and even predicted over–time increases in depressive symptoms. Using a longitudinal high school sample (N = 590), Study 3 showed that this effect emerged regardless of degree of fit with the social environment (i.e. with family and friends). Taken together, results suggest that authoritarianism constitutes a risk factor for rather than a protective factor against depressive symptoms. Copyright © 2011 John Wiley & Sons, Ltd.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e23557-e23557
Author(s):  
Jonathan R. Day ◽  
Benjamin Miller ◽  
Sarah L. Mott ◽  
Bradley T. Loeffler ◽  
Munir Tanas ◽  
...  

e23557 Background: Sarcomas are a diverse group of neoplasms that vary greatly in clinical presentation and responsiveness to treatment. Given the differences in the sites of involvement, rarity, and treatment modality, a multidisciplinary approach is required. Previous literature suggests patients with sarcoma suffer from poorer quality of life (QoL) especially physical and functional well-being. This study aims to understand if there is an association between treatment at a tertiary sarcoma center and a difference in QoL. Methods: De-identified data was obtained from the Sarcoma Tissue Repository at University of Iowa. Mixed effects regression models were utilized to evaluate the association between disease and treatment characteristics and QoL. QoL was assessed using the self-report FACT-G questionnaire at 12-, 24-, and 36-months post-diagnosis; overall scores and the 4 well-being subscales (Physical, Emotional, Social, Functional) were calculated. Results: 443 patients were identified. Soft tissue sarcomas were more prevalent (87.6%) than bone (12.4%). 53% of patients received chemotherapy and 38.6% got radiation therapy. Sarcomas were most frequently located in the lower extremities(ext.) (33.1%), followed by abdomen (20.9%), pelvic (13.6%), upper ext. (13.1%), thorax (11.3%), head & neck (7.8%). For ext. sarcoma; lower ext: 144 (71.3%), Upper ext: 58 (28.7%). Patients with extremity sarcoma; 133 had limb sparing and 48 had amputations. FACT-G Scores did not appreciably vary between 12, 24-, and 36-month for any QoL responses. Overall well-being had a mean score reported of 87.7 (sd = 15.7). Social well-being sores averaged 23.5 (5.0). Emotional well-being (EWB) 19.2 (4.1) and functional well-being (FWB) 21.3 (6.1), and physical well-being (PWB) 23.7 (4.6). There was no association between overall, PWB, EWB, or FWB with the histological subtype, radiation treatment, type of limb surgery, or any location in the same patients over time. Chemotherapy treatments were associated with lower well-being in multiple domains; PWB scores being 2.01 points lower, (p < 0.01), EWB scores being 1.27 points lower (p = 0.01) and FWB scores being 1.72 (p = 0.03), and 4.44 points lower overall (p = 0.03), on average, after adjusting for overall changes across time. Patients with ext. sarcoma only overall FACT-G scores differed 6.72 points higher for upper ext. than lower ext (p = 0.04). Conclusions: Overall QoL areas were similar to normative FACT-G scores both overall and specific areas. Having received chemotherapy was associated with lower well-being scores physically, emotionally, functionally, and overall. There were no clinically relevant differences reported in QoL scores between 12-,24-, and 36-months in the same patients. Further work is needed to describe QoL differences among patients with sarcoma at tertiary centers and examine what protective factors may influence patient well-being.


Author(s):  
Shinya Ito ◽  
Mie Sasaki ◽  
Satoko Okabe ◽  
Nobuhiro Konno ◽  
Aya Goto

Young women in their late teens and early 20s are at the highest risk for depression onset. The present study aimed to assess depressive symptoms among female college students in Fukushima. More specifically, it aimed to clarify factors predicting possible symptom profiles, with an emphasis on determining how nuclear radiation risks affect the reporting of depression symptoms. A cross-sectional survey was conducted of 310 female students at a college in the Fukushima prefecture, Japan, in December 2015, and 288 participants submitted valid questionnaires. In total, 222 (77.1%) participants lived in Fukushima at the time of the Great East Japan Earthquake. The measures included the World Health Organization-Five Well-Being Index, the Fukushima Future Parents Attitude Measure, and risk perception of radiation health effects. A total of 46.5% of participants reported depressive symptoms. Path analysis revealed that higher radiation risk perceptions and reduced efficacy with reproduction related to a decline in self-esteem and self-efficacy, which was subsequently associated with increased depressive symptoms. These findings highlight the importance of radiation education among children and young adults, both after a nuclear accident and during disaster preparation, particularly in the context of reproductive and mental health.


2017 ◽  
Vol 14 (4) ◽  
pp. 270-274 ◽  
Author(s):  
Kaori Ishii ◽  
Ai Shibata ◽  
Minoru Adachi ◽  
Yoshiyuki Mano ◽  
Koichiro Oka

Background:Sedentary behaviors (SB) are associated with health indicators; however, there are currently very few studies that have examined these associations, especially in conjunction with psychological factors, in children. The current study examined the independent relationship between objectively assessed SB, and indicators of obesity and psychological well-being, among Japanese children.Methods:A total of 967 elementary-school children completed a cross-sectional survey. SB was measured with accelerometers for 7 consecutive days. Psychological well-being data (eg, anxiety and behavior problems) were collected via a self-report questionnaire. To determine the relationship of SB with degree of obesity and psychological well-being, linear regression analyses were conducted to relate the indicators of obesity and psychological well-being on SB, adjusted by gender, grade, percentage of moderate-to-vigorous physical activity per day, duration spent wearing the accelerometer, and degree of obesity.Results:SB was significantly related to behavioral/emotional problems (β = .280, P = .010, R2 = .015). There was a statistically significant relationship between SB and anxiety (β = .206, P = .059, R2 = .007). No significant association with degree of obesity was found.Conclusions:Excess SB relates higher levels of behavioral/emotional problems and anxiety. These results can inspire the development of interventions that promote well-being and enhance psychological health, by focusing on SB in Japanese children.


2014 ◽  
Vol 48 (3) ◽  
pp. 469-476 ◽  
Author(s):  
Rosely Almeida Souza ◽  
Gislaine Desani da Costa ◽  
Cintia Hitomi Yamashita ◽  
Fernanda Amendola ◽  
Jaqueline Correa Gaspar ◽  
...  

Objective: To classify families of elderly with depressive symptoms regarding their functioning and to ascertain the presence of an association between these symptoms, family functioning and the characteristics of the elderly. Method: This was an observational, analytical, cross-sectional study performed with 33 teams of the Family Health Strategy in Dourados, MS. The sample consisted of 374 elderly divided into two groups (with and without depressive symptoms). The instruments for data collection were a sociodemographic instrument, the GeriatricDepression Scale (15 items) and the Family Apgar. Results: An association was observed between depressive symptoms and family dysfunction, female gender, four or more people living together, and physical inactivity. Conclusion: The functional family may represent effective support for the elderly with depressive symptoms, because it offers a comfortable environment that ensures the well-being of its members. The dysfunctional family can barely provide necessary care for the elderly, which can exacerbate depressive symptoms.



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