Engineering DNA logic systems with non-canonical DNA-nanostructures: basic principles, recent developments and bio-applications

2021 ◽  
Author(s):  
Daoqing Fan ◽  
Jun Wang ◽  
Jiawen Han ◽  
Erkang Wang ◽  
Shaojun Dong
Keyword(s):  
Dna Nanostructures ◽  
Basic Principles ◽  
Recent Developments ◽  
Logic Systems

scholarly journals Constructing Large 2D Lattices Out of DNA-Tiles

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1502
Author(s):  
Johannes M. Parikka ◽  
Karolina Sokołowska ◽  
Nemanja Markešević ◽  
J. Jussi Toppari
Keyword(s):  
Self Assembly ◽  
Dna Nanotechnology ◽  
Building Blocks ◽  
High Yield ◽  
Dna Nanostructures ◽  
Liquid Interfaces ◽  
Basic Principles ◽  
Dna Tiles ◽  
One Step ◽  
Solid Liquid

The predictable nature of deoxyribonucleic acid (DNA) interactions enables assembly of DNA into almost any arbitrary shape with programmable features of nanometer precision. The recent progress of DNA nanotechnology has allowed production of an even wider gamut of possible shapes with high-yield and error-free assembly processes. Most of these structures are, however, limited in size to a nanometer scale. To overcome this limitation, a plethora of studies has been carried out to form larger structures using DNA assemblies as building blocks or tiles. Therefore, DNA tiles have become one of the most widely used building blocks for engineering large, intricate structures with nanometer precision. To create even larger assemblies with highly organized patterns, scientists have developed a variety of structural design principles and assembly methods. This review first summarizes currently available DNA tile toolboxes and the basic principles of lattice formation and hierarchical self-assembly using DNA tiles. Special emphasis is given to the forces involved in the assembly process in liquid-liquid and at solid-liquid interfaces, and how to master them to reach the optimum balance between the involved interactions for successful self-assembly. In addition, we focus on the recent approaches that have shown great potential for the controlled immobilization and positioning of DNA nanostructures on different surfaces. The ability to position DNA objects in a controllable manner on technologically relevant surfaces is one step forward towards the integration of DNA-based materials into nanoelectronic and sensor devices.

scholarly journals Cell-Free Synthetic Biology Platform for Engineering Synthetic Biological Circuits and Systems

2019 ◽  
Vol 2 (2) ◽  
pp. 39 ◽  
Author(s):  
Dohyun Jeong ◽  
Melissa Klocke ◽  
Siddharth Agarwal ◽  
Jeongwon Kim ◽  
Seungdo Choi ◽  
...  
Keyword(s):  
Synthetic Biology ◽  
Free Expression ◽  
Dna Nanostructures ◽  
Expression Systems ◽  
Natural Systems ◽  
The Past ◽  
Current Cell ◽  
Recent Developments ◽  
Biological Circuits

Synthetic biology integrates diverse engineering disciplines to create novel biological systems for biomedical and technological applications. The substantial growth of the synthetic biology field in the past decade is poised to transform biotechnology and medicine. To streamline design processes and facilitate debugging of complex synthetic circuits, cell-free synthetic biology approaches has reached broad research communities both in academia and industry. By recapitulating gene expression systems in vitro, cell-free expression systems offer flexibility to explore beyond the confines of living cells and allow networking of synthetic and natural systems. Here, we review the capabilities of the current cell-free platforms, focusing on nucleic acid-based molecular programs and circuit construction. We survey the recent developments including cell-free transcription–translation platforms, DNA nanostructures and circuits, and novel classes of riboregulators. The links to mathematical models and the prospects of cell-free synthetic biology platforms will also be discussed.

scholarly journals The Reconstruction Of Cluster Mass Profiles From Image Distortions

1996 ◽  
Vol 173 ◽  
pp. 137-142
Author(s):  
Peter Schneider
Keyword(s):  
Basic Principles ◽  
Cluster Mass ◽  
Recent Developments ◽  
Mass Profiles

I will review the basic principles and some of the most recent developments of parameter-free reconstructions of cluster mass profiles from the distortions of background galaxy images.

An Overview and Recent Developments of Distinct Lattice Spring Model on Dynamic Fracturing of Rock

2014 ◽  
Vol 553 ◽  
pp. 507-512
Author(s):  
Gao Feng Zhao ◽  
Nasser Khalili
Keyword(s):  
Element Model ◽  
Discrete Element Model ◽  
Spring Model ◽  
Basic Principles ◽  
Lattice Spring Model ◽  
Recent Developments ◽  
Distinct Lattice Spring Model ◽  
Dynamic Fracturing ◽  
Dynamics Problems ◽  
Macroscopic Parameters

This paper presents some recent developments of the Distinct Lattice Spring Model (DLSM) on dynamic fracturing of rock. The DLSM is a micromechanics based discrete numerical model for rock dynamics problems. It provides an alternative tool for rock mechanics study. Compared with the classical Discrete Element Model (DEM), the DLSM can directly use macroscopic parameters without any requirement for calibration process. Another significant advantage is that the DLSM uses only half of the degree of freedoms, and therefore, is more computational efficient. Because of these advantages, it has been used in a number of fields, e.g., dynamic fracturing, wave propagation, and nuclear waste disposition. In this work, the basic principles of the DLSM and its latest developments will be outlined.

Traitement de l'air par biofiltration

1999 ◽  
Vol 26 (4) ◽  
pp. 402-424 ◽  
Author(s):  
Hasnaa Jorio ◽  
Michèle Heitz
Keyword(s):  
Current Knowledge ◽  
Industrial Applications ◽  
Biological Processes ◽  
Environmental Aspects ◽  
Basic Principles ◽  
Operational Conditions ◽  
Volatile Organic ◽  
Recent Developments ◽  
Treatment Technologies ◽  
Expensive Process

During several decades, there have been numerous studies and attempts in the field of the treatment of volatile organic solvent contaminated air, with the aim of finding a more efficient and less expensive process. In parallel with the traditional air treatment technologies, biological processes have emerged in recent years. Biofiltration appears to be a particularly preferred path due to its efficiency, its environmental aspects, and its lower costs. In this paper, the biofiltration technology is positioned in relation to conventional techniques and other biological air treatments. Subsequently, after a short historical account of biofiltration, the focus is put on the main objective of this literature review, presenting the current knowledge about the basic principles of the process, its applicability, operational conditions that influence performance and reliability of this process, and recent developments in mathematical biofilter modeling. Finally, industrial applications and biofiltration processing costs are briefly discussed.Key words: biofilter, VOC, biodegradation, modeling, kinetics, humidity, temperature, pH, nutrients, oxygen.[Journal translation]

The Recent Developments of Molecular Dynamics Simulation

2013 ◽  
Vol 444-445 ◽  
pp. 1370-1373
Author(s):  
Wen Hai Gai ◽  
Ran Guo ◽  
Yuan Yuan Liu
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulation ◽  
Rapid Development ◽  
Equations Of Motion ◽  
Dynamics Simulation ◽  
Impact Factors ◽  
Lagrange Equations ◽  
Time Step ◽  
Basic Principles ◽  
Recent Developments

Based on the development of nanomaterials and the research on performance parameters of materials, molecular dynamics simulation has been rapid development and application. It is widely found that the material's physical, mechanical and other properties are both closely related to its macroscopic state and microstructure [. In order to explore and understand the nature of the material properties we need to analyze various impact factors including macroscopic, mesoscopic and microscopic. This paper describes the basic concepts and methods of molecular dynamics. The contents are comprised of time step, formulas such as Lagrange equations of motion and Hamiltonian equations of motion. The basic principles and recent developments of molecular dynamics were reviewed.

Le béton projeté : nouveaux développements et applications

2000 ◽  
Vol 27 (2) ◽  
pp. 383-388 ◽  
Author(s):  
Marc Jolin ◽  
Pierre Lacombe
Keyword(s):  
Civil Engineering ◽  
Setting Time ◽  
Concrete Structures ◽  
Concrete Repair ◽  
Basic Principles ◽  
Dry Process ◽  
Air Content ◽  
The Third ◽  
General Rules ◽  
Recent Developments

This paper presents the most recent developments in shotcrete technology obtained in the last 5 years through the "Industrial Chair on Shotcrete and Concrete Repair" hosted at Laval University. The main goal of this paper is to inform those involved in the construction and repair of civil engineering concrete structures of the various possibilities of "shotcrete." The two first sections present the basic principles in pneumatic application of concrete along with the two processes in shotcrete technology, the dry-mix and wet-mix. The advantages of both processes as well as the general rules to follow in a shotcrete application are also presented and explained. The third and last section, the most important, highlights the latest developments in shotcrete technology. These developments concern the use of set accelerating admixtures in dry process shotcrete and their effects on the durability of materials, the use of liquid and powdered air-entraining admixtures in dry-mix shotcrete as well as the concept of "high initial air content" in wet mix shotcrete.Key words: shotcrete, set accelerator, air-entraining admixture, durability, setting time.

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