scholarly journals Effects of temperature and cellular interactions on the mechanics and morphology of human cancer cells investigated by atomic force microscopy

2015 ◽  
Vol 58 (9) ◽  
pp. 889-901 ◽  
Author(s):  
Mi Li ◽  
LianQing Liu ◽  
Ning Xi ◽  
YueChao Wang ◽  
XiuBin Xiao ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Cancer Cells ◽  
Human Cancer ◽  
Cellular Interactions ◽  
Force Microscopy ◽  
Human Cancer Cells ◽  
Atomic Force ◽  
Effects Of Temperature

Study of NSCLC cell migration promoted by NSCLC-Derived Extracellular Vesicle using atomic force microscopy

2021 ◽  
Author(s):  
Shuwei Wang ◽  
Jiajia Wang ◽  
Tuoyu Ju ◽  
Kaige Qu ◽  
Fan Yang ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Cell Migration ◽  
Cancer Cells ◽  
Extracellular Vesicles ◽  
Extracellular Vesicle ◽  
Cancer Microenvironment ◽  
Biological Processes ◽  
Force Microscopy ◽  
Atomic Force ◽  
Cellular Components

Extracellular Vesicles (EVs) secreted by cancer cells have a key role in the cancer microenvironment and progression. Previous studies have mainly focused on molecular functions, cellular components and biological processes...

Viscoelastic properties of doxorubicin-treated HT-29 cancer cells by atomic force microscopy: the fractional Zener model as an optimal viscoelastic model for cells

2019 ◽  
Vol 19 (3) ◽  
pp. 801-813 ◽  
Author(s):  
Maricela Rodríguez-Nieto ◽  
Priscila Mendoza-Flores ◽  
David García-Ortiz ◽  
Luis M. Montes-de-Oca ◽  
Marco Mendoza-Villa ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Cancer Cells ◽  
Viscoelastic Properties ◽  
Viscoelastic Model ◽  
Zener Model ◽  
Force Microscopy ◽  
Atomic Force ◽  
Fractional Zener Model ◽  
Ht 29

Quantitative Measurements of Intercellular Adhesion Strengths between Cancer Cells with Different Malignancies Using Atomic Force Microscopy

2019 ◽  
Vol 91 (16) ◽  
pp. 10557-10563 ◽  
Author(s):  
Hyonchol Kim ◽  
Kenta Ishibashi ◽  
Kosuke Matsuo ◽  
Atsushi Kira ◽  
Tomoko Okada ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Cancer Cells ◽  
Intercellular Adhesion ◽  
Force Microscopy ◽  
Quantitative Measurements ◽  
Atomic Force

scholarly journals Evaluation of 5-fluorouracil-treated lung cancer cells by atomic force microscopy

2019 ◽  
Vol 11 (39) ◽  
pp. 4977-4982 ◽  
Author(s):  
Xiaolin Jiang ◽  
Ke Ma ◽  
Cuihua Hu ◽  
Mingyan Gao ◽  
Jiashuo Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Atomic Force Microscopy ◽  
Cancer Cells ◽  
Side Effect ◽  
Drug Efficacy ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Small Cell Lung ◽  
Force Microscopy ◽  
Atomic Force

The drug efficacy and side-effect of 5-fluorouracil for non-small cell lung cancer cells were studied by atomic force microscopy.

scholarly journals Alteration of nanomechanical properties of pancreatic cancer cells through anticancer drug treatment revealed by atomic force microscopy

2021 ◽  
Vol 12 ◽  
pp. 1372-1379
Author(s):  
Xiaoteng Liang ◽  
Shuai Liu ◽  
Xiuchao Wang ◽  
Dan Xia ◽  
Qiang Li
Keyword(s):  
Mechanical Properties ◽  
Pancreatic Cancer ◽  
Atomic Force Microscopy ◽  
Cancer Cells ◽  
Young’S Modulus ◽  
Young's Modulus ◽  
Force Microscopy ◽  
Pancreatic Cancer Cells ◽  
Atomic Force ◽  
Aggressive Cancer

The mechanical properties of cells are key to the regulation of cell activity, and hence to the health level of organisms. Here, the morphology and mechanical properties of normal pancreatic cells (HDPE6-C7) and pancreatic cancer cells (AsPC-1, MIA PaCa-2, BxPC-3) were studied by atomic force microscopy. In addition, the mechanical properties of MIA PaCa-2 after treatment with different concentrations of doxorubicin hydrochloride (DOX) were also investigated. The results show the Young's modulus of normal cells is greater than that of three kinds of cancer cells. The Young's modulus of more aggressive cancer cell AsPC-1 is smaller than that of less aggressive cancer cell BxPC-3. In addition, the Young's modulus of MIA PaCa-2 rises with the increasing of DOX concentration. This study may provide a new strategy of detecting cancer, and evaluate the possible interaction of drugs on cells.

Sign in / Sign up

Export Citation Format

Share Document