Uric acid, calcium and phosphorus clearances in normal subjects on a low calcium, low phosphorus diet: Uric acid, calcium and phosphorus clearances after calcium infusion in normal and gouty patients

Metabolism ◽  
1965 ◽  
Vol 14 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Cristobal G. Duarte ◽  
John H. Bland
1978 ◽  
Vol 40 (1) ◽  
pp. 159-162 ◽  
Author(s):  
Barbara A. Sommerville ◽  
J. Fox ◽  
A. D. Care ◽  
R. Swaminathan

1. Homogenates of pig kidney incubated in vitro convert 25-hydroxycholecalciferol to the dihydroxy-metabolites almost as efficiently as homogenates of chick kidney under similar conditions.2. The cortex of the kidney carries out this conversion more efficiently than does the medulla.3. Kidneys from pigs given low calcium or low phosphorus diets produce about 40 % more 1,25-dihydroxy cholecalciferol than those from pigs given diets containing normal levels of Ca and P.


1961 ◽  
Vol 39 (3) ◽  
pp. 220-224
Author(s):  
Frances A. Johnston ◽  
Rebecca A. Folsom

2021 ◽  
Author(s):  
Shivani Katoch ◽  
Sumani Sharma ◽  
Varun Sankhyan ◽  
Daisy Wadhwa ◽  
Arun Sharma ◽  
...  

Abstract A study was conducted to evaluate citric acid (CA) as an additive in poultry broiler diet with lower mineral density of calcium and phosphorus in commercial broiler poultry birds under complete randomized design. For this purpose, Vancobb-400 strain day old broiler chicks (n=320) were divided into 4 main treatment groups T0, T1, T2 and T3. Each treatment group was further divided into8 replicates with 10 chicks in each. T0 served as control diet and was given standard corn- soy flake based ration(Pre-starter%; CP;Ca;TP--23,1.00,0.70, Starter;22,1.10,0.72 and Finisher;20,0.99.70)and treatment T1 served as standard ration with added 0.5 per cent CA with no change in chemical composition (Pre-starter %; CP;Ca;TP23,1.00,0.70, Starter; 22,1.10,0.72 and Finisher;20,0.99.70). Treatment T2 was given standard cornsoy flake based ration containing 0.5 per cent CA with low calcium (Ca) and total phosphorus (TP) content (Pre-starter %; CP;Ca;TP --23,0.90,0.66,Starter; 22,0.99,0.71 and Finisher;20,0.90,0.69)whereas treatment T3 was given standard corn- soy flake based ration containing 0.5 per cent CA with moderately low calcium (Ca) and total phosphorus (TP) content(Pre-starter %;CP;Ca;TP--23,0.80,0.65,Starter;22,0.88,0.70 and Finisher;20,0.79,0.68)as per ICAR (2013) standards. Perusal of the results revealed that broiler birds offered moderately low Ca and TP exhibited higher growth performance (P<0.05) for gain in weight, feed intake, feed conversion efficiency and carcass traits viz. dressing percentage and forequarters weight. Addition of 0.5 per cent CA in low and moderately low Ca and TP offered diets conferred protection to birds by lowering mortality in birds through reduction in total microbial count in the lower gastro intestinal tract. Results of the experiment revealed activation of homeostatic mechanisms in birds offered moderately low Ca and TP with added 0.5% CA modulating enhanced availability of calcium and phosphorus as evident in metabolic trial, blood and tibiae bone studies but the homeostatic mechanism was less pronounced when Ca and TP density in diet was low. Overall economics exhibited lowest cost of producing, per kg live weight in broiler birds offered moderately low Ca and TP with added 0.5 % CA. In conclusion, birds offered corn soya based diet with moderately low mineral viz. calcium and total phosphorus as per ICAR 2013 standard with added 0.5 per cent citric acid can enhance the growth, improve carcass characteristics and improve the FCR of broilers though favourable environment in lower intestinal tract and activation of homeostatic mechanisms of calcium and phosphorus digestion and absorption, thus economizing the cost of production.


2021 ◽  
Vol 15 ◽  
Author(s):  
Haochen Guan ◽  
Zhi Geng ◽  
Weijie Yuan ◽  
Bowen Chang

Uric acid (URIC) is a natural antioxidant, and it has been shown that low levels of URIC could be a risk factor for the development of Parkinson’s disease. Our aim was to investigate whether URIC also plays a role in Meige’s syndrome (MS). We conducted a cohort study to compare serum URIC levels between patients with MS and healthy controls. In addition, we analyzed the impact of URIC on the risk of MS and symptom severity. Compared with normal subjects, URIC content was remarkably decreased in MS patients. In addition, URIC was regarded as a protective factor for MS, as verified by multivariate logistic regression models. We also found non-linear relationships between the levels of serum URIC and the incidence rate of MS and the Burke-Fahn-Marsden dystonia rating scale score. Our study is the first to show a connection between serum URIC levels and MS. Low serum URIC levels indicate an increased risk of MS incidence and more severe clinical symptoms. Our findings provide new insights into the prevention and treatment of MS.


1957 ◽  
Vol 3 (3) ◽  
pp. 156-159 ◽  
Author(s):  
Eugene L Kanabrocki ◽  
Joseph Greco ◽  
Lee Wilkoff ◽  
Roger Veach

Abstract 1. A comparison has been made of plasma values obtained by 5 different methods for uric acid estimation. 2. According to the uricase method, the plasma concentration of uric acid in fasting normal subjects ranged from 1.9-5.1 with average of 3.7 mg. per 100 ml. 3. The closest agreement with the uricase method was obtained with the method of Kern and Stranaky which gave normal values ranging from 2.8 to 4.9 with an average of 3.8 mg. per 100 ml. 4. A variation of about 25 per cent was observed in the plasma uric acid levels over a period of 7 weeks.


1959 ◽  
Vol 67 (1) ◽  
pp. 59-68 ◽  
Author(s):  
I. Zipkin ◽  
R. C. Likins ◽  
F. J. McClure

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