Evaluating and adapting new technologies in a high-risk agricultural system—Niger

1993 ◽  
Vol 42 (1-2) ◽  
pp. 153-171 ◽  
Author(s):  
B.I. Shapiro ◽  
J.H. Sanders ◽  
K.C. Reddy ◽  
T.G. Baker
Keyword(s):  
High Risk ◽  
New Technologies ◽  
Agricultural System

scholarly journals New technologies for high-risk tunnel construction in Guiyang-Guangzhou high-speed railway

2013 ◽  
Vol 21 (4) ◽  
pp. 258-265 ◽  
Author(s):  
Yubao Zhao ◽  
Shougen Chen ◽  
Xinrong Tan ◽  
Ma Hui
Keyword(s):  
High Risk ◽  
High Speed ◽  
New Technologies ◽  
Tunnel Construction ◽  
High Speed Railway

Formulate a Clear M&A Strategy

2020 ◽  
pp. 17-31
Author(s):  
Timothy Galpin
Keyword(s):  
High Risk ◽  
Best Practices ◽  
Mergers And Acquisitions ◽  
Stock Prices ◽  
New Technologies ◽  
Strategic Choice ◽  
Growth Strategy ◽  
Ample Evidence ◽  
Cross Border ◽  
Strategic Options

Mergers and acquisitions are a strategic choice. Favorable regulatory environments, economic expansion, the emergence of new technologies, high stock prices, and liquidity in credit markets have all contributed to creating “waves” of M&A characterized by periods of high and low transaction volumes. M&A is a high-risk growth strategy, with ample evidence demonstrating that buyers struggle to capture value from their transactions. Yet, the Oxford M&A Insights Project found that almost two-thirds (64%) of respondents indicated that their company is “very likely” or “likely” to conduct future transactions. This chapter provides an overview of the strategic options for M&A and how firms develop their M&A strategies. The tools, templates, best practices, potential pitfalls, and a case example of how to go about setting a clear M&A strategy are also addressed, along with the main participants, core activities, buyer’s and seller’s perspectives, and key cross-border considerations.

Parents’, Health Care Professionals’, and Scientists’ Experiences of a Precision Medicine Pilot Trial for Patients With High-Risk Childhood Cancer: A Qualitative Study

2019 ◽  
pp. 1-11 ◽  
Author(s):  
Janine Vetsch ◽  
Claire E. Wakefield ◽  
Emily Duve ◽  
Brittany C. McGill ◽  
Meera Warby ◽  
...  
Keyword(s):  
Health Care ◽  
High Risk ◽  
Childhood Cancer ◽  
Precision Medicine ◽  
Health Care Professionals ◽  
New Technologies ◽  
Pilot Trial ◽  
Treatment Recommendations ◽  
Laboratory Research ◽  
Drug Access

PURPOSE Children with high-risk cancers have low survival rates because current treatment options are limited. Precision medicine trials are designed to offer patients individualized treatment recommendations, potentially improving their clinical outcomes. However, parents’ understanding is often limited, and expectations of benefit to their own child can be high. Health care professionals (HCPs) are often not familiar with precision medicine and might find managing families’ expectations challenging. Scientists find themselves working with high expectations among different stakeholders to rapidly translate their identification of actionable targets in real time. Therefore, we wanted to gain an in-depth understanding of the experiences of all stakeholders involved in a new precision medicine pilot trial called TARGET, including parents, their child’s HCPs, and the scientists who conducted the laboratory research and generated the data used to make treatment recommendations. METHODS We conducted semistructured interviews with all participants and analyzed the interviews thematically. RESULTS We interviewed 15 parents (9 mothers; 66.7% bereaved), 17 HCPs, and 16 scientists. We identified the following themes in parents’ interviews: minimal understanding and need for more information, hope as a driver of participation, challenges around biopsies, timing, and drug access, and few regrets. HCP and scientist interviews revealed themes such as embracing new technologies and collaborations and challenges managing families’ expectations, timing of testing and test results, and drug access. CONCLUSION Educating families, HCPs, and scientists to better understand the benefits and limitations of precision medicine trials may improve the transparency of the translation of discovery genomics to novel therapies, increase satisfaction with the child’s care, and ameliorate the additional long-term psychosocial burden for families already affected by high-risk childhood cancer.

scholarly journals Low/High-risk Earmolds: New Technologies and their Application from 2019 to the Present

2019 ◽  
pp. 1-3
Author(s):  
Barbero A ◽  
Keyword(s):  
High Risk ◽  
Hearing Aids ◽  
Soft Tissues ◽  
New Technologies ◽  
Hearing Aid ◽  
Excessive Pressure ◽  
Small Probe ◽  
The Family ◽  
Sound Feedback ◽  
Very High

Until 2019, hearing aid molds were made with silicones that copied the shape of the ear, creating a positive and a negative mold to reproduce the shape and volume in cubic centimeters of the ear. This system had the disadvantage of lack of precision. Due to the pressure of the silicones during their placement in the ear, the soft tissues are deformed. This is especially important when the deafness is severe or profound. Because a very high sound power is required and sound leakage occurs. That leaking sound is feedback into the hearing aid microphone and generates a “Larsen effect.” Patients describe this sound feedback as very high-pitched beeps from the hearing aid that can be heard by family and others close to them. During the time that the hearing aid is whistling, the user loses information and hearing, as well as being annoying for the family. In the case of high-powered hearing aids, it is difficult to balance the sound leakage that generates the “Larsen effect” and the excessive pressure that forms the canal. Also bear in mind that the user of this type of hearing aid uses it all day, so a little discomfort translates into anguish and nervousness. This is not an easy task for the audiologist, nor for the laboratory technician making ear molds. They are known by the technicians as “High Risk Feedback Molds”. Recently, 3D laser light measurement has been used for measurements. By not having contact with the skin, this new technique allows the tissues not to deform. And it gives us a view from inside the ear (and this is another novelty) because they are done by means of a small probe that acts as a laser beam that we introduce into the ear canal itself.

Successful Implementation of New Technologies in Sour Oman Fields: Securing High Risk Wells, Savings & Production Increase

2018 ◽  
Author(s):  
Tushar Narwal ◽  
Yaqoob Riyami ◽  
Mansoor Rashdi ◽  
Zahir Abri ◽  
Aisha Sariri ◽  
...  
Keyword(s):  
High Risk ◽  
New Technologies ◽  
Successful Implementation ◽  
Production Increase

An Impact of New Technologies on Cropping Pattern in the Eastern Hills of Nepal

2020 ◽  
Vol 10 ◽  
pp. 197-210
Author(s):  
Shyam Prasad Wagle
Keyword(s):  
New Technologies ◽  
Group Discussion ◽  
Secondary Data ◽  
Agricultural System ◽  
Cropping Pattern ◽  
Governmental Organizations ◽  
Innovative Methods ◽  
Wide Range ◽  
The Government ◽  
The Impact

This abstract starts with the purpose of the study of the impact of using new technologies on cropping pattern particularly in the case of the Eastern hills. It also examines the role of governmental organizations and non-governmental organizations to improve agricultural systems of this area. Relevant data have been obtained from both primary and secondary sources. It draws on the data collected from interview, focus group discussion, key informant survey, and field observation. For this, 30 percent sample households were selected from three altitude belts such as upper, middle and lower, ranging from 300 to 2,250 masl along the Koshi-highway. It has a wide range of climates, ranging from sub-tropical to alpine with monsoon precipitation in the summer for three and half months, and therefore it has diversity in flora and fauna and people. Similarly, secondary data have been collected from various books, journals and official records. This paper has showed that the crucial impact of acceptance of innovative methods in agriculture in the study area is a joint effort of local people, government, and non-government agencies too. The government with the development agencies and non-government organizations has contributed to impart knowledge of the agriculture innovative methods to the local farmers. At the same time, the farmers were enthusiastic to learn and adopt those methods. Consequently, one can easily see the remarkable changes in cropping pattern due to the impact of such innovations. The cereal crops based on agricultural system is gradually moving towards high value off-season crops farming.

OP160 Enhancing Innovation Through HTA: Experience From South Australia

2018 ◽  
Vol 34 (S1) ◽  
pp. 58-58
Author(s):  
Naomi Burgess ◽  
Deborah Chen
Keyword(s):  
Decision Making ◽  
High Risk ◽  
Clinical Outcomes ◽  
State Government ◽  
New Technologies ◽  
Specific Treatment ◽  
South Australia ◽  
Health Technologies ◽  
Hospital Networks ◽  
Decision Making Criteria

Introduction:A statewide health technology assessment (HTA) program was implemented to increase equity of access and support robust assessment of technologies, with a focus on those that are high-cost, high-risk, or have state-wide impact.Methods:Local hospital networks and clinicians refer technologies to the South Australia Policy Advisory Committee on Technology (SAPACT) for assessment. Independently produced, comprehensive HTA reports are developed using internationally recognized evidence and critical appraisal methodologies. Clinical and economic systematic analyses are utilized, with extensive clinical consultation, to develop recommendations for new technologies and their role in models of care. Feasibility of adoption and local implementation are considered, including existing service delivery and appropriate training and credentialing. For approved technologies, SAPACT may also develop audit criteria and seek implementation reports on clinical outcomes.Results:The HTA framework has been successfully adopted across South Australia Health, increasing the incorporation of evidence-based decision making in the use of high-cost and high-risk health technologies. Over 35 evidence evaluations for high-risk and high-cost health technologies have been conducted for a broad range of treatment interventions. SAPACT develops and utilizes HTA decision-making criteria for transparency of Committee considerations. The program recommends adoption or rejection of technologies, or it may request a re-submission due to safety concerns or a lack of proven effectiveness. SAPACT has also granted temporary approval through adoption under clinical evaluation to inform investment decisions. A key component is working with clinicians to define specific treatment criteria and patient selection. SAPACT continues to strengthen relationships with all stakeholders, increase patient input through the development of public summary documents for technologies, and improve monitoring and reporting of clinical outcomes.Conclusions:The HTA program has been very productive and positively received. The success of the program is underpinned by its engagement with clinicians, hospital networks, and consumers. The completion of SAPACT HTA reviews and the publication of the SAPACT decision-making criteria have increased the credibility of decisions, supporting enhancements in patient care and cost efficiency for the state government.

Online Trading's Impacts on Western Manufacturers' Entry Modes in China

2002 ◽  
Vol 05 (04) ◽  
pp. 491-507
Author(s):  
Lee Li
Keyword(s):  
High Risk ◽  
New Technologies ◽  
End Users ◽  
Low Risk ◽  
Entry Modes ◽  
Specific Knowledge ◽  
Online Trading ◽  
Inductive Study ◽  
High Control ◽  
Positive Impacts

How does online trading affect Western manufacturers' entry modes in China? This inductive study of 20 Western manufacturers and their Chinese intermediaries led to propositions exploring that question. Findings from the study indicate that online trading intensifies the information exchanges between Western manufacturers and their Chinese end users. Such information exchanges provide Western manufacturers with detailed market-specific knowledge. Moreover, online trading intensifies the competition between Western manufacturers as their customers can keep well-informed of their product qualities, new technologies, and prices. Online trading has great positive impacts on Western manufacturers' shift from low-control and low-risk entry modes to high-control and high-risk entry modes.

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