Psychogenic paranoid psychosis: an empirical study

1996 ◽  
Vol 11 (4) ◽  
pp. 180-184 ◽  
Author(s):  
N Vicente ◽  
E Ochoa ◽  
B Rios
Keyword(s):  
Empirical Study ◽  
Social Adaptation ◽  
Stress Factors ◽  
Response To Treatment ◽  
Trigger Factors ◽  
Favourable Response ◽  
Level Of Functioning ◽  
Previous Level ◽  
Paranoid Psychosis

SummaryThe present study was aimed at assessing the psychopathological manifestations, stress factors, evolution and social adaptation of 29 patients diagnosed with psychogenic paranoid psychosis. This syndrome is seen as an entity in itself, and is closely related to trigger factors; stability in the symptomatology of each relapse; favourable response to treatment; tendency to relapse, and recovery of the previous level of functioning.

The features of viability and social adaptation of patients who underwent revisional hip replacement

2020 ◽  
pp. 60-63
Author(s):  
Elena Senina
Keyword(s):  
Empirical Study ◽  
Hip Replacement ◽  
Individual Characteristic ◽  
Social Adaptation ◽  
Structural Element ◽  
Postoperative Rehabilitation ◽  
Physical Recovery ◽  
Research Institute

The author analyzes the category of viability as a structural element of social adaptation of patients who underwent revisional hip replacement. Considering the process of postoperative rehabilitation, the author focuses on viability as an individual characteristic of patients, which determines the effectiveness of physical recovery and social adaptation after hip replacement. The article observes the results of an empirical study conducted on the basis of Saratov Research Institute of Traumatology and Orthopedics of Minzdrav of Russia, aimed at studying the criteria of viability and social viability of adaptation and social adaptation.

scholarly journals Identification of a novel autoantigen eukaryotic initiation factor 3 associated with polymyositis

Rheumatology ◽  
2019 ◽  
Vol 59 (5) ◽  
pp. 1026-1030 ◽  
Author(s):  
Zoe Betteridge ◽  
Hector Chinoy ◽  
Jiri Vencovsky ◽  
John Winer ◽  
Kiran Putchakayala ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Indirect Immunofluorescence ◽  
Mass Spectrometry Analysis ◽  
Initiation Factor ◽  
Response To Treatment ◽  
Healthy Controls ◽  
Eukaryotic Initiation Factor ◽  
Favourable Response ◽  
Cell Extracts ◽  
Cytoplasmic Complex

Abstract Objectives To describe the prevalence and clinical associations of autoantibodies to a novel autoantigen, eukaryotic initiation factor 3 (eIF3), detected in idiopathic inflammatory myositis. Methods Sera or plasma from 678 PM patients were analysed for autoantigen specificity by radio-labelled protein immunoprecipitation (IPP). Samples immunoprecipitating the same novel autoantigens were further analysed by indirect immunofluorescence and IPP using pre-depleted cell extracts. The autoantigen was identified through a combination of IPP and MALDI-TOF mass spectrometry, and confirmed using commercial antibodies and IPP-western blots. Additional samples from patients with DM (668), DM-overlap (80), PM-overlap (191), systemic sclerosis (150), systemic lupus erythematosus (200), Sjogren’s syndrome (40), rheumatoid arthritis (50) and healthy controls (150) were serotyped by IPP as disease or healthy controls. Results IPP revealed a novel pattern in three PM patients (0.44%) that was not found in disease-specific or healthy control sera. Indirect immunofluorescence demonstrated a fine cytoplasmic speckled pattern for all positive patients. Mass spectrometry analysis of the protein complex identified the target autoantigen as eIF3, a cytoplasmic complex with a role in the initiation of translation. Findings were confirmed by IPP-Western blotting. The three anti-eIF3-positive patients had no history of malignancy or interstitial lung disease, and had a favourable response to treatment. Conclusion We report a novel autoantibody in 0.44% of PM patients directed against a cytoplasmic complex of proteins identified as eIF3. Although our findings need further confirmation, anti-eIF3 appears to correlate with a good prognosis and a favourable response to treatment.

Clozapine: the Holywell experience with the first 24 patients

1993 ◽  
Vol 10 (1) ◽  
pp. 30-34 ◽  
Author(s):  
David J King ◽  
Philip J Mills
Keyword(s):  
Antipsychotic Drugs ◽  
Chronic Schizophrenic ◽  
Level Of Functioning ◽  
Duration Of Illness ◽  
Previous Level

AbstractClozapine was substituted for standard antipsychotic drugs in the treatment of 24 chronic schizophrenic inpatients and the response assessed after a mean of ten months. The majority (71%) improved (33.3% markedly), on their previous level of functioning. The response was better in those under 40 years of age, but neither duration of illness nor previous neuroleptic dose appeared to predict response to clozapine. The drug was ultimately discontinued in five (21%) patients – in three because of non-response and intolerance of sedation and in two because of neutropenia.

scholarly journals Conversion Disorder in Children: Characteristics and Gender Differences

2016 ◽  
Vol 3 (2) ◽  
Author(s):  
M Anupama ◽  
Uttam Shelar ◽  
Jitty George ◽  
Babool Raja
Keyword(s):  
Gender Differences ◽  
Interpersonal Relationships ◽  
Conversion Disorder ◽  
Complete Recovery ◽  
Stress Factors ◽  
Response To Treatment ◽  
Motor Disorder ◽  
Conversion Disorders ◽  
Common Diagnosis ◽  
And Gender

Aim: To study the clinical presentations and gender differences of conversion disorder in children less than 16 year old and correlate it with socio-demographic characteristics and stress factors. Methods: All case records of children presenting to psychiatry unit of a general hospital during last 5 years (both outpatient and inpatient) and having a diagnosis of ICD-10 Dissociative (conversion) disorders, were reviewed. Results: A total of 12 % ( n=512) had a diagnosis of conversion disorder, both genders having equal representation. Dissociative motor disorder was more common among males and dissociative convulsions among females. Academic and strained interpersonal relationships were the most common stress factors. Majority had la belle indifference and secondary gain and received outpatient treatment, and had complete recovery at last follow up. Conclusions: Conversion disorders are one of the most common diagnosis. Significant gender differences in mode of presentation and nature of stress are present. However the response to treatment is prompt and chance of recovery is high in both genders. Relevance: This study was done in a developing country where conversion disorder is seen commonly.

scholarly journals Detection of contradictions by linguistically gifted younger students: features of frustration and creativity

2019 ◽  
Vol 70 ◽  
pp. 08006
Author(s):  
Alla Belousova ◽  
Yulia Mochalova ◽  
Ljupco Kevereski ◽  
Olga Block
Keyword(s):  
Elementary School ◽  
Empirical Study ◽  
Social Environment ◽  
Elementary School Students ◽  
School Children ◽  
Comprehensive School ◽  
Social Adaptation ◽  
English School ◽  
School Students

The article presents an analysis of the results of an empirical study aimed at studying the ability to detect contradictions by younger students and the role of frustration and creativity in this process. Two groups of school children took part in the study: from a specialized English school that were identified as linguistically gifted (27 people, Rostov-on-Don), and from a municipal comprehensive school (27 people, Novocherkassk). In the study the following methods were used: V.E. Klochko aimed at determining the ability to detect contradictions, a brief test of creativity of E.P. Torrens and a children’s version of the Rosenzweig technique. The study obtained results demonstrating among linguistically gifted elementary school students: higher results in the development of the ability to detect contradictions, as well as the presence of pronounced differences in the development of measures of individual adaptation to their social environment (OSK), the dominance of self-protective reactions (ED), impunitive (M) and extrapunitive (E). A correlated interrelation was found between the ability to detect contradictions, originality, directionality of frustration reactions (M), (I) and the degree of social adaptation (GCR).

Gender Differences in Schizophrenia

1982 ◽  
Vol 27 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Mary V. Seeman
Keyword(s):  
Gender Differences ◽  
Protective Factors ◽  
Left Hemisphere ◽  
Early Onset ◽  
Age Of Onset ◽  
Stress Factors ◽  
Response To Treatment ◽  
Cumulative Stress

Men with schizophrenia have an earlier age of onset, a somewhat inferior response to treatment and a generally poorer prognosis than women. These findings can perhaps be explained by the existence of two distinct forms of the illness, one with early onset, primarily affecting men, and one with later onset, primarily affecting women. There is not much evidence for this first view. Alternatively, non-specific cumulative stress factors may impinge selectively on the male, reaching the threshold of demonstrable illness at an earlier age. A third possibility is the existence of specific biological protective factors in the female, such as relatively bilateral representation of left hemisphere functions or relative dopaminergic inhibition by estrogens.

A Clinical Study of Clozapine Treatment and Predictors of Response in a Canadian Sample

1995 ◽  
Vol 40 (4) ◽  
pp. 208-211 ◽  
Author(s):  
G. Honer William ◽  
G. William Macewan ◽  
Lili Kopala ◽  
Siemion Altman ◽  
Sherri Chisholm-Hay ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Clinical Study ◽  
Clinical Response ◽  
Severity Of Illness ◽  
Open Trial ◽  
Controlled Clinical Trials ◽  
Favourable Response ◽  
Clozapine Treatment ◽  
Level Of Functioning ◽  
Predictors Of Response

Objective To study the clinical response to clozapine in patients with refractory schizophrenia. Method Open trial of clozapine in 61 consecutively-treated patients. Results Following clozapine, the level of function of patients was improved relative to admission (p = 0.0001) and to the highest level in the previous year (p = 0.0001). Severity of illness was decreased (p = 0.0001). Overall, 31% of the patients were classified as responders to clozapine and the responders were all identified by 32 weeks of treatment. Poor functioning in the previous year was associated with less favourable response. At a mean interval of 26 months following discharge, 72% of the patients were continuing clozapine treatment. Conclusions This open trial of patients who were treated consecutively indicates a comparable degree of response to clozapine as observed in controlled clinical trials, and that level of functioning in the previous year was the best predictor of response.

Effects of regular musical life on social adaptation skill of 4th graders: an empirical study

2013 ◽  
Vol 5 (2) ◽  
pp. 14-19
Author(s):  
Tuncay Dilci ◽  
Saik Sivaci ◽  
Ayla Arseven ◽  
A.Burak Yildirim
Keyword(s):  
Empirical Study ◽  
Social Adaptation ◽  
Musical Life
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