scholarly journals Recording In Situ Human Remains in Three Dimensions

Author(s):  
Priscilla F. Ulguim
2019 ◽  
Vol 336 ◽  
pp. 169-173 ◽  
Author(s):  
Amélie Rochet ◽  
Ana Flávia Suzana ◽  
Aline R. Passos ◽  
Tiago Kalile ◽  
Felisa Berenguer ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jérôme Carnis ◽  
Aseem Rajan Kshirsagar ◽  
Longfei Wu ◽  
Maxime Dupraz ◽  
Stéphane Labat ◽  
...  

AbstractAt the nanoscale, elastic strain and crystal defects largely influence the properties and functionalities of materials. The ability to predict the structural evolution of catalytic nanocrystals during the reaction is of primary importance for catalyst design. However, to date, imaging and characterising the structure of defects inside a nanocrystal in three-dimensions and in situ during reaction has remained a challenge. We report here an unusual twin boundary migration process in a single platinum nanoparticle during CO oxidation using Bragg coherent diffraction imaging as the characterisation tool. Density functional theory calculations show that twin migration can be correlated with the relative change in the interfacial energies of the free surfaces exposed to CO. The x-ray technique also reveals particle reshaping during the reaction. In situ and non-invasive structural characterisation of defects during reaction opens new avenues for understanding defect behaviour in confined crystals and paves the way for strain and defect engineering.


1980 ◽  
Vol 20 (06) ◽  
pp. 533-554 ◽  
Author(s):  
Keith H. Coats

Abstract This paper describes a numerical model forsimulating wet or dry, forward or reverse combustionin one, two, or three dimensions. The formulation isconsiderably more general than any reported to date.The model allows any number and identities ofcomponents. Any component may be distributed inany or all of the four phases (water, oil, gas, andsolid or coke.The formulation allows any number of chemicalreactions. Any reaction may have any number ofreactants, products, and stoichiometry, identifiedthrough input data. The energy balance accounts forheat loss and conduction, conversion, and radiationwithin the reservoir.The model uses no assumptions regarding degreeof oxygen consumption. The oxygen concentration iscalculated throughout the reservoir in accordancewith the calculated fluid flow pattern and reactionkinetics. The model, therefore, simulates the effectsof oxygen bypassing caused by kinetic-limitedcombustion or conformance factors.We believe the implicit model formulation resultsin maximum efficiency (lowest computing cost), andrequired computing times are reported in the paper.The paper includes comparisons of model resultswith reported laboratory adiabatic-tube test results.In addition, the paper includes example field-scalecases, with a sensitivity study showing effects on oilrecovery of uncertainties in rock/fluid properties. Introduction Recent papers by Ali, Crookston et al., andYoungren provide a comprehensive review of earlierwork in numerical modeling of the in-situcombustion process.The trend in this modeling has been toward morerigorous treatment of the fluid flow and interphasemass transfer; inclusion of more components, morecomprehensive reaction kinetics, and stoichiometry;and more implicit treatment of the finite differencemodel equations.The purpose of this work was to extend thegenerality of previous models while preserving orreducing the associated computing-time requirement.The most comprehensive or sophisticated combustionmodels described to date appear to be thoseof Crookston et al. and Youngren. Therefore, wecompare our model formulation and results here withthose models.A common objective of different investigators'efforts in modeling in-situ combustion is developmentof more efficient formulations and methods ofsolution. This is especially important in thecombustion case because of the large number ofcomponents and equations involved. For a given numberof components and reactions, computing time pergrid block per time step will increase rapidly as theformulation is rendered more implicit. However, increasing implicitness tends to allow larger timesteps, which in turn reduces overall computingexpense. To pursue the above objective, then, authorsshould present as completely as possible the details oftheir formulations and the associatedcomputing-time requirements.The thermal model described here simulateswet or dry, forward or reverse combustion in one, two, or three dimensions. The formulation allowsany number and identities of components and anynumber of chemical reactions, with reactants, products, and stoichiometry specified through input products, and stoichiometry specified through input data. SPEJ P. 533


2017 ◽  
Vol 17 (2) ◽  
pp. 279-284 ◽  
Author(s):  
Yuxiang Zhang ◽  
Eric Larose ◽  
Ludovic Moreau ◽  
Grégoire d’Ozouville

Locadiff, an innovative imaging technique based on diffuse waves, has recently been developed in order to image mechanical changes in heterogeneous, geological, or man-made materials. This manuscript reports the on-site application of Locadiff to locate several pre-existing cracks on an aeronautical wind tunnel made of pre-stressed concrete. Using 32 transducers working at ultrasonic frequencies (80–220 kHz) where multiple scattering occurs, we monitor during 15 min an area of 2.5 m×2.5 m of a 35-cm-thick wall. With the wind tunnel in its routine operation, structural changes around the cracks are detected, thanks to their closing or opening due to slight pressure changes. By mapping the density of such microstructure changes in the bulk of the material, locating three pre-existing cracks is properly performed in three dimensions.


2007 ◽  
Vol 15 (2) ◽  
pp. 121-130 ◽  
Author(s):  
F. Xu ◽  
R. A. Holt ◽  
E. C. Oliver ◽  
M. R. Daymond

2006 ◽  
Vol 519-521 ◽  
pp. 821-827 ◽  
Author(s):  
Éric Maire ◽  
J.C. Grenier ◽  
L. Babout

X-ray tomography allows the microstruture of aluminum alloys to be imaged non destructively in three dimensions (3D). This paper shows different examples of the use of this technique for the quantification of damage in model and industrial Al based materials. The model materials are used to setup the technique. The spherical shape of their inclusions makes it easy to compare the measurements with the prediction of standard model for damage. The industrial materials are characterized during in situ tensile but also ex situ bulging and plane strain tension tests. The respective contribution of initiation and growth of damage is measured separately and discussed. The 3D data are also used to quantify the anisotropy of the effect of damage.


2021 ◽  
Vol 118 (32) ◽  
pp. e2018976118
Author(s):  
Eva Shrestha ◽  
Jonathan B. Coulter ◽  
William Guzman ◽  
Busra Ozbek ◽  
Megan M. Hess ◽  
...  

Prostate adenocarcinoma is the second most commonly diagnosed cancer in men worldwide, and the initiating factors are unknown. Oncogenic TMPRSS2:ERG (ERG+) gene fusions are facilitated by DNA breaks and occur in up to 50% of prostate cancers. Infection-driven inflammation is implicated in the formation of ERG+ fusions, and we hypothesized that these fusions initiate in early inflammation-associated prostate cancer precursor lesions, such as proliferative inflammatory atrophy (PIA), prior to cancer development. We investigated whether bacterial prostatitis is associated with ERG+ precancerous lesions in unique cases with active bacterial infections at the time of radical prostatectomy. We identified a high frequency of ERG+ non–neoplastic-appearing glands in these cases, including ERG+ PIA transitioning to early invasive cancer. These lesions were positive for ERG protein by immunohistochemistry and ERG messenger RNA by in situ hybridization. We additionally verified TMPRSS2:ERG genomic rearrangements in precursor lesions using tricolor fluorescence in situ hybridization. Identification of rearrangement patterns combined with whole-prostate mapping in three dimensions confirmed multiple (up to eight) distinct ERG+ precancerous lesions in infected cases. We further identified the pathogen-derived genotoxin colibactin as a potential source of DNA breaks in clinical cases as well as cultured prostate cells. Overall, we provide evidence that bacterial infections can initiate driver gene alterations in prostate cancer. In addition, our observations indicate that infection-induced ERG+ fusions are an early alteration in the carcinogenic process and that PIA may serve as a direct precursor to prostate cancer.


2016 ◽  
Author(s):  
Geoff Fudenberg ◽  
Maxim Imakaev

AbstractDeciphering how the one-dimensional information encoded in a genomic sequence is read out in three-dimensions is a pressing contemporary challenge. Chromosome conformation capture (3C) and fluorescence in-situ hybridization (FISH) are two popular technologies that provide important links between genomic sequence and 3D chromosome organization. However, how to integrate views from 3C, or genome-wide Hi-C, and FISH is far from solved. We first discuss what each of these methods measure by reconsidering available matched experimental data for Hi-C and FISH. Using polymer simulations, we then demonstrate that contact frequency is distinct from average spatial distance. We show this distinction can create a seemingly-paradoxical relationship between 3C and FISH. Finally, we consider how the measurement of specific interactions between chromosomal loci might be differentially affected by the two technologies. Together, our results have implications for future attempts to cross-validate and integrate 3C and FISH, as well as for developing models of chromosomes.


Author(s):  
Daniel Ferreira Fidalgo ◽  
Eduardo Porfírio ◽  
Ana Maria Silva

O presente trabalho incide sobre a análise antropológica do espólio ósseo humano recuperado de 21 hipogeus do arqueossítio de Torre Velha 3 (TV3; São Salvador, Serpa), datados entre os meados e a segunda metade do II milénio a.C.. Dezasseis hipogeus são individuais, três duplos (uma inumação in situ com uma redução associada) e um triplo (enterramento duplo com uma redução associada) e dois contextos funerários inconclusivos. Todos os restos ósseos humanos foram recuperados da câmara funerária. Para além destes, um hipogeu continha um enterramento com uma redução associada na câmara e uma inumação primária na antecâmara. Destes sepulcros foram exumados 28 indivíduos, 22 adultos (11 do sexo feminino, nove do masculino e dois casos indeterminados), cinco não adultos e um em que não foi possível atribuir uma faixa etária. Nas inumações primárias e individuais, as oferendas cárneas encontram-se associadas a adultos de ambos os sexos. Por sua vez as cerâmicas e punções surgem somente em enterramentos do sexo feminino, com a excepção de um punção associado ao adulto do sexo masculino [2007]. Recorrendo à análise estatística de componentes principais, foi possível observar que as diferenças na morfologia dentária de TV3 em comparação com outras amostras da Pré-História recente Peninsular são mínimas, e podem ser explicadas por mudanças genéticas associadas a possíveis contactos e interações interregionais. Foram ainda identificados padrões de desgaste dentário atípico que sugerem o uso parafuncional do sistema mastigatório de adultos do sexo feminino. Relativamente à patologia oral, a incidência de lesões cariogénicas na amostra é de 5,85% (29/495), e afecta cerca de 57% dos indivíduos analisados (n=21). Estes valores são superiores à maioria das amostras comparadas do Neolítico Final/Calcolítico do actual território Português, mas semelhantes aos registados para outras comunidades da Idade do Bronze. New data on the Middle Bronze Age hypogea of Torre Velha 3 (Serpa): burial contexts and the study of the human osteological remains - The present work focuses on the anthropological analysis of the human remains exhumed from 21 hypogea of the archaeological site of Torre Velha 3 (TV3; São Salvador, Serpa), which is dated between the middle and second half of the II millennium B.C. Sixteen hypogea were individual, three double (one in situ burial with an associated reduction) and one triple (double burial with associated reduction) and two inconclusive funerary contexts. The human remains were collected unearthed from the chambers of the tombs. Besides these, one hypogeum displayed an in situ burial with an associated reduction in the chamber and other in situ burial in theantechamber. From these tombs were exhumed 28 individuals, 22 adults (11 females, nine males and 2 inconclusive), five non adults and one unknown. In primary and individual burials, meat offering were found in association with adults from both sexes. Ceramic vessels and awls are found only in female burials, with the exception of one awl found in association with the male adult [2007]. Using a principal component analyses, it was possible to observe that the differences in dental morphological traits found in TV3, in comparison with other samples from the Iberian Peninsula’s recent pre-history, are minimal and can be explained by genetic changes derived from possible inter-regional contacts and interactions. Some atypical dental wear patterns were also identified, mostly in adult females, and these suggest the parafunctional use of the masticatory system. Finally, the incidence of cariogenic lesions found is 5.85% (29/495), affecting around 57% of the individuals analysed (n=21). These values are higher than Late Neolithic/Chalcolithic samples from nowadays Portugal, but similar to the values found in Bronze Age samples.


2013 ◽  
Vol 31 (12) ◽  
pp. 2207-2212 ◽  
Author(s):  
D. Pokhotelov ◽  
S. von Alfthan ◽  
Y. Kempf ◽  
R. Vainio ◽  
H. E. J. Koskinen ◽  
...  

Abstract. A novel hybrid-Vlasov code, Vlasiator, is developed for global simulations of magnetospheric plasma kinetics. The code is applied to model the collisionless bow shock on scales of the Earth's magnetosphere in two spatial dimensions and three dimensions in velocity space retrieving ion distribution functions over the entire foreshock and magnetosheath regions with unprecedented detail. The hybrid-Vlasov approach produces noise-free uniformly discretized ion distribution functions comparable to those measured in situ by spacecraft. Vlasiator can reproduce features of the ion foreshock and magnetosheath well known from spacecraft observations, such as compressional magnetosonic waves generated by backstreaming ion populations in the foreshock and mirror modes in the magnetosheath. An overview of ion distributions from various regions of the bow shock is presented, demonstrating the great opportunities for comparison with multi-spacecraft observations.


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