High-oleic canola oil

2022 ◽  
pp. 89-108
Author(s):  
Michael N.A. Eskin ◽  
Diliara R. Iassonova ◽  
Curis B. Rempel
Keyword(s):  
2018 ◽  
Vol 108 (3) ◽  
pp. 594-602 ◽  
Author(s):  
Susan K Raatz ◽  
Zach Conrad ◽  
Lisa Jahns ◽  
Martha A Belury ◽  
Matthew J Picklo

ABSTRACT BACKGROUND High-oleic (HO) seed oils are being introduced as replacements for trans fatty acid (TFA)–containing fats and oils. Negative health effects associated with TFAs led to their removal from the US Generally Recognized As Safe list. HO oils formulated for use in food production may result in changes in fatty acid intake at population levels. Objectives The purposes of this study were to 1) identify major food sources of soybean oil (SO) and canola oil (CO), 2) estimate effects of replacing SO and CO with HO varieties on fatty acid intake overall and by age and sex strata, and 3) compare predicted intakes with the Dietary Reference Intakes and Adequate Intakes (AIs) for the essential fatty acids (EFAs) α-linolenic acid (ALA) and linoleic acid (LA). Design Food and nutrient intakes from NHANES waves 2007–2008, 2009–2010, 2011–2012, and 2013–2014 in 21,029 individuals aged ≥20 y were used to model dietary changes. We estimated the intake of fatty acid with the replacement of HO-SO and HO-CO for commodity SO and CO at 10%, 25%, and 50% and evaluated the potential for meeting the AI at these levels. RESULTS Each modeling scenario decreased saturated fatty acids (SFAs), although intakes remained greater than recommended for all age and sex groups. Models of all levels increased the intake of total monounsaturated fatty acids (MUFAs), especially oleic acid, and decreased the intake of total polyunsaturated fatty acids (PUFAs), particularly LA and ALA. Replacement of traditional with HO oils at 25–50% places specific adult age and sex groups at risk of not meeting the AI for LA and ALA. Conclusions The replacement of traditional oils with HO varieties will increase MUFA intake and reduce both SFA and PUFA intakes, including EFAs, and may place specific age and sex groups at risk of inadequate LA and ALA intake.


Metabolism ◽  
2006 ◽  
Vol 55 (3) ◽  
pp. 391-395 ◽  
Author(s):  
Iwona Rudkowska ◽  
Catherine E. Roynette ◽  
Dilip K. Nakhasi ◽  
Peter J.H. Jones

2016 ◽  
Vol 115 (6) ◽  
pp. 1012-1023 ◽  
Author(s):  
Shuaihua Pu ◽  
Peter Eck ◽  
David J. A. Jenkins ◽  
Philip W. Connelly ◽  
Benoît Lamarche ◽  
...  

AbstractFatty acid ethanolamides (FAE), a group of lipid mediators derived from long-chain fatty acids (FA), mediate biological activities including activation of cannabinoid receptors, stimulation of fat oxidation and regulation of satiety. However, how circulating FAE levels are influenced by FA intake in humans remains unclear. The objective of the present study was to investigate the response of six major circulating FAE to various dietary oil treatments in a five-period, cross-over, randomised, double-blind, clinical study in volunteers with abdominal obesity. The treatment oils (60 g/12 552 kJ per d (60 g/3000 kcal per d)) provided for 30 d were as follows: conventional canola oil, high oleic canola oil, high oleic canola oil enriched with DHA, flax/safflower oil blend and corn/safflower oil blend. Two SNP associated with FAE degradation and synthesis were studied. Post-treatment results showed overall that plasma FAE levels were modulated by dietary FA and were positively correlated with corresponding plasma FA levels; minor allele (A) carriers of SNP rs324420 in gene fatty acid amide hydrolase produced higher circulating oleoylethanolamide (OEA) (P=0·0209) and docosahexaenoylethanolamide (DHEA) levels (P=0·0002). In addition, elevated plasma DHEA levels in response to DHA intake tended to be associated with lower plasma OEA levels and an increased gynoid fat mass. In summary, data suggest that the metabolic and physiological responses to dietary FA may be influenced via circulating FAE. Genetic analysis of rs324420 might help identify a sub-population that appears to benefit from increased consumption of DHA and oleic acid.


2016 ◽  
Vol 10 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Claudia Loganes ◽  
Simonetta Ballali ◽  
Clara Minto

Together with olive and soybean, canola is one of the most important and diffuse oilseed crops. Due to high oleic acid and antioxidant contents, canola oil shows positive effects on cholesterol, glycemic control, blood pressure and cancer. For these reasons, canola oil can be considered an important food-resource: future scientific research is expected to provide further evidence on adoption of canola oil as a standard dietary choice in healthy subjects as well as a therapeutic strategy in disease treatment.


Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Kate J Bowen ◽  
Penny M Kris-Etherton ◽  
Sheila G West ◽  
Jennifer A Fleming ◽  
Philip W Connelly ◽  
...  

Introduction: Identifying dietary interventions for cardiometabolic disease prevention in individuals with metabolic syndrome is relevant to a significant portion of the population. Numerous studies have investigated the effects of canola oil on cardiovascular disease risk; however, no studies have compared canola oil diets to a control diet with a fatty acid composition characteristic of Western intakes in individuals with metabolic syndrome risk factors. The objectives of this study were to evaluate effects of canola oil, high-oleic acid canola oil (HOCO), and a control oil (blend of butter, safflower, coconut, and flaxseed oils formulated to represent a Western diet fatty acid profile) on lipids, lipoproteins, and apolipoproteins. Hypothesis: We tested the hypothesis that the two canola oil diets would elicit beneficial effects on the total lipid/lipoprotein profile compared to the Western (control oil) diet. Methods: In a multi-center, double blind, randomized, three-period crossover, controlled feeding clinical trial, 119 individuals with an increased waist circumference plus at least one additional metabolic syndrome risk factor consumed prepared isocaloric, weight maintenance diets containing canola oil [17.5% E from monounsaturated fatty acids (MUFA), 9.2% polyunsaturated fatty acids (PUFA), 6.6% saturated fatty acids (SFA)], HOCO (19.1% E from MUFA, 7.0% PUFA, 6.4% SFA), or control oil (11% E from MUFA, 10% PUFA, 12% SFA) for six-weeks each separated by 4-12 week washouts. The differences at the end of 42 days of feeding were tested. Results: The canola oil and HOCO resulted in lower endpoint total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), the TC: high-density lipoprotein-cholesterol (HDL-C) ratio, apolipoprotein (apo) B, the apoB: apoA1 ratio, and non-HDL-C compared to control oil ( P <0.0001 for treatment effect), with no differences between HOCO and canola oil for these parameters. Endpoint apoA1 did not significantly differ between the two canola oils and control, but was higher after the HOCO compared to canola oil (1.46 ± 0.02 g/L vs. 1.43 ± 0.02 g/L, P = 0.0462). There were no differences among the three diets in endpoint triglycerides or HDL-C. Conclusions: Incorporating canola or high-oleic acid canola oils into the diet improves blood lipids and lipoproteins compared to a contemporary Western diet in individuals with at least two criteria for metabolic syndrome.


2015 ◽  
Vol 238 (2) ◽  
pp. 231-238 ◽  
Author(s):  
Peter J.H. Jones ◽  
Dylan S. MacKay ◽  
Vijitha K. Senanayake ◽  
Shuaihua Pu ◽  
David J.A. Jenkins ◽  
...  

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Jyoti Sihag ◽  
Peter Jones

Abstract Objectives To elucidate the impact of diet on fatty acid ethanolamide (FAE) levels in seven different tissues/organs of male hamsters, with the hypothesis that dietary fatty acids (DFA) will act as precursors for FAE synthesis in golden Syrian male hamsters. Methods A two month feeding trial was performed, wherein hamsters (n = 105) were fed various dietary oil blends; namely, C + S, 25:75 corn oil: n9 safflower oil; F + S, 25:75 flaxseed oil: n6 safflower oil; H + DHA, 85:15 high oleic canola oil: docosahexaenoic acid; H + EPA, 85:15 high oleic canola oil: eicosapentaenoic acid; HOCO, high oleic canola oil; OO, olive oil; and RC, regular canola oil. Tissue fatty acid (FA) and FAE concentrations were assessed using GC-FID and UPLC-MS/MS, respectively. Results Results show that DFA directly influences tissue FA and FAE levels. After C18:1n9-enriched dietary treatments, marked increases (P < 0.05) were observed in duodenal C18:1n9 and oleoylethanolamide (OEA) concentrations. Overall, a weak negative association was observed between OEA concentrations and body weight (BW) at the endpoint, (r = –0.10216; P = 0.0070). Furthermore, among all tissues; namely, adipose tissue brown (ATB), adipose tissue white (ATW), brain, heart, intestine-duodenum (I-D), intestine-jejunum (I-J), and liver a negative correlation was observed between brain OEA concentrations and BW, (r = –0.22669; P = 0.0269). Conclusions DFA composition influences FA and FAE levels across all tissues. Furthermore, we summarize that brain transmits anorexic properties mediated via neuronal signalling which may contribute to the maintenance of healthy body weight and that the benefits of OEA can be enhanced by the inclusion of C18:1n9-enriched diets. Funding Sources The Natural Sciences and Engineering Research Council of Canada supported this research.


2019 ◽  
Vol 149 (3) ◽  
pp. 471-478 ◽  
Author(s):  
Kate J Bowen ◽  
Penny M Kris-Etherton ◽  
Sheila G West ◽  
Jennifer A Fleming ◽  
Philip W Connelly ◽  
...  

ABSTRACTBackgroundNovel oils high in monounsaturated fatty acids (MUFAs) and low in saturated fatty acids (SFAs) are an alternative to partially hydrogenated oils high in trans-unsaturated fatty acids. There is widespread use of high-MUFA oils across the food industry; however, limited knowledge of their cardiovascular impact exists.ObjectivesWe investigated the effects of diets containing canola oil, high-oleic acid canola oil (HOCO), and a control oil blend (diet formulated to emulate a Western fat profile) on lipids, lipoproteins, and apolipoproteins (apos), as secondary outcomes of the trial.MethodsIn a multi-center, double-blind, randomized, 3-period crossover, controlled feeding trial, men (n = 44) and women (n = 75) with a mean age of 44 y, mean body mass index (BMI; in kg/m2) of 31.7, and an increased waist circumference plus ≥1 metabolic syndrome criteria consumed prepared, weight-maintenance diets containing canola oil [17.5% MUFAs, 9.2% polyunsaturated fatty acids (PUFAs), 6.6% SFAs], HOCO (19.1% MUFAs, 7.0% PUFAs, 6.4% SFAs), or control oil (10.5% MUFAs, 10.0% PUFAs, 12.3% SFAs) for 6 wk with ≥4-wk washouts. Fasting serum lipids were assessed at baseline and 6 wk. Diet effects were examined using a repeated measures mixed model.ResultsCompared with the control, canola and HOCO diets resulted in lower endpoint total cholesterol (TC; −4.2% and −3.4%; P < 0.0001), LDL cholesterol (−6.6% and −5.6%; P < 0.0001), apoB (−3.7% and −3.4%; P = 0.002), and non-HDL cholesterol (−4.5% and −4.0%; P = 0.001), with no differences between canola diets. The TC:HDL cholesterol and apoB:apoA1 ratios were lower after the HOCO diet than after the control diet (−3.7% and −3.4%, respectively). There were no diet effects on triglyceride, HDL cholesterol, or apoA1 concentrations.ConclusionsHOCO, with increased MUFAs at the expense of decreased PUFAs, elicited beneficial effects on lipids and lipoproteins comparable to conventional canola oil and consistent with reduced cardiovascular disease risk in adults with central adiposity. This trial was registered at www.clinicaltrials.gov as NCT02029833.


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