Background:
Nanosuspensions are colloidal systems consisting of pure drug and stabilizers, without matrix or
lyophilized into a solid matrix. Nanosuspensions improve the solubility of the drug both in the aqueous and organic
phases. Nanosuspensions are also known as brick dust molecules, as they increase the dissolution of a system and improve
absorption.
Methods:
Extensive information related to nanosuspensions and its associated patents were collected using PubMed and
Google Scholar.
Results:
Over the last decade nanosuspensions have attracted tremendous interest in pharmaceutical research. It provides
unique features including, improved solubility, high drug loading capacity, and passive targeting. These particles are costeffective, simple, and have lesser side effects with minimal dose requirements. However, the stability of nanosuspensions
still warrants attention.
Conclusion:
Nanosuspensions plays a vital role in handling the numerous drug entities with difficult physico-chemical
characteristics such as solubility and can further aid with a range of routes that include nasal, transdermal, occular,
parenteral, pulmonary etc. This review highlights the relevance of nanosuspensions in achieving safe, effective and
targeted drug delivery.