Dietary supplementation with Forsythia suspensa extract during late gestation improves reproductive performance, colostrum composition, antioxidant status, immunoglobulin, and inflammatory cytokines in sows and newborn piglets

2020 ◽  
pp. 114700
Author(s):  
S.F. Long ◽  
D. Wu ◽  
T.F. He ◽  
X.S. Piao
Keyword(s):  
Inflammatory Cytokines ◽  
Reproductive Performance ◽  
Antioxidant Status ◽  
Dietary Supplementation ◽  
Late Gestation ◽  
Newborn Piglets ◽  
Forsythia Suspensa

scholarly journals PSIII-20 Dietary Forsythia suspensa extract supplementation in sows during late gestation improves reproductive performance, colostrum composition, antioxidant status, and immune function of sows and piglets

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 367-367
Author(s):  
Shenfei Long ◽  
Tengfei He ◽  
Di Wu ◽  
Xiangshu Piao
Keyword(s):  
Body Weight ◽  
Immune Function ◽  
Reproductive Performance ◽  
Antioxidant Status ◽  
Control Diet ◽  
Immunoglobulin A ◽  
Basal Diet ◽  
Late Gestation ◽  
Litter Weight ◽  
Forsythia Suspensa

Abstract This study aims to evaluate the effects of dietary Forsythia suspensa extract (FSE) supplementation in sows during late gestation on reproductive performance, colostrum composition, antioxidant status and immune function [NSFC 31772612]. Forty Yorkshire × Landrace gestating sows (average parity of 3.28 ± 0.61; average body weight of 240.16 ± 6.81 kg) were assigned to 2 treatments with 20 sows per treatment based on body weight, back fat thickness and parity. From d 85 of gestation to farrowing, sows were supplemented with a control diet (corn-soybean meal basal diet, CON), and a FSE diet (basal diet + 100 mg / kg FSE). The results showed that sows fed FSE had increased (P < 0.05) litter weight, fat and protein contents in colostrum compared with CON. Dietary FSE supplementation in sows could increase (P < 0.05) total antioxidant capacity and superoxide dismutase contents, and decrease (P < 0.05) the content of malondialdehyde in colostrum, and increase (P < 0.05) the contents of catalase and glutathione peroxidase in serum of their offspring compared with CON. Additionally, sows fed FSE could also increase (P < 0.05) the content of immunoglobulin A in serum of their offspring compared with CON. Sows fed FSE had decreased (P < 0.05) content of interleukin-6 (IL-6) and increased (P < 0.05) content of IL-10 in serum and colostrum of sows, and decreased (P < 0.05) contents IL-6 and IL-8 in serum of their offspring compared with CON. Sows fed FSE showed increased (P < 0.05) content of glucose in colostrum and decreased (P < 0.05) content of serum urea of their offspring compared with CON. In conclusion, dietary FSE supplementation in sows during late gestation could improve litter weight, colostrum fat and protein contents, antioxidant status, immunoglobulin, inflammatory cytokines of sows and piglets.

Dietary supplementation with N-carbamylglycinate (CGly) improved feed source proline absorption and reproductive performance in sows

2020 ◽  
Vol 11 (4) ◽  
pp. 3126-3133
Author(s):  
Dan Wan ◽  
YiKun Li ◽  
GuanYa Li ◽  
Xin Wu ◽  
DongMing Zhang ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
Dietary Supplementation ◽  
Late Gestation ◽  
Feed Source

Maternal dietary supplementation of N-carbamylglycinate (CGly) in late gestation sow is effective for improving their litter birth weights and sows’ glycine and proline profiles.

scholarly journals PSXIII-10 Dietary Forsythia suspensa extract supplementation improves reproductive performance, antioxidant status and immune function in lactating sows and suckling piglets

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 476-477
Author(s):  
Shenfei Long ◽  
Tengfei He ◽  
Di Wu ◽  
Xiangshu Piao
Keyword(s):  
Body Weight ◽  
Immune Function ◽  
Reproductive Performance ◽  
Antioxidant Status ◽  
Basal Diet ◽  
Villus Height ◽  
Forsythia Suspensa ◽  
Lactating Sows ◽  
Suckling Piglets ◽  
Mda Content

Abstract Lactating sows face various stresses, leading to poor reproductive performance and high mortality in piglets. Previous studies have demonstrated Forsythia suspensa extract (FSE) has antioxidant and antibacterial functions in broilers and piglets. However, rare researches focus on the effect of FSE in lactating sows. Therefore, this experiment was conducted to investigate dietary FSE supplementation on performance, antioxidant status and immunity in sows and piglets. 24 healthy Yorkshire × Landrace sows (average body weight of 234 ± 6.81 kg; average parity of 3.38 ± 0.61) were allotted into 2 dietary treatments with 12 sows per treatment based on parity, back fat thickness and body weight. Sows were fed a corn-soybean meal basal diet (CON), or a FSE diet (basal diet+100 mg/kg FSE) from d 107 of gestation until d 21 of lactation. Compared with CON, sows fed FSE showed decreased (P < 0.05) estrus interval, body weight loss from farrowing to weaning, and increased (P < 0.05) average daily gain from d 7 to 21 in piglet, as well as enhanced (P < 0.05) lactose, fat and protein contents on d 14, and IgA level on d 7 in milk. These sows also had increased (P < 0.05) T-AOC content, reduced (P < 0.05) MDA content in placenta, and improved (P < 0.05) serum T-AOC, GSH-Px and CAT contents at farrowing and weaning. Their piglets behaved higher (P < 0.05) SOD content and lower (P < 0.05) MDA content in serum on d 0, 7, 14, as well as increased (P < 0.05) serum T-AOC and GSH-Px contents on d 21. These piglets also had higher villus height and villus height to crypt depth ratio in jejunum on d 21 compared with CON. In conclusion, dietary FSE supplementation improved performance, antioxidant status and immune function in lactating sows and suckling piglets.

scholarly journals Responses of Vaginal Microbiota to Dietary Supplementation with Lysozyme and its Relationship with Rectal Microbiota and Sow Performance from Late Gestation to Early Lactation

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 593
Author(s):  
Shengyu Xu ◽  
Yanpeng Dong ◽  
Jiankai Shi ◽  
Zimei Li ◽  
Lianqiang Che ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
Control Diet ◽  
Dietary Supplementation ◽  
16S Rrna Gene Sequencing ◽  
Interleukin 10 ◽  
Fecal Microbiota ◽  
Vaginal Microbiota ◽  
Late Gestation ◽  
Rrna Gene ◽  
Early Lactation

This study was conducted to evaluate the effects of dietary lysozyme (LZM) supplementation on the vaginal microbiota, as well as the relationship between vaginal microbiota and the fecal microbiota of rectum and the reproductive performance of the sow. A total of 60 Yorkshire × Landrace sows (3–6 of parity) were arranged from day 85 of gestation to the end of lactation in a completely randomized design with three treatments (control diet, control diet + lysozyme 150 mg/kg, control diet + lysozyme 300 mg/kg). The results showed that sows fed with lysozyme increased serum interleukin-10 (IL-10, p < 0.05) on day 7 of lactation. The vaginal microbiota varied at different taxonomic levels with LZM supplementation by 16S rRNA gene sequencing. The most representative changes included a decrease in Tenericutes, Streptococcus, Bacillus and increase in Bacteroidetes, Actinobacteria, Enterococcus, and Lactobacillus (p < 0.05). There were 777 OTUs existing in both, vaginal and fecal microbiota. The addition of LZM also decreased the abundance of Tenericutes (p < 0.05) in the vagina and feces. The changes in the microbiota were correlated in some cases positively with the performance of the sow, for example, Bacillus in feces was positively correlated with the neonatal weight (p < 0.05). These results indicate that the addition of lysozyme to the diet of sow during perinatal period promote the change of vaginal bacterial community after farrowing. The variations in vaginal microbiota are also associated with the changes in the fecal microbiology of the rectum and the reproductive performance of the sow. Therefore, it is concluded that dietary supplementation with lysozyme in sows in late gestation stage until early lactation, is beneficial to establish vaginal microbiota that seems to promote maternal health and reproductive performance.

scholarly journals Effects of Melatonin Supplementation during Pregnancy on Reproductive Performance, Maternal–Placental–Fetal Redox Status, and Placental Mitochondrial Function in a Sow Model

Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1867
Author(s):  
Xie Peng ◽  
Xuelin Cai ◽  
Jian Li ◽  
Yingyan Huang ◽  
Hao Liu ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Reproductive Performance ◽  
Mitochondrial Function ◽  
Pregnancy Complications ◽  
Antioxidant Status ◽  
Control Diet ◽  
Dietary Supplementation ◽  
Underlying Mechanism ◽  
Redox Status ◽  
Mrna Levels

Melatonin (MT) is a bio-antioxidant that has been widely used to prevent pregnancy complications, such as pre-eclampsia and IUGR during gestation. This experiment evaluated the impacts of dietary MT supplementation during pregnancy on reproductive performance, maternal–placental–fetal redox status, placental inflammatory response, and mitochondrial function, and sought a possible underlying mechanism in the placenta. Sixteen fifth parity sows were divided into two groups and fed each day of the gestation period either a control diet or a diet that was the same but for 36 mg of MT. The results showed that dietary supplementation with MT increased placental weight, while the percentage of piglets born with weight < 900 g decreased. Meanwhile, serum and placental MT levels, maternal–placental–fetal redox status, and placental inflammatory response were increased by MT. In addition, dietary MT markedly increased the mRNA levels of nutrient transporters and antioxidant-related genes involved in the Nrf2/ARE pathway in the placenta. Furthermore, dietary MT significantly increased ATP and NAD+ levels, relative mtDNA content, and the protein expression of Sirt1 in the placenta. These results suggested that MT supplementation during gestation could improve maternal–placental–fetal redox status and reproductive performance by ameliorating placental antioxidant status, inflammatory response, and mitochondrial dysfunction.

scholarly journals Dietary Supplementation with Natural Extracts Mixture: Effects on Reproductive Performances, Blood Biochemical and Antioxidant Parameters in Rabbit Does

2020 ◽  
Vol 20 (2) ◽  
pp. 565-578 ◽  
Author(s):  
Francesco Vizzarri ◽  
Sara Chiapparini ◽  
Carlo Corino ◽  
Donato Casamassima ◽  
Marisa Palazzo ◽  
...  
Keyword(s):  
Reproductive Cycle ◽  
Reproductive Performance ◽  
Antioxidant Status ◽  
Control Diet ◽  
Dietary Supplementation ◽  
Dietary Treatment ◽  
Hdl Cholesterol ◽  
Sampling Time ◽  
Brown Seaweeds ◽  
Natural Extracts

AbstractThe present study evaluates the effects of natural extracts on reproductive performance, haematochemical parameters, and antioxidant status of rabbit does. A total of sixty New Zealand White second parity does were divided into three groups: the first group was fed a control diet (CON), the second (T1) and the third groups (T2) were fed the same diet supplemented with prebiotic polysaccharides from brown seaweeds (Laminaria spp.) plus phenolic acid, hydroxycinnamic acids, tannins, and flavonoids from plant extracts (0.3% and 0.6%, respectively). The trial was conducted for two consecutive reproductive cycles (75 days). Reproductive performance was recorded. Blood samples were collected before the first insemination, 10 d after the first kindling, and 10 d after the second one. At the first reproductive cycle, productive parameters were negatively affected (P<0.05) by a high dosage of the dietary supplement (T2 group). At the second reproductive cycle, no differences (P>0.05) between dietary treatments on reproductive and productive performances were observed. Bilirubin was affected by dietary treatment (P<0.001) and decreased in relation to sampling time (P<0.001). The HDL cholesterol decreased by dietary treatment (P<0.01). All the plasma antioxidant markers were positively affected (P<0.001) by dietary supplementation and sampling time. No previous study has reported the effects of brown seaweeds and polyphenols on rabbit does and the present data shows that this natural extract supplement improved the antioxidant status of rabbit does.

scholarly journals Phytogenic actives supplemented in hyperprolific sows: effects on maternal transfer of phytogenic compounds, colostrum and milk features, performance and antioxidant status of sows and their offspring, and piglet intestinal gene expression

2020 ◽  
Vol 98 (1) ◽  
Author(s):  
David Reyes-Camacho ◽  
Ester Vinyeta ◽  
Jose Francisco Pérez ◽  
Tobias Aumiller ◽  
Lourdes Criado ◽  
...  
Keyword(s):  
Gene Expression ◽  
Volatile Compounds ◽  
Litter Size ◽  
Antioxidant Status ◽  
Digestive Enzyme ◽  
Well Being ◽  
Late Gestation ◽  
Maternal Transfer ◽  
Newborn Piglets ◽  
Suckling Piglets

Abstract Phytogenic actives (PA) are plant-derived natural bioactive compounds that may promote livestock health and well-being, as well as improve growth performance and production efficiency. The current study aims to evaluate their effects on sows and their offspring. Eighty-one hyperprolific sows (up to parity 7) were assigned to 3 experimental treatments. Control sows were offered a nonsupplemented diet during gestation and lactation, and treated sows were fed the control diet supplemented with 1 g/kg of a blend of PA (BPA) in lactation (L) or during gestation and lactation (GL). An evaluation was made of placental and milk maternal transfer of these BPA and colostrum–milk features, sows and piglets antioxidant status, reproductive performance (litter size), body weight (BW) changes, weaning-estrus interval, and litter performance. Finally, piglet´s jejunum gene expression was measured. The BPA supplementation during gestation (GL) increased the number of piglets born alive (P = 0.020) and reduced (P &lt; 0.05) the newborn piglets BW, while there were no differences among treatments on the suckling (day 20) and weaned (day 7) piglets BW (P &gt; 0.05). Dietary phytogenic volatile compounds reached GL placental fluid, and milk of L and GL sows (P &lt; 0.05). Moreover, colostrum protein in GL and milk fat content in L and GL were increased (P &lt; 0.05). Milk of GL showed inhibitory activity against Bacillus subtilis and Staphylococcus aureus (P &lt; 0.05). Antioxidant status of GL sows showed an enhanced (P &lt; 0.05) of catalase (CAT) and total antioxidant capacity levels at early gestation (day 35), whereas higher levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) enzymes at late gestation (day 110). Likewise, GL newborn piglets showed higher CAT levels, whereas both CAT and SOD levels in suckling piglets, as well as CAT, SOD, and GSH-Px in weaned piglets, were increased in L and GL (P &lt; 0.05). Jejunum messenger ribonucleic acid abundance of suckling piglets in L and GL groups showed overexpression of barrier function MUC2, digestive enzyme IDO, and immune response PPARGC-α, TNF-α, TGF-β1, and IL-10 genes (P &lt; 0.05). In conclusion, dietary BPA supplementation in hyperprolific sows increased the litter size (born alive) and improved the composition and bioactivity of colostrum and milk, besides, modified the antioxidant status of sows and their offspring, as well as the suckling piglets gut health gene expression. Several BPA volatile compounds were prenatal and postnatal maternally transferred (placental fluid and milk).

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