Effects of Physical Exercise on Plasma Levels of Brain-Derived Neurotrophic Factor and Depressive Symptoms in Elderly Women—A Randomized Clinical Trial

2013 ◽  
Vol 94 (8) ◽  
pp. 1443-1450 ◽  
Author(s):  
Daniele S. Pereira ◽  
Bárbara Z. de Queiroz ◽  
Aline S. Miranda ◽  
Natália P. Rocha ◽  
Diogo C. Felício ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Depressive Symptoms ◽  
Physical Exercise ◽  
Randomized Clinical Trial ◽  
Neurotrophic Factor ◽  
Plasma Levels ◽  
Elderly Women ◽  
Brain Derived Neurotrophic Factor

scholarly journals Effects of Music Aerobic Exercise on Depression and Brain-Derived Neurotrophic Factor Levels in Community Dwelling Women

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Shu-Hui Yeh ◽  
Li-Wei Lin ◽  
Yu Kuan Chuang ◽  
Cheng-Ling Liu ◽  
Lu-Jen Tsai ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Aerobic Exercise ◽  
Randomized Clinical Trial ◽  
Neurotrophic Factor ◽  
Comparison Group ◽  
Brain Derived Neurotrophic Factor ◽  
Demographic Characteristics ◽  
Community Dwelling ◽  
Depression Symptoms ◽  
Middle Aged

A randomized clinical trial was utilized to compare the improvement of depression and brain-derived neurotrophic factor (BDNF) levels between community women with and without music aerobic exercise (MAE) for 12 weeks. The MAE group involved 47 eligible participants, whereas the comparison group had 59 participants. No significant differences were recorded in the demographic characteristics between the participants in the MAE group and the comparison group. Forty-one participants in the MAE group and 26 in the comparison group completed a pre- and posttest. The MAE group displayed significant improvement in depression scores (p= 0.016), decreased depression symptoms in crying (p= 0.03), appetite (p= 0.006), and fatigue (p= 0.011). The BDNF levels of the participants significantly increased after the 12-week MAE (p= 0.042). The parallel comparison group revealed no significant changes in depression scores or BDNF levels. In summary, the 12-week MAE had a significant impact on the enhancement of BDNF levels and improvement of depression symptoms. Middle-aged community women are encouraged to exercise moderately to improve their depression symptoms and BDNF levels.

scholarly journals Nutritional intervention and functional exercises improve depression, loneliness and quality of life in elderly women with sarcopenia: a randomized clinical trial

2020 ◽  
Vol 33 ◽  
Author(s):  
Hudson Azevedo Pinheiro ◽  
Vera Regina Cerceau ◽  
Leonardo Costa Pereira ◽  
Silvana Schwerz Funghetto ◽  
Ruth Losada de Menezes
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Depressive Symptoms ◽  
Randomized Clinical Trial ◽  
Functional Group ◽  
Elderly Women ◽  
Nutritional Intervention ◽  
Control Group ◽  
Functional Exercise

Abstract Introduction: Loneliness interferes with the eating habits and functionality of the elderly, compromising their quality of life. Objective: This study aimed to evaluate the effects of eating and performing functional group-based exercises on depressive symptoms, loneliness and quality of life in patients with sarcopenia treated at a public health service. Method: This is a randomized clinical trial with a convenience sample of elderly women with sarcopenia according to the European Work Group of Sarcopenia on Older People (EWGSOP), divided into three groups of 20 subjects each: a control group (CG), functional exercise group (FEG), monitored using the Home-based Older People’s Exercise (HOPE) program, and functional exercise and nutritional intervention group (NIG), which in addition to HOPE, received pre-training fruit juice (fast-absorbing carbohydrates) and post-training banana smoothie reinforced with peanut (leucine). These groups met twice a week for 12 weeks, the control group (CG) received health guidance at weekly meetings for 12 weeks. The results of the interventions were analyzed using the geriatric depression scale and UCLA loneliness scale, and quality of life using the EQ-5D. Results: Significant post-intervention differences were observed in the NIG group in depressive (p=0.008) and loneliness symptoms (0.04) and quality of life (0.009), demonstrating the effects of group exercise and eating as a social activity. Conclusion: Nutritional intervention and functional group-based exercises were effective at minimizing depressive symptoms, social isolation, and improving the quality of life of elderly women with sarcopenia.

scholarly journals Physical Exercise Increased Brain-Derived Neurotrophic Factor in Elderly Population with Depression

2019 ◽  
Vol 7 (13) ◽  
pp. 2057-2061 ◽  
Author(s):  
Fauziah Nuraini Kurdi ◽  
Rostika Flora
Keyword(s):  
Physical Exercise ◽  
Neurotrophic Factor ◽  
Elderly Population ◽  
Elderly Women ◽  
Brain Derived Neurotrophic Factor ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Bdnf Level ◽  
Depression Group ◽  
Depressive Episodes

BACKGROUND: Depression is very common in the elderly population. Physical exercise is one of the non-pharmacological procedures that promise to be a solution to improve the severity of depression. Brain-Derived Neurotrophic Factor (BDNF) plays a role in maintaining the survival of neuronal cells and in the regulation of synapse plasticity, affecting serotonin production in the hippocampus and thus the depressive symptoms. AIM: This study aimed to assess the role of physical exercise in affecting BDNF levels in elderly with depression. METHODS: Thirty-five elderly women (age ≥ 50 years) with depressive episodes based on Diagnostic and Statistical Manual of Mental Disorders (DSM)-V criteria were enrolled as treatment group, and 35 elderly women without depressive episodes were enrolled as control group, and underwent physical exercise in the form of treadmill with a speed of 6 km/h for 15 minutes. Physical exercise was carried out once a day for 28 days. As much as 1 ml of blood from the study, subjects were obtained from the cubital vein before the exercise commenced. Brain-Derived Neurotrophic Factor (BDNF) serum level was assessed by Enzyme-Linked Immunosorbent Assay (ELISA). Data were presented in the form of mean ± SD. An independent T-test was used to test levels after exercise in the depression group compared to the non-depression group. RESULTS: Pre-exercise BDNF levels in the depression group were lower than the group of elderly without depression. Physical exercise increased BDNF production in both elderly groups with and without depression. In the depression group, the increasing percentage of BDNF level was higher compared to non-depressive elderly. CONCLUSION: The increasing percentage of BDNF level was found to be higher in depressive elderly performing physical exercise. Physical exercise may be beneficial in supporting the therapy of elderly with depression.

Dyslipidemia influences the effect of physical exercise on inflammatory markers on obese women in post-menopause: A randomized clinical trial

2021 ◽  
pp. 111355
Author(s):  
Piero Biteli ◽  
Sandra Maria Barbalho ◽  
Cláudia Rucco Penteado Detregiachi ◽  
Jesselina Francisco dos Santos Haber ◽  
Eduardo Federighi Baisi Chagas
Keyword(s):  
Clinical Trial ◽  
Physical Exercise ◽  
Randomized Clinical Trial ◽  
Inflammatory Markers ◽  
Obese Women ◽  
Post Menopause
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