Poly (vinyl alcohol) (PVA) hydrogel incorporated with Ag/TiO2 for rapid sterilization by photoinspired radical oxygen species and promotion of wound healing

2019 ◽  
Vol 494 ◽  
pp. 708-720 ◽  
Author(s):  
Jiameng Wang ◽  
Chao Zhang ◽  
Yongqiang Yang ◽  
Ailan Fan ◽  
Ruifang Chi ◽  
...  
Keyword(s):  
Wound Healing ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Oxygen Species ◽  
Radical Oxygen Species ◽  
Pva Hydrogel

scholarly journals Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Cellular Adhesion ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Hybrid Nanofibers

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.

scholarly journals Linear Dynamic Viscoelasticity of Dual Cross-Link Poly(Vinyl Alcohol) Hydrogel with Determined Borate Ion Concentration

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 71
Author(s):  
Takuro Taniguchi ◽  
Kenji Urayama
Keyword(s):  
Vinyl Alcohol ◽  
Ion Concentration ◽  
Poly Vinyl Alcohol ◽  
Relaxation Dynamics ◽  
Cross Link ◽  
Dynamic Viscoelasticity ◽  
Linear Dynamic ◽  
Cross Links ◽  
Pva Gel ◽  
Pva Hydrogel

We investigated the linear dynamic viscoelasticity of dual cross-link (DC) poly(vinyl alcohol) (PVA) (DC-PVA) hydrogels with permanent and transient cross-links. The concentrations of incorporated borate ions to form transient cross-links in the DC-PVA hydrogels (CBIN) were determined by the azomethine-H method. The dynamic viscoelasticity of the DC-PVA hydrogel cannot be described by a simple sum of the dynamic viscoelasticity of the PVA gel with the same permanent cross-link concentration and the PVA aqueous solution with the same borate ion concentration (CB = CBIN) as in the DC-PVA gel. The DC-PVA hydrogel exhibited a considerably higher relaxation strength, indicating that the introduction of permanent cross-links into temporary networks increases the number of viscoelastic chains with finite relaxation times. In contrast, the relaxation frequency (ωc) (given by the frequency at the maximum of loss modulus) for the DC-PVA hydrogel was slightly lower but comparable to that for a dilute PVA solution with the same CB. This signifies that the relaxation dynamics of the DC-PVA hydrogels is essentially governed by the lifetime of an interchain transient cross-link (di-diol complex of boron). The effect of permanent cross-linking on the relaxation dynamics was observed in the finite broadening of the relaxation-time distribution in the long time region.

scholarly journals Evaluation of PVA/dextran/chitosan hydrogel for wound dressing

2019 ◽  
Vol 38 (1-2) ◽  
pp. 15-30 ◽  
Author(s):  
Shin-Ping Lin ◽  
Kai-Yin Lo ◽  
Tien-Ni Tseng ◽  
Jui-Ming Liu ◽  
Ting-Yu Shih ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Wound Healing ◽  
Wound Dressing ◽  
Antimicrobial Property ◽  
High Water ◽  
Poly Vinyl Alcohol ◽  
High Water Content ◽  
Chitosan Hydrogel ◽  
Proliferation Ability ◽  
Pva Hydrogel

Developing a multiple functional wound dressing suitable for different stages of wound healing is important for patients with special wound such as burn or decubital ulcers. In this study, poly (vinyl alcohol) (PVA), dextran, and chitosan are integrated to produce ideal wound dressing where glutaraldehyde (GA) is used as the cross-linker. The result demonstrated that 6% PVA hydrogel with 0.25% chitosan was found to provide antimicrobial ability. The PVA/chitosan hydrogel combined with 4% dextran utilizing GA cross-linking also presents the high cell proliferation ability, which suggests that the hydrogel is potential as a wound dressing. In the following physical analyses, the addition of chitosan and dextran appeared to promote the thermostability, mechanical properties, water retention, and moisturizing ability in the PVA hydrogel. In conclusion, the PVA/chitosan/dextran hydrogel has promising potential such as high water content, antimicrobial property, and well cell proliferation, which can be applied to wound healing application.

Wear Reduction by Functional Protein Boundary Film on Poly(Vinyl Alcohol) Hydrogel

2005 ◽  
Author(s):  
K. Nakashima ◽  
Y. Sawae ◽  
T. Murakami
Keyword(s):  
Vinyl Alcohol ◽  
Film Formation ◽  
Glass Plate ◽  
Poly Vinyl Alcohol ◽  
Functional Protein ◽  
Adsorbed Film ◽  
Adsorption Condition ◽  
Boundary Film ◽  
Joint Prostheses ◽  
Pva Hydrogel

Poly(vinyl alcohol) (PVA) hydrogel is a candidate material for artificial cartilage of joint prostheses. From previous researches [1–4] it is shown that the wear of PVA hydrogel depends on the concentration of proteins in lubricants. Therefore it is considered that the adsorbed film formation by protein of albumin or γ-globulin influences upon the wear grade of PVA hydrogel. The remaining film of proteins on the glass plate was observed in fluorescence microscope. The adsorption condition of albumin and γ-globulin was different. The adsorbed film with effective reduction of the wear showed cooperative stratification of albumin and γ-globulin, but the condition of increased the wear showed separation of albumin and γ-globulin. Consequently, to reduce the wear of PVA hydrogel, cooperative stratification layers are effective.

Versatile poly(vinyl alcohol)/clay physical hydrogels with tailorable structure as potential candidates for wound healing applications

2020 ◽  
Vol 109 ◽  
pp. 110395 ◽  
Author(s):  
Simona Morariu ◽  
Maria Bercea ◽  
Luiza Madalina Gradinaru ◽  
Irina Rosca ◽  
Mihaela Avadanei
Keyword(s):  
Wound Healing ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol

Fabrication and characterization of phlorotannins/poly (vinyl alcohol) hydrogel for wound healing application

2017 ◽  
Vol 29 (7-9) ◽  
pp. 972-983 ◽  
Author(s):  
Hyeon-Ho Park ◽  
Seok-Chun Ko ◽  
Gun-Woo Oh ◽  
Soo-Jin Heo ◽  
Do-Hyung Kang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Fabrication And Characterization

scholarly journals Physico-chemical characteristics of gamma irradiation crosslinked poly(vinyl alcohol)/magnetite ferrogel composite

2014 ◽  
Vol 68 (6) ◽  
pp. 743-753 ◽  
Author(s):  
Milena Marinovic-Cincovic ◽  
Aleksandra Radosavljevic ◽  
Jelena Krstic ◽  
Jelena Spasojevic ◽  
Natasa Bibic ◽  
...  
Keyword(s):  
Gamma Irradiation ◽  
Vinyl Alcohol ◽  
Magnetic Particles ◽  
Heating Temperature ◽  
Crosslinking Agent ◽  
Poly Vinyl Alcohol ◽  
Chemical Characteristics ◽  
Physico Chemical ◽  
Soft Actuators ◽  
Pva Hydrogel

Magnetic field sensitive gels, ferrogels are new promising class of hydrogels. The coupling of hydrogels and magnetic particles has potential application in soft actuators such as artificial muscles or for hyperthermia application. Here a composite of magnetite particles (Fe3O4) and poly(vinyl alcohol) (PVA) hydrogel is developed using gamma irradiation as a crosslinking agent. PVA and Fe3O4 were chosen because of their well-established biocompatibility, radiation crosslinking potential (PVA), mild magnetic properties and the Curie point near desired heating temperature range (Fe3O4). Physico-chemical characteristics of these systems show the effect of the presence of particles in the process of radiation-induced crosslinking. Obtained PVA/Fe3O4 ferrogel composite has greater swelling capacity, activation energy of dehydration and dehydration rate compared to PVA hydrogel, crosslinked under the same conditions.

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