EFFECT OF VIDEO EDUCATION ABOUT POTENTIAL TREATMENT-RELATED SIDE-EFFECTS ON PATIENT`S ANXIETY, DEPRESSION, AND DISTRESS LEVEL

Chronic pain is a common condition that seriously affects the quality of human life with variable etiology and complicated symptoms; people who suffer from chronic pain may experience anxiety, depression, insomnia, and other harmful emotions. Currently, chronic pain treatments are nonsteroidal anti-inflammatory drugs and opioids; these drugs are demonstrated to be insufficient and cause severe side effects. Therefore, research into new therapeutic strategies for chronic pain is a top priority. In recent years, stem cell transplantation has been demonstrated to be a potent alternative for the treatment of chronic pain. Mesenchymal stem cells (MSCs), a type of pluripotent stem cell, exhibit multi-directional differentiation, promotion of stem cell implantation, and immune regulation; they have also been shown to exert analgesic effects in several chronic pain models. Exosomes produced by MSCs have been demonstrated to relieve painful symptoms with fewer side effects. In this review, we summarize the therapeutic use of MSCs in various chronic pain studies. We also discuss ways to enhance the treatment effect of MSCs. We predict in the future, cell-free therapies for chronic pain will develop from exosomes secreted by MSCs.

Download Full-text

Malfunction in GABA and Glutamate as Pathways to Depression: A Review of the Evidence

Clinical Medicine Therapeutics ◽

10.4137/cmt.s3481 ◽

2009 ◽

Vol 1 ◽

pp. CMT.S3481 ◽

Cited By ~ 2

Author(s):

Christopher F Sharpley

Keyword(s):

Experimental Data ◽

Side Effects ◽

Disease Burden ◽

Potential Treatment ◽

Pharmacological Treatments ◽

Neurotransmitter Systems ◽

Antidepressant Medications ◽

Depressed Patients ◽

Few Data

With nearly one fifth of the population experiencing depression sometime during their lives, plus the recent finding that depression rivals smoking in its association with mortality, the search for effective pharmacological treatments for depression remains urgent. However, despite this heavy disease burden upon society, the various waves of antidepressants developed in the last 40 years have shown significant side effects and little specific efficacy over placebo. One potential treatment may be via re-establishment of glutamate and GABA neurotransmitter systems that have been shown to malfunction in depressed patients. The literature describing possible causal links between GABA and/or glutamate malfunction and depression is reviewed, plus those studies which provide experimental data to confirm this hypothesis. While there is plausible support for the links between malfunction of these neurotransmitters and depression, few data exist yet regarding development of effective antidepressant medications based upon these findings.

Download Full-text

Depression and internet addiction: Correlation and treatment approaches

European Psychiatry ◽

10.1016/s0924-9338(11)73898-6 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 2195-2195 ◽

Cited By ~ 3

Author(s):

M. Stojakovic

Keyword(s):

Depressive Symptoms ◽

Side Effects ◽

Internet Addiction ◽

Symptom Severity ◽

The Internet ◽

Behavioral Characteristics ◽

Potential Treatment ◽

Treatment Approaches ◽

Symptoms Of Depression ◽

Use Of Internet

IntroductionWith increasing use of Internet in everyday life there is the risk of developing Internet dependency that can be correlated with depression. Is the internet an antidepressant or Internet addiction often causes mood-altering side effects?ObjectivesThe focus is to examine correlation between depression and Internet addiction, as well as potential treatment approaches.AimsThe aim of the study was to evaluate treatment approaches and the correlation between depression and Internet addiction(IA) by use of Telepsychiatric service.MethodsA total of 100 Bosnian clients were studied. Internet Addiction Test (IAT), Beck Depression Inventory (BDI), and the Zung Depression Inventory (ZDI) was used, by Telepsychiatric service, to assess state measures of symptom severity. First, they were evaluated for their severity of Internet addiction with consideration of their behavioral characteristics and their primary purpose for computer use by IAT. Second, we investigated Depression by Telepsychiatry service with BDI and ZDI scale. Third, we investigated correlations between depression and Internet addiction.ResultsThe symptoms of IA had been founded at 59% and 41% of patients had no IA. Symptoms of depression had been found at 45% patients. Internet addiction was significantly associated with depressive symptoms; IA and depression had been found at 41% patients (P < 0.01).ConclusionsThis study reveals a significant association between Internet addiction and depressive symptoms.

Download Full-text

Risperidone and escitalopram co-administration: A potential treatment of schizophrenia symptoms with less side effects

Pharmacological Reports ◽

10.1016/j.pharep.2016.09.010 ◽

2017 ◽

Vol 69 (1) ◽

pp. 13-21 ◽

Cited By ~ 5

Author(s):

Katarzyna Kamińska ◽

Karolina Noworyta-Sokołowska ◽

Alexandra Jurczak ◽

Anna Górska ◽

Zofia Rogóż ◽

...

Keyword(s):

Side Effects ◽

Potential Treatment

Download Full-text

Transdermal Administration of Aqueous Pregabalin Solution as a Potential Treatment Option for Patients with Neuropathic Pain to Avoid Central Nervous System-Mediated Side Effects

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.b14-00278 ◽

2014 ◽

Vol 37 (11) ◽

pp. 1816-1819 ◽

Cited By ~ 2

Author(s):

Hiroshi Fukasawa ◽

Hideaki Muratake ◽

Marina Nagae ◽

Kiyoshi Sugiyama ◽

Koichi Shudo

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Neuropathic Pain ◽

Side Effects ◽

Treatment Option ◽

Potential Treatment ◽

Transdermal Administration

Download Full-text

Application of hypnosis in psychOncology: A review of the literature

Análise Psicológica ◽

10.14417/ap.1859 ◽

2021 ◽

Vol 39 (2) ◽

pp. 263-275

Author(s):

Sónia Remondes-Costa ◽

Filipa Magalhães ◽

Inês Martins ◽

André Louro ◽

Martim Santos ◽

...

Keyword(s):

Side Effects ◽

Cancer Patients ◽

Web Of Science ◽

Controlled Trials ◽

Review Of The Literature ◽

Inclusion Criteria ◽

Cancer Disease ◽

Pain Anxiety ◽

Randomized Controlled ◽

Anxiety Depression

Hypnosis is useful for multiple somatic and psychological disorders, particularly cancer disease-related issues. In fact, the literature points out that hypnosis is effective in helping patients deal with aspects disease related, as well as in reducing the side effects of treatment. This review of the literature aims to summarize and assess the evidence of the usefulness of hypnosis in cancer patients and was conducted based on articles published between 2012 and 2019. The databases used were: B-on, SciELO, MEDLINE, and Web of Science. Randomized controlled trials and non-randomized studies were assessed. Among 837 studies identified, nine met the inclusion criteria and were selected. The studies were consensual to the effectiveness of hypnosis in reducing a set of symptoms in cancer patients, mainly pain, anxiety, depression, fatigue, and insomnia. However, several methodological limitations were identified. The practice of hypnosis is related to a significant number of techniques and approaches that differ from each other, thus compromising the interpretation and generalization of its effects. This review updates the evidence and suggests that the study of the efficacy of hypnosis in cancer patients is still limited. Further research into the effectiveness and acceptability of hypnosis for cancer patients is recommended.

Download Full-text

Integrative Treatments

10.1093/med/9780199392742.003.0038 ◽

2017 ◽

Author(s):

Cheryl Gore-Felton ◽

Lawrence McGlynn ◽

Andrei Kreutzberg ◽

David Spiegel

Keyword(s):

Quality Of Life ◽

Clinical Practice ◽

Side Effects ◽

Integrative Medicine ◽

Symptom Management ◽

Self Management ◽

Improve Quality ◽

Somatic Disorders ◽

Anxiety Depression

Many individuals seek relief from symptoms associated with HIV infection through the use of integrative medicine. Symptoms include neuropsychiatric problems such as anxiety, depression, cognitive dysfunction, and headaches, as well as somatic disorders related to viral infection and immunodysregulation, such as fatigue, diarrhea, and cardiovascular problems. As antiretroviral treatments have become increasingly effective, symptom management with minimal side effects has become more important. A variety of integrative treatments, including botanicals, vitamins, minerals, probiotics, and herbs, have been utilized, and mind–body approaches such as mindfulness, hypnosis, and movement therapy have been found to reduce symptoms and improve quality of life. This chapter examines widely used integrative medicine approaches to alleviating distressing HIV-related symptoms. Implications for clinical practice are discussed. Integrative approaches emphasize self-management of symptoms and are widely sought after and accepted, even by patients who resist other forms of medical treatment.

Download Full-text

A Short Communication on CURCUMIN- A Golden Spice in Treating COVID

International Journal of Advanced Research in Science, Communication and Technology ◽

10.48175/ijarsct-798 ◽

2021 ◽

pp. 118-121

Author(s):

Ekta Khare ◽

Sandeep Pandey ◽

Ritesh Kumar

Keyword(s):

Side Effects ◽

Short Communication ◽

Treatment Choice ◽

Clinical Indication ◽

Potential Treatment ◽

Polyphenolic Compound ◽

Viral Protease ◽

Respiratory Condition ◽

The World ◽

Innovative Work

Covid sickness 2019 (COVID‐19) flare-up is a continuous pandemic brought about by serious intense respiratory condition Covid 2 (SARS‐CoV‐2) with impressive mortality around the world. The fundamental clinical indication of COVID‐19 is the presence of respiratory side effects; however a few patients create extreme cardiovascular and renal inconveniences. There is desperation to comprehend the instrument by which this infection causes difficulties to create treatment choices. Curcumin, a characteristic polyphenolic compound, could be a potential treatment choice for patients with Covid infection. In this examination, we audit a portion of the likely impacts of curcumin, for example, repressing the section of infection to the phone, restraining epitome of the infection and viral protease, just as tweaking different cell flagging pathways. This survey gives a premise to additional innovative work of clinical utilizations of curcumin for the treatment of recently arose SARS‐CoV‐2.

Download Full-text

Medicinal Marijuana: A Promising Potential Treatment for Obstructive Sleep Apnea

University of Ottawa Science Undergraduate Research Journal ◽

10.18192/osurj.v2i1.4173 ◽

2019 ◽

Vol 2 (1) ◽

Author(s):

Gurvir Rai ◽

Anokhee Thakker ◽

Hasti Patel

Keyword(s):

Cardiovascular Disease ◽

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Side Effects ◽

Medical Devices ◽

Upper Airway ◽

Potential Treatment ◽

Efficacy And Safety ◽

Obstructive Sleep

Obstructive Sleep Apnea (OSA) is a common sleep disorder in mammals which is characterized by the repeated collapse of the upper airway. It is a known cause of hypertension, cardiovascular disease, and, in some cases, death. OSA is commonly treated by medical devices and surgeries. Although effective, these treatments are associated with unwanted side-effects and further complications. In recent years, the role of medicinal marijuana has grown as a potential treatment for sleep disorders. Further research must be conducted to determine the efficacy and safety of cannabis as a treatment for OSA.

Download Full-text

Radiotherapy side effects: integrating survivorship clinical lens to better serve patients

Current Oncology ◽

10.3747/co.27.6233 ◽

2019 ◽

Vol 27 (2) ◽

Author(s):

Vanessa Di Lalla ◽

G. Chaput ◽

Tristan Williams ◽

Khalil Sultanem

Keyword(s):

Side Effects ◽

Advanced Disease ◽

Early Stage ◽

Locally Advanced ◽

Primary Care Providers ◽

Care Providers ◽

Cancer Society ◽

Locally Advanced Tumors ◽

After Cancer ◽

Anxiety Depression

The Canadian Cancer Society estimated 220,400 new cases of cancer would be diagnosed in 2019. Of these, over 60% will survive for 5 years or more after cancer diagnosis1. Furthermore, nearly 40% of cancer patients receive at least one course of radiotherapy (RT)2. RT is utilized for both curative and palliative intents, to treat early stage or locally advanced tumors and for symptom management in advanced disease, respectively. RT can be delivered systemically, referred to as external-beam RT, or internally via brachytherapy3. Although technique improvements have drastically reduced RT-related toxicity3, most patients still experience burdensome RT side effects (SE)4. RT SE are local or loco-regional, and manifest in tissues or organs that were radiated. SE manifesting during within weeks following RT completion are defined as early SE, whereas those occurring after months or years are defined as late SE4. In addition to radiation oncologists, general practitioners in oncology and primary care providers are involved in survivorship care and management of RT SE5. This article presents an overview of common SE and respective management: anxiety, depression, fatigue, and SE related to these treatment sites: head and neck, thoracic, and pelvic.

Download Full-text