scholarly journals Application of hypnosis in psychOncology: A review of the literature

2021 ◽  
Vol 39 (2) ◽  
pp. 263-275
Author(s):  
Sónia Remondes-Costa ◽  
Filipa Magalhães ◽  
Inês Martins ◽  
André Louro ◽  
Martim Santos ◽  
...  
Keyword(s):  
Side Effects ◽  
Cancer Patients ◽  
Web Of Science ◽  
Controlled Trials ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Cancer Disease ◽  
Pain Anxiety ◽  
Randomized Controlled ◽  
Anxiety Depression

Hypnosis is useful for multiple somatic and psychological disorders, particularly cancer disease-related issues. In fact, the literature points out that hypnosis is effective in helping patients deal with aspects disease related, as well as in reducing the side effects of treatment. This review of the literature aims to summarize and assess the evidence of the usefulness of hypnosis in cancer patients and was conducted based on articles published between 2012 and 2019. The databases used were: B-on, SciELO, MEDLINE, and Web of Science. Randomized controlled trials and non-randomized studies were assessed. Among 837 studies identified, nine met the inclusion criteria and were selected. The studies were consensual to the effectiveness of hypnosis in reducing a set of symptoms in cancer patients, mainly pain, anxiety, depression, fatigue, and insomnia. However, several methodological limitations were identified. The practice of hypnosis is related to a significant number of techniques and approaches that differ from each other, thus compromising the interpretation and generalization of its effects. This review updates the evidence and suggests that the study of the efficacy of hypnosis in cancer patients is still limited. Further research into the effectiveness and acceptability of hypnosis for cancer patients is recommended.

Febuxostat use and risks of CVD events, death from cardiac-cause and all-cause mortality: metaanalysis of randomized controlled trials

2020 ◽  
pp. jrheum.200307
Author(s):  
Hao Deng ◽  
Bao Long Zhang ◽  
Jin Dong Tong ◽  
Xiu Hong Yang ◽  
Hui Min Jin
Keyword(s):  
Web Of Science ◽  
Meta Analysis ◽  
Relevant Literature ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
Central Register ◽  
Increased Risk ◽  
All Cause Mortality

Objective To assess whether febuxostat use increases the risk of developing cardiovascular events, death from cardiac-cause and all-cause mortalities. Methods The relevant literature was searched in several databases including the MEDLINE (PubMed, 1 Jan. 1966–29 Feb. 2020), Web of science, EMBASE (1 Jan. 1974–29 Feb. 2020), ClinicalTrials.gov and Cochrane Central Register for Controlled Trials. Manual searches for references cited in the original studies and relevant review articles were also performed. All studies included in this metanalysis were published in English. Results In the end, 20 studies that met our inclusion criteria were included in this meta-analysis. Use of febuxostat was found not to be associated with an increased risk of all-cause mortality (RR = 0.87, 95% CI 0.57–1.32, P =0.507). Also, there was no association between febuxostat use and mortalities arising from cardiovascular diseases (CVD) (RR = 0.84, 95% CI 0.49–1.45, P=0.528). The RR also revealed that febuxostat use was not associated with CVD events (RR = 0.98, 95% CI 0.83–1.16, P =0.827). Furthermore, the likelihood of occurrence of CVD events was found not to be dependent on febuxostat dose (RR = 1.04, 95% CI 0.84–1.30, P =0.723). Conclusion Febuxostat use is not associated with increased risks of all-cause mortality, death from CVD or CVD events. Accordingly, it is a safe drug for the treatment of gout. Systematic review registration: PROSPERO CRD42019131872

Review of neurological side effects associated with checkpoint inhibitor therapy in cancer patients.

2020 ◽  
Vol 38 (5_suppl) ◽  
pp. 72-72
Author(s):  
Lakshmi Manogna Chintalacheruvu ◽  
Kushal Naha ◽  
Vamsi Krishna Chilluru ◽  
Donald C. Doll
Keyword(s):  
Side Effects ◽  
Confidence Interval ◽  
Randomized Controlled Trials ◽  
Cancer Patients ◽  
Checkpoint Inhibitors ◽  
Controlled Trials ◽  
Close Monitoring ◽  
Check Point ◽  
Randomized Controlled ◽  
Check Point Inhibitors

72 Background: Checkpoint inhibitors have demonstrated efficacy in many cancer types. Neurological side effects are not well studied with check point inhibitors therapy. We conducted systematic review and meta analysis to evaluate the incidence of neurological side effects among various check point inhibitors. Methods: Eligible studies were searched for in PubMed and Google scholar. We searched for randomized controlled trials with cancer patients treated with check point inhibitors with neurological adverse effects. A total of 26 randomized controlled trials involving 6110 patients met eligibility criteria for the study. Results: Incidence rate of all grade neurological side effects include 5.6%(95% confidence interval [CI], 5.4-6.7%). Most common side effects include Headache (4.6%) (95% confidence interval [CI] 3.7-4.7%) followed by peripheral neuropathy (0.3%) (95% confidence interval [CI] 0.1-0.5%). Ipilimumab plus Nivolumab is associated with higher risk of headache and serious neurological side effects including myasthenia gravis, encephalitis, toxic encephalopathy and seizures. Conclusions: The incidence of neurological side effects associated with immune checkpoint inhibitors is low but not negligable. Patients on combination immunotherapy need more close monitoring for serious neurological side effects.

scholarly journals Virtual Reality-based Interventions for Patients with Paranoia

2020 ◽  
Author(s):  
Elham Monaghesh ◽  
Taha Samad-Soltani ◽  
Sara Farhang
Keyword(s):  
Virtual Reality ◽  
Web Of Science ◽  
Controlled Trials ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
Main Target ◽  
Paranoid Symptoms ◽  
Review Reports ◽  
The Cost ◽  
Positive Results

Abstract Background: Paranoia is an important psychiatric symptom with an important effect on daily life. Virtual reality (VR) based treatments are suggested as an effectual treatment for patients with paranoia, facilitating learning. To our knowledge, there is a lack of systematic reviews to evaluate VR-based treatment as a treatment for paranoia or paranoid delusions. This study aimed to review reports that investigate VR-based treatment as a treatment for patients with paranoia.Methods: Studies published up to 20/07/2020 about VR-based interventions for the treatment of patients with paranoid delusions or paranoia were reviewed in five databases including PubMed, Embase, Web of Science, PsycINFO, and Scopus.Results: From the total of 252 initial searches, 6 were included in the study based on inclusion criteria. Four studies were performed as randomized controlled trials and two were before-after studies. All of them showed positive results in the main target, including increased social participation, reduced anxiety, and suspicious ideas and paranoid symptoms. Conclusion: VR-based interventions are effective treatments. Although the use of VR technology is limited for a variety of reasons, including the cost, it improves symptoms in patients with paranoia.

scholarly journals Systematic review of randomized controlled trials of therapeutic hypothermia as a neuroprotectant in post cardiac arrest patients

CJEM ◽  
2006 ◽  
Vol 8 (05) ◽  
pp. 329-337 ◽  
Author(s):  
Ka Wai Cheung ◽  
Robert S. Green ◽  
Kirk D. Magee
Keyword(s):  
Systematic Review ◽  
Cardiac Arrest ◽  
Side Effects ◽  
Randomized Controlled Trials ◽  
Mild Hypothermia ◽  
Neurologic Outcome ◽  
Controlled Trials ◽  
Induced Hypothermia ◽  
Inclusion Criteria ◽  
Randomized Controlled

ABSTRACTObjective:Several randomized controlled trials have suggested that mild induced hypothermia may improve neurologic outcome in comatose cardiac arrest survivors. This systematic review of randomized controlled trials was designed to determine if mild induced hypothermia improves neurologic outcome, decreases mortality, or is associated with an increased incidence of adverse events.Data sources:The following databases were reviewed: Cochrane Controlled Trials Register (Issue 4, 2005), MEDLINE (January 1966 to November 2005), EMBASE (1980 to November 2005), CINAHL (1982 to November 2005) and Web of Science (1989 to November 2005). For each included study, references were reviewed and the primary author contacted to identify any additional studies.Study selection:Studies that met inclusion criteria were randomized controlled trials of adult patients (>18 years of age) with primary cardiac arrest who remained comatose after return of spontaneous circulation. Patients had to be randomized to mild induced hypothermia (32°C-34°C) or normothermia within 24 hours of presentation. Only studies reporting pre-determined outcomes including discharge neurologic outcome, mortality or significant treatment-related adverse events were included. There were no language or publication restrictions.Data synthesis:Four studies involving 436 patients, with 232 cooled to a core temperature of 32°C-34°C met inclusion criteria. Pooled data demonstrated that mild hypothermia decreased inhospital mortality (relative ratio [RR] 0.75; 95% confidence interval [CI], 0.62-0.92) and reduced the incidence of poor neurologic outcome (RR 0.74; 95% CI, 0.62-0.84). Numbers needed to treat were 7 patients to save 1 life, and 5 patients to improve neurologic outcome. There was no evidence of treatment-limiting side effects.Conclusions:Therapeutically induced mild hypothermia decreases in-hospital mortality and improves neurologic outcome in comatose cardiac arrest survivors. The possibility of treatment-limiting side effects cannot be excluded.

Efficacy of the detection of the early symptoms of Cancer cell, Prevention and the diagnosis procedure

2020 ◽  
Vol 16 ◽  
Author(s):  
Md Mahfujul Islam ◽  
Md Al Amin Molla
Keyword(s):  
Cancer Cells ◽  
Reference Lists ◽  
Web Of Science ◽  
Screening Program ◽  
Bibliographic Databases ◽  
Controlled Trials ◽  
Conference Paper ◽  
Cancer Awareness ◽  
Short Term ◽  
Randomized Controlled

: The aim to examine the signs for the potency of interventions to raise cancer awareness along with promote early demonstration in most cancers to share with future and policy investigation. Several peer-reviewed journals as well as books, conference paper and authentic website (like as NCBI, PubMed, CRI, CRU, Google Scholar, MEDLINE, Web of Science, etc.) Also, we looked for bibliographic databases and reference lists Such as randomized controlled trials of interventions brought to Individuals and commanded or uncontrolled reports of interventions brought to communities. The results found the signs that interventions reach to people subconsciously increase the cancer awareness from the short term and inadequate signs they advertise premature demonstration. This analysis helps to find appropriate info about categorizing the early indicators of many kinds of cancer cells on addition to appropriate guidelines to conquer cancer in low-Mid center income areas. Whereas contained the structured screening program, which helps detect cancer early and having a heightened chance of therapeutic and treatment content, taking essential measures to elevate the consciousness of the detectable symptoms.

scholarly journals The global summit on the efficacy and effectiveness of spinal manipulative therapy for the prevention and treatment of non-musculoskeletal disorders: a systematic review of the literature

2021 ◽  
Vol 29 (1) ◽  
Author(s):  
Pierre Côté ◽  
Jan Hartvigsen ◽  
Iben Axén ◽  
Charlotte Leboeuf-Yde ◽  
Melissa Corso ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Musculoskeletal Disorders ◽  
Methodological Quality ◽  
Spinal Manipulative Therapy ◽  
Controlled Trials ◽  
Primary Dysmenorrhea ◽  
Review Of The Literature ◽  
Manipulative Therapy ◽  
Randomized Controlled

Abstract Background A small proportion of chiropractors, osteopaths, and other manual medicine providers use spinal manipulative therapy (SMT) to manage non-musculoskeletal disorders. However, the efficacy and effectiveness of these interventions to prevent or treat non-musculoskeletal disorders remain controversial. Objectives We convened a Global Summit of international scientists to conduct a systematic review of the literature to determine the efficacy and effectiveness of SMT for the primary, secondary and tertiary prevention of non-musculoskeletal disorders. Global summit The Global Summit took place on September 14–15, 2019 in Toronto, Canada. It was attended by 50 researchers from 8 countries and 28 observers from 18 chiropractic organizations. At the summit, participants critically appraised the literature and synthesized the evidence. Systematic review of the literature We searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, the Cumulative Index to Nursing and Allied Health, and the Index to Chiropractic Literature from inception to May 15, 2019 using subject headings specific to each database and free text words relevant to manipulation/manual therapy, effectiveness, prevention, treatment, and non-musculoskeletal disorders. Eligible for review were randomized controlled trials published in English. The methodological quality of eligible studies was assessed independently by reviewers using the Scottish Intercollegiate Guidelines Network (SIGN) criteria for randomized controlled trials. We synthesized the evidence from articles with high or acceptable methodological quality according to the Synthesis without Meta-Analysis (SWiM) Guideline. The final risk of bias and evidence tables were reviewed by researchers who attended the Global Summit and 75% (38/50) had to approve the content to reach consensus. Results We retrieved 4997 citations, removed 1123 duplicates and screened 3874 citations. Of those, the eligibility of 32 articles was evaluated at the Global Summit and 16 articles were included in our systematic review. Our synthesis included six randomized controlled trials with acceptable or high methodological quality (reported in seven articles). These trials investigated the efficacy or effectiveness of SMT for the management of infantile colic, childhood asthma, hypertension, primary dysmenorrhea, and migraine. None of the trials evaluated the effectiveness of SMT in preventing the occurrence of non-musculoskeletal disorders. Consensus was reached on the content of all risk of bias and evidence tables. All randomized controlled trials with high or acceptable quality found that SMT was not superior to sham interventions for the treatment of these non-musculoskeletal disorders. Six of 50 participants (12%) in the Global Summit did not approve the final report. Conclusion Our systematic review included six randomized clinical trials (534 participants) of acceptable or high quality investigating the efficacy or effectiveness of SMT for the treatment of non-musculoskeletal disorders. We found no evidence of an effect of SMT for the management of non-musculoskeletal disorders including infantile colic, childhood asthma, hypertension, primary dysmenorrhea, and migraine. This finding challenges the validity of the theory that treating spinal dysfunctions with SMT has a physiological effect on organs and their function. Governments, payers, regulators, educators, and clinicians should consider this evidence when developing policies about the use and reimbursement of SMT for non-musculoskeletal disorders.

scholarly journals Manual Therapy in Cervical and Lumbar Radiculopathy: A Systematic Review of the Literature

2021 ◽  
Vol 18 (11) ◽  
pp. 6176
Author(s):  
Tomasz Kuligowski ◽  
Anna Skrzek ◽  
Błażej Cieślik
Keyword(s):  
Manual Therapy ◽  
Functional Outcomes ◽  
Web Of Science ◽  
Current Knowledge ◽  
Controlled Trial ◽  
Future Research ◽  
Lumbar Radiculopathy ◽  
Inclusion Criteria ◽  
Randomized Controlled ◽  
The Mean

The aim of this study was to describe and update current knowledge of manual therapy accuracy in treating cervical and lumbar radiculopathy, to identify the limitations in current studies, and to suggest areas for future research. The study was conducted according to PRISMA guidelines for systematic reviews. A comprehensive literature review was conducted using PubMed and Web of Science databases up to April 2020. The following inclusion criteria were used: (1) presence of radiculopathy; (2) treatment defined as manual therapy (i.e., traction, manipulation, mobilization); and (3) publication defined as a Randomized Controlled Trial. The electronic literature search resulted in 473 potentially relevant articles. Finally, 27 articles were accepted: 21 on cervical (CR) and 6 in lumbar radiculopathy (LR). The mean PEDro score for CR was 6.6 (SD 1.3), and for LR 6.7 (SD 1.6). Traction-oriented techniques are the most frequently chosen treatment form for CR and are efficient in reducing pain and improving functional outcomes. In LR, each of the included publications used a different form of manual therapy, which makes it challenging to summarize knowledge in this group. Of included publications, 93% were either of moderate or low quality, which indicates that quality improvement is necessary for this type of research.

scholarly journals Netiquette: Ethic, Education, and Behavior on Internet—A Systematic Literature Review

2021 ◽  
Vol 18 (3) ◽  
pp. 1212
Author(s):  
Rebeca Soler-Costa ◽  
Pablo Lafarga-Ostáriz ◽  
Marta Mauri-Medrano ◽  
Antonio-José Moreno-Guerrero
Keyword(s):  
Information And Communication Technologies ◽  
Web Of Science ◽  
Communication Technologies ◽  
Measurement Methods ◽  
Cyber Bullying ◽  
Fake News ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Information And Communication ◽  
And Behavior

In this article, an analysis of the existing literature is carried out. It focused on the netiquette (country, date, objectives, methodological design, main variables, sample details, and measurement methods) included in the Web of Science and Scopus databases. This systematic review of the literature has been developed entirely according to the Preferred Reporting Items for Systematic Reviews (PRISMA). The initial search yielded 53 results, of which 18 exceeded the inclusion criteria and were analyzed in detail. These results show that this is a poorly defined line of research, both in theory and in practice. There is a need to update the theoretical framework and an analysis of the empirical proposals, whose samples are supported by students or similar. Knowing, understanding, and analyzing netiquette is a necessity in a society in which information and communication technologies (ICT) have changed the way of socializing and communicating. A new reality in which there is cyber-bullying, digital scams, fake news, and haters on social networks.

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