scholarly journals SOLRIAMFETOL TITRATION AND ADMINISTRATION: PHYSICIAN TITRATION STRATEGIES IN A HYPOTHETICAL PATIENT WITH OSA

CHEST Journal ◽  
2021 ◽  
Vol 160 (4) ◽  
pp. A2410-A2411
Author(s):  
Haramandeep Singh ◽  
Danielle Hyman ◽  
Gregory Parks ◽  
Abby Chen ◽  
Elizabeth Baldys ◽  
...  
Keyword(s):  
2021 ◽  
Vol 31 (2) ◽  
pp. 238-249
Author(s):  
E. G. Furman ◽  
V. V. Shadrina ◽  
T. Yu. Maksimycheva ◽  
V. D. Sherman ◽  
E. I. Kondratyeva

Despite the low prevalence of cystic fibrosis (CF), the costs of treating this disease are significant for the healthcare system. The aim of this economic study was to assess the total cost of drugs per year for children with CF, depending on age and course of the disease.Methods. For this pharmacoeconomic analysis, groups of “hypothetical” patients were formed according to the characteristics of the course of CF, taking into account the required volume of basic CF therapy, antibiotic therapy, and complications.Results. The cost of basic treatment for CF patients of different ages and disease progression in the hypothetical patient models can vary greatly. The cost of CF therapy increases significantly with age and Pseudomonas aeruginosa respiratory infection, especially in the patients with chronic infection, concomitant polyposis sinusitis, and low nutritional status.Conclusion. Patients with CF require regular follow-up with control of the microflora of the respiratory tract and effective eradication therapy for P. aeruginosa and other pathogenic microorganisms. Reducing infection rates and the severity of the disease can lead to significant cost savings.


2015 ◽  
Vol 8 (4) ◽  
pp. 32 ◽  
Author(s):  
Solmaz Araghi ◽  
Rohollah Sharifi ◽  
Goran Ahmadi ◽  
Mahsa Esfehani ◽  
Fatemeh Rezaei

<p><strong>INTRODUCTION</strong><strong>:</strong> In dentistry, medicine often prescribed to relieve pain and remove infections .Therefore, wrong prescription can lead to a range of problems including lack of pain, antimicrobial treatment failure and the development of resistance to antibiotics.</p> <p><strong>MATERIALS &amp; METHODS</strong><strong>:</strong> In this cross-sectional study, the aim was to evaluate the common errors in written prescriptions by general dentists in Kermanshah in 2014. Dentists received a questionnaire describing five hypothetical patient and the appropriate prescription for the patient in question was asked. Information about age, gender, work experience and the admission in university was collected. The frequency of errors in prescriptions was determined. Data by SPSS 20statistical software and using statistical t-test, chi-square and Pearson correlation were analyzed (0.05&gt; P).</p> <p><strong>RESULTS</strong><strong>: </strong>A total of 180 dentists (62.6% male and 37.4% female) with a mean age of 8.23 ± 39.199 participated in this study. Prescription errors include the wrong in pharmaceutical form (11%), not having to write therapeutic dose (13%), writing wrong dose (14%), typos (15%), error prescription (23%) and writing wrong number of drugs (24%).The most frequent errors in the administration of antiviral drugs (31%) and later stages of antifungal drugs (30%), analgesics (23%) and antibiotics (16%) was observed. Males dentists compared with females dentists showed more frequent errors (P=0.046). Error frequency among dentists with a long work history (P&gt;0.001) and the acceptance in the university except for the entrance examination (P=0.041) had a statistically significant relationship.</p> <p><strong>CONCLUSION</strong><strong>:</strong> This study showed that the written prescription by general dentists examined contained significant errors and improve prescribing through continuing education of dentists is essential.</p>


2020 ◽  
Vol 6 (4) ◽  
pp. 00342-2020
Author(s):  
Hamid Akbarshahi ◽  
Zainab Ahmadi ◽  
David C. Currow ◽  
Jacob Sandberg ◽  
Zac Vandersman ◽  
...  

IntroductionCOPD is a major cause of morbidity and mortality. The prevalence, morbidity and mortality of COPD among females have increased. Previous studies indicate a possible gender bias in the diagnosis and management of COPD. The present study aims to determine if there is gender bias in the management of COPD in Sweden.MethodsThis was a double-blind, randomised (1:1), controlled, parallel-group, web-based trial using the hypothetical case scenario of a former smoker (40 pack-years and quit smoking 3 years ago) who was male or female. The participants were blind to the randomisation and the purpose of the trial. The case progressively revealed more information with associated questions on how the physician would manage the patient. Study participants chose from a list of tests and treatments at each step of the case scenario.ResultsIn total, 134 physicians were randomised to a male (n=62) or a female (n=72) case. There was no difference in initial diagnosis (61 (98%) male cases and 70 (97%) female cases diagnosed with COPD) and planned diagnostic procedures between the male and female cases. Spirometry was chosen by all the physicians as one of the requested diagnostic tests. The management of the hypothetical COPD case did not differ by sex of the responding physician.ConclusionIn Sweden, diagnosis and management of a hypothetical patient with COPD did not differ by the gender of the patient or physician.


2021 ◽  
Author(s):  
Jeong Min Kim ◽  
Hwa Kyung Lim ◽  
Jae-Hyeon Ahn ◽  
Kyoung Hwa Lee ◽  
Kwang Suk Lee ◽  
...  

BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic has caused an unprecedented burden on healthcare systems. OBJECTIVE To effectively triage COVID-19 patients within situations of limited data availability and to explore optimal thresholds to minimize mortality rates while maintaining the healthcare system capacity. METHODS A nationwide sample of 5601 patients confirmed for COVID-19 up until April 2020 was retrospectively reviewed. XGBoost and logistic regression analysis were used to develop prediction models for the patients’ maximum clinical severity during hospitalization, classified according to the WHO Ordinal Scale for Clinical Improvement (OSCI). The recursive feature elimination technique was used to evaluate the extent of the model performance’s maintenance when clinical and laboratory variables are eliminated. Using populations based on hypothetical patient influx scenarios, discrete-event simulation was performed to find the optimal threshold within limited resource environments that minimizes mortality rates. RESULTS The cross-validated area under the receiver operating characteristics (AUROC) of the baseline XGBoost model that utilized all 37 variables was 0.965 for OSCI ≥ 6. Compared to the baseline model’s performance, the AUROC of the feature-eliminated model that utilized 17 variables was maintained at 0.963 with statistical insignificance. Our prediction model was provided online for clinical implementation. Optimal thresholds were found to minimize mortality rates in a hypothetical patient influx scenario. The benefit of utilizing an optimal triage threshold was clear, reducing mortality up to 18.1% compared to the conventional Youden Index. CONCLUSIONS Our adaptive triage model and its threshold optimization capability reveal that COVID-19 management can be integrated using both medical and healthcare management sectors to guarantee maximum treatment efficacy.


Author(s):  
Justine Seymour ◽  
Jennifer L. Barnes ◽  
Julie Schumacher ◽  
Rachel L. Vollmer

The purpose of this study was to determine whether weight bias exhibited by health care professionals (HCPs) impacts quality of health care provided to individuals with obesity. HCPs (n = 220; 88% female, 87% nurses) in the Midwest region of the United States were recruited to complete an online survey. In this within-subjects study design, participants completed the Attitudes Towards Obese Persons (ATOP) scale to assess weight bias and responded to 2 (1 person with obesity and 1 person without obesity) hypothetical patient scenarios to evaluate quality of care. A median split was calculated for ATOP scores to divide participants into high or low weight bias groups. Within these groups, thematic analysis was used to uncover themes in quality of care based on participants’ responses to each scenario. The analysis revealed that HCPs in the high weight bias group gave specific diet and exercise recommendations, offered health advice regarding weight loss, and used less teaching discourse when responding to the patient with obesity. In addition, in both weight bias groups, patients with obesity were started on pharmaceutical therapies sooner. The findings of this study suggest a need to educate HCPs on the importance of empathy and compassion when providing treatment to all patients, regardless of weight, to increase quality of care and ultimately improve patient outcomes.


2016 ◽  
Vol 9 (4) ◽  
pp. 611-615 ◽  
Author(s):  
Ankita Tandon ◽  
Ming Wang ◽  
Kevin C. Roe ◽  
Surju Patel ◽  
Nasrollah Ghahramani

2009 ◽  
Vol 13 (6) ◽  
pp. 303-307 ◽  
Author(s):  
Dalia Mikhael ◽  
Kelly Babcock ◽  
Jean-Pierre DesGroseilliers

Background: Knowledge of the cost of various psoriasis therapeutic options is essential to the prescribing clinician. Objective: To compare the cost of various psoriasis treatments over a 10-year period in the province of Ontario, Canada. Methods: We used a hypothetical patient with plaque-type psoriasis of moderate severity with a Psoriasis Area and Severity Index of 10, body surface area of 20%, and no joint involvement. The costs to treat this hypothetical patient with different therapeutic regimens were compared in this study. Results: In a 60 kg patient, alefacept was the most costly form of therapy, based on two 12-week treatments per year, followed by infliximab 5 mg/kg. In a 90 kg patient, infliximab 5 mg/kg was the most costly, followed by alefacept. The least costly treatment was ultraviolet B phototherapy. Conclusion: With the knowledge of these data, informed prescribing by the dermatologist may reduce the financial burden to the patient, the provincial health care system, and insurance companies.


1985 ◽  
Vol 56 (1) ◽  
pp. 171-175
Author(s):  
James W. Croake

The Psychological Testing Report Form is presented as an alternative to the psychologist's usual narrative report. Legal and ethical considerations make the reporting of each patient's psychological testing important. Efficient use of psychologist's time and greater utility among disciplines within psychiatric settings points to the possible value of a more formally standardized test-reporting form. An hypothetical patient and her test scores are used to illustrate the simplicity and usefulness of the form.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Ronald S. Gibbs ◽  
Carolyn Wieber ◽  
Leslie Myers ◽  
Timothy Jenkins

Because inappropriate use of antibiotics is common, it is an important area for continuing medical education. At an annual review, we conducted a two-year campaign to achieve appropriate use. Our methods included two surveys, directed course content, programmatic evaluation, and a sample practice audit. Ninety percent of learners perceived inappropriate antibiotic use as a “very big” or “big” problem in the United States, but only 44% perceived this about their practice (P<0.001). Top perceived barriers to appropriate antibiotic use were patient expectations, breaking old habits, and fear that patients would go elsewhere. Top strategies to overcome these barriers were patient educational materials, having guidelines accessible, and developing practice policies. In a hypothetical patient with acute bronchitis, 98% would likely prescribe an antibiotic in certain clinical scenarios even though The Centers for Disease Control and Prevention does not recommend empiric antibiotic treatment. The most common scenarios leading to likely antibiotic prescription were symptoms over 15 days (84%), age over 80 years (70%), and fever (48%). Practitioners are under multiple pressures to prescribe antibiotics even in situations where antibiotics are not recommended (such as acute bronchitis). To achieve complex practice changes such as avoiding inappropriate antibiotic use, no one strategy predominated.


2021 ◽  
pp. 026921632110483
Author(s):  
Nicola White ◽  
Linda JM Oostendorp ◽  
Victoria Vickerstaff ◽  
Christina Gerlach ◽  
Yvonne Engels ◽  
...  

Background: The Surprise Question (‘Would I be surprised if this patient died within 12 months?’) identifies patients in the last year of life. It is unclear if ‘surprised’ means the same for each clinician, and whether their responses are internally consistent. Aim: To determine the consistency with which the Surprise Question is used. Design: A cross-sectional online study of participants located in Belgium, Germany, Italy, The Netherlands, Switzerland and UK. Participants completed 20 hypothetical patient summaries (‘vignettes’). Primary outcome measure: continuous estimate of probability of death within 12 months (0% [certain survival]–100% [certain death]). A threshold (probability estimate above which Surprise Question responses were consistently ‘no’) and an inconsistency range (range of probability estimates where respondents vacillated between responses) were calculated. Univariable and multivariable linear regression explored differences in consistency. Trial registration: NCT03697213. Setting/participants: Registered General Practitioners (GPs). Of the 307 GPs who started the study, 250 completed 15 or more vignettes. Results: Participants had a consistency threshold of 49.8% (SD 22.7) and inconsistency range of 17% (SD 22.4). Italy had a significantly higher threshold than other countries ( p = 0.002). There was also a difference in threshold levels depending on age of clinician, for every yearly increase, participants had a higher threshold. There was no difference in inconsistency between countries ( p = 0.53). Conclusions: There is variation between clinicians regarding the use of the Surprise Question. Over half of GPs were not internally consistent in their responses to the Surprise Question. Future research with standardised terms and real patients is warranted.


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