Muscle mass does not automatically equal muscle strength – results from a retrospective analysis of a multimodal intervention for cancer patients

2021 ◽  
Vol 46 ◽  
pp. S606-S607
Author(s):  
L. Gafner ◽  
M. Schläppi ◽  
M. Wyss ◽  
V. Fretz ◽  
M. Rühlin ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Retrospective Analysis ◽  
Cancer Patients ◽  
Muscle Mass ◽  
Multimodal Intervention

scholarly journals The Impact of Protein Supplementation Targeted at Improving Muscle Mass on Strength in Cancer Patients: A Scoping Review

Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 2099 ◽  
Author(s):  
Michela Zanetti ◽  
Gianluca Gortan Cappellari ◽  
Rocco Barazzoni ◽  
Gianfranco Sanson
Keyword(s):  
Amino Acid ◽  
Muscle Strength ◽  
Cancer Patients ◽  
Muscle Mass ◽  
Scoping Review ◽  
Functional Limitation ◽  
Protein Supplementation ◽  
Energy Deficit ◽  
Amino Acid Supplementation ◽  
The Impact

Deterioration of muscle strength during cancer results in functional limitation, poor quality of life and reduced survival. The indirect effects on muscle strength of nutritional interventions based on protein and amino acid derivatives targeted at improving muscle mass are poorly documented. A scoping review was performed to examine the available evidence on the effects of proteins, amino acids and their derivatives on muscle strength in adult cancer patients. Pubmed and Scopus databases were searched to identify research articles published in the last 10 years. Fourteen studies met the inclusion criteria, showing that changes in muscle strength following protein or amino acid supplementation are generally concordant with those in muscle mass in cancer patients. Administration of both energy and proteins in the presence of reduced oral intakes results in more robust effects on both muscle strength and mass. It is not clear whether this is due to the correction of the energy deficit or to an interaction between proteins and other macronutrients. The optimal mixture, type, and dose of amino acid/protein supplementation alone or in combination with other anabolic strategies should be determined to provide the best nutritional approach in cancer.

scholarly journals Correlation Between Omega-3 Fatty Acids Plasma Levels with Muscle Mass and Handgrip-Muscle Strength in Head Neck Cancer Patients Undergoing Radiotherapy in Ciptomangunkusumo Hospital Jakarta

2019 ◽  
Vol 3 (1) ◽  
pp. 32
Author(s):  
Elfina Rachmi ◽  
Inge Permadhi ◽  
Angela Giselvania
Keyword(s):  
Fatty Acids ◽  
Muscle Strength ◽  
Cancer Patients ◽  
Muscle Mass ◽  
Neck Cancer ◽  
Head Neck Cancer ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Cross Sectional ◽  
Head Neck

Background. Cancer cachexia is common in head neck cancer caused by increasing proinflammatory cytokines, has effect on hipermetabolism, increased nutritional needs, anorexia, decreased muscle mass and body weight. Omega-3 fatty acids play a role in reducing inflammation, improving muscle mass and handgrip.Objective. This cross sectional study conducted in Department of Radiotherapy Dr. CiptoMangunkusumo Hospital, aimed to investigate correlation between omega-3 fatty acids plasma with muscle mass and hand grip-muscle strength in head neck cancer subjects undergoing radiotherapy.Method. This study was conducted from June to August 2016. The subjects were head neck cancer patients in stage I‒IV (18–65 years old) and had received >25 times radiation, and  obtained by consecutive sampling method. Total omega-3 fatty acids intake was obtained by semiquantitative Food Frequency Questionnaire. Anthropometric measurements used ShorrBoard and Smic® ZT-120, muscle mass used Omron HBF375®, and handgrip used Jamar® dinamometer. Omega-3 fatty acids plasma were examined by gas chromatography flame ionized detector. Correlation omega-3 fatty acids plasma with muscle mass were analyzed by Pearson, and correlation with handgrip by Spearman.Results. There were 52 subjects completed all examinations, received radiotherapy ≥25 times combination chemotherapy, 57% male, 50 years old. Most sites at nasopharynx, mostly stage IV, 25% subjects had normal body mass indeks, 75% were low. Most subjects had nutritional problems caused by inadequate intake of energy, protein, fat, and omega-3 fatty acids. Majority (75%) had small muscle mass (28.4±4.7%), mostly (75%) normal handgrip, median 37.1(25.7‒68.5) kg, and all subjects had very low omega-3 fatty acids plasma (2.5±0.8%). There was strong correlation between omega-3 fatty acids plasma with muscle mass (r =0.6, p <0.05) and handgrip (r =0.8, p <0.001) who received radiotherapy  (>60–70 Gy), no correlation less than that doses.Conclusion. There was correlation between omega-3 fatty acids plasma with muscle mass and handgrip, at radiotherapy doses >60–70 Gy.

scholarly journals Augmentation Index Is Inversely Associated with Skeletal Muscle Mass, Muscle Strength, and Anaerobic Power in Young Male Adults: A Preliminary Study

2021 ◽  
Vol 11 (7) ◽  
pp. 3146
Author(s):  
Dongmin Lee ◽  
Kyengho Byun ◽  
Moon-Hyon Hwang ◽  
Sewon Lee
Keyword(s):  
Skeletal Muscle ◽  
Muscle Strength ◽  
Arterial Stiffness ◽  
Muscle Mass ◽  
Muscular Strength ◽  
Skeletal Muscle Mass ◽  
Augmentation Index ◽  
Anaerobic Power ◽  
Negatively Associated ◽  
Increased Risk

Arterial stiffness is associated with an increased risk of cardiovascular disease. Previous studies have shown that there is a negative correlation between arterial stiffness and variables such as skeletal muscle mass, muscular strength, and anaerobic power in older individuals. However, little research has been undertaken on relationships in healthy young adults. This study presents a preliminary research that investigates the association between arterial stiffness and muscular factors in healthy male college students. Twenty-three healthy young males (23.9 ± 0.5 years) participated in the study. The participants visited the laboratory, and variables including body composition, blood pressure, arterial stiffness, blood parameters, grip strength, and anaerobic power were measured. Measurements of augmentation index (AIx) and brachial-ankle pulse wave velocity (baPWV) were performed to determine arterial stiffness. There were significant positive correlations among skeletal muscle mass, muscle strength, and anaerobic power in healthy young adult males. AIx was negatively associated with a skeletal muscle mass (r = −0.785, p < 0.01), muscular strength (r = −0.500, p < 0.05), and anaerobic power (r = −0.469, p < 0.05), respectively. Likewise, AIx@75 corrected with a heart rate of 75 was negatively associated with skeletal muscle mass (r = −0.738, p < 0.01), muscular strength (r = −0.461, p < 0.05), and anaerobic power (r = −0.420, p < 0.05) respectively. However, the baPWV showed no correlation with all muscular factors. Our findings suggest that maintaining high levels of skeletal muscle mass, muscular strength, and anaerobic power from relatively young age may lower AIx.

scholarly journals P15-9 Factors correlated to muscle strength in breast cancer patients before chemotherapy

2021 ◽  
Vol 32 ◽  
pp. S337
Author(s):  
Devina A. Halim ◽  
Andree Kurniawan ◽  
Ratna D. Hatma ◽  
Asri Adisasmita ◽  
Sonar S. Panigoro ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Muscle Strength ◽  
Cancer Patients ◽  
Breast Cancer Patients

scholarly journals Respiratory Muscle Weakness as a Risk Factor for Pneumonia in Older People

Gerontology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Tatsuma Okazaki ◽  
Yoshimi Suzukamo ◽  
Midori Miyatake ◽  
Riyo Komatsu ◽  
Masahiro Yaekashiwa ◽  
...  
Keyword(s):  
Risk Factor ◽  
Muscle Strength ◽  
Older People ◽  
Serum Albumin ◽  
Muscle Mass ◽  
Muscle Weakness ◽  
Fat Mass ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Respiratory Muscle Weakness

Introduction: The respiratory muscle strength regulates the effectiveness of coughing, which clears the airways and protects people from pneumonia. Sarcopenia is an aging-related loss of muscle mass and function, the worsening of which is associated with malnutrition. The loss of respiratory and swallowing muscle strength occurs with aging, but its effect on pneumonia is unclear. This study aimed to determine the risks of respiratory muscle weakness on the onset and relapse of pneumonia in older people in conjunction with other muscle-related factors such as malnutrition. Methods: We conducted a longitudinal study with 47 pneumonia inpatients and 35 non-pneumonia controls aged 70 years and older. We evaluated the strength of respiratory and swallowing muscles, muscle mass, and malnutrition (assessed by serum albumin levels and somatic fat) during admission and confirmed pneumonia relapse within 6 months. The maximal inspiratory and expiratory pressures determined the respiratory muscle strength. Swallowing muscle strength was evaluated by tongue pressure. Bioelectrical impedance analysis was used to evaluate the muscle and fat mass. Results: The respiratory muscle strength, body trunk muscle mass, serum albumin level, somatic fat mass, and tongue pressure were significantly lower in pneumonia patients than in controls. Risk factors for the onset of pneumonia were low inspiratory respiratory muscle strength (odds ratio [OR], 6.85; 95% confidence interval [CI], 1.56–30.11), low body trunk muscle mass divided by height2 (OR, 6.86; 95% CI, 1.49–31.65), and low serum albumin level (OR, 5.46; 95% CI, 1.51–19.79). For the relapse of pneumonia, low somatic fat mass divided by height2 was a risk factor (OR, 20.10; 95% CI, 2.10–192.42). Discussion/Conclusions: Respiratory muscle weakness, lower body trunk muscle mass, and malnutrition were risk factors for the onset of pneumonia in older people. For the relapse of pneumonia, malnutrition was a risk factor.

Relationship between trunk muscle strength and trunk muscle mass and thickness using bioelectrical impedance analysis and ultrasound imaging

2021 ◽  
pp. 1-10
Author(s):  
Ryo Miyachi ◽  
Nana Koike ◽  
Suzu Kodama ◽  
Junya Miyazaki
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Ultrasound Imaging ◽  
Bioelectrical Impedance Analysis ◽  
Muscle Thickness ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Trunk Muscle ◽  
Trunk Muscles ◽  
Trunk Muscle Strength

BACKGROUND: Although trunk muscles are involved in many important functions, evaluating trunk muscle strength is not an easy task. If trunk muscle mass and thickness could be used as indicators of trunk muscle strength, the burden of measurement would be reduced, but the relationship between trunk muscle strength and trunk muscle mass and thickness has not been clarified. OBJECTIVE: The purpose of this study was to clarify the relationship between trunk muscle strength and trunk muscle mass by bioelectrical impedance analysis and trunk muscle thickness by ultrasound imaging in healthy adults. METHODS: One hundred and twenty-one healthy university students were included in this study. Trunk flexion/extension muscle strength and trunk muscle mass by bioelectrical impedance analysis, and trunk muscle thickness by ultrasound imaging were measured. RESULTS: Both trunk flexion strength and trunk extension strength were significantly correlated with trunk muscle mass and oblique and rectus abdominis muscle thickness. Multiple regression analysis showed that trunk extension muscle strength had an independent relationship with trunk muscle mass. CONCLUSIONS: This study demonstrated that trunk muscle mass or trunk muscle thickness can be used as an alternative means for evaluating trunk muscle strength, making the evaluation of trunk muscles less burdensome.

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