An adaptive drug delivery design using neural networks for effective treatment of infectious diseases: A simulation study

2009 ◽  
Vol 94 (3) ◽  
pp. 207-222 ◽  
Author(s):  
Radhakant Padhi ◽  
Jayender R. Bhardhwaj
2021 ◽  
Author(s):  
Junyong Zhang ◽  
Wencheng Liang ◽  
Lianlei Wen ◽  
Zhimin Lu ◽  
Yan Xiao ◽  
...  

Combining rapid microbial discrimination with antibacterial property, multi-functional biomacromolecules provide timely diagnoses and effective treatment on infectious diseases. Through a two-step approach of organocatalytic ring-opening copolymerization and thiol-ene modification, aggregation-induced...


Econometrics ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 17
Author(s):  
Konstantinos Gkillas ◽  
Christoforos Konstantatos ◽  
Costas Siriopoulos

We study the non-linear causal relation between uncertainty-due-to-infectious-diseases and stock–bond correlation. To this end, we use high-frequency 1-min data to compute daily realized measures of correlation and jumps, and then, we employ a nonlinear Granger causality test with the use of artificial neural networks so as to investigate the predictability of this type of uncertainty on realized stock–bond correlation and jumps. Our findings reveal that uncertainty-due-to-infectious-diseases has significant predictive value on the changes of the stock–bond relation.


Author(s):  
Abhinay Sharma ◽  
Pooja Sanduja ◽  
Aparna Anand ◽  
Pooja Mahajan ◽  
Carlos A. Guzman ◽  
...  

AbstractInfectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.


Author(s):  
Gustavo Hernandez-Mejia ◽  
Esteban A. Hernandez-Vargas ◽  
Alma Y. Alanis ◽  
Nancy Arana-Daniel

2013 ◽  
Vol 7 (1) ◽  
pp. 49-62 ◽  
Author(s):  
Vijaykumar Sutariya ◽  
Anastasia Groshev ◽  
Prabodh Sadana ◽  
Deepak Bhatia ◽  
Yashwant Pathak

Artificial neural networks (ANNs) technology models the pattern recognition capabilities of the neural networks of the brain. Similarly to a single neuron in the brain, artificial neuron unit receives inputs from many external sources, processes them, and makes decisions. Interestingly, ANN simulates the biological nervous system and draws on analogues of adaptive biological neurons. ANNs do not require rigidly structured experimental designs and can map functions using historical or incomplete data, which makes them a powerful tool for simulation of various non-linear systems.ANNs have many applications in various fields, including engineering, psychology, medicinal chemistry and pharmaceutical research. Because of their capacity for making predictions, pattern recognition, and modeling, ANNs have been very useful in many aspects of pharmaceutical research including modeling of the brain neural network, analytical data analysis, drug modeling, protein structure and function, dosage optimization and manufacturing, pharmacokinetics and pharmacodynamics modeling, and in vitro in vivo correlations. This review discusses the applications of ANNs in drug delivery and pharmacological research.


Entropy ◽  
2018 ◽  
Vol 20 (4) ◽  
pp. 249 ◽  
Author(s):  
Krzysztof Gajowniczek ◽  
Arkadiusz Orłowski ◽  
Tomasz Ząbkowski

2022 ◽  
Vol 429 ◽  
pp. 132409
Author(s):  
Li-Jyuan Luo ◽  
Duc Dung Nguyen ◽  
Chih-Ching Huang ◽  
Jui-Yang Lai

Sign in / Sign up

Export Citation Format

Share Document