The role of C-tactile nerve fibers in human social development

2022 ◽  
Vol 43 ◽  
pp. 20-26
Author(s):  
Ilona Croy ◽  
Merle T Fairhurst ◽  
Francis McGlone
Keyword(s):  
Social Development ◽  
Nerve Fibers

Philosophical and Pedagogical Views of Yu. F. Samarin

2019 ◽  
Vol 54 ◽  
pp. 209-218
Author(s):  
Lev E. Shaposhnikov
Keyword(s):  
National Identity ◽  
Social Development ◽  
Educational Policy ◽  
Critical Evaluation ◽  
Educational Process ◽  
Educational Context ◽  
The Government ◽  
Role Of Religion

The paper analyses the evolution of Yu. Samarin’s ideas from rationalism to “holistic knowledge”. Special attention is paid to the philosopher’s conceptualization of the key role of religion for a nation. The author also examines the scholar’s position concerning the promotion of patriotism as an important impetus for social development. Emphasis is made on analyzing the interaction of universal and national aspects in the educational process, as well as on the value of national identity in the field of humanities. The article also presents Yu. Samarin’s critical evaluation of the government educational policy and his suggestions on increasing its effectiveness. The author notes the relevance of Yu. Samarin’s views for the contemporary philosophical and educational context.

Social Development and Police Reform: Some Reflections on the Concept and Purpose of Policing and the Implications for Reform in the UK and USA

2020 ◽  
Author(s):  
Andrew Williams ◽  
Craig Paterson
Keyword(s):  
Social Development ◽  
Conceptual Understanding ◽  
Critical Question ◽  
Police Reform ◽  
Liberal Democratic ◽  
The Usa ◽  
Anglo American ◽  
The Uk ◽  
Common Understanding

Abstract The increase in calls for police reform following the death of George Floyd has led to renewed debate about social inequality and the role of policing in society. Modern bureaucratic police systems emerged from locally administered structures and Anglo-American policing models continue to be aligned, to varying degrees, with the political, socio-cultural, legal, and ideological aspects of contemporary liberal democratic society with its emphasis on democratic localism and decentralised accountability. However, at a time when society is reimagining itself and technology, government, and nations are radically re-shaping themselves, a critical question is whether there is a sufficiently common philosophical and conceptual understanding of policing to support its development rather than just a common understanding of police functions. This is profoundly important when considering the current calls for reform of policing in the USA and other western democratic states. The article argues that there is an urgent need to reconsider how we conceptualize policing and its relationship with social development.

Private Wealth, Philanthropy, and Social Development

2016 ◽  
Vol 8 (2) ◽  
pp. 215-248 ◽  
Author(s):  
Francis Barchi ◽  
Guosheng Deng ◽  
Chien-Chung Huang ◽  
Carolyn Isles ◽  
Juliann Vikse
Keyword(s):  
Social Development ◽  
Charitable Giving ◽  
The United States ◽  
Educational Opportunities ◽  
Great Promise ◽  
Income Gap ◽  
Supportive Environment ◽  
Performance Based Funding ◽  
Opportunity Gaps

Growing income inequality has created excessive barriers to social mobility for the poor. Charitable giving by the wealthy can reduce the societal effects of the income gap by reinvestment in public goods such as education. We apply the cipp model to investigate the role of philanthropy in advancing educational opportunities in the United States and China, using historical and contemporary cases of individual philanthropists. The findings suggest that the cases reviewed in this study created mechanisms by which to contribute to social development in their respective countries. Government policies play a key role in philanthropic development, particularly in China. It is important to continue to foster a supportive environment for the sector to grow, which may include expanding tax incentives, emphasizing performance-based funding, and eliminating administrative barriers. In short, educational philanthropy holds great promise for reducing opportunity gaps and economic inequality, by providing the key to success for future generations.

The role of digital economy in China's sustainable development in a post-pandemic environment

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Malin Song ◽  
Chenbin Zheng ◽  
Jiangquan Wang
Keyword(s):  
Economic Growth ◽  
Sustainable Development ◽  
Supply Chain ◽  
Social Development ◽  
Environmental Protection ◽  
Digital Economy ◽  
Series Data ◽  
Content Type ◽  
The Relationship

PurposeThe COVID-19 pandemic is still raging, which calls for an exploration of how to prevent and control pandemics to promote sustainable development. The purpose of this paper is to examine the role of the digital economy in sustainable development, the relationship between the two, the impacts of the outbreak on economic and social development, and changes in China's digital economy.Design/methodology/approachThe study used the time-series data from 2002 to 2019 and an unconstrained VAR model to examine the relationship between the digital economy and sustainable development before the pandemic.FindingsChina's digital economy has promoted the country's sustainable economic and social development; it has advanced rapid economic growth, improved people's living standards, increased efficient utilization of resources, and strengthened environmental protection.Research limitations/implicationsAmid the pandemic, China's digital economy developed effectively; it showed strong resilience because of its unique advantages. The digital economy in China has helped the country to control the pandemic in a short period, reduced the risk of supply chain disruption, promoted China's economic growth, and ensured the orderly operation of society. Therefore, countries worldwide are encouraged to prioritize their digital economies.Originality/valueCompared with the extant literature, this study explores the sustainable supply chain in a broader sense in the context of a pandemic, and how the supply chain is influenced by the digital economy. It not only includes the stability, resilience, and viability of the supply chain in economic development but also involves aspects of people's life, resource utilization, and environmental protection.

Exploration of Role of Economic Globalization on Human Longevity

2021 ◽  
Vol 3 (2) ◽  
pp. 223-239
Author(s):  
Bakhtawar Ijaz ◽  
Noman Arshed ◽  
Zamin Abbas ◽  
Uzma Hanif ◽  
Kamran Hameed
Keyword(s):  
Economic Growth ◽  
Social Development ◽  
Quadratic Function ◽  
Economic Globalization ◽  
Human Longevity ◽  
Kuznets Curve ◽  
Long Run ◽  
Recent Developments ◽  
Opening Up

Recent developments which were coined to the opening up of borders have attracted interest of many researchers from many disciplines. A lot of work can be observed regarding the role of globalization / internationalization on economic growth and social development, this study specifically explores the implications of globalization on the ultimate goal that is life longevity. Adapting from the Kuznets curve, this study proposed a quadratic function of economic globalization and life longevity. The results using panel the ARDL model for the SAARC region, it can be seen that expansion of trade globalization de jure and management of financial globalization de facto and de jure may help them to increase longevity in the long run.

scholarly journals The Role of HRM Policy on Academic Innovativeness Case of Business School on Saudi Arabia

2017 ◽  
Vol 9 (2) ◽  
pp. 187
Author(s):  
Wided Ragmoun ◽  
Abdullah Alwehabie
Keyword(s):  
Saudi Arabia ◽  
Social Development ◽  
Empirical Evidence ◽  
Business School ◽  
Theory Model ◽  
Academic Field ◽  
Five Dimensions ◽  
The One ◽  
Variance Explained

This study aims to understand the role of HRM on academic innovativeness. We will try to identify the adequate policy of HRM for the development of academic innovativeness.The most important is the way in which HRM will be treated as a composite construct of many practices, working in synergistic way, to generate a capacity of innovation or innovativeness according to our definition presented here.Our interest is oriented to the academic field due to importance of its role on social development. And our interest is oriented to the ability to innovate rather than innovation which still difficult to identify and measure. Academic innovativeness here is represented by five dimensions: behavior, product, process, market and strategic innovativeness.The analyze of the variance explained for our variables, provides empirical evidence that the academic innovativeness depends in majority on behavioral dimension and process. The HRM policy in this case is a distinct construction which depends on training and promotion. Added to this, some relations here must be revisited specially the link between behavior dimension of academic innovativeness and the policy of HRM as a construct.At the end of this research, we propose what we have called `the one best way` of academic innovativeness. Our theory model can be considered as user`s guide for academics to innovate based on HRM policy. 

Role of calcium channels and protein kinase C for release of norepinephrine and neuropeptide Y

1990 ◽  
Vol 259 (5) ◽  
pp. R925-R930
Author(s):  
M. Haass ◽  
C. Forster ◽  
G. Richardt ◽  
R. Kranzhofer ◽  
A. Schomig
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Calcium Channels ◽  
Calcium Channel ◽  
Neuropeptide Y ◽  
Nerve Fibers ◽  
Extracellular Calcium ◽  
Minor Effect ◽  
Kinase C

The role of calcium for the release of norepinephrine (NE, determined by high-pressure liquid chromatography) and neuropeptide Y (NPY, determined by radioimmunoassay) was investigated in guinea pig perfused hearts with intact sympathetic innervation. In the presence of extracellular calcium (1.85 mM), electrical stimulation of the left stellate ganglion (12 Hz, 1 min) induced a closely related release of NE and NPY with the molar ratio of approximately 400-600 (NE) to 1 (NPY). The stimulation-evoked overflow of both transmitters was dependent from the extracellular calcium concentration and was almost completely suppressed by calcium-free perfusion. The corelease of both transmitters was not affected by the L-type calcium channel blocker felodipine (1-10 microM). However, the overflow of NE and NPY was markedly attenuated by the unselective calcium antagonist flunarizine (1-10 microM) and completely prevented by the neuronal (N-type) calcium channel blockers omega-conotoxin (1-100 nM) and cadmium chloride (10-100 microM), indicating a key role for N-type calcium channels in the exocytotic release of transmitters from cardiac sympathetic nerve fibers. Possibly due to unspecific actions, such as interference with sodium channels or uptake1-blocking properties, the phenylalkylamines verapamil (0.01-10 microM) and gallopamil (1-10 microM) reduced NPY overflow with only a minor effect on NE overflow. The stimulation-induced transmitter release was increased up to twofold by activation of protein kinase C (phorbol 12-myristate 13-acetate, 3 nM-3 microM) and completely suppressed by inhibition of protein kinase C (polymyxin B, 100 microM).(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals The role of communication marketing media campaign programs for Sudanese childs issues

2021 ◽  
Vol 6 (8) ◽  
pp. 255-290
Author(s):  
Dr. Amal Mahmoud fadol mukhtar
Keyword(s):  
Social Development ◽  
Social Economic ◽  
Social Awareness ◽  
Basic Question ◽  
Media Campaign ◽  
Information Campaigns ◽  
Simple Observation ◽  
The Family

This research tackles the role of communication in social marketing of child issues in the Sudan, a case study on the ministry of Social Development in Khartoum state. The purpose of this research is to recognize the communication role done by General Administration of  Information and Social Awareness of  the ministry of  Social Development in marketing the programs of social campaigns of the Sudanese child represented in social patronage, sponsorship and supporting and protection, include the specific social, economic and political aspects, as health, education, providing security and settlement. The research tried to answer a number of questions, one of them is a basic question. What is the number and size of information campaigns implemented at the period from August 2019 to August 2020? The researcher used the descriptive methodology besides the methodology of status study. And the researcher depends on questionnaire, the (systemized) interview form, (not systemized) interview form, and the simple observation . Findings: The research concluded to a number of findings, the most important of them are: 1.There is a malfunction in the efficiency of communication with the General Administration of Information and Social Awareness of the ministry.  The cause of this is lack of enough trained information cadre, and lack of enough money be specified to the campaign. 2.The subjects and Programs come within the campaign do not cover all sectors of children but concentrate on the children of hard circumstances. 3.The number of information campaigns implemented at the period from 2019 to 2020 are two: a campaign  on orphanages (Halima Al-Saadaya) and a campaign to patronize the children of streets (who lost the family caring).

scholarly journals Gastroesophageal reflux disease: new approaches to optimizing pharmacotherapy

2021 ◽  
pp. 30-37
Author(s):  
D. N. Andreev ◽  
A. V. Zaborovsky ◽  
E. G. Lobanova
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Barrier Properties ◽  
Nerve Fibers ◽  
Esophageal Mucosa ◽  
Mucosal Permeability ◽  
Other Substances ◽  
Maintenance Of Remission

Proton pump inhibitors (PPIs) are baseline drugs for induction and maintenance of remission in gastroesophageal reflux disease (GERD). PPIs have proven to be highly effective in healing esophageal mucosal lesions and relieving the symptoms of the disease in most cases. However, according to the literature data, the incidence rate of clinical ineffectiveness of PPIs in the form of partial or complete persistence of current symptoms during administration of standard doses of PPIs ranges from 10 to 40%. Optimization of GERD therapy in PPI refractory patients is a significant challenge. In most cases, experts advise to increase a dose / dosage frequency of PPIs, switch to CYP2C19-independent PPIs (rabeprazole, esomeprazole, dexlansoprazole), add an esophagoprotective or promotility agents to therapy. At the same time, these recommendations have a limited effect in some patients, which opens up opportunities for looking for new solutions related to the optimization of GERD therapy. Today there is growing evidence of the relevance of the role of disruption of the cytoprotective and barrier properties of the esophageal mucosa in the genesis of GERD and the formation of refractoriness. Intercellular contacts ensure the integrity of the barrier function of the esophageal mucosa to protect it from various exogenous intraluminal substances with detergent properties. Acid-peptic attack in patients with GERD leads to alteration of the expression of some tight junction proteins in epithelial cells of the esophageal mucosa. The latter leads to increased mucosal permeability, which facilitates the penetration of hydrogen ions and other substances into the submucosal layer, where they stimulate the terminals of nerve fibers playing a role in the induction and persistence of the symptoms of the disease. The above evidence brought up to date the effectiveness study of the cytoprotective drugs with tropism to the gastrointestinal tract, as part of the combination therapy of GERD.

Sign in / Sign up

Export Citation Format

Share Document