The effect of programmed cryopreservation on immunogenicity of bladder mucosa in New Zealand rabbits

Cryobiology ◽  
2012 ◽  
Vol 64 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Yong Lu ◽  
Bingkun Li ◽  
Xiang Wang ◽  
Jie Zheng ◽  
Jinxian Pu ◽  
...  
Keyword(s):  
New Zealand ◽  
Bladder Mucosa ◽  
New Zealand Rabbits

Antiurolithiatic effect of Cymbopogon Proximus, Alhagi Maurorum, on Sulfadimidine induced urolithiasis in male New Zealand rabbits

2019 ◽  
Vol 20 (1) ◽  
pp. 12-18
Author(s):  
Sameh El-Nabtity
Keyword(s):  
New Zealand ◽  
Intramuscular Injection ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
Aqueous Extracts ◽  
Blood And Urine Samples ◽  
Group 2 ◽  
New Zealand Rabbits ◽  
Group 1

The present study aimed to investigate the prophylactic effect of Cymbopogon proximus and Alhagi maurorum on Sulfadimidine induced urolithiasis in rabbits . Thirty New Zealand male rabbits were allocated into six equal groups (each of five): Group (1) was used as a negative control. Group(2) were administered sulfadimidine (200mg/kg) by intramuscular injection.Groups(3) and (4) were administered sulfadimidine(200mg/kg) by intramuscular injection and 330mg/kg of Cymbopogon proximus alcoholic and aqueous extracts respectively orally.Groups(5) and (6) were administered sulfadimidine(200mg/kg) by intramuscular injection and 400mg/kg of Alhagi maurorum alcoholic and aqueous extracts respectively orally. The period of experiment was 10 days. Blood and urine samples were collected from rabbits on the 10th day. The results recorded a significant decrease in serum creatinine, urea, uric acid and crystalluria in Cymbopogon proximus and Alhagi maurorum groups compared to sulfadimidine treated group.We conclude that Cymbopogon proximus and Alhagi maurorum have a nephroprotective and antiurolithiatic effects against sulfadimidine induced crystalluria.

Plasma bioactive LH and testosterone profiles in male New Zealand rabbits experimentally infected with Schistosoma mansoni

Acta Tropica ◽  
2004 ◽  
Vol 92 (3) ◽  
pp. 165-172 ◽  
Author(s):  
Y.S. Kasilima ◽  
E.O. Wango ◽  
C.S. Kigondu ◽  
B.M. Mutayoba ◽  
M. Nyindo
Keyword(s):  
New Zealand ◽  
Schistosoma Mansoni ◽  
New Zealand Rabbits

scholarly journals A Comparative Study of Bioartificial Bone Tissue Poly-L-lactic Acid/Polycaprolactone and PLLA Scaffolds Applied in Bone Regeneration

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Weizong Weng ◽  
Shaojun Song ◽  
Liehu Cao ◽  
Xiao Chen ◽  
Yuanqi Cai ◽  
...  
Keyword(s):  
Lactic Acid ◽  
New Zealand ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Bone Defect ◽  
Mineral Density ◽  
Group A ◽  
Repair Bone Defect ◽  
Group B ◽  
New Zealand Rabbits

Bioartificial bone tissue engineering is an increasingly popular technique to repair bone defect caused by injury or disease. This study aimed to investigate the feasibility of PLLA/PCL (poly-L-lactic acid/polycaprolactone) by a comparison study of PLLA/PCL and PLLA scaffolds applied in bone regeneration. Thirty healthy mature New Zealand rabbits on which 15 mm distal ulna defect model had been established were selected and then were divided into three groups randomly: group A (repaired with PLLA scaffold), group B (repaired with PLLA/PCL scaffold), and group C (no scaffold) to evaluate the bone-remodeling ability of the implants. Micro-CT examination revealed the prime bone regeneration ability of group B in three groups. Bone mineral density of surgical site in group B was higher than group A but lower than group C. Meanwhile, the bone regeneration in both groups A and B proceeded with signs of inflammation for the initial fast degradation of scaffolds. As a whole, PLLA/PCL scaffoldsin vivoinitially degrade fast and were better suited to repair bone defect than PLLA in New Zealand rabbits. Furthermore, for the low mineral density of new bone and rapid degradation of the scaffolds, more researches were necessary to optimize the composite for bone regeneration.

Ameliorative effect of fermented Pentaclethra macrophylla (African oil bean seed) on high fat diet and sucrose drink induced metabolic syndrome in male New Zealand rabbits.

2019 ◽  
Vol 5 (1) ◽  
pp. 42-48
Author(s):  
Nwozo Onyenibe ◽  
Daramola Victoria ◽  
Nwawuba Udogadi
Keyword(s):  
Metabolic Syndrome ◽  
New Zealand ◽  
Normal Control ◽  
High Fat Diet ◽  
Bean Seed ◽  
High Fat ◽  
Treatment And Prevention ◽  
Elevated Glucose ◽  
Ameliorative Effect ◽  
New Zealand Rabbits

The consumption of nutraceuticals has become progressively popular in improving health, as well as disease treatment and prevention. The aim of this study is to evaluate the ameliorative effect of fermented Pentaclethra macrophylla (African oil bean) seed on high fat diet and sucrose drink induced metabolic syndrome in male New Zealand rabbits. All experimental procedures were carried using standard methods. A total of twenty (20) rabbits were used for this study, the animals were randomly grouped into five (5) groups with four (4) animals each. Metabolic syndrome risk factors obesity, hypertension, dyslipidemia and hyperglycemia were determined. HFD+30%SUC had over 1500g body weight (bwt) and fasting blood sugar (FBS) 239.50±5.74 mg/dl  relative to the normal control with 1000±6.73g and 77.00±5.94 respectively whereas ND+30%SUC had lower FBS (l172.50±2.52) compared to HFD+30%SUC. There was a significant p<0.05 increase in body weights in treated groups with 1274±11.19g, 1282.75±4.99g, 1285±4.76g and FBS levels in mg/dL198.25±4.79, 198.75±8.06, 200±3.74 in rabbits  compared to untreated HFD+30%SUC. Glycated hemoglobin, and ?-Amylase were significantly p<0.05 elevated, glucose-6-phosphate dehydrogenase levels were significantly p<0.05 reduced, lipid profile markers (HDL, TRIG & CHOL), electrolytes (sodium, potassium, calcium), urea and creatinine levels were significantly p<0.05 altered in HFD+30%SUC exposed group relative to the normal control and ND+30%SUC. However, dietary supplementation with fermented Pentaclethra macrophylla seeds caused weight, FBS, serum lipid reduction and potentiated electrolyte, urea and creatinine levels. Therefore, according to our results, fermented Pentaclethra macrophylla seed is an excellent nutraceutical and its consumption should be encouraged in modifying high fat and elevated intake of sucrose in rabbit

scholarly journals L-asparaginase: acute effects on protein synthesis in rabbits with normal and increased fibrinogen production

Blood ◽  
1984 ◽  
Vol 63 (4) ◽  
pp. 823-827 ◽  
Author(s):  
BM Alving ◽  
CF Barr ◽  
DB Tang
Keyword(s):  
Protein Synthesis ◽  
New Zealand ◽  
Amino Acid ◽  
Plasma Proteins ◽  
Serum Proteins ◽  
Intravenous Dose ◽  
Single Intravenous Dose ◽  
Acute Effects ◽  
Abnormal Rate ◽  
New Zealand Rabbits

Abstract The acute effects of a single intravenous dose of L-asparaginase on protein synthesis were studied in normal rabbits and in animals that had received turpentine to stimulate fibrinogen production. Male New Zealand rabbits received L-asparaginase (500 U/kg) 16 hr before the injection of the radiolabeled amino acid [75Se]selenomethionine (75SeM). Incorporation of 75SeM into fibrinogen and serum proteins in the L-asparaginase-treated rabbits was the same as for saline-treated controls, with fibrinogen representing approximately 5% of the labeled plasma proteins. In turpentine-treated rabbits, the maximal incorporation of 75SeM into serum proteins remained unchanged, whereas 75SeM-fibrinogen increased sixfold and accounted for 25% of the labeled proteins. Animals that received L-asparaginase at the same time as turpentine or 14 hr later showed significant decreases in synthesis of both serum proteins and fibrinogen. 75SeM-fibrinogen that was purified from L-asparaginase-treated rabbits underwent normal catabolism when injected into normal recipient rabbits. These data indicate that L- asparaginase can acutely cause partial inhibition of both serum protein and fibrinogen synthesis when administered to rabbits shortly before or during a period of increased fibrinogen production. Fibrinogen that is synthesized in the presence of L-asparaginase does not have an abnormal rate of catabolism.

scholarly journals Comparison of 2 portable human glucometers for the measurement of blood glucose concentration in White New Zealand rabbits

2020 ◽  
Vol 32 (5) ◽  
pp. 683-688
Author(s):  
Kassy G. Silva ◽  
Isabella Rotta ◽  
Leandro B. Costa ◽  
Cristina S. Sotomaior
Keyword(s):  
Blood Glucose ◽  
New Zealand ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Pearson Correlation ◽  
Reference Method ◽  
Mean Difference ◽  
Chemical Analyzer ◽  
Error Grid ◽  
New Zealand Rabbits

We compared measurements of blood glucose concentrations in 30 healthy adult White New Zealand rabbits using 2 commercial portable glucometers (PGM1 and PGM2) and a laboratory chemical analyzer. Results were analyzed with Pearson correlation, Passing–Bablok regression analysis, Bland–Altman analysis, and a modified error grid. Measurements with PGM1 were significantly correlated ( r = 0.37) with those obtained from the laboratory reference method (RM); Bland–Altman and Passing–Bablok analyses indicated no significant systematic or proportional differences (mean difference of −0.26, 95% CI of mean difference of −0.54 to 0.01, and LOA of −1.70 to 1.17); and error grid resulted in 100% of measurements in zone A. No significant correlation ( r = −0.05) was detected between PGM2 and RM; Bland–Altman and Passing–Bablok analyses results indicated a mean difference of 2.14, 95% CI of mean difference of 1.67–2.60, and limit of agreement of −0.32 to 4.59, which overestimated blood glucose concentration, with 53% of glucose measurements in error grid zone A and 47% in zone B. PGM1 was considered accurate in normoglycemic rabbits, whereas the use of PGM2 could result in overestimations of glycemia.

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