2-cm versus 4-cm surgical excision margin for thick (>2 mm) primary malignant melanoma: long-term follow-up of a multicenter randomized trial

2020 ◽  
Vol 46 (2) ◽  
pp. e15-e16
Author(s):  
Jüri Teras ◽  
Deborah Utjés ◽  
Jonas Malmstedt ◽  
Krzysztof Drzewiecki ◽  
Hans Petter Gullestad ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Randomized Trial ◽  
Surgical Excision ◽  
Primary Malignant Melanoma ◽  
Excision Margin ◽  
Multicenter Randomized Trial ◽  
Long Term Follow Up

A randomized trial of levamisole versus placebo as adjuvant therapy in malignant melanoma.

1991 ◽  
Vol 9 (5) ◽  
pp. 736-740 ◽  
Author(s):  
L E Spitler
Keyword(s):  
Malignant Melanoma ◽  
Adjuvant Therapy ◽  
Randomized Trial ◽  
Control Groups ◽  
Disease Free Interval ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
And Control

We conducted a long-term follow-up (median, 10.5 years) of patients included in a randomized trial of levamisole versus placebo as surgical adjuvant therapy in 203 patients with malignant melanoma. Of the patients randomized, 104 received levamisole, and 99 received placebo. The results show that there is no difference between the treatment and control groups with regard to any of the three end points analyzed. These included disease-free interval, time to appearance of visceral metastasis, and survival. Moreover, there was no significant difference between the treatment and control groups after adjusting for age, sex, or stage of disease.

Long-Term Follow-up of the First Randomized Trial Using Neoadjuvant Chemotherapy in Stage Ib Squamous Carcinoma of the Cervix: The Final Results

1997 ◽  
Vol 67 (1) ◽  
pp. 61-69 ◽  
Author(s):  
Juan E. Sardi ◽  
Adolfo Giaroli ◽  
Carlos Sananes ◽  
Marta Ferreira ◽  
Alejandro Soderini ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Randomized Trial ◽  
Squamous Carcinoma ◽  
Stage Ib ◽  
Long Term Follow Up

Extramedullary Plasmacytoma of The Frontal Sinus: A Case Report

FACE ◽  
2021 ◽  
pp. 273250162110536
Author(s):  
Joshua Harrison ◽  
Samantha Marley ◽  
Shawhin Shahriari ◽  
Christian Bowers ◽  
Anil Shetty
Keyword(s):  
Frontal Sinus ◽  
Surgical Excision ◽  
Extramedullary Plasmacytoma ◽  
High Rate ◽  
Solitary Plasmacytoma ◽  
Case Presentation ◽  
Long Term Follow Up ◽  
History Of

We report a rare case of an extramedullary plasmacytoma (EMP) in the frontal sinus with an indolent clinical presentation. Although a history of trauma was absent, the initial diagnosis was a mucocele, based on the radiological findings. Upon surgical excision, the patient was found to have an EMP. EMP, a form of solitary plasmacytoma, has a significantly high rate of conversion to multiple myeloma. This mandates long-term follow-up, even after successful radiotherapy and/or resection. While radiation therapy is generally considered a first line treatment for EMP, surgical intervention may provide optimal treatment in complicated cases. This case presentation highlights the prognosis of patients diagnosed with EMP.

LONG-TERM FOLLOW UP OF A RANDOMIZED TRIAL COMPARING THE BEGER AND FREY PROCEDURE FOR PATIENTS SUFFERING FROM CHRONIC PANCREATITIS.

Pancreas ◽  
2004 ◽  
Vol 29 (4) ◽  
pp. 332
Author(s):  
T. Strate ◽  
Z. Taherpour ◽  
C. Bloechle ◽  
O. Mann ◽  
J.P. Bruhn ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Randomized Trial ◽  
Frey Procedure ◽  
Long Term Follow Up
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