Projection of temperature-related mortality due to cardiovascular disease in beijing under different climate change, population, and adaptation scenarios

This article presents a customized system dynamics model to facilitate the informed development of policy for urban heat island mitigation within the context of future climate change, and with special emphasis on the reduction of heat-related mortality. The model incorporates a variety of components (incl.: the urban heat island effect; population dynamics; climate change impacts on temperature; and heat-related mortality) and is intended to provide urban planning and related professionals with: a facilitated means of understanding the risk of heat-related mortality within the urban heat island; and location-specific information to support the development of reasoned and targeted urban heat island mitigation policy.

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Heat-related mortality under climate change and the impact of adaptation through air conditioning: A case study from Thessaloniki, Greece

Environmental Research ◽

10.1016/j.envres.2021.111285 ◽

2021 ◽

pp. 111285

Author(s):

Panayiotis Kouis ◽

Kyriaki Psistaki ◽

George Yiallouros ◽

Antonis Michanikou ◽

Maria G. Kakkoura ◽

...

Keyword(s):

Climate Change ◽

Air Conditioning ◽

The Impact ◽

Related Mortality

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Type 2 diabetes in patients with end‐stage kidney disease: influence on cardiovascular disease‐related mortality risk

The Medical Journal of Australia ◽

10.5694/mja18.00195 ◽

2018 ◽

Vol 209 (10) ◽

pp. 440-446 ◽

Cited By ~ 10

Author(s):

Wai H Lim ◽

David W Johnson ◽

Carmel Hawley ◽

Charmaine Lok ◽

Kevan R Polkinghorne ◽

...

Keyword(s):

Type 2 Diabetes ◽

Cardiovascular Disease ◽

Kidney Disease ◽

Mortality Risk ◽

End Stage Kidney Disease ◽

End Stage ◽

Related Mortality

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Projecting future climate change impacts on heat-related mortality in large urban areas in China

Environmental Research ◽

10.1016/j.envres.2018.01.047 ◽

2018 ◽

Vol 163 ◽

pp. 171-185 ◽

Cited By ~ 19

Author(s):

Ying Li ◽

Ting Ren ◽

Patrick L. Kinney ◽

Andrew Joyner ◽

Wei Zhang

Keyword(s):

Climate Change ◽

Urban Areas ◽

Climate Change Impacts ◽

Future Climate ◽

Future Climate Change ◽

Related Mortality

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Climate change adaptation networks for small and medium-sized cities

SN Social Sciences ◽

10.1007/s43545-021-00267-7 ◽

2021 ◽

Vol 1 (11) ◽

Author(s):

Simone Häußler ◽

Wolfgang Haupt

Keyword(s):

Climate Change ◽

Climate Change Adaptation ◽

Federal State ◽

Research Approach ◽

Regional Network ◽

Participatory Action ◽

Climate Risks ◽

Action Research Approach ◽

Response Systems ◽

Adaptation Scenarios

AbstractCities are particularly vulnerable to the impacts of climate change. Many larger cities have identified the potential impacts of different climate change adaptation scenarios. However, their smaller and medium-sized counterparts are often not able to address climate risks effectively due to a lack of necessary resources. Since a large number of cities worldwide are indeed small and medium-sized, this lack of preparedness represents a crucial weakness in global response systems. A promising approach to tackling this issue is to establish regional municipal networks. Yet, how might a regional network for small and medium-sized cities be systematically designed and further developed? Focussing on the German federal state of Baden-Wuerttemberg, we have explored this question by applying a participatory action research approach. As part of our research, we established a regional network framework for small and medium-sized cities. The framework supports small and medium-sized cities in identifying key regional actors, while taking local and regional contextual factors into account. Based on our findings, we suggest that other small and medium sized cities follow these steps: develop the knowledge base; build the network; and transfer and consolidate knowledge.

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The Association of Atherosclerotic Cardiovascular Disease and Statin Use With Inflammation and Treatment Outcomes in Tuberculosis

10.21203/rs.3.rs-520059/v1 ◽

2021 ◽

Author(s):

Vignesh Chidambaram ◽

Jennie Ruelas Castillo ◽

Amudha Kumar ◽

Justin Wei ◽

Siqing Wang ◽

...

Keyword(s):

Cardiovascular Disease ◽

Linear Regression Analysis ◽

Elevated Serum ◽

University Hospital ◽

Sputum Smear ◽

Atherosclerotic Cardiovascular Disease ◽

All Cause Mortality ◽

Multivariable Linear Regression Analysis ◽

Related Mortality ◽

Statin Use

Abstract Objective: Tuberculosis (TB) and atherosclerotic cardiovascular disease (ASCVD) have a close epidemiological and pathogenetic overlap. Thus, it becomes essential to understand the relationship between ASCVD and TB outcomes.Methods:From our retrospective cohort on drug-susceptible TB patients at the National Taiwan University Hospital, we assessed the association of pre-existing ASCVD (coronary artery disease (CAD) and atherothrombotic stroke (ATS)) with 9-month all-cause and infection-related mortality and the extent of mediation by systemic inflammatory markers. We determined the effect of pre-existing ASCVD on 2-month sputum microbiological status. Among ASCVD patients, we assessed the association of statin use on mortality.Results:Nine-month all-cause mortality was higher in CAD patients with prior acute myocardial infarction (CAD+AMI+) (adjusted HR 2.01, 95%CI 1.38-3.00) and ATS patients (aHR 2.79, 95%CI 1.92-4.07) and similarly, for infection-related mortality was higher in CAD+AMI+ (aHR 1.95, 95%CI 1.17-3.24) and ATS (aHR 2.04, 95%CI 1.19-3.46) after adjusting for confounding factors. Pre-existing CAD (AMI- or AMI+) or ATS did not change sputum culture conversion or sputum smear AFB positivity at 2 months. The CAD+AMI+ group had significantly higher levels of CRP at TB diagnosis in the multivariable linear regression analysis (Adjusted B(SE) 1.24(0.62)). CRP mediated 66% (p=0.048) and 25% (p=0.033) of the association all-cause mortality with CAD+AMI- and CAD+AMI+, respectively. ConclusionsIn summary, patients with ASCVD have higher hazards of 9-month all-cause and infection-related mortality, with elevated serum inflammation mediating one to three-quarters of this association when adjusted for confounders. Statin use was associated with lower all-cause mortality among patients with ASCVD.

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Corrigendum to: The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study

European Heart Journal ◽

10.1093/eurheartj/ehz028 ◽

2019 ◽

Vol 40 (14) ◽

pp. 1157-1157

Keyword(s):

Cardiovascular Disease ◽

Osteoporotic Fractures ◽

Sleep Apnoea ◽

Health Study ◽

Heart Health ◽

Related Mortality

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All-Cause and Cardiovascular Disease Mortality Among Breast Cancer Survivors in CLUE II, a Long-Standing Community-Based Cohort

JNCI Journal of the National Cancer Institute ◽

10.1093/jnci/djaa096 ◽

2020 ◽

Cited By ~ 1

Author(s):

Cody Ramin ◽

Marcy L Schaeffer ◽

Zihe Zheng ◽

Avonne E Connor ◽

Judith Hoffman-Bolton ◽

...

Keyword(s):

Breast Cancer ◽

Cardiovascular Disease ◽

Estrogen Receptor ◽

General Population ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

Risk Of Death ◽

Free Women ◽

Related Mortality ◽

Cvd Mortality

Abstract Background There is growing evidence that breast cancer survivors have higher cardiovascular disease (CVD) mortality relative to the general population. Information on temporal patterns for all-cause and CVD mortality among breast cancer survivors relative to cancer-free women is limited. Methods All-cause and CVD-related mortality were compared in 628 women with breast cancer and 3140 age-matched cancer-free women within CLUE II, a prospective cohort. We calculated adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox proportional hazards regression for all-cause mortality, and Fine and Gray models for CVD-related mortality to account for competing risks. Results Over 25 years of follow-up, 916 deaths occurred (249 CVD related). Breast cancer survivors had an overall higher risk of dying compared with cancer-free women (HR = 1.79, 95% CI = 1.53 to 2.09) irrespective of time since diagnosis, tumor stage, estrogen receptor status, and older age at diagnosis (≥70 years). Risk of death was greatest among older survivors at more than 15 years after diagnosis (HR = 2.69, 95% CI = 1.59 to 4.55). CVD (69.1% ischemic heart disease) was the leading cause of death among cancer-free women and the second among survivors. Survivors had an increase in CVD-related deaths compared with cancer-free women beginning at 8 years after diagnosis (HR = 1.65, 95% CI = 1.00 to 2.73), with the highest risk among older survivors (HR = 2.24, 95% CI = 1.29 to 3.88) and after estrogen receptor-positive disease (HR = 1.85, 95% CI = 1.06 to 3.20). Conclusions Breast cancer survivors continue to have an elevated mortality compared with the general population for many years after diagnosis. Preventing cardiac deaths, particularly among older breast cancer patients, could lead to reductions in mortality.

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Statistical Modelling of Temperature-Attributable Deaths in Portuguese Metropolitan Areas under Climate Change: Who Is at Risk?

Atmosphere ◽

10.3390/atmos11020159 ◽

2020 ◽

Vol 11 (2) ◽

pp. 159

Author(s):

Mónica Rodrigues ◽

Paula Santana ◽

Alfredo Rocha

Keyword(s):

Climate Change ◽

Metropolitan Area ◽

Age Groups ◽

Circulatory System ◽

Statistical Modelling ◽

Attributable Mortality ◽

Historical Period ◽

Age Group ◽

Circulatory System Diseases ◽

Related Mortality

Several studies emphasize that temperature-related mortality can be expected to have differential effects on different subpopulations, particularly in the context of climate change. This study aims to evaluate and quantify the future temperature-attributable mortality due to circulatory system diseases by age groups (under 65 and 65+ years), in Lisbon metropolitan area (LMA) and Porto metropolitan area (PMA), over the 2051–2065 and 2085–2099 time horizons, considering the greenhouse gas emissions scenario RCP8.5, in relation to a historical period (1991–2005). We found a decrease in extreme cold-related deaths of 0.55% and 0.45% in LMA, for 2051–2065 and 2085–2099, respectively. In PMA, there was a decrease in cold-related deaths of 0.31% and 0.49% for 2051–2065 and 2085–2099, respectively, compared to 1991–2005. In LMA, the burden of extreme heat-related mortality in age group 65+ years is slightly higher than in age group <65 years, at 2.22% vs. 1.38%, for 2085–2099. In PMA, only people aged 65+ years showed significant temperature-related burden of deaths that can be attributable to hot temperatures. The heat-related excess deaths increased from 0.23% for 2051–2065 to 1.37% for 2085–2099, compared to the historical period.

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