Ethno-cultural predictors, which determine features of cognitive behavioral therapy of persons with PTSD

2017 ◽  
Vol 41 (S1) ◽  
pp. S518-S518
Author(s):  
M. Sulaimanova ◽  
R. Sulaimanov

ObjectiveStudy of the predictors of ethno-cultural adaptation among male population with PTSD.Materials and methodsWe examined 72 males (age: 18–52) with PTSD (F43.1), acquired in interethnic Kyrgyz-Uzbek conflict. In the process of CBT 3 psychotherapeutic groups were formed: 1st (2 homogenous subgroups) included 24 ethnic Kyrgyz, 2nd (2 homogenous subgroups): 24 ethnic Uzbeks, 3rd (2 heterogeneous subgroups): 12 Uzbeks, 12 Kyrgyz.MethodsSemi-formalized interview, standardized scales for evaluating PTSD, anxiety, depression, aggression, loneliness.ResultsHigh levels of aggressiveness among Kyrgyz: 52.4, among Uzbeks: 51.7 (P < 0.05), loneliness among Kyrgyz: 38.9, among Uzbeks: 46.2 (P < 0.05), anxiety among Kyrgyz: 48.8, among Uzbeks: 52.4 (P < 0.05), depression among Kyrgyz: 57.5, among Uzbeks: 61.1 (P < 0.05) are mutually conditioning factors. In the CBT process, the values decreased: in 1st group anxiety level to 44.4 (P < 0.05), depression: 54.2 (P < 0.05); aggressiveness: 48.2 (P < 0.05), loneliness: 38.4 (P < 0.05); in 2nd: anxiety: 49.4 (P < 0.05), depression: 59.8 (P < 0.05), aggressiveness: 47.3 (P < 0.05), loneliness: 42.4 (P < 0.05); in 3rd: anxiety: 41,1 (P < 0.05), depression: 52.2 (P < 0.05), aggressiveness: 46.5 (P < 0.05), loneliness: 35.5 (P < 0.05).ConclusionsHigh levels of aggressiveness and loneliness among the respondents of both ethnic groups are the predictors of PTSD. Emphasized anxiety-phobic (group 1) and anxiety-depressive (group 2) disorders are the activating mechanisms of adaptation processes in micro-society (psychotherapeutic group). Dominating anxiety-phobic disorders (group 1), anxiety-depressive disorders (group 2), and their entanglement with values of aggressiveness and loneliness determine development and stability of clinical-psychopathologic manifestations as dysthymic disorders, which is an indicator for biological treatment. Heterogeneous group, as a result of CBT, has shown activation of psychological adaptation mechanism by the dissociative type, which is one of the mechanisms of ethno-cultural adaptation and requires subsequent research.Disclosure of interestThe authors have not supplied their declaration of competing interest.

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Demenko ◽  
G.A Chumakova

Abstract Background Mental disorders in patients with cardiovascular disease have a significant impact on the course, the prognosis of the underlying disease and quality of life (QOL). Objective We aimed to examine the prevalence of anxiety and depressive disorders and their impact on the quality of life in patients with atrial fibrillation (AF). Materials and methods In 52 with permanent AF and 50 with paroxysmal AF patients, we administered the depression scale Tsung, the scale of situational anxiety (SA) and personal anxiety (PA) Spielberger-Hanin; QOL was assessed the SF-36 quality of life assessment scale. Correlation analysis using Spearman's rank correlation coefficient. Results The prevalence symptoms mild depression situational or neurotic genesis was 21.1% (12 patients) in Group 1 and 12.0% (6 patients) in Group 2 (p&gt;0.05). Subdepressive state was two percents of patients in Group 1 and Group 2. The incidence SA was 59.6% (31 patients) in Group 1 and 52.0% (26 patients) in Group 2. The incidence PA was 74.0% (37 patients) in Group 2 and 67.3% (35 patients) in Group 1. The average score the physical component of health (PCH) was 29,8±4,3 in Group 1, the mental component of health (MCH) – 49.5±7.4 points; p&lt;0.05. In Group 2: PCH – 44.8±6.6 points, MCH – 26.6±7.5 points; p&lt;0.05. Correlation analysis showed negative strong correlations between SA and MCH (r=−0.64, p=0.0005) and between PA and MCH (r=−0.69, p&lt;0.0001), between SA and PCH (r=−0.71, p=0.0001), between depression and PCH (r=−0.69, p=0.023). Negative statistically significant correlation between depression and MCH (r=−0.69, p=0.54) and negative medium correlation between depression and PCH (r=−0.64, p=0.23). Conclusion These findings suggest that we did not identify patients with symptoms of a true depressive (that can cause pseudodementia and influenced to complete tests). 16.5% patients with AF had mild depression of situational or neurotic genesis. Depression may be a pathogenetic factor of AF or develop because of paroxysms AF – psychological stress. More than 50% patients in Group 1 and Group 2 had an increased anxiety score. SA is more common in patients with permanent AF, probably because older people difficult to adapt to a new situation. PA is more common in patient with paroxysmal AF, probably because disease is sudden and causes anxiety. The PCH of QOL is more impairment in patients with permanent AF, because complications (for example heart failure) impairment physical activity. However, PCH also reduced in patient with paroxysmal AF, because disease is sudden may occur during physical activity. The MCH of QOL is more impairment in patients with paroxysmal AF, because waiting attack effect on mental health and social functioning. An increased level of anxiety and depression negatively affected the mental and physical health of patients with AF. Funding Acknowledgement Type of funding source: None


1999 ◽  
Vol 21 (21) ◽  
pp. 97
Author(s):  
Andrea V. Nummer ◽  
Luis Eduardo S. Robaina ◽  
Marcos Geovane Berger

Weathering processes and jointing degree are the conditioning factors for rock falI.The fractured volcanic lithologies from Santa Maria, RS, Brazil, were studied along the BR 158 road. Data was gathered through the Scanline method from BRADY & BROWN (1985) and analyzed by vector statistics.Six main jointing groups were defined, associated to rock cooling and shrinking. Main attitudes are: Group 1: 348;83; Group 2: 174;82; Group 3: 85;76; Group 4: 265;75; Group 5: 300;42 and Group 6: 121 ;53.


Neurosurgery ◽  
1982 ◽  
Vol 11 (1_pt_1) ◽  
pp. 25-32 ◽  
Author(s):  
Dominic Foo ◽  
Alain B. Rossier

Abstract Five patients with vertebral fracture and spinal epidural hematoma (SEH) are described. Another 58-year-old man developed a post-traumatic SEH without bony damage. From the literature, 38 patients (31 male, 4 female, and 3 unknown) were collected. Ankylosing spondylitis or rheumatoid arthritis was noted in 9 of 12 subjects between 50 and 75 years of age. Two groups of patients were identified: Group 1—16 patients with spinal fracture (aged 23 to 63 years), and Group 2—22 patients without spinal fracture (the age was less than 18 years in 12 subjects). In Group 2, a coagulation defect or spinal epidural vascular malformation resulted in a SEH in 6 patients. The preoperative myelopathy was complete in 3 patients each from Group 1 (23.1%) and Group 2 (16.7%). Of the 31 patients operated upon, 9 of the 13 from Group 1 (69.3%) and 6 of the 18 from Group 2 (33.3%) underwent laminectomy within I week after the onset of symptoms. Postoperative neurological return was observed in 38.5% (5 of 13) and 88.9% (16 of 18) of these two groups of patients, respectively. Post-traumatic SEHs, predominant in the male population, are often associated with vertebral disease in elderly patients. In the very young patient, there is usually no fracture/dislocation of the spine. A predisposing lesion may be present when spinal fracture is not evident. The prognosis after surgical intervention is better in patients without spinal fracture than in those with vertebral damage, probably because of less contusion to the spinal cord and the presence of very young subjects in the former group of patients.


Author(s):  
L.N. Gumenyuk ◽  
L.I. Seytumerova ◽  
A.A. Serafimova ◽  
A.V. Yatsiv

Chronic postoperative pain is one of the urgent medical and social problems of operative gynecology. The problem is preconditioned by a high prevalence rate, a significant impact on the outcomes of operative therapy and, as a consequence, patients’ quality of life. The goal of the paper is to study the role of preoperative neurotransmitter and psychoemotional dysfunctions in the development of postoperative chronic pain syndrome in an operative gynecology center. Materials and Methods. The study enrolled 156 patients aged 18–45 years who underwent planned surgical treatment for gynecological pathology. Patients were subsequently divided into 2 groups: Group 1 – women with postoperative chronic pain syndrome; Group 2 – women without chronic postoperative pain syndrome. The authors conducted general clinical examination, and also determined the levels of g-aminobutyric acid and β-endorphin in serum of patients using enzyme-linked immunosorbent assay. A visual analogue scale was used to assess quantitative characteristics of pain syndrome. Qualitative characteristics of pain syndrome were assessed according to the McGill Pain Questionnaire. HAM-A and HDRS were used to assess psychoemotional state. Results. Postoperative chronic pain was observed in 39.7 % of patients 12 months after surgery. In the preoperative period, a pain syndrome was registered in all patients. However, there were no significant intergroup differences in its severity. Statistically significant predominance of the affective scale indicators was revealed in the pain syndrome structure in Group 1, while Group 2 demonstrated predominance of the sensory scale indicators (p=0.003). Group 1 demonstrated more pronounced changes in GABA and β-endorphin levels. An inverse correlation was found between the level of β-endorphin and the affective and evaluative McGill questionnaire scales. Various affective pathologies were verified in Group 1. However, depressive disorders dominated. Group 2 demonstrated only subdepression and individual clinically unformed anxiety symptoms. The authors found out depressive disorder correlation with the severity of preoperative pain syndrome according to visual-analogue scale, McGill questionnaire affective scale, and β-endorphin concentration. Conclusion. Neurotransmitter disorders and psychological dysfunctions affect the formation of postoperative chronic pain syndrome. There is a correlation between chronic postoperative pain syndrome, preoperative β-endorphin concentration (r=-0.70; p=0.028), and the severity of depressive disorders (r=0.65; p=0.012), which confirms their role as non-specific prognostic markers while monitoring the postoperative chronic pain syndrome. Keywords: gynecological pathology, postoperative chronic pain syndrome, neurotransmitters, affective disorders. Хроническая послеоперационная боль – одна из актуальных медико-социальных проблем оперативной гинекологии, что обусловлено высоким уровнем распространенности, значительным влиянием на исходы хирургического лечения и, как следствие, качество жизни пациентов. Цель – изучение роли предоперационных нейромедиаторных и психоэмоциональных дисфункций в формировании хронического послеоперационного болевого синдрома в клинике оперативной гинекологии. Материалы и методы. В исследовании приняли участие 156 больных в возрасте от 18 до 45 лет, которым выполнено плановое хирургическое лечение по поводу гинекологической патологии. Пациенты в последующем были разделены на 2 группы: 1-я – женщины с хроническим послеоперационным болевым синдромом; 2-я – пациентки без хронического послеоперационного болевого синдрома. Наряду с общеклиническим обследованием c помощью иммуноферментного анализа определяли уровень кислоты и β-эндорфина в сыворотке крови. С целью оценки количественной характеристики боли применяли визуальную аналоговую шкалу, качественной – болевой опросник McGill, для оценки психоэмоционального статуса – клиническую шкалу HAM-A и HDRS. Результаты. Спустя 12 мес. после оперативного вмешательства хронический послеоперационный болевой синдром наблюдался у 39,7 % обследованных. В предоперационном периоде у всех обследованных отмечался болевой синдром, при этом достоверных межгрупповых различий его интенсивности не выявлено. В структуре болевого синдрома у пациенток 1-й группы выявлено статистически значимое преобладание показателей аффективной шкалы, у женщин 2-й группы – сенсорной (p=0,003). У пациенток 1-й группы изменения уровней ГАМК и β-эндорфина носили более выраженный характер. Установлена обратная корреляционная связь уровня β-эндорфина с показателями аффективной и эвалюативной шкал опросника McGill. Аффективная патология различной степени выраженности верифицирована у всех больных 1-й группы. В структуре преобладали депрессивные нарушения. У пациенток 2-й группы наблюдались лишь субдепрессивные состояния и отдельные, клинически не оформленные симптомы тревоги. Установлены корреляции депрессивных расстройств c выраженностью предоперационного болевого синдрома по визуально-аналоговой шкале, аффективной шкалой опросника McGill, концентрацией β-эндорфина. Выводы. Нейромедиаторные и психологические дисфункции влияют на формирование послеоперационного хронического болевого синдрома. Установлена связь между хроническим послеоперационным болевым синдромом и предоперационными значениями концентрации β-эндорфина (r=-0,70; p=0,028), выраженностью депрессивных расстройств (r=0,65; p=0,012), что подтверждает их роль как неспецифических прогностических маркеров при мониторинге формирования послеоперационного хронического болевого синдрома. Ключевые слова: гинекологическая патология, хронический послеоперационный болевой синдром, нейромедиаторы, аффективные расстройства.


2017 ◽  
Vol 41 (S1) ◽  
pp. S285-S285
Author(s):  
I. Makhortova ◽  
O. Shiryaev

Eating disorders of bulimic type are among the most common comorbidities with depression. The objective is to evaluate cognitive function and mood dynamics in patients with depression and eating disorders in pharmacotherapy. In total, 52 outpatients, who met criteria for “major depressive episode” (ICD-10), participated. The level of depression was estimated with Hamilton Depression rating scale (HAM-D) and cognitive function–Montreal Cognitive Assessment (MoCa). Sample was divided into two groups. Patients of group 1 also met criteria for eating disorder of bulimic type and patients of group 2 did not have any eating disorder. Treatment included standard doses of SSRI. Assessments were performed after 2, 4 and 8 weeks (D14, D30, D60). The level of HAM-D was significantly greater (P < 0.05) in eating disorders group (16.75 ± 2.83 in group 1; 13.04 ± 1.93 in group 2 at screening) and significance was preserved till D60 (9.39 ± 2.54 in group 1; 6.32 ± 1.27 in group 2 at D60). Clinically significant antidepressive effect was revealed faster in group 2 (at D7) compared to group 1 (at D14). Overall score of MoCA was significantly lower (P < 0.05) in eating disorders group (20.33 ± 0.54 in group 1; 23.43 ± 2.32 in group 2 at screening) at all stages of treatment (23.39 ± 0.78 in group 1; 26.96 ± 3.27 in group 2 at D60) and it reached normal range (25 and more) only in group 2 at D60. Significant change from screening was revealed at D30 at group 2 and at D60 at group 1.ConclusionEating disorder have an impact on SSRI treatment efficacy including antidepressive and procognitive effects. It is necessary to reveal eating disorders as a co-morbidity in patients with depression.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Pawel Matusik ◽  
Aneta Gawlik ◽  
Aleksandra Januszek-Trzciakowska ◽  
Ewa Malecka-Tendera

Objective. The study aim was to analyze whether anthropometrical parameters and TSH values in obese children with isolated subclinical hypothyroidism (IsHT) treated with levothyroxine (LT4) and weight reduction program differ from those managed by dietary and behavior counselling only.Material and Methods. 51 obese children with IsHT, who were treated according to the same weight reduction program, were retrospectively analyzed. They were divided into two groups: Group 1,n=26, and Group 2,n=25, without or with LT4 therapy, respectively. Changes in anthropometrical (delta BMIz-score) and hormonal (delta TSH) status were analyzed at the first follow-up visit.Results. In both groups significant decrease of TSH and BMIz-score values were noted. TSH normalized in 80.9% of children from Group 1 versus 90.5% from Group 2,p= NS. Delta BMIz-score was insignificantly higher in Group 1 compared to Group 2. Delta TSH was significantly related to initial TSH level in children treated by lifestyle intervention program only.Conclusions. In obese children with sHT dietary-behavioral management intervention contributed to reduction of body mass index, irrespective of levothyroxine use. This finding suggests that moderately elevated levels of TSH are a consequence rather than cause of overweight and pharmacological treatment should be avoided.


2006 ◽  
pp. 044-049
Author(s):  
Roza Viktorovna Enaldieva ◽  
Aleksandr Georgyevich Avtandilov ◽  
Stepan Timofeyevich Vetrile ◽  
Aleksandr Alekseyevich Kuleshov ◽  
I. V. Galichenko ◽  
...  

Objective. Complex estimation of pulmonary and systemic circulation in patients with various degree of scoliotic disease severity and duration. Material and Methods.We observed 210 patients at the age of 14 to 38 years with I–IV grade scoliosis. Sex ratio (male/female) was 1:6. All patients were divided in two groups according to the age: Group 1 – patients of 14–18 years old, with the average disease duration being 8.3 ± 3.6 year; Group 2 – 19–38 years old, with the average disease duration – 24.6 ± 1.9 years. Control group cosisted of 60 individuals without scoliotic deformities, heart and pulmonary diseases, and was comparable in age and sex. All groups underwent complex examination including standard Dopplerechocardiography. Results. Echocardiography demonstrated changes in systolic function of the left ventricle in patients with scoliosis which is naturally accompanied by central hemodynamics impairment. Hyperkinetic type of hemodynamics was revealed in patients with mild scoliosis and hypokinetic type – in patients with severe one. The study revealed pulmonary hypertension, rise of average blood pressure, increase in peripheral and lung vascular resistance in adolescents with clinically apparent scoliotic deformities. Impairment of central hemodynamics and pulmonary blood flow in adult patients with severe scoliosis were less pronounced. Conclusion. Impairment of systemic and pulmonary circulation has been revealed in patients with thoracic scoliosis, which is more pronounced in adolescents with severe and rapidly progressing forms of the disease. They suffer from early derangement of adaptation mechanism and progressing decrease in stroke and minute cardiac output, in spite of increase in cardiac beat rate; decrease in average hemodynamic pressure and rise of resistance in lesser and greater circulation.


2016 ◽  
Vol 33 (S1) ◽  
pp. S205-S206
Author(s):  
K. Cabas-Hoyos ◽  
J.L. Muñoz-Salgado ◽  
I. Cadavid-Perez ◽  
L. De Hoyos ◽  
G. Gonzalez-Gamero ◽  
...  

Catastrophism is a variable of great importance in the study of pain. Catastrophism refers to a negative and exaggerated compared to the experience of pain, both real and anticipated mental perception (Sullivan, Bishop and Pivik, 1995; Sullivan et al., 2001). The current study to compare the levels of catastrophism in patients with and without fibromialgia. This study is cross-cutting and comparative. Twenty participants (M: 47.20; SD: 12.11) distributed as the following way:– group 1: patients with fibromyalgia previously diagnosed through the American College of Rheumatology criteria (n = 10);– group 2: Clinical depression, defined according to the DSM-5 (n = 5);– group 3: healthy patients (n = 5) paired by age with the group of Fibromyalgia.The PCS, a self-administered, was used to measure Catastrophism. Responses were summed to yield three different subscales: Rumination, Magnification and Helplessness. This instrument is validated in both experimental and clinical population (Van Damme, Crombez, Bijttebier, Gouber and Van Houdenhove, 2002; Edwards et al., 2006). A comparison among the three groups was established using one-way factor ANOVA. The results point out that patients with fibromyalgia have higher levels of magnification controls with depression and healthy group (P < 0.05). In contrast, although the average level of Catastrophism total presented a greater tendency in fibromyalgia patients no statistically significant differences were found. This is discussed in relation to the literature, a higher level of magnification to explain pain and maintaining the chronicity of the disease. It is important to consider the component catastrophism to have a multidimensional view of pain.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2017 ◽  
Vol 41 (S1) ◽  
pp. S532-S532
Author(s):  
S. Lukmonov ◽  
N. Yadgarova

ObjectiveTo study the clinical - psychopathological characteristics of patients with resistant depression.Materials and methodsWe examined 96 patients aged 18–48 years (mean age 34.7 0 ± 1.0 years). The investigated patients were divided into two groups: 1st -TRD with positive affectivity - 59 (61.4%); 2nd - curable depression - 37 (38.6 %). Selection of patients was made according to following criteria: ICD - 10: (F31) - bipolar disorder; (F32) - depressive episode; (F33) - recurrent depressive disorder.ResultsIn group 1 patients received amitriptyline (TCA) - 50 mg - 2 times/day in one of 2 consecutive courses (within 6 weeks) and they showed no clinical benefit. In group 2 patients received amitriptyline - 50 mg 2 times/day for 2 consecutive courses. When analyzing the number of depressive episodes the statistically greater number was observed 1-3 episodes in group 2 - in 45.9% of patients than in group 1 - 16.9%, predominant 5-8 episodes - in 44.1% of patients in group 1, than in group 2 - 13.5%. Remissions, observed in group 2, were characterized by longer duration and have a higher quality than in patients of group 1. There is a tendency to shorten remission especially in group 1.ConclusionThe highest correlation dependence showed such factors as: frequency of depressive episodes, duration of episode 1, severity of depressive episode 1, quality of remission after depressive episode 1, number of responders at early stages of antidepressant therapy of I-st attack.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2017 ◽  
Vol 41 (S1) ◽  
pp. S455-S455
Author(s):  
P.T. ◽  
E. Mykhailova ◽  
T. Matkovska ◽  
N. Reshetovska ◽  
A. Goloborodko

Background and aimsThe study considers the problem of the anxiety-depressive disorders (ADD) in children with concomitant obesity in the context of the search for effective methods of their correction.Materials and methodsIncluded 64 children at puberty with the anxiety-depressive disorders, comorbid with obesity. Design comprised: clinicopsychopathological, somatoneurological, psychological monitoring (CDRS-R); the Spielberger, “Me and my illness” and “Man in the Rain” projective drawing tests.ResultsThe symptoms of emotional and vegetative tension, depression registered in all studied children.In the developed model of support, the interventions of primary level are aimed on family and closest encirclement of the child (family psychotherapy, psycho-educational programs for children and their parents). Strategies:– stressful situation in the family (practical, psychological support and education of parents);– for relief of depressive and vegetative-anxious symptoms (using art therapy, cognitive behavioral therapy);– for education of patients in the wider context – quality of life, coping, motivation and modification of inappropriate behaviors (modeling of new cognitions).The technology includes the diagnosis of the psychosomatic core of the disease, areas of neurotic fixation of the child with ADD and obesity, correction of emotional homeostasis and cognitive imbalance by activation of the personality individual resources as a result using cognitive-behavioral and art-dynamic therapy, as well as a “Control of eating behavior” training program, and solving certain situational problems by a child with the disease.ConclusionOur method makes the tactics of psychotherapeutic and psycho-educational intervention at an early stage of the disease.Disclosure of interestThe authors have not supplied their declaration of competing interest.


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