Development of phospholipid nanoparticles encapsulating 3-O-cetyl ascorbic acid and tocopherol acetate (TA-Cassome) for improving their skin accumulation

2018 ◽  
Vol 548 (1) ◽  
pp. 192-205 ◽  
Author(s):  
Tomoka Fushimi ◽  
Tomonobu Uchino ◽  
Yasunori Miyazaki ◽  
Ichiro Hatta ◽  
Miyuki Asano ◽  
...  
2016 ◽  
Vol 18 (3(70)) ◽  
pp. 200-204 ◽  
Author(s):  
L.V. Romanovich ◽  
B.M. Kurtyak ◽  
М.S. Romanovich ◽  
D.I. Mudrak

The article presents research data on indices of lipid peroxidation (TBA–active products and hydroperoxides lipids) in the blood of broiler chickens on the background of vaccination and disease Nyukasla for the actions of vitamins E and C.The study was conducted on three groups of 100 broiler birds each. Control group fed normal chicken feed. The first research group in addition to poultry feed said received – tocopherol acetate in an amount of 0.1 g/kg feed, the second – ascorbic acid 0.25 g/kg feed. The third research group chickens – tocopherol acetate and ascorbic acid at these doses. For research use blood that was in the chicken after decapitation at different ages: 11–, 27–, 34– and 41–day age. The results of performance of different age groups broiler chickens compared with the value of the index poultry 11–day age for vaccination, and a control group of birds.Studies have shown that the content of intermediate and final products of lipid peroxidation in the blood plasma of broilers depends on the age and period of immunization. Feeding high amounts of vitamin E and C in the composition of feed for broiler chickens caused a reduction (p < 0.05 – 0.001) content in plasma lipid hydroperoxides and TBA–active products. PAUL likely lower rates of broiler chickens research groups suggest reducing the negative impact of stress factors on their bodies on the background of vaccination against the disease Nyukasla. These changes were more pronounced in the blood of chickens, which in addition to the basic diet receiving tocopherol acetate and ascorbic acid. 


2020 ◽  
Vol 22 (97) ◽  
pp. 141-146
Author(s):  
L. V. Romanovych

Protein content and the ratio of its fractions were investigated in the serum of broiler chickens during the growing period with the addition of vitamins E and C to their ration. The investigations were performed in one of the farms in Lviv region on four groups of 100 broiler chickens in each, starting from 1- to 41-day-olds. Chickens in the control group received a standard ration, the first experimental diet with tocopherol acetate, the second experimental – ascorbic acid, and the third – a complex of these vitamins. Poultry research were conducted at different ages: 27-, 34-, and 41-day-olds. The content of common protein was determined in blood serum – biuret method and the range of soluble proteins – by vertical electrophoresis in plates of 7.5 % polyacrylamide gel. Conducted research have shown that the use of tocopherol acetate and ascorbic acid supplements to compound feed of broiler chickens caused a rise in serum total protein content. However, these changes were more pronounced in chickens with the combined use of vitamins E and C in all search periods (P < 0.05–0.01), and also in 11-day-old broilers (P < 0.05), who used ascorbic acid supplement. In the search of the ratio of protein fractions was ascertained an increase in the content of γ-globulin fraction in chickens from the search groups regarding controls at 11 and 27 days of age. Herewith the differences were likely to be in broiler chickens, who used the tocopherol acetate supplement. Instead, 11-day-old chicks in this group had a lower b-globulin fraction (P < 0.05). However, in the serum of chickens from the experimental groups regarding control at 41 days of age a significantly higher content of the α-globulin fraction was registered. In general, the results of the searches showed that additional introduction of tocopherol acetate and ascorbic acid to chickens ration has a stimulating influence on the processes of protein biosynthesis and immune function in the organism of chickens in the process of their growth. This influence was more expressed in chickens with the combined use of vitamins E and C.


2011 ◽  
Vol 82 (1) ◽  
pp. 247-252 ◽  
Author(s):  
Xiao-Mei Wu ◽  
Christopher J. Branford-White ◽  
Deng-Guang Yu ◽  
Nicholas P. Chatterton ◽  
Li-Min Zhu

2012 ◽  
Vol 48 (No. 1 - 2) ◽  
pp. 33-40 ◽  
Author(s):  
O. Kucuk ◽  
N. Sahin ◽  
K. Sahin ◽  
Gursu MF ◽  
F. Gulcu ◽  
...  

This experiment was conducted to evaluate the effects of vitamin C (L-ascorbic acid) and vitamin E (&alpha;-tocopherol acetate) on egg production, egg quality, lipid peroxidation status (measured as MDA), and some serum metabolites in laying hens (Hy-Line) maintained at a low ambient temperature (6&deg;C). One hundred and twenty laying hens (18-wk-old) were divided into four groups, 30 hens per group. The laying hens were fed either a basal diet or the basal diet supplemented with either 250 mg of L-ascorbic acid/kg of diet, 250 mg of &alpha;-tocopherol acetate/kg of diet or 250 mg of L-ascorbic acid plus 250 mg of &alpha;-tocopherol acetate/kg of diet. Although feed consumption of the hens was similar (P &gt; 0.05) among treatments, supplemental vitamin C and E significantly increased final body weight, egg production, and improved feed efficiency (P &lt; 0.05). Egg weights were also greater (P &lt; 0.05) in hens supplemented with the combination of vitamin C and E than that of hens supplemented either vitamin or no vitamin (control). Haugh unit did not change upon each vitamin supplementation, but the combination of the vitamin supplement yielded a higher Haugh unit (P &lt; 0.05). Each dietary supplement of vitamin C and vitamin E improved the egg quality (P &lt; 0.05) resulting in a greater specific gravity, thicker egg shell, and heavier egg shell weight. Separately or as a combination, supplemental vitamin C and E decreased MDA, glucose, cholesterol, and triglyceride concentrations (P &lt; 0.05). Results of the present study showed that supplementing vitamin C and vitamin E, particularly as a combination, improved the performance of cold-stressed laying hens, offering a potential protective management practice in preventing cold stress-related losses in performance of laying hens. Results of the present study also indicated that the effects of vitamin C and vitamin E are additive.


2016 ◽  
Vol 161 (2) ◽  
pp. 248-251 ◽  
Author(s):  
I. N. Vasil’eva ◽  
V. G. Bespalov ◽  
D. A. Baranenko

Author(s):  
O. I. Vishchur ◽  
L. V. Romanovych ◽  
K. B. Smolyaninov ◽  
M. B. Masyuk ◽  
М. М. Romanovych

The purpose of the work was to find out the changes in the lipid composition of the liver and skeletal muscles of broiler chickens at different stages of growth under the influence of supplements of vitamins E and C in their diet. The studies were conducted on four groups of broiler chickens. The control group was fed a standard compound feed. The first experimental group in addition to the specified compound feed received tocopherol acetate in the amount of 0.1 g/kg, the second — ascorbic acid, 0.25 g/kg. The third experimental group of chickens received tocopherol acetate and ascorbic acid at mentioned doses. The lipids from these tissues were extracted by the Folch method, and the ratio of individual lipid classes was determined by thin layer chromatography on silica gel. The results of the studies indicate the stimulating effect of vitamins E and C on the accumulation of total lipids in the skeletal muscles and liver of broiler chickens. In addition, we can conclude that feeding the broiler chickens of supplements containing vitamins E and C during the period of intensive growth promotes the increase of lipid synthesis in their liver and deposition of synthesized lipids in skeletal muscle. However, these processes are accompanied by a redistribution of the ratio of individual lipid classes in the investigated organs and tissues of chickens


2004 ◽  
Vol 97 (2) ◽  
pp. 149-162 ◽  
Author(s):  
Sadakat Ozdil ◽  
Sehnaz Bolkent ◽  
Refiye Yanardag ◽  
Pelin Arda-Pirincci

Sign in / Sign up

Export Citation Format

Share Document