Cardiorespiratory Fitness, Macronutrient Intake, and the Metabolic Syndrome: The Aerobics Center Longitudinal Study

2006 ◽  
Vol 106 (5) ◽  
pp. 673-679 ◽  
Author(s):  
Carrie E. Finley ◽  
Michael J. LaMonte ◽  
Carol I. Waslien ◽  
Carolyn E. Barlow ◽  
Steven N. Blair ◽  
...  
2015 ◽  
Vol 12 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Anna E. Greer ◽  
Xuemei Sui ◽  
Andréa L. Maslow ◽  
Beau Kjerulf Greer ◽  
Steven N. Blair

Background:To date, no longitudinal studies have examined the influence of sedentary behavior on metabolic syndrome development while accounting for cardiorespiratory fitness.Purpose and Methods:This prospective study examined the relationship between sedentary behavior and incident metabolic syndrome while considering the effects of physical activity and cardiorespiratory fitness on the association among 930 men enrolled in the Aerobics Center Longitudinal Study.Results:A total of 124 men developed metabolic syndrome during 8974 person-years of exposure. After adjusting for covariates, men with middle and high sedentary behavior had 65% and 76% higher risks of developing metabolic syndrome, respectively, than men with low sedentary behavior (linear trend P = .011). This association remained significant after additional adjustment for activity status and cardiorespiratory fitness. Cardiorespiratory fitness and physical activity were also inversely associated with metabolic syndrome, even after adjustment for sedentary behavior.Conclusions:The findings highlight the importance of reducing sedentary behavior, increasing physical activity, and improving cardiorespiratory fitness for preventing metabolic syndrome.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lars Lind ◽  
Johan Sundström ◽  
Johan Ärnlöv ◽  
Ulf Risérus ◽  
Erik Lampa

AbstractThe impact of most, but not all, cardiovascular risk factors decline by age. We investigated how the metabolic syndrome (MetS) was related to cardiovascular disease (CVD) during 40 years follow-up in the Uppsala Longitudinal Study of Adult Men (ULSAM, 2,123 men all aged 50 at baseline with reinvestigations at age 60, 70, 77 and 82). The strength of MetS as a risk factor of incident combined end-point of three outcomes (CVD) declined with ageing, as well as for myocardial infarction, ischemic stroke and heart failure when analysed separately. For CVD, the risk ratio declined from 2.77 (95% CI 1.90–4.05) at age 50 to 1.30 (95% CI 1.05–1.60) at age 82. In conclusion, the strength of MetS as a risk factor of incident CVD declined with age. Since MetS was significantly related to incident CVD also at old age, our findings suggest that the occurrence of MetS in the elderly should not be regarded as innocent. However, since our data were derived in an observational study, any impact of MetS in the elderly needs to be verified in a randomized clinical intervention trial.


PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0131586 ◽  
Author(s):  
Örjan Ekblom ◽  
Elin Ekblom-Bak ◽  
Annika Rosengren ◽  
Mattias Hallsten ◽  
Göran Bergström ◽  
...  

2019 ◽  
Vol 16 (11) ◽  
pp. 968-975
Author(s):  
Leanna M. Ross ◽  
Jacob L. Barber ◽  
Alexander C. McLain ◽  
R. Glenn Weaver ◽  
Xuemei Sui ◽  
...  

Background: This study examined the cross-sectional and longitudinal associations of cardiorespiratory fitness (CRF) and ideal cardiovascular health (CVH). Methods: CRF and the 7 CVH components were measured in 11,590 (8865 males; 2725 females) adults at baseline and in 2532 (2160 males; 372 females) adults with at least one follow-up examination from the Aerobics Center Longitudinal Study. Ideal CVH score was calculated as a composite of 7 measures, each scored 0 to 2. CVH groups were based on participant point score: ≤7 (poor), 8 to 11 (intermediate), and 12 to 14 (ideal). Analyses included general linear, logistic regression, and linear mixed models. Results: At baseline, participants in the high CRF category had 21% and 45% higher mean CVH scores than those in the moderate and poor CRF categories (P < .001). The adjusted odds (95% confidence interval) of being in the poor CVH group at baseline were 4.9 (4.4–5.4) and 16.9 (14.3–19.9) times greater for individuals with moderate and low CRF, respectively, compared with those with high CRF (P < .001). Longitudinal analysis found that for every 1-minute increase in treadmill time, CVH score increased by 0.23 units (P < .001) independent of age, sex, exam number, and exam year. Conclusions: Higher CRF is associated with better CVH profiles, and improving CRF over time is independently associated with greater improvements in CVH.


2011 ◽  
Vol 35 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Wonwoo Byun ◽  
Xuemei Sui ◽  
James R. Hébert ◽  
Timothy S. Church ◽  
I-Min Lee ◽  
...  

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