Site-specific halloysite functionalization by polydopamine: A new synthetic route for potential near infrared-activated delivery system

2022 ◽  
Vol 606 ◽  
pp. 1779-1791
Author(s):  
Maria Laura Alfieri ◽  
Marina Massaro ◽  
Marco d'Ischia ◽  
Gerardino D'Errico ◽  
Noemi Gallucci ◽  
...  
Keyword(s):  
Delivery System ◽  
Near Infrared ◽  
Synthetic Route ◽  
Site Specific

scholarly journals Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy

2018 ◽  
Vol 115 (3) ◽  
pp. 501-506 ◽  
Author(s):  
Meng Qiu ◽  
Dou Wang ◽  
Weiyuan Liang ◽  
Liping Liu ◽  
Yin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Deep Penetration ◽  
Nir Light

A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.

Dendrimer-modified gold nanorods as efficient controlled gene delivery system under near-infrared light irradiation

2011 ◽  
Vol 152 ◽  
pp. e137-e139 ◽  
Author(s):  
Daxiang Cui ◽  
Peng Huang ◽  
Chunlei Zhang ◽  
Cengiz S. Ozkan ◽  
Bifeng Pan ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Delivery System ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Light Irradiation ◽  
Infrared Light ◽  
Gene Delivery System ◽  
Near Infrared Light

A multifunctional near-infrared laser-triggered drug delivery system using folic acid conjugated chitosan oligosaccharide encapsulated gold nanorods for targeted chemo-photothermal therapy

2019 ◽  
Vol 7 (24) ◽  
pp. 3811-3825 ◽  
Author(s):  
Panchanathan Manivasagan ◽  
Seung Won Jun ◽  
Van Tu Nguyen ◽  
Nguyen Thanh Phong Truong ◽  
Giang Hoang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Folic Acid ◽  
Combination Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Laser ◽  
Chitosan Oligosaccharide

FA–COS–TGA–GNRs–DOX have been successfully designed as a drug delivery system for chemo-photothermal combination therapy.

scholarly journals PORPHYSOMES-A PARADIGM SHIFT IN TARGETED DRUG DELIVERY

2018 ◽  
Vol 10 (2) ◽  
pp. 1 ◽  
Author(s):  
Revathy B. Menon ◽  
Lakshmi V. S. ◽  
Aiswarya M. U. ◽  
Keerthana Raju ◽  
Sreeja C. Nair
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Near Infrared ◽  
Delivery Systems ◽  
Optimum Dose ◽  
Advantages And Disadvantages ◽  
The Right ◽  
Aqueous Core

A novel drug delivery system is the one that ensures optimum dose at the right time, at the right location. Porphysomes are among those drug delivery systems. Porphysomes are a means of vesicular drug delivery systems. They are liposome-like structures composed completely of porphyrin lipid. The porphysomes encapsulates the active medicament in vesicular structure. They are having an aqueous core which can be loaded with the medicament. They have the capacity to destroy the disease tissues. They absorb the heat in the near infrared region and release this heat to destroy the diseased tissues. Porphysomes are having immense applications in the field of positron-electron therapy (PET), photoacoustic imaging, photothermal therapy etc. This review article discusses regarding the Porphysome-the drug delivery system, its advantages and disadvantages, composition, method of preparation, applications and various aspects related to the porphysomal drug delivery.

scholarly journals Polymer microchamber arrays for geometry-controlled drug release: a functional study in human cells of neuronal phenotype

2019 ◽  
Vol 7 (6) ◽  
pp. 2358-2371 ◽  
Author(s):  
Olga Kopach ◽  
Kayiu Zheng ◽  
Olga A. Sindeeva ◽  
Meiyu Gai ◽  
Gleb B. Sukhorukov ◽  
...  
Keyword(s):  
Drug Release ◽  
Delivery System ◽  
Controlled Drug Release ◽  
Functional Study ◽  
Specific Drug ◽  
Polyelectrolyte Multilayer ◽  
Site Specific ◽  
Neuronal Phenotype ◽  
On Demand ◽  
Cargo Delivery

Polyelectrolyte multilayer (PEM) microchambers can provide a versatile cargo delivery system enabling rapid, site-specific drug release on demand.

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