Eyelid fungal infections are rare, and often associated with predisposing factors. We present the case of a child with an ulcerated lesion of fungal etiology on the eyelid.

2017 ◽  
Vol 52 (1) ◽  
pp. e28-e29
Author(s):  
Roshmi Gupta ◽  
Parvathi Hari ◽  
Venkataramana Anandula
Author(s):  
Dhanapal Nandini ◽  
J. Manonmoney ◽  
J. Lavanya ◽  
K.V. Leela ◽  
Sujith

Candida spp. is one among the major causes of nosocomial infection, with candidemia gaining increasing prevalence worldwide in parallel with mortality rates ranging from 10-49%. Epidemiology and predisposing factors of candidemia have changed since the number of patients receiving transplants and immunosuppressive therapy, the use of broadspectrum antimicrobials, and the number of AIDS patients have increased. Candidemia is more common among patients with subcutaneous and cutaneous candida infections, through percutaneous inoculation. Major predisposing factors for invasive candidiasis includes neutropenia, haematological malignancies, bone marrow transplantation, total parenteral nutrition, chemotherapy, invasive procedures, and immune-suppressive agents. This study analyses the risk factors of immunocompromised patients with candidemia and antibiogram of Candida spp. isolated from ICU patients. To evaluate the prevalence, distribution and antibiogram of Candida spp., associated risk factors, and outcome in candidemia patients. Blood samples received from patients with clinically suspected fungal infections were subjected to gram staining, culture, sugar assimilation & fermentation, Candida Chrome agar (CCA) & Corn meal agar for identification and speciation. Antifungal susceptibility tests were performed by disk-diffusion tests. Among a total of 337 samples received, 22 (6.5%) samples were positive for candida infections, of which Candida tropicalis 9 (41%) was the predominant isolate followed by C. albicans 5 (23%), Candida glabrata 4 (18%), Candida parapsilosis 2 (9%) and Candida krusei 2 (9%). Male patients had a higher prevalence of candidemia 15 (68.2%). Among the age group of 51-70 years, uncontrolled DM(Diabetes mellitus) and CKD (chronic kidney disease) were found to be the predominant co-morbidities with candidemia.


2021 ◽  
pp. 70-72
Author(s):  
Indira Ananthapadmanab asamy ◽  
G. Rajaram ◽  
CH. Srinivasa Rao

Purpose: SARS CoV 2 virus a novel coronavirus, which is a single stranded positive sense RNA virus. It causes severe pneumonia in susceptible individuals. In individuals with predisposing factors, like diabetes, neutropenia, corticosteroids therapy, and etc., the virus causes opportunistic fungal infections. This study aims the correlation between COVID 19 disease and fungal infections. Methodology: The present study includes 202 specimens collected from patients with symptoms suspected of fungal infections. The collected specimens were subjected to direct microscopy and fungal culture. Results: Nasal tissue scrapings were the most common specimen collected followed by sputum. Among the 202 specimens collected, 106 were positive for direct microscopy and 81 were positive for fungal culture. Conclusion: The fungal infections are more common among the patients with comorbidities, and appropriate guidelines should be followed in the management of such infections in order to prevent the morbidity and the mortality.


1995 ◽  
Vol 154 (1) ◽  
pp. 160-163 ◽  
Author(s):  
Mark A. Wainstein ◽  
Richard C. Graham ◽  
Martin I. Resnick

Author(s):  
Amin Gharanfoli ◽  
Elaheh Mahmoudi ◽  
Roya Torabizadeh ◽  
Roya Torabizadeh ◽  
Farzad Katiraii ◽  
...  

Short communication Background and Purpose: Candida species are reportedly the most common human fungal pathogens. The incidence of urinary tract infections (UTIs) caused by Candida pathogens has increased in recent decades. However, such infections rarely occur in the absence of any predisposing factors. Regarding this, the aim of the present study was to identify the Candida species causing UTIs and determine the predisposing factors for candiduria. Materials and Methods: The current study was conducted on 1,450 urine samples obtained from patients suspected of UTI. Out of this number, 19 cases were candidiasis, and 2 cases were mixed infections caused by bacteria and fungi. Candida species were diagnosed differentially using the germ tube test, colony staining on CHROMagar medium, intracellular beta-glucosidase enzyme activity, and glucose absorption pattern. Then, the colonies with the same morphology were confirmed by the DNA sequencing of internal transcribed spacer regions. Results: According to the results, 38%, 28.6%, 14.3%, and 9.5% of the isolates were identified as C. albicans, C. glabrata, C. tropicalis, and C. kefir/C. krusei, respectively. The presence of one or more predisposing factors was proved in all patients in whom diabetes was the most prevalent predisposing factor (21.1%). Conclusion: Based on the obtained results, C. albicans species was the most prevalent fungal species. In addition, urinary fungal infections were less prevalent than bacterial urinary infections.


2019 ◽  
Vol 9 (4-A) ◽  
pp. 355-357
Author(s):  
Bhawna Pant ◽  
Prashant Mathur ◽  
Yogesh Joshi

A corneal ulcer is a painful open sore on the cornea that can cause loss of vision and even blindness. The aim the study is to assess the prevalence, predisposing factors, etiology and treatment of corneal ulcer patients. 100 patients with corneal ulcer were included in the study. A detailed history with socio-demographic information, presenting complaints, predisposing factors, associated risk factors followed by drug therapy was noted carefully. Gender wise distribution showed that males (61%) were mostly affected by corneal ulcer as compared to females (39%). Occupation wise distribution showed that farmers (38%) were affected more as compared to others. Most commonly affected age group was between 41-60 years and majority of affected people were from rural areas (75%). Based on severity of the diseased condition, majority (39%) were diagnosed severe followed by mild (34%) to moderate (27%) among all corneal ulcer patients. The most common predisposing risk factor found for corneal ulcer was ocular trauma (42%). Bacterial infections (44%) were found more commonly than fungal infections (35%) and other causes. Antibiotics were mostly prescribed (44%) followed by traditional eye medicines (23%) and antifungal (16%) drugs. Such comprehensive studies are important to assess the specific epidemiological characteristics of corneal ulceration and are also necessary to define the magnitude of the problem in society, to design an efficient public health program for rapid referral, diagnosis, treatment, and to prevent corneal ulceration in the population at risk, especially in the developing nations.


1995 ◽  
pp. 160-163 ◽  
Author(s):  
Mark A. Wainstein ◽  
Richard C. Graham ◽  
Martin I. Resnick

2019 ◽  
Vol 3 (4) ◽  
pp. 182-186
Author(s):  
Sri Hernawati

Background: A geographic tongue is an inflammatory lesion of the tongue accompanied with atrophy formation of papilla or depapilation of the filiform papillae. The geographic tongue usually appears together with the appearance of the fissure tongue, a midline, multiple, fissure on the surface of the tongue that expands from front to back and has various patterns. Predisposing factors of geographic tongue and fissure tongue are nutritional deficiencies and stress. Oral candidiasis is one of the fungal infections that affect the oral mucosa caused by the fungus Candida albicans. Predisposing factors of oral candidiasis e.g. stress, and smoking habits. Case: 64-year-old male patient with a clinical appearance on the dorsum of the tongue in a bracelet-like form with depapilation, vertical fissure 3 mm deep and thick white plaque which could be scraped and felt painful. Diagnosis: geographic tongue, fissure tongue and oral candidiasis. Therapy: aloe vera in oral solution as antiinflammatory and analgesic, Nystatin oral suspension functions as a topical antifungal medicine, multivitamin Becomzet (Vitamin B complex, A, C, E, and Zinc) as a multivitamin. Conclusion: after therapy using aloe vera solution, nystantin becomzet controls both patients had undergone a healing process in both the case of geographic tongue, fissure tongue and oral candidiasis. Keywords: Geographic tongue, Candidasis


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