Cancer therapy based on extracellular vesicles as drug delivery vehicles

2020 ◽  
Vol 327 ◽  
pp. 296-315 ◽  
Author(s):  
Laura Cabeza ◽  
Gloria Perazzoli ◽  
Mercedes Peña ◽  
Ana Cepero ◽  
Cristina Luque ◽  
...  
2021 ◽  
Vol 2 (4) ◽  
pp. 795-816
Author(s):  
Md Salman Shakil ◽  
Kazi Mustafa Mahmud ◽  
Mohammad Sayem ◽  
Mahruba Sultana Niloy ◽  
Sajal Kumar Halder ◽  
...  

Cancer is one of the major causes of death worldwide. Chemotherapeutic drugs have become a popular choice as anticancer agents. Despite the therapeutic benefits of chemotherapeutic drugs, patients often experience side effects and drug resistance. Biopolymers could be used to overcome some of the limitations of chemotherapeutic drugs, as well as be used either as anticancer agents or drug delivery vehicles. Chitosan is a biocompatible polymer derived from chitin. Chitosan, chitosan derivatives, or chitosan nanoparticles have shown their promise as an anticancer agent. Additionally, functionally modified chitosan can be used to deliver nucleic acids, chemotherapeutic drugs, and anticancer agents. More importantly, chitosan-based drug delivery systems improved the efficacy, potency, cytotoxicity, or biocompatibility of these anticancer agents. In this review, we will investigate the properties of chitosan and chemically tuned chitosan derivatives, and their application in cancer therapy.


2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Gensheng Zhang ◽  
Xiaofang Huang ◽  
Huiqing Xiu ◽  
Yan Sun ◽  
Jiming Chen ◽  
...  

2011 ◽  
Vol 8 (5) ◽  
pp. 1669-1676 ◽  
Author(s):  
Qimeng Quan ◽  
Jin Xie ◽  
Haokao Gao ◽  
Min Yang ◽  
Fan Zhang ◽  
...  

2019 ◽  
Vol 36 (12) ◽  
Author(s):  
Xiaoyin Qiao ◽  
Yikun Yang ◽  
Ruiying Huang ◽  
Xuelei Shi ◽  
Haoxiang Chen ◽  
...  

2016 ◽  
Vol 11 (4) ◽  
pp. 329-342 ◽  
Author(s):  
Il-Kwon Kim ◽  
Sun-Hyun Kim ◽  
Seong-Mi Choi ◽  
Byung-Soo Youn ◽  
Han-Soo Kim

2018 ◽  
Vol 128 ◽  
pp. S18 ◽  
Author(s):  
Matthew J. Haney ◽  
Natalia L. Klyachko ◽  
Yuling Zhao ◽  
Alexander V. Kabanov ◽  
Elena V. Batrakova

2015 ◽  
Vol 3 (46) ◽  
pp. 9033-9042 ◽  
Author(s):  
Mengni He ◽  
Jiajia Zhou ◽  
Jian Chen ◽  
Fangcai Zheng ◽  
Dongdong Wang ◽  
...  

Controlled drug release is a promising approach for cancer therapy due to its merits of reduced systemic toxicity and enhanced antitumor efficacy.


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