The relationship of diabetes-related distress and depressive symptoms with physical activity and dietary behaviors in adults with type 2 diabetes: A cross-sectional study

Background: Studies in different populations have shown an association between diabetes mellitus and G6PD deficiency. This association has not been investigated in the Ghanaian population. We conducted a cross-sectional study to investigate the relationship between G6PD deficiency and type 2 diabetes mellitus in a Ghanaian population.Methods: The cross-sectional study involved 125 registered type 2 diabetes mellitus clients and 125 non-diabetic individuals. Chi-square analysis was used to assess the association between G6PD status and type 2 diabetes mellitus with statistical significance pegged at p-value<0.05.Results: The prevalence of G6PD deficiency in the study population was 24.0% and 13.6% for the diabetics and non-diabetics respectively. In terms of gender, 29.5% of the diabetic males were G6PD deficient whiles G6PD deficiency was observed in 11.1% of the non-diabetic males. Additionally, 21.0% of the diabetic females were also G6PD deficient with 15.3% of the non-diabetic females being G6PD deficient. The results showed that the overall G6PD deficiency was significantly associated with type 2 diabetes mellitus as compared to the non-diabetics. In terms of gender differences, G6PD deficiency was significantly associated with type 2 diabetes in males but, there was no significant association in females.Conclusions: The study reports the first findings of the relationship between G6PD deficiencies among type 2 diabetes patients in Ghana. The study revealed that G6PD deficiency is more prevalent among type 2 diabetics than non-diabetics. Type 2 diabetes mellitus is independently associated with G6PD deficiency in males but not females.

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Impact of physical activity and sedentary time on glycated hemoglobin levels and body composition: Cross‐sectional study using outpatient clinical data of Japanese patients with type 2 diabetes

Journal of Diabetes Investigation ◽

10.1111/jdi.13185 ◽

2019 ◽

Vol 11 (3) ◽

pp. 633-639 ◽

Cited By ~ 1

Author(s):

Shuhei Nakanishi ◽

Hidenori Hirukawa ◽

Masashi Shimoda ◽

Fuminori Tatsumi ◽

Kenji Kohara ◽

...

Keyword(s):

Physical Activity ◽

Type 2 Diabetes ◽

Body Composition ◽

Sedentary Time ◽

Glycated Hemoglobin ◽

Japanese Patients ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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A Pilot Study on the Effect of Anti-Thrombopoietin Antibody on Platelet Count in Patients with Type 2 Diabetes

Molecules ◽

10.3390/molecules25071667 ◽

2020 ◽

Vol 25 (7) ◽

pp. 1667

Author(s):

Takuya Fukuda ◽

Masahide Hamaguchi ◽

Takafumi Osaka ◽

Yoshitaka Hashimoto ◽

Emi Ushigome ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Platelet Count ◽

Cross Sectional Study ◽

Regression Analyses ◽

Sectional Study ◽

Cross Sectional ◽

Platelet Production ◽

The Relationship

Thrombopoietin (THPO) is a circulatory cytokine that plays an important role in platelet production. The presence of anti-THPO antibody relates to thrombocytopenia and is rarely seen in hematopoietic and autoimmune diseases. To date, there had been no reports that focused on the anti-THPO antibody in patients with type 2 diabetes mellitus (T2DM). To evaluate prevalence of the anti-THPO antibody in patients with T2DM and the relationship between anti-THPO antibody and platelet count, a cross-sectional study was performed on 82 patients with T2DM. The anti-THPO antibody was measured by ELISA using preserved sera and detected in 13 patients. The average platelet count was significantly lower in patients with the anti-THPO antibody than in those without the anti-THPO antibody. Multivariate linear regression analyses showed a significant relationship between the anti-THPO antibody and platelet count, after adjusting for other variables. To our best knowledge, this was the first report on the effect of the anti-THPO antibody on platelet count in patients with T2DM. Further investigation is needed to validate the prevalence and pathological significance of the anti-THPO antibody in patients with T2DM.

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Low Levels of Usual Physical Activity Are Associated with Higher 24 h Blood Pressure in Type 2 Diabetes Mellitus in a Cross-Sectional Study

Journal of Diabetes Research ◽

10.1155/2017/6232674 ◽

2017 ◽

Vol 2017 ◽

pp. 1-8 ◽

Cited By ~ 1

Author(s):

Alessandra Teixeira Neto Zucatti ◽

Tatiana Pedroso de Paula ◽

Luciana Verçoza Viana ◽

Rafael DallAgnol ◽

Felipe Vogt Cureau ◽

...

Keyword(s):

Physical Activity ◽

Diabetes Mellitus ◽

Blood Pressure ◽

Type 2 Diabetes ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Type 2 Dm ◽

Low Levels

The aim of this study is to evaluate the association between usual physical activity and 24 h blood pressure (BP) profile in people with type 2 diabetes mellitus (DM). This is a cross-sectional study of 151 participants with type 2 DM. Usual physical activity was assessed by step counting and self-reported questionnaire. BP was measured in office and by 24 h ambulatory BP monitoring (ABPM; 24 h, daytime and nighttime). Mean participant age was 61.1 ± 8.4 years, 64% was women, and mean duration of diabetes was 14.3 ± 8.5 years. Ninety-two percent of participants had hypertension, and office BP was 138 ± 18/78 ± 10 mmHg. Inverse correlations were observed between step count and 24 h BP (systolic, r=−0.186; p=0.022), daytime BP (systolic, r=−0.198; p=0.015), and nighttime BP (pulse pressure, r=−0.190; p=0.019). People were categorized into tertiles of daily step count, and the 1st tertile had higher 24 h systolic BP, daytime systolic BP, daytime mean BP, and daytime systolic BP load than those in the other tertiles, even after adjusting for age and HbA1c. Participants with type 2 DM and low levels of physical activity exhibit higher 24 h and daytime systolic ambulatory BP values as compared with those who performed more steps per day, even after adjustments for confounding factors.

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