Atmospheric plasma-based approaches for the degradation of dimethyl phthalate (DMP) in water

Background: Application of cold atmospheric plasma to medium generates “plasma-activated medium” that induces apoptosis selectively in tumor cells and that has an antitumor effect in vivo. The underlying mechanisms are not well understood. Objective: Elucidation of potential chemical interactions within plasma-activated medium and of reactions of medium components with specific target structures of tumor cells should allow to define the active principle in plasma activated medium. Methods: Established knowledge of intercellular apoptosis-inducing reactive oxygen/nitrogen species-dependent signaling and its control by membrane-associated catalase and SOD was reviewed. Model experiments using extracellular singlet oxygen were analyzed with respect to catalase inactivation and their relevance for the antitumor action of cold atmospheric plasma. Potential interactions of this tumor cell-specific control system with components of plasma-activated medium or its reaction products were discussed within the scope of the reviewed signaling principles. Results: None of the long-lived species found in plasma-activated medium, such as nitrite and H2O2, nor OCl- or .NO seemed to have the potential to interfere with catalase-dependent control of apoptosis-inducing signaling of tumor cells when acting alone. However, the combination of H2O2 and nitrite might generate peroxynitrite. The protonation of peroxnitrite to peroxynitrous acid allows for the generation of hydroxyl radicals that react with H2O2, leading to the formation of hydroperoxide radicals. These allow for singlet oxygen generation and inactivation of membrane-associated catalase through an autoamplificatory mechanism, followed by intercellular apoptosis-inducing signaling. Conclusion: Nitrite and H2O2 in plasma-activated medium establish singlet oxygen-dependent interference selectively with the control system of tumor cells.

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The Application of the Cold Atmospheric Plasma-Activated Solutions in Cancer Treatment

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520617666170731115233 ◽

2018 ◽

Vol 18 (6) ◽

pp. 769-775 ◽

Cited By ~ 13

Author(s):

Dayun Yan ◽

Jonathan H. Sherman ◽

Michael Keidar

Keyword(s):

Cancer Treatment ◽

Atmospheric Plasma ◽

Current Status ◽

Cold Atmospheric Plasma ◽

Anti Cancer ◽

Long Time ◽

Key Topics ◽

The Common

Background: Over the past five years, the cold atmospheric plasma-activated solutions (PAS) have shown their promissing application in cancer treatment. Similar as the common direct cold plasma treatment, PAS shows a selective anti-cancer capacity in vitro and in vivo. However, different from the direct cold atmospheric plasma (CAP) treatment, PAS can be stored for a long time and can be used without dependence on a CAP device. The research on PAS is gradually becoming a hot topic in plasma medicine. Objectives: In this review, we gave a concise but comprehensive summary on key topics about PAS including the development, current status, as well as the main conclusions about the anti-cancer mechanism achieved in past years. The approaches to make strong and stable PAS are also summarized.

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Atmospheric plasma-aided biocidal finishes for nonwoven polypropylene fabrics. II. Functionality of synthesized fabrics

Journal of Applied Polymer Science ◽

10.1002/app.24042 ◽

2006 ◽

Vol 103 (3) ◽

pp. 1911-1917 ◽

Cited By ~ 26

Author(s):

D. M. Wafa ◽

F. Breidt ◽

S. M. Gawish ◽

S. R. Matthews ◽

K. V. Donohue ◽

...

Keyword(s):

Atmospheric Plasma

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Activation of deionized water by atmospheric plasma jet in helium gas flow

10.1063/5.0037155 ◽

2021 ◽

Author(s):

P. Y. Tan ◽

O. H. Chin ◽

R. Anpalagan ◽

Y. T. Lau ◽

H. C. Lee

Keyword(s):

Gas Flow ◽

Plasma Jet ◽

Deionized Water ◽

Atmospheric Plasma ◽

Helium Gas

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A map of control for cold atmospheric plasma jets: From physical mechanisms to optimizations

Applied Physics Reviews ◽

10.1063/5.0022534 ◽

2021 ◽

Vol 8 (1) ◽

pp. 011306

Author(s):

Li Lin ◽

Michael Keidar

Keyword(s):

Plasma Jets ◽

Atmospheric Plasma ◽

Cold Atmospheric Plasma ◽

Physical Mechanisms

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The Whitening Effect and Histological Safety of Nonthermal Atmospheric Plasma Inducing Tooth Bleaching

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18094714 ◽

2021 ◽

Vol 18 (9) ◽

pp. 4714

Author(s):

Seoul-Hee Nam ◽

Byul Bo Ra Choi ◽

Gyoo-Cheon Kim

Keyword(s):

Alternative Energy ◽

Soft Tissues ◽

Inflammatory Responses ◽

Color Change ◽

Atmospheric Pressure Plasma ◽

Atmospheric Plasma ◽

Tooth Bleaching ◽

Histological Evaluation ◽

Light Sources ◽

Tooth Color

Various light sources have been applied to enhance the bleaching effect. This study was to identify the histological evaluation in oral soft tissues, as well as tooth color change after tooth bleaching by nonthermal atmospheric pressure plasma (NAPP). Nine New Zealand adult female rabbits were randomly divided into three groups (n = 3): group 1 received no treatment; group 2 was treated with NAPP and 15% carbamide peroxide (CP), which contains 5.4% H2O2, and group 3 was treated with 15% CP without NAPP. Color change (ΔE) was measured using the Shade Eye NCC colorimeter. Animals were euthanized one day later to analyze the histological responses occurring in oral soft tissues, including pulp, gingiva, tongue, buccal mucosa, and hard and soft palates. Changes in all samples were analyzed by hematoxylin and eosin staining and Masson’s trichrome. Teeth treated with plasma showed higher ΔE than that obtained with bleaching agents alone. Overall, the histological characteristics observed no appreciable changes. The combinational treatment of plasma had not indicated inflammatory responses as well as thermal damages. NAPP did not cause histological damage in oral soft tissues during tooth bleaching. We suggest that NAPP could be a novel alternative energy source to conventional light sources for tooth bleaching.

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