The impact of a nationwide effort to reduce airbag-related deaths among children: An examination of fatality trends among younger and older age groups

2005 ◽  
Vol 36 (4) ◽  
pp. 309-320 ◽  
Author(s):  
James L. Nichols ◽  
Donna Glassbrenner ◽  
Richard P. Compton
Keyword(s):  
Age Groups ◽  
Older Age ◽  
The Impact

scholarly journals Incidence, clinical features, and outcomes of COVID-19 in Canada: impact of sex and age

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Jacob O’Brien ◽  
Kevin Y. Du ◽  
Chun Peng
Keyword(s):  
Incidence Rate ◽  
Age Groups ◽  
Case Fatality ◽  
Risk Groups ◽  
Older Age ◽  
Reproductive Age ◽  
Term Care ◽  
Severity Of The Disease ◽  
Lower Incidence Rate ◽  
The Impact

AbstractMale sex and older age have been reported to be associated with worse outcomes from COVID-19. It was postulated that estrogens may play a role in reducing the severity of the disease and may therefore offer a treatment option for COVID-19 patients. However, more female cases and deaths from COVID-19 have been recorded in Canada. To determine the potential role of estrogens, we analyzed COVID-19 data from Canada, focusing on the impact of sex and age. Although the overall incidence rate is higher in females than in males, when several high risk groups, including health care workers and long-term care residences, which are predominantly females, were excluded, we found that females had a lower incidence rate than males between the ages of 20s to 70s. Interestingly, this sex-based difference is more evident in females of the reproductive ages (20–49) than in postmenopausal patients (60s or older). Males have significantly higher hospitalization, ICU admission, and case fatality rates; however, a greater difference was observed in the older age groups. Finally, symptom manifestation varied between sexes. Some of the symptoms, which were more frequently observed in patients who recovered than patients who died, were more commonly observed in females of the reproductive age compared to their male counterparts. Since only females of the reproductive age have much higher circulating estrogens than males, these findings suggest that estrogens may play a role in reducing COVID-19 incidence and in the development of symptoms, especially those related to better survival.

scholarly journals Evaluating the Effectiveness of the Impact of Antiresorptive Drugs on Quality of Life Indicators in Women of Older Age Groups with Systemic Osteoporosis

2015 ◽  
Vol 0 (2.18) ◽  
pp. 50-54
Author(s):  
V.V. Povoroznyuk ◽  
T.V. Orlyk ◽  
N.I. Dzerovych ◽  
N.V. Grygorieva ◽  
M.A. Bystrytska ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Age Groups ◽  
Older Age ◽  
Quality Of Life Indicators ◽  
Antiresorptive Drugs ◽  
The Impact

scholarly journals Forecasting the impact of population ageing on tuberculosis incidence

2019 ◽  
Author(s):  
Chu-Chang Ku ◽  
Peter J Dodd
Keyword(s):  
Demographic Change ◽  
Prediction Interval ◽  
Temporal Trends ◽  
Age Groups ◽  
Incidence Rates ◽  
Population Ageing ◽  
Older Age ◽  
World Health ◽  
Care Needs ◽  
The Impact

AbstractBackgroundTuberculosis (TB) disease reactivates from distant latent infection or recent (re)infection. Progression risks increase with age. Across the World Health Organisation Western Pacific region, many populations are ageing and have the highest per capita TB incidence rates in older age groups. However, methods for analysing age-specific TB incidence and forecasting epidemic trends while accounting for demographic change remain limited.MethodsWe applied the Lee-Carter models, which were originally developed for mortality modelling, to model the temporal trends in age-specific TB incidence data from 2005 to 2018 in Taiwan. Females and males were modelled separately. We combined our demographic forecasts, and age-specific TB incidence forecasts to project TB incidence until 2035. We compared TB incidence projections with demography fixed in 2018 to projections accounting for demographic change.ResultsOur models quantified increasing incidence rates with age and declining temporal trends. By 2035, the forecast suggests that the TB incidence rate in Taiwan will decrease by 54% (95% Prediction Interval (PI): 45%-59%) compared to 2015, while most age-specific incidence rates will reduce by more than 60%. In 2035, adults aged 65 and above will make up 78% of incident TB cases. Forecast TB incidence in 2035 accounting for demographic change will be 39% (95% PI: 36%-42%) higher than without population ageing.ConclusionsAge-specific incidence forecasts coupled with demographic forecasts can inform the impact of population ageing on TB epidemics. The TB control programme in Taiwan should develop plans specific to older age groups and their care needs.

scholarly journals EFFECT OF CHRONIC GENERALIZED PERIODONTITIS OF MODERATE SEVERITY PATIENTS QUALITY OF LIFE

2013 ◽  
Vol 9 (6) ◽  
pp. 12-16
Author(s):  
Р. Буляков ◽  
R. Bulyakov ◽  
Р. Сабитова ◽  
R. Sabitova ◽  
О. Гуляева ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Age Groups ◽  
Acute Stage ◽  
Older Age ◽  
Duration Of Treatment ◽  
Self Assessment ◽  
Moderate Severity ◽  
Clinical Observations ◽  
The Impact

<p>In order to assess the impact of chronic generalized periodontitis of moderate severity in the acute stage to the quality of life of patients, depending on age and its dynamics on the background of the therapy were examined and interviewed 60 people. Based on the analysis of subjective self-assessment using a questionnaire oHip-49-Ru and clinical observations found a direct dependence of the quality of life of the age, which manifests itself in a lower level it initially and after therapy despite an identical diagnosis and amount of treatment in patients over 45 years, which may serve as a basis for increasing the volume or duration of treatment with the same diagnosis in patients older age groups.</p>

scholarly journals Age differences in privacy attitudes, literacy and privacy management on Facebook

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Murat Kezer ◽  
Barış Sevi ◽  
Zeynep Cemalcilar ◽  
Lemi Baruh
Keyword(s):  
Young Adults ◽  
Age Groups ◽  
Older Age ◽  
Online Privacy ◽  
Privacy Management ◽  
Protective Behavior ◽  
Convenience Sample ◽  
Adult Age ◽  
Mature Adults ◽  
The Impact

Privacy has been identified as a hot button issue in literature on Social Network Sites (SNSs). While considerable research has been conducted with teenagers and young adults, scant attention has been paid to differences among adult age groups regarding privacy management behavior. With a multidimensional approach to privacy attitudes, we investigate Facebook use, privacy attitudes, online privacy literacy, disclosure, and privacy protective behavior on Facebook across three adult age groups (18-40, 41-65, and 65+). The sample consisted of an online convenience sample of 518 adult Facebook users. Comparisons suggested that although age groups were comparable in terms of general Internet use and online privacy literacy, younger groups were more likely to use SNSs more frequently, use Facebook for social interaction purposes, and have larger networks. Also, younger adults were more likely to self-disclose and engage in privacy protective behaviors on Facebook. In terms of privacy attitudes, older age groups were more likely to be concerned about privacy of other individuals. In general, all dimensions of privacy attitudes (i.e., belief that privacy is a right, being concerned about one’s privacy, belief that one’s privacy is contingent on others, being concerned about protecting privacy of others) were positively correlated with engagement in privacy protective behavior on Facebook. A mediation model demonstrated that amount of disclosure mediated the relationship between age groups and privacy protective behavior on Facebook. Finally, ANCOVA suggested that the impact of privacy attitudes on privacy protective behavior was stronger among mature adults. Also, unlike older age groups, among young adults, considering privacy as a right or being concerned about privacy of other individuals had no impact on privacy protective behavior.

Retrospective Analysis of Clinical Parameters and Survival Data in Patients with Chronic Lymphocytic Leukemia of Younger Versus Older Age Groups.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 5001-5001
Author(s):  
Abraham Klepfish ◽  
M. Sarid ◽  
M. Basalov ◽  
H. Ghoti ◽  
E.A. Rachmilewitz
Keyword(s):  
General Population ◽  
Survival Data ◽  
Older Patients ◽  
Survival Curve ◽  
Severe Disease ◽  
Age Groups ◽  
Lymphocytic Leukemia ◽  
Older Age ◽  
Younger Patients ◽  
The Impact

Abstract Background Chronic lymphocytic leukemia (CLL), a chronic proliferative disorder of mature-looking B-lymphocytes, is the most common leukemia in the western world. CLL is a disease of elderly, with only 10–15% of patients affected at the age of less than 50 years. It is still controversial whether the clinical features and the impact on survival are different between younger and older patients, since the standard statistical methods produce contradicting results. In the present retrospective study of 87 CLL patients, we compared the data between patients above and below 65 years. The analysis of the impact of the disease on survival was carried out using a method described below. Methods Medical records and survival data were obtained from 87 patients with CLL treated in our Institute between 1983 and 2003. Statistical analysis of the clinical and laboratory parameters and survival data was performed using standard methods. The survival loss due to the disease as a percent of the expected survival of gender- and age-matched general population was determined, based on the survival analysis method developed and published recently [Klepfish A et al Am J Med.2005;118:567]. In brief, the age- and gender-matched expected survival in the general population was calculated (data obtained from the Central Government Bureau of Statistics). We used the 7th percentile survival (SPS) for further calculation in order to match the duration of the follow-up period between the patients and the general population. The survival loss was calculated by the formula: [(SPSControl - SPSPatients):SPSControl] x 100%. Results The mean age in the younger and older age groups was 56 and 74 years respectively. The male-to-female ratio was 2:1 in both age groups. The disease was found to be twice more common in patients from Ashkenazi compared with Sephardic descent. The younger group of patients had several features indicative of a more severe disease at presentation: advanced stage (Rai 2–4) – 46% vs. 16%, and diffuse involvement of bone marrow −60% vs. 18%. Younger patients were also more likely to require treatment (30% vs. 8% for fludarabine-containing regimens). Although according to the Kaplan-Meyer curve (see Fig.) a more favorable survival was shown for the younger group, the survival loss showed a reversed pattern. While the older patients lost 10% of the SPS, the survival loss in the younger patients was 44% (p=0.001). Conclusions CLL shows a strong male predominance and is more common in Ashkenazi than in Sephardic Jewish population in all ages. CLL has a more unfavorable presentation and a more severe clinical course in the younger patients (age<66) than in the older age group (age>65). The negative impact of the disease on the survival of CLL patients is higher in the younger patients, since their survival loss in comparison with the matched general population was 4.4 times higher, than that of the older patients. This mode of statistical evaluation confirms the impression that CLL is a more severe disease in younger patients. Fig: Kaplan - Meyer Survival Curve of CLL Patients Fig:. Kaplan - Meyer Survival Curve of CLL Patients

The Effect of Older Age on the Perioperative Outcomes of Spinal Fusion Surgery in Patients With Lumbar Degenerative Disc Disease With Spondylolisthesis: A Propensity Score-Matched Analysis

Neurosurgery ◽  
2019 ◽  
Vol 87 (4) ◽  
pp. 672-678
Author(s):  
Jetan H Badhiwala ◽  
Brij S Karmur ◽  
Laureen D Hachem ◽  
Jamie R F Wilson ◽  
Fan Jiang ◽  
...  
Keyword(s):  
Older Adults ◽  
Propensity Score ◽  
Spinal Fusion ◽  
Age Groups ◽  
Older Age ◽  
Perioperative Outcomes ◽  
Age Group ◽  
Improvement Program ◽  
Steroid Use ◽  
The Impact

Abstract BACKGROUND Degenerative spondylolisthesis (DS) is often treated with lumbar spinal fusion (LSF). However, there is concern that the morbidity of LSF may be prohibitively high in older adults. OBJECTIVE To evaluate the impact of advanced age on the safety of LSF for DS. METHODS Patients who underwent LSF for DS were retrospectively identified from National Surgical Quality Improvement Program datasets for 2011 to 2015 using Current Procedural Terminology codes. Data on demographic characteristics, comorbidities, surgical factors, and 30-d morbidity and mortality were collected. Propensity score matching (nearest neighbor) was performed with age (&lt;70 vs ≥70 yr) as the dependent variable and sex, type of fusion procedure, number of levels fused, diabetes, smoking, hypertension, and chronic steroid use as covariates. Outcomes were compared between age &lt;70 and ≥70 groups. RESULTS The study cohort consisted of 2238 patients (n = 1119, age &lt;70; n = 1119, age ≥70). The 2 age groups were balanced for key covariates including sex, race, diabetes, hypertension, CHF, smoking, chronic steroid use, type of fusion, and number of levels. Rates of all complications were similar between younger and older age groups, except urinary tract infection, which was more frequent among the ≥70 age group (OR 2.32, P = .009). Further, patients in the older age group were more likely to be discharged to a rehabilitation (OR 2.94, P &lt; .001) or skilled care (OR 3.66, P &lt; .001) facility, rather than directly home (OR 0.25, P &lt; .001). CONCLUSION LSF may be performed safely in older adults with DS. Our results suggest older age alone should not exclude a patient from undergoing lumbar fusion for DS.

scholarly journals SUN-625 The Impact of Age on Outcomes of Hyperosmolar Hyperglycemia Among Adult Patients with Diabetes. from the National Inpatient Sample

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Fatima Ahmed ◽  
Ashraf Abugroun ◽  
Manar Elhassan ◽  
Berhane Seyoum
Keyword(s):  
Middle Age ◽  
Age Groups ◽  
Adverse Outcomes ◽  
Older Age ◽  
National Inpatient Sample ◽  
Total Cost ◽  
Patients With Diabetes ◽  
The Mean ◽  
Secondary Outcomes ◽  
The Impact

Abstract Objective: There is paucity of literature on the impact of age on outcomes hyperosmolar hyperglycemic state (HHS) among adult patients with diabetes. The aim of the study was to evaluate the effect of age on the outcome of patients admitted for the management of HHS. Methodology: The National Inpatient Sample (NIS) was queried for all patients who were admitted with a diagnosis of HHS during the years 2005-2014. The primary outcomes of the study were all-cause mortality, acute myocardial infarction (MI), and acute stroke. The secondary outcomes were acute kidney injury (AKI), rhabdomyolysis, acute respiratory failure (ARF), need for mechanical ventilation (MV) length of stay (LOS), and total cost of stay. Results: Overall, 188,725 patients were admitted for HHS. Mean age was 55.9, standard error of the mean (SEM): 0.1. Majority were of middle age. Females were (43.9%), Caucasians were 37.4% while African Americans were 35.2%. Total mortality was 1.1%, MI was 1.3% and stroke was 1.1%. Most common secondary outcome was AKI seen in 31.3% followed by ARF seen in 2.9% of total. The mean cost was 7887 $ (SEM: 84.6) and mean LOS was 4.1 days (SEM: 0.03). Young age was defined as age ≤ 35 years, middle age was &gt; 35 and ≤ 65 years, old age was &gt; 65 years. Mortality was 0.3 %, 0.6%, 2.5% in young, middle and older aged groups respectively. Similarly, higher age correlated with increased risk for MI, stroke and all secondary outcomes. On multivariable analysis, age was an independent predictor for all adverse outcomes. Compared to young patients, middle and older age groups had higher odds for mortality with adjusted odds ratio (aOR) 2.23 [95%CI:1.10-4.52], p=0.03 and aOR 7.35 [95%CI: 3.27-16.53], p&lt;0.001 respectively, higher risk for stroke with aOR 9.32 [95%CI: 2.92-29.7], p&lt;0.001 and aOR 17.46 [95%CI:5.23-58.3], p&lt;0.001 and higher risk for MI aOR 5.18 [95%CI:2.15-12.51], p&lt;0.00 and aOR 5.80 [95%CI:2.27-14.80], p&lt;0.00 for middle and older age groups respectively. In addition, compared to the younge age group, the risk for rhabdomyolysis, AKI, ARF, MV, total cost and LOS was significantly higher among middle and older age groups respectively. Conclusion: Age is an important determinant for adverse outcomes among patients with hyperosmolar hyperglycemic sate.

scholarly journals Incidence, clinical features, and outcomes of COVID-19 in Canada: Impact of sex and age

2020 ◽  
Author(s):  
Jacob O’Brien ◽  
Kevin Y. Du ◽  
Chun Peng
Keyword(s):  
Incidence Rate ◽  
Age Groups ◽  
Case Fatality ◽  
Risk Groups ◽  
Older Age ◽  
Reproductive Age ◽  
Term Care ◽  
Severity Of The Disease ◽  
Lower Incidence Rate ◽  
The Impact

Abstract Male sex and older age have been reported to be associated with worse outcomes from COVID-19. It was postulated that estrogens may play a role in reducing the severity of the disease and may therefore offer a treatment option for COVID-19 patients. However, more female cases and deaths from COVID-19 have been recorded in Canada. To determine the impact of sex and the potential role of estrogens, we analyzed COVID-19 data, focusing on the impact of sex and age. Although the overall incidence rate is higher in females than in males, when several high risk groups, including health care workers and long-term care residences, which are predominantly females, were excluded, we found that females had a lower incidence rate than males between the ages of 20s to 70s. Interestingly, this sex-based difference is more evident in females of the reproductive ages (20-49) than in postmenopausal patients (60s or older). Males have significantly higher hospitalization, ICU admission, and case fatality rates; however, a greater difference was observed in the older age groups. Finally, symptom manifestation varied between sexes. Some of the symptoms, which were more frequently observed in patients who recovered than patients who died, were more commonly observed in females of the reproductive age compared to their male counterparts. Since only females of the reproductive age have much higher circulating estrogens than males, these findings suggest that estrogens may play a role in reducing COVID-19 incidence and in the development of symptoms, especially those related to better survival.

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