Preparation, antibacterial activity and pH-responsive release behavior of silver sulfadiazine loaded bacterial cellulose for wound dressing applications

2016 ◽  
Vol 63 ◽  
pp. 404-410 ◽  
Author(s):  
Wei Shao ◽  
Hui Liu ◽  
Jimin Wu ◽  
Shuxia Wang ◽  
Xiufeng Liu ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Cellulose ◽  
Wound Dressing ◽  
Silver Sulfadiazine ◽  
Release Behavior ◽  
Ph Responsive

scholarly journals Graphene oxide/silver nanohybrid: Optimization, antibacterial activity and its impregnation on bacterial cellulose as a potential wound dressing based on GO-Ag nanocomposite-coated BC

2018 ◽  
Vol 18 (5) ◽  
pp. 298-307 ◽  
Author(s):  
Javad Mohammadnejad ◽  
Fatemeh Yazdian ◽  
Meisam Omidi ◽  
Arash Darzian Rostami ◽  
Behnam Rasekh ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Graphene Oxide ◽  
Bacterial Cellulose ◽  
Wound Dressing

scholarly journals Bacterial Nanocellulose-Enhanced Alginate Double-Network Hydrogels Cross-Linked with Six Metal Cations for Antibacterial Wound Dressing

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2683
Author(s):  
Mina Shahriari-Khalaji ◽  
Siyi Hong ◽  
Gaoquan Hu ◽  
Ying Ji ◽  
Feng F. Hong
Keyword(s):  
Mechanical Properties ◽  
Antibacterial Activity ◽  
Wound Dressing ◽  
Biomedical Applications ◽  
Antibacterial Activities ◽  
Ph Responsive ◽  
Time Saving ◽  
Bacterial Nanocellulose ◽  
Vacuum Suction ◽  
Copper Zinc

Alginate (Alg) and bacterial nanocellulose (BNC) have exhibited great potential in biomedical applications, especially wound dressing. Non-toxicity and a moisture-maintaining nature are common features making them favorable for functional dressing fabrication. BNC is a natural biopolymer that promotes major advances to the current and future biomedical materials, especially in a flat or tubular membrane form with excellent mechanical strength at hydrated state. The main drawback limiting wide applications of both BNC and Alg is the lack of antibacterial activity, furthermore, the inherent poor mechanical property of Alg leads to the requirement of a secondary dressing in clinical treatment. To fabricate composite dressings with antibacterial activity and better mechanical properties, sodium alginate was efficiently incorporated into the BNC matrix using a time-saving vacuum suction method followed by cross-linking through immersion in separate solutions of six cations (manganese, cobalt, copper, zinc, silver, and cerium). The results showed the fabricated composites had not only pH-responsive antibacterial activities but also improved mechanical properties, which are capable of acting as smart dressings. All composites showed non-toxicity toward fibroblast cells. Rat model evaluation showed the skin wounds covered by the dressings healed faster than by BNC.

scholarly journals Permeation of Silver Sulfadiazine Into TEMPO-Oxidized Bacterial Cellulose as an Antibacterial Agent

2021 ◽  
Vol 8 ◽  
Author(s):  
Shahia Khattak ◽  
Xiao-Tong Qin ◽  
Fazli Wahid ◽  
Long-Hui Huang ◽  
Yan-Yan Xie ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Cellulose ◽  
Oxidation Mechanism ◽  
Surface Oxidation ◽  
Average Diameter ◽  
Silver Sulfadiazine ◽  
Degree Of Crystallinity ◽  
Diffusion Method ◽  
Potential Candidate ◽  
Mediated Oxidation

Surface oxidation of bacterial cellulose (BC) was done with the TEMPO-mediated oxidation mechanism system. After that, TEMPO-oxidized bacterial cellulose (TOBC) was impregnated with silver sulfadiazine (AgSD) to prepare nanocomposite membranes. Fourier transform infrared spectroscopy (FTIR) was carried out to determine the existence of aldehyde groups on BC nanofibers and X-ray diffraction (XRD) demonstrated the degree of crystallinity. FESEM analysis revealed the impregnation of AgSD nanoparticles at TOBC nanocomposites with the average diameter size ranging from 11 nm to 17.5 nm. The sample OBCS3 showed higher antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli by the disc diffusion method. The results showed AgSD content, dependent antibacterial activity against all tested bacteria, and degree of crystallinity increases with TOBC and AgSD. The main advantage of the applications of TEMPO-mediated oxidation to BC nanofibers is that the crystallinity of BC nanofibers is unchanged and increased after the oxidation. Also enhanced the reactivity of BC as it is one of the most promising method for cellulose fabrication and functionalization. We believe that the novel composite membrane could be a potential candidate for biomedical applications like wound dressing, BC scaffold, and tissue engineering.

Impregnation of silver sulfadiazine into bacterial cellulose for antimicrobial and biocompatible wound dressing

2012 ◽  
Vol 7 (6) ◽  
pp. 065006 ◽  
Author(s):  
Jiabin Luan ◽  
Jian Wu ◽  
Yudong Zheng ◽  
Wenhui Song ◽  
Guojie Wang ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Wound Dressing ◽  
Silver Sulfadiazine

scholarly journals Preparation and Swelling Behaviors of High-Strength Hemicellulose-g-Polydopamine Composite Hydrogels

Materials ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 186
Author(s):  
Jiayan Ge ◽  
Kaiqi Gu ◽  
Kewen Sun ◽  
Xinyue Wang ◽  
Shuangquan Yao ◽  
...  
Keyword(s):  
Water Retention ◽  
High Strength ◽  
Release Behavior ◽  
Ph Responsive ◽  
Composite Hydrogels ◽  
Hydrogel Network ◽  
Microsphere Size ◽  
Chemical Cross Linking ◽  
Swelling Behaviors ◽  
Good Water Retention

Hemicellulose-based composite hydrogels were successfully prepared by adding polydopamine (PDA) microspheres as reinforcing agents. The effects of PDA microsphere size, dosage, and nitrogen content in hydrogel on the mechanical and rheological properties was studied. The compressive strength of hydrogel was increased from 0.11 to 0.30 MPa. The storage modulus G’ was increased from 7.9 to 22.0 KPa. The gaps in the hemicellulose network are filled with PDA microspheres. There is also chemical cross-linking between them. These gaps increased the density of the hydrogel network structure. It also has good water retention and pH sensitivity. The maximum cumulative release rate of methylene blue was 62.82%. The results showed that the release behavior of hydrogel was pH-responsive, which was beneficial to realizing targeted and controlling drug release.

Electrospun Sandwich-Structure Composite Membranes for Wound Dressing Scaffolds with High Antioxidant and Antibacterial Activity

2017 ◽  
Vol 303 (2) ◽  
pp. 1700270 ◽  
Author(s):  
Jinzhen Li ◽  
Yang Hu ◽  
Ting He ◽  
Mengwen Huang ◽  
Xiangchao Zhang ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Wound Dressing ◽  
Sandwich Structure ◽  
Composite Membranes

Biosynthesis of Carboxymethylated Bacterial Cellulose Composite for Wound Dressing

2011 ◽  
Vol 685 ◽  
pp. 322-326 ◽  
Author(s):  
Jun Wei Yu ◽  
Xiao Li Liu ◽  
Chang Sheng Liu ◽  
Dong Ping Sun
Keyword(s):  
Bacterial Cellulose ◽  
Wound Dressing ◽  
Culture Medium ◽  
Acetobacter Xylinum ◽  
Water Holding Capacity ◽  
Water Soluble ◽  
Transmission Rates ◽  
Measurement Results ◽  
Water Holding ◽  
Cellulose Composite

A novel bacterial cellulose (BC) composite (carboxymethylated-bacterial cellulose, CM-BC) was synthesized by Acetobacter xylinum by adding water-soluble carboxymethylated cellulose (CMC) in the culture medium. FTIR results showed that CM-BC is obtained by the incorporation of CMC in the network of BC. Water-holding capacity and water vapor transmission rates (WVTR) of CM-BC and BC are determined. The WVTR of CM-BC is comparable to that of BC, but the water-holding capacity of CM-BC is improved compared with BC. Tensile strengths measurement results showed that the fracture stress of CM-BC is higher than that of BC, indicating that CM-BC have more potential wound dressing applications than BC.

scholarly journals Investigation of Nano Bacterial Cellulose Coated by Sesamum Oil for Wound Dressing Application

2015 ◽  
Vol 11 ◽  
pp. 212-216 ◽  
Author(s):  
A. Meftahi ◽  
D. Nasrolahi ◽  
V. Babaeipour ◽  
S. Alibakhshi ◽  
S. Shahbazi
Keyword(s):  
Bacterial Cellulose ◽  
Wound Dressing
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