scholarly journals Bio-inspired synthesis of PbO nanoparticles (NPs) via an aqueous extract of Rosmarinus officinalis (rosemary) leaves

2020 ◽  
Author(s):  
S.K. Noukelag ◽  
H.E.A. Mohamed ◽  
L.C. Razanamahandry ◽  
S.K.O. Ntwampe ◽  
C.J. Arendse
Keyword(s):  
Aqueous Extract ◽  
Rosmarinus Officinalis ◽  
Pbo Nanoparticles

scholarly journals PROTECTIVE ROLE AND ANTIOXIDANT ACTIVITY OF AQUEOUS EXTRACT OF ROSMARINUS OFFICINALIS AGAINST TRICHLOROACETATE-INDUCED TOXICITY IN LIVER OF MALE RATS

2018 ◽  
Vol 11 (6) ◽  
pp. 420
Author(s):  
Medhat Mostafa Abozid ◽  
Hoda Ea Farid
Keyword(s):  
Aqueous Extract ◽  
Liver Damage ◽  
Protective Role ◽  
Rosmarinus Officinalis ◽  
Male Rats ◽  
Control Group ◽  
Albino Rats ◽  
Gamma Glutamyl Transferase ◽  
Group I ◽  
Glutamyl Transferase

 Objective: The current study was designed to estimate the potential protective role of the aqueous extract of rosemary (AER) (Rosmarinus officinalis) against trichloroacetic acid (TCA)-created hepatotoxicity in male albino rats.Methods: Forty male albino rats were separated into four groups of ten: Group I served as control; Group II was given AER (200 mg/kg/day) by gavage; Group III received TCA at the dose 50 mg/kg/day, and Group V was treated with AER (200 mg/kg/day) and received TCA (50 mg/kg/day). The experiment was carried out for 2 months.Results: The toxicity of TCA for rats was revealed by an elevation in liver marker enzymes activities (gamma-glutamyl transferase [GGT], alkaline phosphatase [ALP], aspartate transaminase [AST], alanine aminotransferase [ALT]) and conjugated bilirubin (CB) level, and a decrease in albumin and total protein (TP) levels. The TCA administration also caused a significant increase in the activities of catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD), and also malondialdehyde (MDA) level in liver tissues. These biochemical effects were accompanied by histological indicators of liver damage. Treatment with ARE recovered the liver damage instigated by TCA, as showed by perfection of liver enzyme markers (GGT, ALT, AST, ALP), CB, TP and albumin; as well as antioxidant parameters (CAT, SOD, GPx) and lipid peroxidation (MDA) and amelioration of histopathology changes in the liver tissues.Conclusion: It could be concluded that AER supplementation for 2 months in TCA-induced toxicity in rats benefited hepatic antioxidant status and improved liver injury and damage in male albino rats exposed to TCA.

scholarly journals Effect of Aluminium and Aqueous extract of Rosmarinus officinalis on rat Brain: Impact on Neurobehavioral and Histological study

2020 ◽  
Vol 10 (4) ◽  
pp. 179-187
Author(s):  
Zakia Lahouel ◽  
Omar Kharoubi ◽  
Amina Boussadia ◽  
Zohra Bekkouche ◽  
Abdelkader Aoues
Keyword(s):  
Cerebral Cortex ◽  
Aqueous Extract ◽  
Histological Study ◽  
Significant Inhibition ◽  
Rosmarinus Officinalis ◽  
Rosemary Extract ◽  
Anxiety State ◽  
Weekly Dose ◽  
Ca1 Region ◽  
Corrective Effect

'Rosmarinus officilnalis' is a plant used in Mediterranean diet and traditional medicine, possessing various antioxidant and cytoprotective bioactivities. In this study, we investigated the potential neuroprotective efficacy of aqueous Rosemary extract (AER) against neurotoxicity induced by Aluminum (Al), in terms of behavioral, biochemical and histological aspects in young rats. an intraperitoneal injection of Al, at the weekly dose of 60mg/Kg was given to the animals. A treatment of 150mg/Kg/day of AER was administered by gavage over periods of 6 or 12weeks. Al caused intense changes over time in body and brain weight, increase in neurological disorders such as depression, anxiety, and deficiency in memory skills. Results show also disturbances in locomotors activity, with a significant inhibition of AchE and increase LDH activity compared to control. Additionally, Al induced structural damages in the cerebral cortex, and the CA1 region of hippocampus. However, treatment with AER resulted in improved depression and anxiety state, locomotors activity and restored memory skills. Results show that AER increase the AchE activity and decreased neuronal loss in the cerebral cortex and the CA1 region of hippocampus with the 6weeks treatment but induced disruption and structural modification of brain tissue after the 12 weeks treatment. The Aqueous extract of Rosemary possess a neuroprotector and corrective effect against neurological alterations induced by Aluminum, but when administered over a long period of time, the extract can cause a no beneficial effect and morphologic modifications in cerebral tissue and behavior test. Keywords: Rosmarinus officinalis, Aluminum, neuro-behavior, brain structure.

Green synthesis of sulfur nanoparticles using Rosmarinus officinalis leaves extract and nematicidal activity against Meloidogyne javanica

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Electron Microscopy ◽  
Aqueous Extract ◽  
Sodium Thiosulfate ◽  
Meloidogyne Javanica ◽  
Rosmarinus Officinalis ◽  
Root Knot Nematode ◽  
Second Stage ◽  
Xrd Techniques ◽  
Average Size ◽  
Sulfur Nanoparticles

Sulfur nanoparticles (S-NPs) were prepared using rosemary (Rosmarinus officinalis) leaves aqueous extract and sodium thiosulfate pentahydrate (Na2S2O3.5H2O) at room temperature. The S-NPs were characterized by UV–visible spectrophotometer, Fourier transform infrared (FT-IR), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), and X-ray diffraction (XRD) techniques. The sulfur nanoparticles are crystalline in nature with average size of 40 nm. The morphology of S-NPs could be controlled by tuning the amount of rosemary leaves aqueous extract and sulfur ions. The cytotoxic effects of the S-NPs on hatching of second stage root-knot and mortality of second stage of root-knot nematode (Meloidogyne javanica) were tested. These results confirmed that the S-NPs synthesized using rosemary leaves aqueous extract and could possibility be used as nematicidal to manage M. javanica infestation.

scholarly journals Mutagenic and antimutagenic effects of aqueous extract of rosemary (Rosmarinus officinalis L.) on meristematic cells of Allium cepa

2014 ◽  
Vol 13 (4) ◽  
pp. 9986-9996 ◽  
Author(s):  
I. Felicidade ◽  
J.D. Lima ◽  
J.R. Pesarini ◽  
A.C.D. Monreal ◽  
M.S. Mantovani ◽  
...  
Keyword(s):  
Allium Cepa ◽  
Aqueous Extract ◽  
Rosmarinus Officinalis ◽  
Meristematic Cells ◽  
Rosmarinus Officinalis L

Effect of Rosmarinus Officinalis Aqueous Extract on Some Biochemical Barameters and Histological Characteristics of Aorta in Hyperlipidemia Male Rats

2020 ◽  
pp. 23-26
Keyword(s):  
Aqueous Extract ◽  
Rosmarinus Officinalis ◽  
Infected Group ◽  
Male Rats ◽  
Control Group ◽  
Negative Group ◽  
Positive Group ◽  
Fourth Group ◽  
Normal Water ◽  
Histological Characteristics

The present study was aimed to investigate Rosmarinus officinalis aqueous extract activity in male rats with hyperlipidemia. Twenty adult albino male rats were used and divided into following groups (each group consist 5 rats); negative group received ad libidium, positive group was given normal water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia. Third group rats with hyperlipidemia and treated with (50mg/kg/daily), fourth group rats with hyperlipidemia and treated with (100mg/kg/daily), The results showede high significant increase (P < 0.05) in levels of cholesterol and triglyceride and significant decrease (P < 0.05) in levels of HDL in positive group compare with control group. Oxidative stress factor in an infected group significant increase (P < 0.05) in levels of MDA (malonedialdehyied) and significant decrease (P < 0.05) in levels of glutathione (GSH) compare with control group. On the other hand, diameters of aorta artery show significant increase (P < 0.05) compare with control group. While, after using Rosmarinus officinalis aqueous extract in treatment, the results showed non-significant changes (P < 0.05) in lipid profile, MDA, GSH and diameters of aorta artery compare with control group. It was concluded that R. officinalis extract has been a protective effect in rats with hyperlipidemia.

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