The one year exercise and lifestyle intervention program KLAKS: Effects on anthropometric parameters, cardiometabolic risk factors and glycemic control in childhood obesity

Metabolism ◽  
2014 ◽  
Vol 63 (3) ◽  
pp. 422-430 ◽  
Author(s):  
Susann Blüher ◽  
David Petroff ◽  
Antje Wagner ◽  
Katja Warich ◽  
Ruth Gausche ◽  
...  
2016 ◽  
Vol 8 (9) ◽  
pp. 322 ◽  
Author(s):  
Mariam Kashani ◽  
Arn H Eliasson ◽  
Elaine M Walizer ◽  
Clarie E Fuller ◽  
Renata J Engler ◽  
...  

<p><strong>BACKGROUND:</strong> Self-efficacy, defined as confidence in the ability to carry out behavior to achieve a desired goal, is considered to be a prerequisite for behavior change. Self-efficacy correlates with cardiovascular health although optimal timing to incorporate self-efficacy strategies is not well established. We sought to study the effect of an empowerment approach implemented in the introductory phase of a multicomponent lifestyle intervention on cardiovascular health outcomes.</p><p><strong>DESIGN:</strong> Prospective intervention cohort study.</p><p><strong>METHODS:</strong> Patients in the Integrative Cardiac Health Project Registry, a prospective lifestyle change program for the prevention of cardiovascular disease were analyzed for behavioral changes by survey, at baseline and one year, in the domains of nutrition, exercise, stress management and sleep. Self-efficacy questionnaires were administered at baseline and after the empowerment intervention, at 8 weeks.</p><p><strong>RESULTS:</strong> Of 119 consecutive registry completers, 60 comprised a high self-efficacy group (scoring at or above the median of 36 points) and 59 the low self-efficacy group (scoring below median).  Self-efficacy scores increased irrespective of baseline self-efficacy but the largest gains in self-efficacy occurred in patients who ranked in the lower half for self-efficacy at baseline. This lower self-efficacy group demonstrated behavioral gains that erased differences between the high and low self-efficacy groups. <strong></strong></p><p><strong>CONCLUSIONS:</strong> A boost to self-efficacy early in a lifestyle intervention program produces significant improvements in behavioral outcomes.  Employing empowerment in an early phase may be a critical strategy to improve self-efficacy and lower risk in individuals vulnerable to cardiovascular disease.</p>


2019 ◽  
Vol 12 (3) ◽  
pp. 1317-1328
Author(s):  
Inas R. El- Alameey ◽  
Hanaa H. Ahmed ◽  
Mones M. Abushady

Brain derived neurotrophic factor (BDNF) is a neurotrophin probably concerned in the pathophysiology of obesity and metabolic syndrome (MS) in adults. The aim was to explore serum BDNF relationship with metabolic syndrome components before and after one-year of the lifestyle intervention program in obese children. Forty obese children and forty age and gender-matched lean controls were studied. Anthropometric parameters, blood pressure, fasting blood glucose, serum insulin, lipid profile, insulin resistance (HOMA-IR), and serum BDNF, before and after one year of diet control and physical activity were measured. At baseline, fasting glucose, insulin, HOMA-IR, cholesterol, LDL, triglycerides were significantly higher in obese children relative to controls (P=0.00). Serum BDNF concentration was significantly lower in obese children than in lean controls (P=0.00), and its mean concentration of the subjects with MS was significantly lower than those without MS, and control group (P< 0.001). Linear regression analysis suggested that high waist: hip ratio, body adiposity index, fat percentage, diastolic BP, fasting blood glucose, LDL and HOMA-IR are good predictors for decreased serum BDNF concentration in obese children. After one-year intervention program, the obese group showed a significant increase in serum BDNF, and HDL, paralleled by a significant decline in fasting glucose, insulin, HOMA-IR, cholesterol, LDL, triglycerides as compared to the baseline (P =0.00). Serum BDNF was lower in obese children than in lean controls, and seemed to be linked with the metabolic syndrome components. One-year lifestyle intervention program succeeded to enhance BDNF serum concentration in these children.


2008 ◽  
Vol 101 (7) ◽  
pp. 911-918 ◽  
Author(s):  
Joanne Frattaroli ◽  
Gerdi Weidner ◽  
Terri A. Merritt-Worden ◽  
Steven Frenda ◽  
Dean Ornish

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1274
Author(s):  
Sofia I. Karampatsou ◽  
Sofia M. Genitsaridi ◽  
Athanasios Michos ◽  
Eleni Kourkouni ◽  
Georgia Kourlaba ◽  
...  

Overweight and obesity in childhood and adolescence represent major public health problems of our century, and account for increased morbidity and mortality in adult life. Irisin and Fibroblast Growth Factor 21 (FGF-21) have been proposed as prognostic and/or diagnostic biomarkers in subjects with obesity and metabolic syndrome, because they increase earlier than other traditional biomarkers. We determined the concentrations of Irisin and FGF-21 in children and adolescents with overweight and obesity before and after one year of a life-style intervention program of diet and physical exercise and explored the impact of body mass index (BMI) reduction on the concentrations of Irisin, FGF-21 and other cardiometabolic risk factors. Three hundred and ten (n = 310) children and adolescents (mean age ± SD: 10.5 ± 2.9 years) were studied prospectively. Following one year of the life-style intervention program, there was a significant decrease in BMI (p = 0.001), waist-to-hip ratio (p = 0.024), waist-to-height ratio (p = 0.024), and Irisin concentrations (p = 0.001), and an improvement in cardiometabolic risk factors. There was no alteration in FGF-21 concentrations. These findings indicate that Irisin concentrations decreased significantly as a result of BMI reduction in children and adolescents with overweight and obesity. Further studies are required to investigate the potential role of Irisin as a biomarker for monitoring the response to lifestyle interventions and for predicting the development of cardiometabolic risk factors.


2020 ◽  
Vol 25 ◽  
pp. 19-36
Author(s):  
Gerd L. Nordbotten ◽  
Leif I. Tjelta ◽  
Merete H. Helland

The aims of this study were to: 1) investigate to what extent participants in a lifestyle intervention program, including nutritional guidance and two weekly intensive running sessions, maintain improvements in aerobic capacity and health parameters one year after the end of an intervention; and 2) identify common determinants for those participants who succeeded in weight loss maintenance. A total of 51 participants completed the 33-week intervention. One year after the end of the intervention period (1YA) 34 participants completed anthropometric measurements, 12 (8 women) in the training group (TG) and 22 (13 women) in the nutritional guidance and training group (NTG). A total of 13 participants (9 women) in the TG and 11 participants (7 women) in the NTG completed a 3000 m running test. There were no significant differences in body mass index, 3000 m running time or waist circumference between the groups 1YA. There was however, substantial variation in both groups as to what extent participants had maintained their weight loss. Higher self-efficacy and self-control in relation to food and exercise characterized those who best maintained their weight loss.


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