scholarly journals The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle

2019 ◽  
Vol 21 ◽  
pp. 51-67 ◽  
Author(s):  
Timothy M. Moore ◽  
Zhenqi Zhou ◽  
Whitaker Cohn ◽  
Frode Norheim ◽  
Amanda J. Lin ◽  
...  
2021 ◽  
Vol 37 (1) ◽  
pp. 19-28
Author(s):  
Endre Szabó ◽  
Katinka Bajkai-Tóth ◽  
Ildikó Rudnák ◽  
Róbert Magda

In the course of the research, we examined the impact of the selection and training system of a Hungarian automotive company on organizational performance, which together ensure the future development of the company. It contributes to the optimization of sales, purchasing and logistics processes, ensures customer satisfaction and the success of the company. In this fast-paced and globalized world, it is essential for companies to be aware that one of the most important factors of production is human resources themselves, whose proper selection and training are a key element in maintaining and developing economic competitiveness. Human resources play the biggest role in the operation of an economic organization. Process quality and process orientation reduce costs, increase profitability, and improve processes to always meet growing requirements. This is the basis of the quality strategy. Therefore, it consistently applies preventive quality assurance methods, learns from failures, eliminates the causes of mistakes without delays and transfers its experience to all areas of the company for preventive action. It is customer-oriented and strives for excellence in all areas, and thus makes it an obligation for everyone to aim for the highest level of customer service. Due to the special peculiarities and characteristics of the labor force, it cannot be compared to any of the production resources. Taking this as a basis, the human resource management used to be more of a functional purpose, while in recent decades human factors have become an essential source of competitiveness. The market operation and performance of an organization depends significantly on how we can select the most suitable workforce. We need to see what the strategic points that determine the role of HR are, and we are also looking for the answer in which direction the needs, expectations and professionalism given by the generational difference move the activities of human resources. The aim of the research is to get an answer to how the employees of one of the leading Hungarian players in the automotive industry perceive the importance of the selection and training of the workforce in maintaining and improving competitiveness. To this end, we used a semi-structured interview, with the help of which we evaluated the current selection and training processes in the light of competitiveness and made suggestions for the improvement and refinement of these processes.


2013 ◽  
pp. 926-937
Author(s):  
P. R. Blackwell ◽  
Darrel McDonald

During the past 20 years, the role of geospatial technology in society has increased dramatically. However, the impact of these technologies in rural areas remains minimal. In Texas, a federally funded project called the Columbia Regional Geospatial Service Center System (the System) has emerged as a model for bringing the benefits of geospatial technology to all portions of society. The model involves distributed, academically based Centers, each with regional specializations, linked together into a unified system for addressing critical needs in emergency response, economic development, and natural resource management. The Centers operate on three focus areas, i.e., data, applications, and training. The Columbia Center has been in operation for five years and has demonstrated the practical strength of the System through numerous local and statewide projects, responses to natural disasters, and other geospatial activities.


2012 ◽  
pp. 566-577
Author(s):  
P. R. Blackwell ◽  
Darrel McDonald

During the past 20 years, the role of geospatial technology in society has increased dramatically. However, the impact of these technologies in rural areas remains minimal. In Texas, a federally funded project called the Columbia Regional Geospatial Service Center System (the System) has emerged as a model for bringing the benefits of geospatial technology to all portions of society. The model involves distributed, academically based Centers, each with regional specializations, linked together into a unified system for addressing critical needs in emergency response, economic development, and natural resource management. The Centers operate on three focus areas, i.e., data, applications, and training. The Columbia Center has been in operation for five years and has demonstrated the practical strength of the System through numerous local and statewide projects, responses to natural disasters, and other geospatial activities.


1988 ◽  
Vol 32 (13) ◽  
pp. 760-764
Author(s):  
Robert F. Randolph

Leaders of task-oriented production groups play an important role in their group's functioning and performance. That role also evolves as groups mature and learn to work together more smoothly. The present study uses a functional analysis of the evolving role of supervisors of underground coal mining crews to evaluate the impact of supervisors' characteristics and behaviors on their crews' efficiency and safety, and makes recommendations for improving supervisory selection and training. Data were gathered from a sample of 138 supervisors at 13 underground coal mines. Detailed structured observations of the supervisors indicated that most of their time was spent attending to hardware and paperwork, while comparatively little time was spent on person to person “leadership”. The findings point out that while group needs changed over time, the supervisors' behaviors typically did not keep pace and probably restricted group performance.


J-Dinamika ◽  
2018 ◽  
Vol 3 (2) ◽  
Author(s):  
Bambang Utoyo ◽  
Adryade Reshi Gusta ◽  
Yan Sukmawan ◽  
Made Same

Pepper is one of the spice crops that contribute to improving the Indonesian economy. Pepper cultivation is carried out on a small scale to a large scale. Pepper propagation by cutting is considered quite effective and efficient. Politeknik Negeri Lampung has been develop the Pepper Nursery Unit since 2007. This unit runs a business in the production of climbing pepper seedling, shrub pepper seedling, and pepper nursery training. The aim of this program is to support the mission of Politeknik Negeri Lampung in preparing itself to face college campus autonomy through the acquisition of revenue from established business units, accelerating the process of developing an entrepreneurial cultural system in the campus environment, providing competency development opportunities for staff and students, and increasing the role of the Politeknik Negeri Lampung for the community, especially in agriculture. The impact of this program is the availability of hight quality pepper seedling, increasing income generating Politeknik Negeri Lampung, establishment of the Pepper Nursery Unit and training service, improving the skills of Politeknik Negeri Lampung students in pepper nursery, developing entrepreneurial potential for students and staff, as well as increasing the role of Lampung State Polytechnic in community service activities.Keywords—Campus entrepreuneurship, estate crop, nursery business.


Genes ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 81
Author(s):  
Natalia Leciejewska ◽  
Ewa Pruszyńska-Oszmałek ◽  
Karolina Mielnik ◽  
Maciej Głowacki ◽  
Tomasz P. Lehmann ◽  
...  

SPX (spexin) and its receptors GalR2 and GalR3 (galanin receptor subtype 2 and galanin receptor subtype 3) play an important role in the regulation of lipid and carbohydrate metabolism in human and animal fat tissue. However, little is still known about the role of this peptide in the metabolism of muscle. The aim of this study was to determine the impact of SPX on the metabolism, proliferation and differentiation of the skeletal muscle cell line C2C12. Moreover, we determined the effect of exercise on the SPX transduction pathway in mice skeletal muscle. We found that increased SPX, acting via GalR2 and GalR3 receptors, and ERK1/2 phosphorylation stimulated the proliferation of C2C12 cells (p < 0.01). We also noted that SPX stimulated the differentiation of C2C12 by increasing mRNA and protein levels of differentiation markers Myh, myogenin and MyoD (p < 0.01). SPX consequently promoted myoblast fusion into the myotubule (p < 0.01). Moreover, we found that, in the first stage (after 2 days) of myocyte differentiation, GalR2 and GalR3 were involved, whereas in the last stage (day six), the effect of SPX was mediated by the GalR3 isoform. We also noted that exercise stimulated SPX and GalR2 expression in mice skeletal muscle as well as an increase in SPX concentration in blood serum. These new insights may contribute to a better understanding of the role of SPX in the metabolism of skeletal muscle.


2020 ◽  
Vol 4 (2) ◽  
pp. 115-126
Author(s):  
Muhammad Ramaditya ◽  
Amirul Wahid Prihantoro

The objective of this study is analyzed the impact of organizational culture, training, and leadership on the work performance of civil workers in financial and development supervisory agency. This research uses an associative approach with simple random sampling technique which is measured by SEM using the Smart PLS 3.0 application. The population of this study was 330 civil workers in Financial and Development Supervisory Agency (BPKP). The results of the study shown that the Organizational Culture Variables did not significantly influence work Performance of the civil worker in Financial and Development Supervisory Agency, but do not pass the reliability test. Training Variables have a positive and significant effect on the work performance of the civil workers. Leadership variables have a positive and significant effect on the work performance of the civil workers in Financial and Development Supervisory Agency.


2017 ◽  
Vol 19 (3) ◽  
pp. 5
Author(s):  
Catherine E. Wilkins

Tiris article, a summary of a recent study conducted for the author's doctorial dissertation, examines issues, trends, and relevant studies on the impact of the changing environment on the role of the librarian. Based on the enquiry conducted, she clearly sees the future role of the librarian as broadly based and focused on the utilization and evaluation of information, and as a client consultant. The librarian is seen as playing a large role in the development of information services, and as an information architect. Applying the principles developed in the frame of reference created for this study to business, research and education, will assist policy makers in making decisions about resources and training which will be needed for the development of future information resource centres. Strategic advantage due to prior knowledge will be more than ever required for organizational success.


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