Targeted delivery of quercetin via pH-responsive zinc oxide nanoparticles for breast cancer therapy

2019 ◽  
Vol 100 ◽  
pp. 129-140 ◽  
Author(s):  
Pritam Sadhukhan ◽  
Mousumi Kundu ◽  
Sharmistha Chatterjee ◽  
Noyel Ghosh ◽  
Prasenjit Manna ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Zinc Oxide ◽  
Cancer Therapy ◽  
Targeted Delivery ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Ph Responsive ◽  
Breast Cancer Therapy

Frizzled-7-targeted delivery of zinc oxide nanoparticles to drug-resistant breast cancer cells

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12858-12870 ◽  
Author(s):  
Pakatip Ruenraroengsak ◽  
Darya Kiryushko ◽  
Ioannis G. Theodorou ◽  
Michał M. Klosowski ◽  
Erik R. Taylor ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Resistance ◽  
Zinc Oxide ◽  
Targeted Delivery ◽  
Zinc Oxide Nanoparticles ◽  
Breast Cancer Cells ◽  
Oxide Nanoparticles ◽  
Drug Resistant ◽  
Cancer Subtypes ◽  
Aggressive Breast Cancer

There is a need for novel strategies to treat aggressive breast cancer subtypes and overcome drug resistance.

Folic acid modified copper oxide nanoparticles for targeted delivery in in vitro and in vivo systems

RSC Advances ◽  
2015 ◽  
Vol 5 (83) ◽  
pp. 68169-68178 ◽  
Author(s):  
Dipranjan Laha ◽  
Arindam Pramanik ◽  
Sourav Chattopadhyay ◽  
Sandip kumar Dash ◽  
Somenath Roy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Therapy ◽  
Copper Oxide ◽  
Targeted Delivery ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Breast Cancer Therapy

Targeted delivery of copper oxide nanoparticles for breast cancer therapy.

scholarly journals pH-responsive and targeted delivery of curcumin via phenylboronic acid-functionalized ZnO nanoparticles for breast cancer therapy

2019 ◽  
Vol 18 ◽  
pp. 161-172 ◽  
Author(s):  
Mousumi Kundu ◽  
Pritam Sadhukhan ◽  
Noyel Ghosh ◽  
Sharmistha Chatterjee ◽  
Prasenjit Manna ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Zno Nanoparticles ◽  
Targeted Delivery ◽  
Phenylboronic Acid ◽  
Ph Responsive ◽  
Breast Cancer Therapy

scholarly journals Surface functionalisation of poly-APO-b-polyol ester cross-linked copolymers as core–shell nanoparticles for targeted breast cancer therapy

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Rida Tajau ◽  
Rosiah Rohani ◽  
Siti Selina Abdul Hamid ◽  
Zainah Adam ◽  
Siti Najila Mohd Janib ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Targeted Delivery ◽  
Particle Diameter ◽  
Core Shell ◽  
Breast Cancer Therapy ◽  
Polyol Ester ◽  
Apo B ◽  
Chemical Structures

AbstractPolymeric nanoparticles (NPs) are commonly used as nanocarriers for drug delivery, whereby their sizes can be altered for a more efficient delivery of therapeutic active agents with better efficacy. In this work, cross-linked copolymers acted as core–shell NPs from acrylated palm olein (APO) with polyol ester were synthesized via gamma radiation-induced reversible addition-fragmentation chain transfer (RAFT) polymerisation. The particle diameter of the copolymerised poly(APO-b-polyol ester) core–shell NPs was found to be less than 300 nm, have a low molecular weight (MW) of around 24 kDa, and showed a controlled MW distribution of a narrow polydispersity index (PDI) of 1.01. These properties were particularly crucial for further use in designing targeted NPs, with inclusion of peptide for the targeted delivery of paclitaxel. Moreover, the characterisation of the synthesised NPs using Fourier Transform-Infrared (FTIR) and Neutron Magnetic Resonance (NMR) analyses confirmed the possession of biodegradable hydrolysed ester in its chemical structures. Therefore, it can be concluded that the synthesised NPs produced may potentially contribute to better development of a nano-structured drug delivery system for breast cancer therapy.

Co-administration of biocompatible self-assembled polylactic acid–hyaluronic acid block copolymer nanoparticles with tumor-penetrating peptide-iRGD for metastatic breast cancer therapy

2018 ◽  
Vol 6 (19) ◽  
pp. 3163-3180 ◽  
Author(s):  
Caifeng Deng ◽  
Xiaohong Xu ◽  
Drunp Tashi ◽  
Yongmei Wu ◽  
Bingyin Su ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Hyaluronic Acid ◽  
Metastatic Breast Cancer ◽  
Block Copolymer ◽  
Cancer Therapy ◽  
Polylactic Acid ◽  
Targeted Delivery ◽  
Metastatic Breast ◽  
Chemotherapeutic Drugs ◽  
Breast Cancer Therapy

The safe and efficient targeted delivery of chemotherapeutic drugs has remained a challenge in metastatic breast cancer therapy.

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