DXA-assessed changes in body composition in obese women following two different weight loss programs

While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95% CI, −5.75, −2.88), WW (−4.31 kg; 95% CI, −5.82, −2.96), JC (−5.34 kg; 95% CI, −6.86, −3.90), NS (−5.03 kg; 95% CI, −6.49, −3.56), and control (0.16 kg, 95% CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but not WW (31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = −0.7), NS (39% vs. 50% adjres. = −1.5), or control (45% vs. 55% adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.

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Evaluation of the effect of oral taurine supplementation on levels of fibroblast growth factors, β-Klotho co-receptor, some biochemical indices and body composition in obese women on a weight-loss diet: a study protocol for a double-blind randomized controlled trial

10.21203/rs.2.219/v2 ◽

2019 ◽

Author(s):

Fatemeh Haidari ◽

Maryam Asadi ◽

Javad Mohammadi-asl ◽

Kambiz Ahmadi-angali

Keyword(s):

Weight Loss ◽

Body Composition ◽

Fibroblast Growth Factors ◽

The Other ◽

Fibroblast Growth ◽

Obese Women ◽

Double Blind ◽

Randomized Controlled ◽

Weight Loss Diet ◽

Biochemical Indices

Abstract Background: according to studies, the function of FGFs are disturbed in obesity. So that, serum level of FGFs are correlated with insulin resistance and obesity. Besides the effects of eicosapentaenoic acid on serum FGF21 concentrations, the effect of other nutrients on FGFs is not clear. Since obesity as an important health problem is rising in the world and on the other side, taurine (Tau) biosynthesis is reduced by adipose tissue-derived factors in obesity, the effects of Tau and a weight loss diet on obesity need to be investigated further. Methods: We will conduct a 2 month’s double-blind, parallel-group, randomized controlled clinical trial to investigate the effect of Tau supplementation on serum levels of fibroblast growth factors, β-Klotho co-receptor, some biochemical indices and body composition in obese women on a weight-loss diet. Discussion: we will determine the other advantages of a weight loss diet on metabolic risk factors. Moreover, for the first time, the effects of a weight loss diet along with Tau supplementation on these variables will be assessed.

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Influence of Changes in Body Composition and Adaptive Thermogenesis on the Difference between Measured and Predicted Weight Loss in Obese Women

Obesity Facts ◽

10.1159/000210369 ◽

2009 ◽

Vol 2 (2) ◽

pp. 6-6 ◽

Cited By ~ 23

Author(s):

Kristin Goele ◽

Anja Bosy-Westphal ◽

Birgit Rümcker ◽

Merit Lagerpusch ◽

Manfred J. Müller

Keyword(s):

Weight Loss ◽

Body Composition ◽

Obese Women ◽

Adaptive Thermogenesis ◽

The Difference

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Correlation between the rate of weight loss and changes in body composition in obese postmenopausal women after 5 weeks: a pilot study

Applied Physiology Nutrition and Metabolism ◽

10.1139/h08-004 ◽

2008 ◽

Vol 33 (2) ◽

pp. 347-355 ◽

Cited By ~ 4

Author(s):

Hélène Arguin ◽

Danielle R. Bouchard ◽

Mélissa Labonté ◽

André Carpentier ◽

Jean-Luc Ardilouze ◽

...

Keyword(s):

Weight Loss ◽

Body Composition ◽

Postmenopausal Women ◽

Weight Loss Intervention ◽

Obese Women ◽

X Ray ◽

Before And After ◽

The Impact ◽

Current Guidelines ◽

Similar Decrease

Approximately 25% of weight lost during restrictive diets (without exercise) is lean body mass (LBM). No study has yet investigated the impact of the rate of weight loss (RWL) on LBM and fat mass (FM). The purpose of this study was to investigate the relationships between the RWL and body composition in older obese women. Twenty obese postmenopausal women aged between 51 and 74 years enrolled in a 5 week dietary weight loss intervention. Subjects were characterized according to their RWL (low RWL < 0.74 kg·week–1 (n = 9) vs. high RWL ≥ 0.74 kg·week–1 (n = 11)). Total and trunk FM and LBM (by dual-energy X-ray absorptiometry) were measured before and after weight loss. A significant correlation was observed between the RWL (kg·week–1) and changes in LBM (kg·week–1) (r = 0.75; p = 0.0002). However, no association was observed with changes in FM (kg·week–1) (r = 0.40; p = 0.08). Both groups showed a similar decrease in FM (low RWL, –2.7 ± 0.9 kg,; high RWL, –3.2 ± 0.8 kg; p = 0.38), whereas losses in LBM were significantly higher in the high RWL than in the low RWL group (–1.6 ± 1.2 kg vs. –0.4 ± 1.1 kg; p = 0.05). An RWL > 0.74 kg·week–1 was associated with a greater loss of LBM, but had no extra benefits on FM after a 5 week weight loss program. Current guidelines, which recommend RWL up to 0.91 kg·week–1, might not be optimal to prevent decreases in LBM in postmenopausal women when no exercise is added.

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Lipoic Acid Supplementation Promotes Weight Loss and Improves Body Composition in Overweight or Obese Women: Results of a Randomized, Double-Blind, Placebo-Controlled Study

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2014.10.433 ◽

2014 ◽

Vol 76 ◽

pp. S57

Author(s):

Weijian Zhang ◽

Jonathan Purnell ◽

Clive Woffendin ◽

Cliff Pereira ◽

Alexander J Michels ◽

...

Keyword(s):

Weight Loss ◽

Body Composition ◽

Lipoic Acid ◽

Controlled Study ◽

Obese Women ◽

Double Blind ◽

Double Blind Placebo ◽

Acid Supplementation

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Push Notifications From a Mobile App to Improve the Body Composition of Overweight or Obese Women: Randomized Controlled Trial (Preprint)

10.2196/preprints.13747 ◽

2019 ◽

Cited By ~ 2

Author(s):

Alberto Hernández-Reyes ◽

Fernando Cámara-Martos ◽

Guillermo Molina Recio ◽

Rafael Molina-Luque ◽

Manuel Romero-Saldaña ◽

...

Keyword(s):

Physical Activity ◽

Clinical Trial ◽

Weight Loss ◽

Body Composition ◽

Controlled Trial ◽

Intervention Group ◽

The Body ◽

Control Group ◽

Obese Women ◽

Randomized Controlled

BACKGROUND Technology—in particular, access to the Internet from a mobile device—has forever changed the way we relate to others and how we behave in our daily life settings. In recent years, studies have been carried out to analyze the effectiveness of different actions via mobile phone in the field of health: telephone calls, short message service (SMS), telemedicine, and, more recently, the use of push notifications. We have continued to explore ways to increase user interaction with mobile apps, one of the pending subjects in the area of mHealth. By analyzing the data produced by subjects during a clinical trial, we were able to extract behavior patterns and, according to them, design effective protocols in weight loss programs. OBJECTIVE A clinical trial was proposed to (1) evaluate the efficacy of push notifications in an intervention aimed at improving the body composition of adult women who are overweight or obese, through a dietary procedure, and (2) analyze the evolution of body composition based on push notifications and prescribed physical activity (PA). METHODS A two-arm randomized controlled trial was carried out. A sample size of 117 adult obese women attended a face-to-face, 30-minute consultation once a week for 6 months. All patients were supplied with an app designed for this study and a pedometer. The control group did not have access to functionalities related to the self-monitoring of weight at home, gamification, or prescription of PA. The intervention group members were assigned objectives to achieve a degree of compliance with diet and PA through exclusive access to specific functionalities of the app and push notifications. The same diet was prescribed for all patients. Three possible PA scenarios were studied for both the control and intervention groups: light physical activity (LPA), moderate physical activity (MPA), and intense physical activity (IPA). For the analysis of three or more means, the analysis of variance (ANOVA) of repeated means was performed to evaluate the effects of the intervention at baseline and at 3 and 6 months. RESULTS Receiving notifications during the intervention increased body fat loss (mean -12.9% [SD 6.7] in the intervention group vs mean -7.0% [SD 5.7] in the control group; P<.001) and helped to maintain muscle mass (mean -0.8% [SD 4.5] in the intervention group vs mean -3.2% [SD 2.8] in the control group; P<.018). These variations between groups led to a nonsignificant difference in weight loss (mean -7.9 kg [SD 3.9] in the intervention group vs mean -7.1 kg [SD 3.4] in the control group; P>.05). CONCLUSIONS Push notifications have proven effective in the proposed weight loss program, leading women who received them to achieve greater loss of fat mass and a maintenance or increase of muscle mass, specifically among those who followed a program of IPA. Future interventions should include a longer evaluation period; the impact of different message contents, as well as message delivery times and frequency, should also be researched. CLINICALTRIAL ClinicalTrials.gov NCT03911583; https://www.clinicaltrials.gov/ct2/show/NCT03911583

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