Low concentration acetamiprid-induced oxidative stress hinders the growth and development of silkworm posterior silk glands

2021 ◽  
pp. 104824
Author(s):  
Zhengting Lu ◽  
Wentao Ye ◽  
Piao Feng ◽  
Minli Dai ◽  
Dandan Bian ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Growth And Development ◽  
Low Concentration ◽  
Silk Glands

Exploring the Potentials of Antioxidants in Retarding Ageing

2017 ◽  
pp. 166-195 ◽  
Author(s):  
Minu Kesheri ◽  
Swarna Kanchan ◽  
Rajeshwar P. Sinha
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Growth And Development ◽  
Aging Process ◽  
Reactive Oxygen ◽  
Normal Growth ◽  
Antioxidant Defenses ◽  
Oxygen Species ◽  
Biotic Stresses ◽  
Living Organisms

In retrospect to the rise in the occurrence of ageing related disorders and the everlasting desire to overcome ageing, exploring the causes, mechanisms and therapies to curb ageing becomes relevant. Reactive Oxygen Species (ROS) are commonly generated during normal growth and development. However abiotic and biotic stresses enhance the level of ROS which in turn pose the threat of oxidative stress. Ability to perceive ROS and to speedily commence antioxidant defenses is crucial for the survival as well as longevity of living cells. Therefore living organisms are bestowed with antioxidants to combat the damages caused by oxidative stress. This chapter aims to elucidate an overview of the process of ageing, generation and enhancement of reactive oxygen species, damages incurred by oxidative stress, its amelioration strategies, therapeutic and biotechnological potentials of antioxidants and various sources of bioactive compounds significant in retardation of aging process.

Spermidine alleviates oxidative stress in silk glands of Bombyx mori

2016 ◽  
Vol 19 (4) ◽  
pp. 1197-1202 ◽  
Author(s):  
Aparna Yerra ◽  
Surekha Challa ◽  
Satyavathi V. Valluri ◽  
Anitha Mamillapalli
Keyword(s):  
Oxidative Stress ◽  
Bombyx Mori ◽  
Silk Glands

A review of ascorbic acid potentialities against oxidative stress induced in plants

2011 ◽  
Vol 28 (2) ◽  
pp. 97-111 ◽  
Author(s):  
Taqi Khan ◽  
Mohd Mazid ◽  
Firoz Mohammad
Keyword(s):  
Oxidative Stress ◽  
Ascorbic Acid ◽  
Plant Growth ◽  
Growth And Development ◽  
Crop Production ◽  
Ultra Violet ◽  
Environmental Stresses ◽  
Plant Growth And Development ◽  
Cellular Mechanisms ◽  
Oxidative Stresses

A review of ascorbic acid potentialities against oxidative stress induced in plantsAscorbic acid (AA) currently holds a significant position in plant physiology, mainly due to its possession of antioxidant and cellular reductant etc.properties and its diverse roles in plant growth and development and the regulation of a broad spectrum of plant cellular mechanisms against environmental stresses. Some researchers suggest that endogenous AA has been implicated in the promotion of plant growth and development by involvement in a complex and enigmatic array of phytohormone-regulated signalling networks that ties together different environmental stresses. As it is evident from the present review, recent progress on AA potentiality in the tolerance of plants to environmental stresses has been impressive. Indeed, AA plays an important role in resistance to oxidative stresses such as heavy metal, saline, ultra-violet etc. Rapidly increasing evidence indicates that AA is centrally involved in several physiological processes but there has been much disagreement regarding the mechanism(s) by which AA reduces the damaging effects of such stresses in plants. Perhaps the role of AA in mediating tolerance to abiotic stress (e.g. UV, salinity and temperature, etc.) will lead to a greater research focus in the near future. In addition, AA might provide a suitably attractive target for the enhancement of crop production.

scholarly journals Low-concentration T-2 Toxin Attenuates Pseudorabies Virus Replication in Porcine Kidney 15 Cells

2021 ◽  
Author(s):  
Kuankuan Xiong ◽  
Lei Tan ◽  
Siliang Yi ◽  
Yingxin Wu ◽  
Yi Hu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Pseudorabies Virus ◽  
Low Dose ◽  
Cell Injury ◽  
Interaction Mechanism ◽  
Protective Effects ◽  
Porcine Kidney ◽  
Low Concentration ◽  
New Ideas ◽  
And Control

Abstract Pseudorabies, caused by pseudorabies virus (PRV), is the main highly infectious disease that severely affects the pig industry globally. T-2 toxin (T2), a significant mycotoxin, is widely spread in food and feeds and shows high toxicity to mammals. The potential mechanism of the interaction between viruses and toxins is of great research value because revealing this mechanism may provide new ideas for their joint prevention and control. In this study, we investigated the effect of T2 on PRV replication and the mechanism of action. The results showed that at a low dose (10 nM) T2 had no significant effect on porcine kidney 15 (PK15) cell viability. However, this T2 concentration alleviated PRV-induced cell injury and increased cell survival time. Additionally, the number of PK15 cells infected with PRV was significantly reduced by T2 treatment. Similarly, T2 significantly decreased the copy number of PRV. Investigation of the mechanism revealed that 10 nM T2 significantly inhibited PRV replication and led to downregulation of oxidative stress- and apoptosis-related genes. These results suggest that oxidative stress and apoptosis are involved in the inhibition of PRV replication in PK15 cells by low-concentration T2. Taken together, we demonstrated the protective effects of T2 against PRV infection. A low T2 concentration inhibited the replication of PRV in PK15 cells, and this process was accompanied by downregulation of by the oxidative stress and apoptosis signaling pathways. Our findings partly explain the interaction mechanism between T2 and PRV, relating to oxidative stress and apoptosis, though further research is required.

scholarly journals Chickpea Ferritin CaFer1 Participates in Oxidative Stress Response and Promotes Growth and Development

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Shaista Parveen ◽  
Deepti Bhushan Gupta ◽  
Suchismita Dass ◽  
Amit Kumar ◽  
Aarti Pandey ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Stress Response ◽  
Growth And Development ◽  
Oxidative Stress Response

scholarly journals The Role of NFκB in Healthy and Preeclamptic Placenta: Trophoblasts in the Spotlight

2020 ◽  
Vol 21 (5) ◽  
pp. 1775 ◽  
Author(s):  
Brooke Armistead ◽  
Leena Kadam ◽  
Sascha Drewlo ◽  
Hamid-Reza Kohan-Ghadr
Keyword(s):  
Oxidative Stress ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth And Development ◽  
Protein Family ◽  
Growth Restriction ◽  
Placental Development ◽  
Critical Organ ◽  
And Oxidative Stress

The NFκB protein family regulates numerous pathways within the cell—including inflammation, hypoxia, angiogenesis and oxidative stress—all of which are implicated in placental development. The placenta is a critical organ that develops during pregnancy that primarily functions to supply and transport the nutrients required for fetal growth and development. Abnormal placental development can be observed in numerous disorders during pregnancy, including fetal growth restriction, miscarriage, and preeclampsia (PE). NFκB is highly expressed in the placentas of women with PE, however its contributions to the syndrome are not fully understood. In this review we discuss the molecular actions and related pathways of NFκB in the placenta and highlight areas of research that need attention

scholarly journals Effects of toner-handling work on respiratory function, chest X-ray findings, and biomarkers of inflammation, allergy, and oxidative stress: a 10-year prospective Japanese cohort study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Niina Terunuma ◽  
Kazunori Ikegami ◽  
Hiroko Kitamura ◽  
Hajime Ando ◽  
Shizuka Kurosaki ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cohort Study ◽  
Adverse Effects ◽  
Respiratory Function ◽  
Exposure Group ◽  
High Concentration ◽  
X Ray ◽  
Low Concentration ◽  
Chest X Ray ◽  
And Oxidative Stress

Abstract Background Exposure to toner, a substance used in photocopiers and printers, has been associated with siderosilicosis and other adverse effects. However, these findings are limited, and there is insufficient evidence on the long-term effects of toner exposure. Using longitudinal analysis, this study aimed to examine the effects of work involving toner exposure on the respiratory system over time. Methods We conducted a prospective cohort study in a Japanese toner and copier manufacturing enterprise between 2003 and 2013. The cohort included a total of 1468 workers, which comprised 887 toner-handling workers and 581 non-toner-handling workers. We subdivided the toner-handling workers into two groups according to the toner exposure concentration, based on the baseline survey in 2003. We compared the chest X-ray results, respiratory function indicators, and serum and urinary biomarkers of inflammation, allergy, and oxidative stress among the three groups: high-concentration toner exposure group, low-concentration toner exposure group, and non-toner-handling group. To consider the effects of individual differences on the longitudinal data, we used a linear mixed model. Results Similar chest X-ray results, the biomarkers, and most of the respiratory function indicators were found in the non-toner-handling and toner-handling groups. There were no significant yearly changes in the percentage of vital capacity (%VC) in the high-concentration toner exposure group, while there was a significant yearly increase in %VC in the low-concentration toner exposure group and non-toner-handling group. The yearly change in each group was as follows: high-concentration toner exposure group, − 0.11% (95% confidence interval [CI], − 0.29 to 0.08; P = 0.250); low-concentration toner exposure group, 0.13% (95% CI, 0.09–0.17; P < 0.001); and non-toner-handling group, 0.15% (95% CI, 0.01–0.20; P < 0.001). Conclusions In our 10-year prospective study, toner-handling work was not associated with the deterioration of respiratory function and an increase in biomarker values for inflammation, allergy, and oxidative stress. This finding suggests that toner-handling work is irrelevant to the onset of respiratory disease and has minimal adverse effects on the respiratory system under a well-managed work environment.

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