scholarly journals Adverse drug events with iron chelation drugs in thalassemic patients attending a day care thalassemia centre in Tertiary Care Govt. Medical College in North India

2016 ◽  
Vol 1 (2) ◽  
pp. S20
Author(s):  
Kishore Kumar Digra ◽  
Sanjeev Kumar Digra ◽  
Rajesh Kaul ◽  
Subhash Singh Slathia
Author(s):  
Rajeev Mishra ◽  
S. S. Keshari

Background: Pain is an unpleasant sensory and emotional experience which is associated with actual or potential tissue damage or described in such terms. NSAIDs are most commonly prescribed drugs for the treatment of pain and inflammation and is most commonly prescribed drug around the world. NSAIDs are also most commonly used drug over the counter. Present study was done to evaluate the prescription pattern of analgesics and to assess the rational use of conventional non-steroidal anti-inflammatory drugs (NSAIDs), selective cyclooxygenase-2 (COX-2) inhibitors, and opioid analgesics.Methods: Present study was Cross sectional study, done at outdoor department of Orthopaedics at T.S. Misra Medical College and Hospital, Lucknow during January 2017 to April 2017 in a pre-designed and pre-tested proforma. Both male and female patients, above the age of 18 years, who were willing to participate in this study were enrolled. Samples of 253 prescriptions were screened randomly and verbal informed consent was taken. Data were analysed using MS Excel 2007 and summarized as counts and percentages. Statistical analysis was not done as it was a descriptive study.Results: Most commonly prescribed analgesics were non-selective NSAIDs followed by selective COX-2 inhibitors. Most commonly prescribed FDCs combination was diclofenac with paracetamol.Conclusions: This study shows that diclofenac is the most frequently prescribed analgesic in orthopaedics OPD at this hospital. The extensive use of irrational FDCs must be curtailed. We observed in present study that most of the prescriptions were rational. But there are scopes for improvement by introducing appropriate educational intervention for rational prescribing. 


2021 ◽  
Vol 12 (2) ◽  
pp. 140-144
Author(s):  
Neerja Puri ◽  
Sukhmani Kaur Brar ◽  
B. K. Brar

Introduction: Cutaneous metastases may precede a malignancy and, in other cases, herald the recurrence of a malignancy after surgery. Aim: To determine the significance of cutaneous manifestations in patients with an internal malignancy and to observe the various types of carcinomas in patients attending a dermatology OPD. Methods: This was a prospective hospital-based study undertaken to observe the cutaneous features in a dermatology OPD in patients coming from the oncology department of a medical college. Results: The commonest malignancy in males was a lung carcinoma, observed in 5.50% of the patients, followed by a prostate carcinoma, observed in 4.58% of the patients, an esophagus carcinoma, observed in 4.12% of the patients, and a penis carcinoma, observed in 2.29% of the patients. Specific cutaneous manifestations included cutaneous metastatic infiltrates, observed in 5.04% of the patients, and carcinoma erysipeloides, observed in 1.37% of the patients. Discussion: Skin metastases may herald the recurrence of a malignancy after treatment and usually indicate a poor prognosis.


2021 ◽  
Vol 0 ◽  
pp. 1-4
Author(s):  
Rohit Garg ◽  
Aditi Singla ◽  
Jasmin Garg

Objectives: The present study was aimed to assess the level of perceived stress among doctors working in COVID-19 ward in a tertiary care medical college and hospital of North India and to find the association of stress with time spent in ward, age, and designation of the doctors. Material and Methods: It was a cross-sectional, Google-based survey conducted in October and November 2020. The form was circulated and recorded the sociodemographic data, time spent in the COVID-19 ward, etc. The perceived stress scale (PSS) was used to assess the level of stress. Appropriate statistical analysis was used and all ethical considerations were followed. Results: Mean PSS score of the sample was 22.22 ± 7.13. Twenty-five (10%) doctors reported low stress (mean PSS score 0–13). Moderate (mean PSS score 14-26) and high stress (mean PSS score >26) were found among 156 (62.4%) and 69 (27.6%) doctors, respectively. Perceived stress showed significant negative correlation with age and significant positive correlation with hours spent in COVID ward in a week. Senior residents and junior residents had significantly higher perceived stress than faculty (P - 0.001**). Nearly 50% of doctors (fairly often or very often) felt nervous and stressed, angered because they felt out of control, unable to control important things in their lives, and have been upset because of something that happened unexpectedly. About 40% felt (fairly often or very often) that they could not cope with all the things they had to do. Nearly one-third of doctors felt (fairly or very often) that difficulties were piling up so high that they could not overcome them. Conclusion: Doctors working in COVID-19 wards perceive considerable stress. Stress management should be an integral part of the curriculum of doctors so that they can serve the humanity efficiently and effectively during the pandemic and in future.


Author(s):  
Prachi Sarin Sethi ◽  
Sujata Sharma ◽  
Indu Chawla

Background: Early detection of abnormal progress and prevention of prolonged labour can significantly improve the outcome of labour. Partograph is an inexpensive tool which can provide a continuous pictorial overview of labour and is essential to monitor and manage labour. The objectives were to study the course of normal and abnormal labour and to evaluate the maternal and perinatal outcome using simple and composite WHO partogram.Methods: This was a randomized study conducted at Department of Obstetrics and Gynaecology, Government Medical College, Amritsar, a tertiary care centre in North India. 200 women with term, singleton, vertex gestation, in spontaneous labor were included in the study. In 100 cases composite partograph was plotted and in rest 100 cases simple partograph was plotted. The following outcomes were compared: labor crossing the alert and action line, augmentation of labor, rate of cesarean section, perinatal and maternal outcome.Results: The partogram crossed the alert line (p 0.008) and action lines (p 0.017), causing increased need for augmentation (p 0.034) in the composite partogram which was statistically significant. The numbers of vaginal deliveries were high (p<0.001) and decrease number of cesarean sections (p 0.007) and instrumental deliveries (p 0.009) in the simplified group. NICU admissions were also higher in the composite group (p<0.05), though most of the NICU admissions were due to hyperbilirubinemia and low birth weight and was not directly related to monitoring of labour.Conclusions: It was observed in the present study that labour can be managed without the latent phase being plotted on the partograph. The interventions were higher when the latent phase was included, with increased number of labours crossing the alert and action lines, increased no. of augmentations and larger number of caesarean sections. Our study favours the use of the WHO modified partograph, which should become routine practice in monitoring labour for better maternal and perinatal outcome.


Author(s):  
Jayanthi C. R. ◽  
Mohammed Yaqub Pasha ◽  
Sushma M.

Background: Adverse drug event (ADE) is said to be serious, when it is life-threatening, leads to hospitalization, disability, congenital anomaly, death or requires intervention to prevent permanent impairment or damage. The present study aimed to determine the pattern, causality, preventability of serious ADEs.Methods: This retrospective study was carried out to profile serious ADEs reported from Bangalore Medical College and Research Institute to Adverse Drug Reaction (ADR) Monitoring Centre, under Pharmacovigilance Programme of India from 2012 to 2016. Patient demographics, clinical and drug data, details of the ADE, onset time, causal drug details, outcome and severity were collected as per CDSCO form. Causality was assessed by WHO-ADR probability scale, preventability by modified Schumock and Thornton scale.Results: A total of 809 ADEs were reported, of which 50 (6.18%) were serious in nature. Male preponderance (74%) was observed, with 42% among patients aged 20-40 years. 56% of serious ADEs were reported from department of Dermatology. Steven Johnson Syndrome (SJS) (20%) contributed for most of the ADEs. Antiepileptics caused maximum number of serious ADEs (32%). 76% of the ADEs were found to be ‘probable’ and 4% were definitely preventable. 56% of them was life threatening and 86% required intensive interventions. 16% patients experienced serious ADEs during hospital stay.Conclusions: Serious ADEs constituted 6.18% of all ADEs reported. SJS was commonly seen with antimicrobials and hepatotoxicity with ATT. Antiepileptics and ATT contributed for majority of them. This study highlights the importance of monitoring and timely management of serious ADEs to commonly prescribed medications.


Author(s):  
Sadat Ullah Khan ◽  
Fauzia Arif

Background: Day care surgery offers advantages for health care delivery system around the world and so rates have steadily increased in both developed and developing countries. Methods: This study has been done in a single unit of the Department of General surgery at S M S Medical college, Jaipur on patients attending the OPD as well as admitted for surgery Results: There was no age limit in our study. Out of 100 patients 11 were of age group 0-20 years, 55 were of age group 21-40 years, 25 were of age group 41-60 years, 9 were of age group >60 years. Conclusion: Age and sex was not any criteria for patient selection for day care surgery. Keywords: Age, Sex, Distance.


Author(s):  
Ishfaq Chodhary ◽  
Tariq Ahmed Mala ◽  
Tasleem Arif

Background: Vitamin D is unique among vitamins as it can be synthesized from the action of ultra-violet radiation (UVR) upon the skin of human beings. This study was done to investigate the prevalence of vitamin D deficiency among health care professionals.Methods: This was institution based study conducted over a period of two years at Govt. Medical College Hospital. The study was conducted on 200 healthy doctors working in different departments of Govt. Medical College and Associated Hospitals, Jammu for a period of two years. Data regarding demographic characteristics, lifestyle assessment, exposure to sunshine on workdays and weekends, type of clothing, use of sunscreen, subjective general health, dietary assessment and use of calcium or vitamin D supplements was collected using a structured questionnaire.Results: Mean value of age of study subjects was 26.18±2.09 years. Results showed that 50% were male and 50% were females. In this study, 65.50% of the study subjects were Hindu and 30% of study subjects were Muslim. Majority of the study subjects had exposure to sunlight for less than 20 minutes and only 10 out of 200 study subjects had exposure to sunlight for more than 30 minutes. In this study, 97% of the study subjects were vitamin D deficient and only 3% were vitamin D sufficient. Among 196 study subjects with vitamin D deficiency, severe deficiency was present in 30.41% (59 out of 194) of study subjects, moderate deficiency was present in 60.82% (118 out of 194) of study subjects and very few study subjects had mild vitamin D deficiency.Conclusions: Vitamin D deficiency is highly prevalent among healthy medical college students. Lack of awareness regarding importance of vitamin D requirement, inadequate exposure to sunlight, changes in lifestyle and food habits contribute to low vitamin D levels in young population.


Sign in / Sign up

Export Citation Format

Share Document