Surface characteristics of porous titanium implants fabricated by environmental electro-discharge sintering of spherical Ti powders in a vacuum atmosphere

2005 ◽  
Vol 53 (8) ◽  
pp. 905-908 ◽  
Author(s):  
Y.B. An ◽  
N.H. Oh ◽  
Y.W. Chun ◽  
Y.H. Kim ◽  
J.S. Park ◽  
...  
Keyword(s):  
Surface Characteristics ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Vacuum Atmosphere

scholarly journals Advanced production techniques and designing of porous titanium bio implants and scaffolds

2019 ◽  
Vol 8 (4) ◽  
pp. 698-703
Keyword(s):  
Power Efficiency ◽  
Raw Materials ◽  
Manufacturing Sector ◽  
High Strength ◽  
Surface Characteristics ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Production Techniques ◽  
Manufacturing Techniques ◽  
Traditional Manufacturing

Traditional manufacturing processes such as casting and machining are being largely replaced by the advanced manufacturing techniques such as ALM and MIM in the bio-implant manufacturing sector due to their design flexibility, minimum wastage of raw materials, power efficiency, ability to produce complex porous structures and accuracy. These techniques suffer from drawbacks due to their high market cost and low surface finish of the implant produced. Porous titanium implants/scaffolds are being extensively manufactured by these advanced techniques due to their high strength, high corrosion resistance, better surface characteristics for bio attachments and biocompatibility. By making porous, the density and strength of the bio scaffolds/implants can be matched with the surrounding tissues and bones for greater grip and provisions for bone in-growth. In this paper, the current designing and production methods of porous titanium bio implants and scaffolds are being described in detail. In the designing phase of the implants, topology optimization is playing a crucial role in increasing the flexibility in design by eliminating the need fortrial and error method for improved biocompatibility and mechanical property.

Soft Tissue Responses and Attachment to Porous Titanium with Different Surface Characteristics

2006 ◽  
Vol 9 (2) ◽  
pp. 127-134
Author(s):  
Yao Wu ◽  
Hu Li ◽  
Tun Yuan ◽  
Chunlin Deng ◽  
Bangcheng Yang ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Surface Characteristics ◽  
Porous Titanium ◽  
Tissue Responses

scholarly journals Combining Sandblasting, Alkaline Etching, and Collagen Immobilization to Promote Cell Growth on Biomedical Titanium Implants

Polymers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2550
Author(s):  
Chia-Fei Liu ◽  
Kai-Chun Chang ◽  
Ying-Sui Sun ◽  
Diem Thuy Nguyen ◽  
Her-Hsiung Huang
Keyword(s):  
Cell Growth ◽  
Type I Collagen ◽  
Bone Cells ◽  
Surface Characteristics ◽  
Attenuated Total Reflection ◽  
Titanium Implants ◽  
Type I ◽  
Alkaline Etching ◽  
Marrow Mesenchymal Stem Cells ◽  
Collagen Immobilization

Our objective in this study was to promote the growth of bone cells on biomedical titanium (Ti) implant surfaces via surface modification involving sandblasting, alkaline etching, and type I collagen immobilization using the natural cross-linker genipin. The resulting surface was characterized in terms topography, roughness, wettability, and functional groups, respectively using field emission scanning electron microscopy, 3D profilometry, and attenuated total reflection-Fourier transform infrared spectroscopy. We then evaluated the adhesion, proliferation, initial differentiation, and mineralization of human bone marrow mesenchymal stem cells (hMSCs). Results show that sandblasting treatment greatly enhanced surface roughness to promote cell adhesion and proliferation and that the immobilization of type I collagen using genipin enhanced initial cell differentiation as well as mineralization in the extracellular matrix of hMSCs. Interestingly, the nano/submicro-scale pore network and/or hydrophilic features on sandblasted rough Ti surfaces were insufficient to promote cell growth. However, the combination of all proposed surface treatments produced ideal surface characteristics suited to Ti implant applications.

scholarly journals Understanding long-term silver release from surface modified porous titanium implants

2017 ◽  
Vol 58 ◽  
pp. 550-560 ◽  
Author(s):  
Anish Shivaram ◽  
Susmita Bose ◽  
Amit Bandyopadhyay
Keyword(s):  
Porous Titanium ◽  
Titanium Implants ◽  
Silver Release ◽  
Surface Modified

scholarly journals Titanium oral implants: surface characteristics, interface biology and clinical outcome

2010 ◽  
Vol 7 (suppl_5) ◽  
Author(s):  
Anders Palmquist ◽  
Omar M. Omar ◽  
Marco Esposito ◽  
Jukka Lausmaa ◽  
Peter Thomsen
Keyword(s):  
Surface Properties ◽  
Cellular Response ◽  
Randomized Clinical Trials ◽  
Three Dimensional ◽  
Cell Communication ◽  
Surface Characteristics ◽  
Titanium Implants ◽  
Material Surface ◽  
Oral Implants

Bone-anchored titanium implants have revolutionized oral healthcare. Surface properties of oral titanium implants play decisive roles for molecular interactions, cellular response and bone regeneration. Nevertheless, the role of specific surface properties, such as chemical and phase composition and nanoscale features, for the biological in vivo performance remains to be established. Partly, this is due to limited transfer of state-of-the-art preparation techniques to complex three-dimensional geometries, analytical tools and access to minute, intact interfacial layers. As judged by the available results of a few randomized clinical trials, there is no evidence that any particular type of oral implant has superior long-term success. Important insights into the recruitment of mesenchymal stem cells, cell–cell communication at the interface and high-resolution imaging of the interface between the surface oxide and the biological host are prerequisites for the understanding of the mechanisms of osseointegration. Strategies for development of the next generation of material surface modifications for compromised tissue are likely to include time and functionally programmed properties, pharmacological modulation and incorporation of cellular components.

scholarly journals Electrical Impedance of Surface Modified Porous Titanium Implants with Femtosecond Laser

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 461
Author(s):  
Paula Navarro ◽  
Alberto Olmo ◽  
Mercè Giner ◽  
Marleny Rodríguez-Albelo ◽  
Ángel Rodríguez ◽  
...  
Keyword(s):  
Cell Culture ◽  
Femtosecond Laser ◽  
Laser Treatment ◽  
Electrical Impedance ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Electrical Impedance Spectroscopy ◽  
Wide Range ◽  
Titanium Surfaces ◽  
Surface Modified

The chemical composition and surface topography of titanium implants are essential to improve implant osseointegration. The present work studies a non-invasive alternative of electrical impedance spectroscopy for the characterization of the macroporosity inherent to the manufacturing process and the effect of the surface treatment with femtosecond laser of titanium discs. Osteoblasts cell culture growths on the titanium surfaces of the laser-treated discs were also studied with this method. The measurements obtained showed that the femtosecond laser treatment of the samples and cell culture produced a significant increase (around 50%) in the absolute value of the electrical impedance module, which could be characterized in a wide range of frequencies (being more relevant at 500 MHz). Results have revealed the potential of this measurement technique, in terms of advantages, in comparison to tiresome and expensive techniques, allowing semi-quantitatively relating impedance measurements to porosity content, as well as detecting the effect of surface modification, generated by laser treatment and cell culture.

scholarly journals Full regeneration of segmental bone defects using porous titanium implants loaded with BMP-2 containing fibrin gels

2015 ◽  
Vol 29 ◽  
pp. 141-154 ◽  
Author(s):  
J van der Stok ◽  
◽  
MKE Koolen ◽  
MPM de Maat ◽  
S Amin Yavari ◽  
...  
Keyword(s):  
Bone Defects ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Fibrin Gels ◽  
Segmental Bone ◽  
Segmental Bone Defects

Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone

2018 ◽  
Vol 6 (15) ◽  
pp. 2274-2288 ◽  
Author(s):  
Xiao-Fan Hu ◽  
Ya-Fei Feng ◽  
Geng Xiang ◽  
Wei Lei ◽  
Lin Wang
Keyword(s):  
Lactic Acid ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Bone Implant ◽  
3D Printed

PLGA-coating on 3D-printed porous titanium implants promoted the angiogenesis and osteointegration at bone-implant interface in diabetes by releasing lactic acid.

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