P117. Bone density distribution in the cervical spine: Establishing level specific reference values

2021 ◽  
Vol 21 (9) ◽  
pp. S197-S198
Author(s):  
Francis C. Lovecchio ◽  
Bryan Ang ◽  
Philip Louie ◽  
Chirag Chaudhary ◽  
Sachin Shah ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Bone Density ◽  
Density Distribution ◽  
Reference Values ◽  
Specific Reference

scholarly journals Glycemic Variability and Its Association With Demographics and Lifestyles in a General Adult Population

2016 ◽  
Vol 11 (4) ◽  
pp. 780-790 ◽  
Author(s):  
Francisco Gude ◽  
Pablo Díaz-Vidal ◽  
Cintia Rúa-Pérez ◽  
Manuela Alonso-Sampedro ◽  
Carmen Fernández-Merino ◽  
...  
Keyword(s):  
Physical Activity ◽  
Reference Values ◽  
Smoking Status ◽  
Clinical Care ◽  
Adult Population ◽  
Heavy Drinking ◽  
Glycemic Variability ◽  
Specific Reference ◽  
Cross Sectional ◽  
General Adult Population

Objective: The objective was to investigate glycemic variability indices in relation to demographic factors and common environmental lifestyles in a general adult population. Methods: The A Estrada Glycation and Inflammation Study is a cross-sectional study covering 1516 participants selected by sampling of the population aged 18 years and over. A subsample of 622 individuals participated in the Glycation project, which included continuous glucose monitoring procedures. Five glycemic variability indices were analyzed, that is, SD, MAGE, MAG, CONGA1, and MODD. Results: Participants had a mean age of 48 years, 62% were females, and 12% had been previously diagnosed with diabetes. In the population without diabetes, index distributions were not normal but skewed to the right. Distributional regression models that adjusted for age, gender, BMI, alcohol intake, smoking status, and physical activity confirmed that all indices were positively and independently associated with fasting glucose levels and negatively with heavy drinking. SD, MAGE, and CONGA1 were positively associated with aging, and MAG was negatively associated with BMI. None of the GVI studied were influenced by physical activity. Age-group-specific reference values are given for the indices. Conclusions: This study yielded age-specific reference values for glucose variability indices in a general adult population. Significant increases were observed with aging. Heavy drinking of more than 140 g/week was associated with significant decreases in variability indices. No differences were found between males and females. These normative ranges provide a guide for clinical care, and may offer an alternative treatment target among persons with diabetes.

Abstract 170: Re-evaluation of Carotid Intima-Media Thickness by Z-score in Children and Adolescents After Kawasaki Disease

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Nobutaka Noto ◽  
Masataka Kato ◽  
Yuriko Abe ◽  
Hiroshi Kamiyama ◽  
Kensuke Karasawa ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Children And Adolescents ◽  
Reference Values ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Specific Reference ◽  
Healthy Children ◽  
Media Thickness ◽  
Z Scores ◽  
The Mean

Objectives: The carotid intima-media thickness (CIMT) is a reliable screening method for vascular alterations even in a pediatric cohort; however, reference values of CIMT established recently by LMS methods for childhood and adolescence are limited when comparing patients after Kawasaki disease (KD) and controls. We tested the hypothesis that there are significant differences between the values of CIMT expressed as absolute values and z-scores in children and adolescents after KD and controls. Methods: We reviewed 12 published articles regarding CIMT on patients after KD and controls. Absolute values (Ab) of the mean±1 SD of CIMT in patients after KD and controls were transformed to z-scores (Zs) using age-specific reference values established by Jourdan et al. (J: 247 Caucasian subjects aged 10-20 years) and our own data (O: 175 Asian subjects aged 6-20 years), and the results were compared between the two references. In this study, the mean age of the study population derived from each article was designated the representative age for transformation. Results: In either reference (J) or (O), there was no significant sex difference in CIMT at any given age. The mean CIMT of (Ab) and (Zs) transformed by (J) or (O) were significantly different between patients after KD and controls, at 41.6% (Ab), 66.6% (Zs) by (J), and 83.3% (Zs) by (O) among 12 articles, respectively. Therefore, patients after KD had significantly higher (Zs) by (O) than those of controls (0.66±0.71 vs. 0.03±0.68, p=0.006, respectively). Compared with reference values, the controls of (O) were within the normal range. However, there were no significant differences in (Zs) by (J) between the two groups (1.72±0.77 vs. 1.23±0.83, p=0.116, respectively). When we assessed 9 articles dealing with Asian subjects, the difference of (Zs) between the two groups remained significant only by (O) (p=0.015). In contrast, when we assessed 3 articles dealing with mainly Caucasian subjects, there was no significant difference in (Zs) between the two groups with both (J) and (O). Conclusions: These results indicate that age and race-specific reference values for CIMT are mandatory for performing an accurate assessment of the vascular status in healthy children and adolescents and particularly in those after KD.

scholarly journals Study of thyroid volume by ultrasonography in clinically euthyroid patients

1970 ◽  
Vol 32 (2) ◽  
pp. 36-43 ◽  
Author(s):  
P Kayastha ◽  
S Paudel ◽  
DM Shrestha ◽  
RJ Ghimire ◽  
S Pradhan
Keyword(s):  
Surface Area ◽  
Body Surface Area ◽  
Reference Values ◽  
Body Surface ◽  
Pearson Correlation ◽  
Thyroid Volume ◽  
Specific Reference ◽  
Reference Ranges ◽  
Hilly Region ◽  
Significant Difference

Introduction: The purpose of this study was to establish reference ranges of total thyroid volume among clinically euthyroid Nepalese population using Ultrasonography and correlate this volume with age, sex, individual’s built and geographic location. Methods: This was a prospective cross sectional study involving 485 clinically euthyroid individuals. B - mode Ultrasonography was used to measure the total thyroid volume by combining the volume of both the lobes obtained by using formula for prolate ellipsoid. Age specific reference values for thyroid volume were obtained and Pearson correlation test was used to see the relationship with various factors. Results: Among 485 individuals between 1 to 83 years of age, 221(45.57%) were males and 264(54.43%) were females. Maximum [354 individuals (72.99%)] were from hilly region and minimum [16 individual (3.30%)] were from Himalayan region. Mean thyroid volume was 6.629 ± 2.5025 ml. In general, thyroid volume was found to be more in older individuals than in young age group. There was no significant difference of thyroid volume between males and females. Thyroid volume best correlated with body surface area (r=0.444, p<0.0001). The volume had a positive correlation with weight (r=0.443, p<0.0001), body mass index (r=0.371, p<0.0001) and height (r=0.320, p<0.0001) of the individual. Conclusions: This study estimated the reference range of total thyroid volume for Nepalese population. These ranges are significantly lower than the WHO/ICCIDD thyroid volume references and reference values obtained in various other countries. Total thyroid volume best correlated with Body surface area. Keywords: Body surface area; clinically euthyroid; total thyroid volume; ultrasonography DOI: http://dx.doi.org/10.3126/joim.v32i2.4944 Journal of Institute of Medicine, August, 2010; 32: 36-43

scholarly journals Spatial Subchondral Bone Density Reflecting Joint Loading of the Talus in Different Canidae

2019 ◽  
Vol 32 (03) ◽  
pp. 207-214
Author(s):  
Walter Dingemanse ◽  
Ingrid Gielen ◽  
Henri van Bree ◽  
Magdalena Müller-Gerbl ◽  
Nikola Krstić ◽  
...  
Keyword(s):  
Bone Density ◽  
Density Distribution ◽  
Subchondral Bone ◽  
Canis Lupus ◽  
Joint Loading ◽  
German Shepherd ◽  
Canis Aureus ◽  
Joint Biomechanics ◽  
Subchondral Bone Density

Objective Subchondral bone density distribution can be used to study joint biomechanics non-invasively. Differences in joint loading between related species can aid in the understanding of joint loading and the development of certain types of orthopaedic pathology. This study was conducted to evaluate density distribution in the subchondral bone of the talus of different Canidae species, as a parameter reflecting the long-term joint loading in the tarsocrural joint. Materials and Methods The tarsal joints of cadaveric dogs of different breeds were included, that is, German Shepherd (n = 5), Bouvier des Flandres (n = 3) and Labrador Retriever (n = 6).Additionally, golden jackals (n = 5) (Canis aureus) and wolves (n = 5) (Canis lupus) were included. Consecutive computed tomography slices were made and the subchondral bone density distribution was evaluated using computer tomographic osteoabsorptiometry. Different breeds and species were visually compared. Results Differences were found in the subchondral bone density distribution of the talus between breeds and between species (Canis familiaris, Canis lupus and Canis aureus). Discussion and Conclusion Based on the density distribution, there are differences in loading conditions of the tarsocrural joint in different species of Canidae. The joint loading distribution is very similar between dogs of the same breed and within the same species. Although between-breed differences can be explained by conformational differences, the between-species differences remain subject to further research.

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